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The map label for this gene is appC [H]

Identifier: 158424285

GI number: 158424285

Start: 3015259

End: 3016269

Strand: Direct

Name: appC [H]

Synonym: AZC_2661

Alternate gene names: 158424285

Gene position: 3015259-3016269 (Clockwise)

Preceding gene: 158424284

Following gene: 158424286

Centisome position: 56.15

GC content: 69.93

Gene sequence:

>1011_bases
ATGACCAAGAGCCAAGCCCTCCCCGCTCCCGCCACGCTGGAGCATCCGTCCTCCGGCCCCGCCGCCCTCCCGGCCGCCGG
CACCGGCGATCTCGCCAACTGGCCCAATGTGCACGCCCCCGATGCGGCACGGGCCACCGAACAGGCCGTGGAGCGTCTCG
CCCCCTCCGGCCGCCACCGCGCGCTGCGCGCCTTCCTCACCAATCCCAACGCCGTGGCGGGCAGCCTCATTCTCCTCGCC
GTGCTGGCCGCCGCGCTCGCCGCGCCCATCCTCTATCCGGACGATCCGCTGGAAATGGCGGGCCGCCCTCTGATCTGGCC
GGGCCAGTCGCCGGAATTTCCCCTCGGCACCGATGCCCTCGGGCGTGACGTGGCAGCCGGCGTGTTCCATGGCGCGCGGG
TGAGCCTGCTCGTCGGCGCGATGGCGACCATCGTCAGCCTGCTGGCGGGGACGCTGGTGGGCGCGCTCGCCGGCTATTTC
GGCGGCCGGACGGATGATGTGCTGGTGAAGCTCATCGAGGTCTTCCAGACCATTCCGGGCTTCATATTGCTCATCGTGCT
GGTGGCCATCGCCCAGCCCTCCATTCCCGCCATCACGCTTGCCATCGGCCTCGTTTCCTGGCCCTCGGTGGCGCGTCTCG
TGCGGGCGCAGTTCCGTTCGCTGCGGGAGAAGGATTTCGTCATGGCCGCGCGCGGGCTCGGCTACGGGCACGGGCGCATC
ATCTTCCGCGAGATCCTTCCCAACGCCCTGCCGCCGGTCATTGTCATGGCATCGGTGACGGTGGCCACCGCCATCCTCAT
GGAAAGCGCGCTCTCCTTCATGGGGCTCGGCGATCCGAACGTGGTGAGCTGGGGCTCCATGATCGGCGCCGGGCGCGAGA
TGCTGCGCACCGCCTGGTATCTCAGCGCCGTGCCGGGCCTTGCCATCGTCTTCACCGTGCTCTCGCTCAACCTCATCGGC
GACGGGCTCAATGACGCGCTGAACCCGCGCCTGTCCGGGGAGCGCCGCTGA

Upstream 100 bases:

>100_bases
TGCTCGGCATCCTCCTTCTCTCGTCCCTGCTGGTGGTCGCGGTCAATGCGTTGATCGACCTCTTCCAGGCCTGGCTCGAC
CCGCGGATCGAGGTGCGCTG

Downstream 100 bases:

>100_bases
TGGCCCCGCTGCTCGACGTACGCGATCTCTCCATCGCCTTTCCCCGCGCCACGCCCGTGCGCGGCCTCTCGCTCACCGTG
GAGCAAGGCGAAACCGTGGC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTKSQALPAPATLEHPSSGPAALPAAGTGDLANWPNVHAPDAARATEQAVERLAPSGRHRALRAFLTNPNAVAGSLILLA
VLAAALAAPILYPDDPLEMAGRPLIWPGQSPEFPLGTDALGRDVAAGVFHGARVSLLVGAMATIVSLLAGTLVGALAGYF
GGRTDDVLVKLIEVFQTIPGFILLIVLVAIAQPSIPAITLAIGLVSWPSVARLVRAQFRSLREKDFVMAARGLGYGHGRI
IFREILPNALPPVIVMASVTVATAILMESALSFMGLGDPNVVSWGSMIGAGREMLRTAWYLSAVPGLAIVFTVLSLNLIG
DGLNDALNPRLSGERR

