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The map label for this gene is prpC [H]

Identifier: 158424207

GI number: 158424207

Start: 2910195

End: 2910926

Strand: Direct

Name: prpC [H]

Synonym: AZC_2583

Alternate gene names: 158424207

Gene position: 2910195-2910926 (Clockwise)

Preceding gene: 158424206

Following gene: 158424208

Centisome position: 54.2

GC content: 69.67

Gene sequence:

>732_bases
ATGCAGGCCCAGCCCGGCGCGCGGCCCTACGACACCGTCCGCGTCGTCCGCGCCGGCGTCTTCGAGATTTCGCTCGCCAG
CCGGCAGGGTCCGGGGCGCGAGAACAATGAGGACGCGGTCTTCAGCAATCCGGAGACCGGCGTTCATCTGGTGGCCGACG
GCGTCGGCGGCCTGCCCTATGGCGAGGTGGCGAGCTGGGAGATCGTGCAGGCCTGCACCGCCATCCATGCCGCGGACCTC
TCCTTCATGGATCGGCTGGAGTGGCTGGAGGATCGTCTCCTCGCCGCCAACCATACGCTCTATCAGGCGGGCATGACGGC
GCCGCAGGCCTTCACCATGGCCTCCACGGTGGTCGCCGCACAGGTGGAAGATGATCGTGCCGGGCTCTTCTGGGCCGGGG
ATTCCCGCGCCTACCTGCGCCACCACGGCCGCCTCTTGCAGCTCACCACGGACCATGTGGAACTGCGCGACCGGCGGCGC
CTCGTCACGCGCCTGGTGGGCGCGACGCCCGACCCCGAACTCGATTTCCGCATCGTGCAGATCGACCCCGGTGCGCGGCT
GCTGCTGTGCACGGATGGCATTTTCGACGCGGTGCCGCCGGAGGTGATCGGTGCGACGCTCGACCTCGAGCGACGCGATC
TGGCGACGGCGCTGCTGGAAGCCGCCGACTGCTATTCCGGGCGCGACGACGCCACCGCCATCGTCCTGCGCCATGTGGGA
GGCACCCCATGA

Upstream 100 bases:

>100_bases
CCTGCCGATGCCGGCGCATTCCTTGCCGCCTTCACCGCCGAACCGGAGAACCGCAATTCCCTCTTCTCCTTCTGGTCGGC
ACGCAAGAATGGCTGACGAC

Downstream 100 bases:

>100_bases
GCGAGGCCGATCCGTCTGCCCTGCCCTGCGCCGGCGACCATGAGGCGCTGTCCCGCCTCGAGGGGATCTGCCGCCAGATC
GCCAAGGGCGACTACGACAA

Product: serine/threonine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MQAQPGARPYDTVRVVRAGVFEISLASRQGPGRENNEDAVFSNPETGVHLVADGVGGLPYGEVASWEIVQACTAIHAADL
SFMDRLEWLEDRLLAANHTLYQAGMTAPQAFTMASTVVAAQVEDDRAGLFWAGDSRAYLRHHGRLLQLTTDHVELRDRRR
LVTRLVGATPDPELDFRIVQIDPGARLLLCTDGIFDAVPPEVIGATLDLERRDLATALLEAADCYSGRDDATAIVLRHVG
GTP

Sequences:

>Translated_243_residues
MQAQPGARPYDTVRVVRAGVFEISLASRQGPGRENNEDAVFSNPETGVHLVADGVGGLPYGEVASWEIVQACTAIHAADL
SFMDRLEWLEDRLLAANHTLYQAGMTAPQAFTMASTVVAAQVEDDRAGLFWAGDSRAYLRHHGRLLQLTTDHVELRDRRR
LVTRLVGATPDPELDFRIVQIDPGARLLLCTDGIFDAVPPEVIGATLDLERRDLATALLEAADCYSGRDDATAIVLRHVG
GTP
>Mature_243_residues
MQAQPGARPYDTVRVVRAGVFEISLASRQGPGRENNEDAVFSNPETGVHLVADGVGGLPYGEVASWEIVQACTAIHAADL
SFMDRLEWLEDRLLAANHTLYQAGMTAPQAFTMASTVVAAQVEDDRAGLFWAGDSRAYLRHHGRLLQLTTDHVELRDRRR
LVTRLVGATPDPELDFRIVQIDPGARLLLCTDGIFDAVPPEVIGATLDLERRDLATALLEAADCYSGRDDATAIVLRHVG
GTP

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26425; Mature: 26425

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAQPGARPYDTVRVVRAGVFEISLASRQGPGRENNEDAVFSNPETGVHLVADGVGGLPY
CCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCC
GEVASWEIVQACTAIHAADLSFMDRLEWLEDRLLAANHTLYQAGMTAPQAFTMASTVVAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHEEEE
QVEDDRAGLFWAGDSRAYLRHHGRLLQLTTDHVELRDRRRLVTRLVGATPDPELDFRIVQ
EECCCCCCEEEECCCCHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IDPGARLLLCTDGIFDAVPPEVIGATLDLERRDLATALLEAADCYSGRDDATAIVLRHVG
ECCCCEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEECCC
GTP
CCC
>Mature Secondary Structure
MQAQPGARPYDTVRVVRAGVFEISLASRQGPGRENNEDAVFSNPETGVHLVADGVGGLPY
CCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCC
GEVASWEIVQACTAIHAADLSFMDRLEWLEDRLLAANHTLYQAGMTAPQAFTMASTVVAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHEEEE
QVEDDRAGLFWAGDSRAYLRHHGRLLQLTTDHVELRDRRRLVTRLVGATPDPELDFRIVQ
EECCCCCCEEEECCCCHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IDPGARLLLCTDGIFDAVPPEVIGATLDLERRDLATALLEAADCYSGRDDATAIVLRHVG
ECCCCEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEECCC
GTP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]