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The map label for this gene is hflK [H]

Identifier: 158424193

GI number: 158424193

Start: 2894045

End: 2895175

Strand: Direct

Name: hflK [H]

Synonym: AZC_2569

Alternate gene names: 158424193

Gene position: 2894045-2895175 (Clockwise)

Preceding gene: 158424192

Following gene: 158424194

Centisome position: 53.9

GC content: 68.17

Gene sequence:

>1131_bases
ATGTCGTGGAAAAATCAGGGCGGTGGCCCCTGGGGAAATGGGCCGCGGGGGCCCTGGGGTCAGGGACCGAACAATTCCGG
ACCGACGCCTCCAGACATTGAAGACATCATCCGCCGCAGTCAGGACCGCCTGCGGCACATGCTCCCGGGCTCCATGGGCA
CCAAGGGCGCAATCCTTCTGGTCGCTCTGGTGGTGGCCGGCTGGCTCCTCTCCGGCTTCTACCGCGTCGAGCCCGACGAG
CAGGGCGTCGTCCTGCGCTTCGGCCGCTTCGTGCAGCTCACCCAGCCGGGCCTCAACTATCACCTGCCCTACCCGATCGA
GACCGTGCTGACCCCCAAGGTCACGCGCGTGAACCGCATCGACATCGGCATGCGCCTCGCCGAGGACACCCGACGCAACG
CCACCGTGCTGCGCGACGTTCCCGAGGAGAGCCTGATGCTCACCGGCGACGAGAACATCGTCGACGTGGATTTCGCCGTC
TTCTGGGTCATCAACAACGCCGAGCAGTATCTGTTCAACGTGCAGAACCCGGAGAGCACCATCAAGGCGGTGGCCGAGAG
CGCCATGCGCGAGGTGGTCGGCCGCAACAACATCCAGCCCATCCTCACCGGCGCCCGGCAGAACATCGAGACCGGCGTGC
AGGACCTGATGCAGCGGGTGCTCGACAGCTACAGCGCCGGCGTGAAGATCACGCAGGTCCAGCTCCAGAAGGTGGACCCG
CCGGCGCAGGTCATCGACGCCTTCCGCGACGTGCAGGCCGCCCGCGCGGACGCCGAGCGCGCCCAGAACGAGGCGCAGAC
CTACGCCAACCGCGTCGTGCCCGAGGCGCGAGGCGAAGCCGCCCGCATCGAAAACGGCGCCCAGGCCTACCGCGAGCGCA
CCGTGGTGGAAGCCCGCGGCCAGGCCGAGCGCTTCCTCAAGATCTACGATGAATATGTGAAGGCGAAGGACGTGACGCGC
GAGCGCATGTATCTGGAGACCATGGAACGTGTGCTCGGCGGCACCGACAAGGTGATCGTCGACCAGAACGCCAGCCGCAG
CGGCGGCGTGGTGCCCGTGCTGCCGCTCAACGAGCCGGCCCGCCGCGCCCCCGCCCCCACCGGCCCGCAGACCCAGGGAG
CCGCCCGATGA

Upstream 100 bases:

>100_bases
GGCGCGTCCATGGGGCGCGTGTGCCCGGACCGCGAAGCGGTGGCAGAGTGGTACAGGTCTGGACCGCCGCCATCGCGCGG
CGCTCCTACGGGAGTCGACG

Downstream 100 bases:

>100_bases
AAAACTCTTTCCTCGGCGGCGGCATCCTCGTCGTCTTCCTCATCGTGGTGATCGGCCTCTATTCCTCGGCCTTCACCGTG
ACCCAGAACCAGCAGGCGCT

Product: HflK protein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSWKNQGGGPWGNGPRGPWGQGPNNSGPTPPDIEDIIRRSQDRLRHMLPGSMGTKGAILLVALVVAGWLLSGFYRVEPDE
QGVVLRFGRFVQLTQPGLNYHLPYPIETVLTPKVTRVNRIDIGMRLAEDTRRNATVLRDVPEESLMLTGDENIVDVDFAV
FWVINNAEQYLFNVQNPESTIKAVAESAMREVVGRNNIQPILTGARQNIETGVQDLMQRVLDSYSAGVKITQVQLQKVDP
PAQVIDAFRDVQAARADAERAQNEAQTYANRVVPEARGEAARIENGAQAYRERTVVEARGQAERFLKIYDEYVKAKDVTR
ERMYLETMERVLGGTDKVIVDQNASRSGGVVPVLPLNEPARRAPAPTGPQTQGAAR