Sequences:

>Translated_336_residues
MTKSQALPAPATLEHPSSGPAALPAAGTGDLANWPNVHAPDAARATEQAVERLAPSGRHRALRAFLTNPNAVAGSLILLA
VLAAALAAPILYPDDPLEMAGRPLIWPGQSPEFPLGTDALGRDVAAGVFHGARVSLLVGAMATIVSLLAGTLVGALAGYF
GGRTDDVLVKLIEVFQTIPGFILLIVLVAIAQPSIPAITLAIGLVSWPSVARLVRAQFRSLREKDFVMAARGLGYGHGRI
IFREILPNALPPVIVMASVTVATAILMESALSFMGLGDPNVVSWGSMIGAGREMLRTAWYLSAVPGLAIVFTVLSLNLIG
DGLNDALNPRLSGERR
>Mature_335_residues
TKSQALPAPATLEHPSSGPAALPAAGTGDLANWPNVHAPDAARATEQAVERLAPSGRHRALRAFLTNPNAVAGSLILLAV
LAAALAAPILYPDDPLEMAGRPLIWPGQSPEFPLGTDALGRDVAAGVFHGARVSLLVGAMATIVSLLAGTLVGALAGYFG
GRTDDVLVKLIEVFQTIPGFILLIVLVAIAQPSIPAITLAIGLVSWPSVARLVRAQFRSLREKDFVMAARGLGYGHGRII
FREILPNALPPVIVMASVTVATAILMESALSFMGLGDPNVVSWGSMIGAGREMLRTAWYLSAVPGLAIVFTVLSLNLIGD
GLNDALNPRLSGERR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787760, Length=271, Percent_Identity=34.6863468634686, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787498, Length=300, Percent_Identity=37, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789964, Length=274, Percent_Identity=40.5109489051095, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1789889, Length=225, Percent_Identity=33.7777777777778, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=34.8623853211009, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787549, Length=290, Percent_Identity=29.6551724137931, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35011; Mature: 34880

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00626 RCC1_2 ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSQALPAPATLEHPSSGPAALPAAGTGDLANWPNVHAPDAARATEQAVERLAPSGRHR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
ALRAFLTNPNAVAGSLILLAVLAAALAAPILYPDDPLEMAGRPLIWPGQSPEFPLGTDAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEECCCCCCCCCCCCHHH
GRDVAAGVFHGARVSLLVGAMATIVSLLAGTLVGALAGYFGGRTDDVLVKLIEVFQTIPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FILLIVLVAIAQPSIPAITLAIGLVSWPSVARLVRAQFRSLREKDFVMAARGLGYGHGRI
HHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IFREILPNALPPVIVMASVTVATAILMESALSFMGLGDPNVVSWGSMIGAGREMLRTAWY
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LSAVPGLAIVFTVLSLNLIGDGLNDALNPRLSGERR
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
TKSQALPAPATLEHPSSGPAALPAAGTGDLANWPNVHAPDAARATEQAVERLAPSGRHR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
ALRAFLTNPNAVAGSLILLAVLAAALAAPILYPDDPLEMAGRPLIWPGQSPEFPLGTDAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEECCCCCCCCCCCCHHH
GRDVAAGVFHGARVSLLVGAMATIVSLLAGTLVGALAGYFGGRTDDVLVKLIEVFQTIPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FILLIVLVAIAQPSIPAITLAIGLVSWPSVARLVRAQFRSLREKDFVMAARGLGYGHGRI
HHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IFREILPNALPPVIVMASVTVATAILMESALSFMGLGDPNVVSWGSMIGAGREMLRTAWY
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LSAVPGLAIVFTVLSLNLIGDGLNDALNPRLSGERR
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]