Sequences:

>Translated_376_residues
MSWKNQGGGPWGNGPRGPWGQGPNNSGPTPPDIEDIIRRSQDRLRHMLPGSMGTKGAILLVALVVAGWLLSGFYRVEPDE
QGVVLRFGRFVQLTQPGLNYHLPYPIETVLTPKVTRVNRIDIGMRLAEDTRRNATVLRDVPEESLMLTGDENIVDVDFAV
FWVINNAEQYLFNVQNPESTIKAVAESAMREVVGRNNIQPILTGARQNIETGVQDLMQRVLDSYSAGVKITQVQLQKVDP
PAQVIDAFRDVQAARADAERAQNEAQTYANRVVPEARGEAARIENGAQAYRERTVVEARGQAERFLKIYDEYVKAKDVTR
ERMYLETMERVLGGTDKVIVDQNASRSGGVVPVLPLNEPARRAPAPTGPQTQGAAR
>Mature_375_residues
SWKNQGGGPWGNGPRGPWGQGPNNSGPTPPDIEDIIRRSQDRLRHMLPGSMGTKGAILLVALVVAGWLLSGFYRVEPDEQ
GVVLRFGRFVQLTQPGLNYHLPYPIETVLTPKVTRVNRIDIGMRLAEDTRRNATVLRDVPEESLMLTGDENIVDVDFAVF
WVINNAEQYLFNVQNPESTIKAVAESAMREVVGRNNIQPILTGARQNIETGVQDLMQRVLDSYSAGVKITQVQLQKVDPP
AQVIDAFRDVQAARADAERAQNEAQTYANRVVPEARGEAARIENGAQAYRERTVVEARGQAERFLKIYDEYVKAKDVTRE
RMYLETMERVLGGTDKVIVDQNASRSGGVVPVLPLNEPARRAPAPTGPQTQGAAR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=399, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 41632; Mature: 41501

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKNQGGGPWGNGPRGPWGQGPNNSGPTPPDIEDIIRRSQDRLRHMLPGSMGTKGAILL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VALVVAGWLLSGFYRVEPDEQGVVLRFGRFVQLTQPGLNYHLPYPIETVLTPKVTRVNRI
HHHHHHHHHHHCCEEECCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHCCCCCCEEEEH
DIGMRLAEDTRRNATVLRDVPEESLMLTGDENIVDVDFAVFWVINNAEQYLFNVQNPEST
HHHHEHHHHHCCCCHHHHCCCCCCEEEECCCCEEEEEEEEEEEEECCHHHEEECCCHHHH
IKAVAESAMREVVGRNNIQPILTGARQNIETGVQDLMQRVLDSYSAGVKITQVQLQKVDP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCC
PAQVIDAFRDVQAARADAERAQNEAQTYANRVVPEARGEAARIENGAQAYRERTVVEARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QAERFLKIYDEYVKAKDVTRERMYLETMERVLGGTDKVIVDQNASRSGGVVPVLPLNEPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCHH
RRAPAPTGPQTQGAAR
HHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SWKNQGGGPWGNGPRGPWGQGPNNSGPTPPDIEDIIRRSQDRLRHMLPGSMGTKGAILL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VALVVAGWLLSGFYRVEPDEQGVVLRFGRFVQLTQPGLNYHLPYPIETVLTPKVTRVNRI
HHHHHHHHHHHCCEEECCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHCCCCCCEEEEH
DIGMRLAEDTRRNATVLRDVPEESLMLTGDENIVDVDFAVFWVINNAEQYLFNVQNPEST
HHHHEHHHHHCCCCHHHHCCCCCCEEEECCCCEEEEEEEEEEEEECCHHHEEECCCHHHH
IKAVAESAMREVVGRNNIQPILTGARQNIETGVQDLMQRVLDSYSAGVKITQVQLQKVDP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCC
PAQVIDAFRDVQAARADAERAQNEAQTYANRVVPEARGEAARIENGAQAYRERTVVEARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QAERFLKIYDEYVKAKDVTRERMYLETMERVLGGTDKVIVDQNASRSGGVVPVLPLNEPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCHH
RRAPAPTGPQTQGAAR
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]