Click here to switch to the map view.

The map label for this gene is ybhD [H]

Identifier: 158424115

GI number: 158424115

Start: 2826487

End: 2827428

Strand: Reverse

Name: ybhD [H]

Synonym: AZC_2491

Alternate gene names: 158424115

Gene position: 2827428-2826487 (Counterclockwise)

Preceding gene: 158424132

Following gene: 158424114

Centisome position: 52.65

GC content: 70.49

Gene sequence:

>942_bases
ATGTCGATGAATATGAACTTGCGCCAGCTACGGGCCTTCGTGGCGGTGGCCCAGACCGGCAGCTTCAGCCGCGCCGCGCG
CCTCCTCGGCCTCTCCCAGTCGGCTCTGAGTCAGGCCGTCCAGCAACTGGAAGCCGACCTCGGCGTGCGGCTTCTGGACC
GCACCACCCGCAGCGTGCAGCTGAGCGCCATCGGGCGTGAATTCCTCCCCGGTGTGCAGCGCGTGCTGGCGGACCTTGAT
CACCAGTTGCAGGATCTCAGGGACCTCAAGGAGCACCGGCGGGGCCACGTGACAGTCACCTGCGTGCCCTCCGTCGCCCT
GCGCCTGCTGCCGCAGGTGCTGGCGCAGTTTCAGGAGGCCCATCCCATGGTGAGCGTCGCCGTGCGCGAGGCGCCGCGCC
ACCAGATCATCACCGCTCTGCGCAGCGGTGACGCGGAACTCGGCGTTGCCAACGTGCCGGGCGATGATCCGGATCTCGAC
AGCACCTTCCTGCTCACCGACAGCTTCGCCCTCGTGATGCGGCGGGACCATCCACTGGCCGCCCATGAGAGCGTGACATG
GGAGGAGGCCGGGCAGGCGGGCCTCATCGCCATGGCGCCGGGCACGGGCATCCGGCTGGAAATGGAGCGCGGCCTGCCCG
CGCCCGCCGTGCCTCACCACGAGGCGGAGCATCCGGCGACATTGCTGGCCATGGTGGAGGCAGGCGTCGGGGTGGCGCCG
CTTCCGGGCTTGGCCTGGCCCCGTCCGGATCACGCCGGGCTCACCTTCCGTCCATTGGTGGAGCCGCGCGTGGAGCGGCA
ACTGTTCCTCATCAAGCGGGCGGGCCGCGATCTCACGCCCGCCGGCCGCGCCCTGCACCGGGCGATCCTGGCCGGCGTGG
CGAAGGAGGATTTTTCAGGTGCCGCCGTTCCGCGTGGCGGACGCCGCCCGCGTGGACAGTGA

Upstream 100 bases:

>100_bases
GGCGGCGTGAGGGCCGCTGCACATTCATTGTTCACGGTGAAAATGGTGGCATCCGCTCAGCTTATTAACAAGCCGGGAAA
AACCAATATATTCATAAGAT

Downstream 100 bases:

>100_bases
CGCAAGGGACGGTCTAATCATCGGGAAAGGGACCATCAGCGGGGATCAGTGATGACGCGGCCGGACATCCTTGTGGTCAA
TCCCAATTCCAATGCGGTGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSMNMNLRQLRAFVAVAQTGSFSRAARLLGLSQSALSQAVQQLEADLGVRLLDRTTRSVQLSAIGREFLPGVQRVLADLD
HQLQDLRDLKEHRRGHVTVTCVPSVALRLLPQVLAQFQEAHPMVSVAVREAPRHQIITALRSGDAELGVANVPGDDPDLD
STFLLTDSFALVMRRDHPLAAHESVTWEEAGQAGLIAMAPGTGIRLEMERGLPAPAVPHHEAEHPATLLAMVEAGVGVAP
LPGLAWPRPDHAGLTFRPLVEPRVERQLFLIKRAGRDLTPAGRALHRAILAGVAKEDFSGAAVPRGGRRPRGQ

Sequences:

>Translated_313_residues
MSMNMNLRQLRAFVAVAQTGSFSRAARLLGLSQSALSQAVQQLEADLGVRLLDRTTRSVQLSAIGREFLPGVQRVLADLD
HQLQDLRDLKEHRRGHVTVTCVPSVALRLLPQVLAQFQEAHPMVSVAVREAPRHQIITALRSGDAELGVANVPGDDPDLD
STFLLTDSFALVMRRDHPLAAHESVTWEEAGQAGLIAMAPGTGIRLEMERGLPAPAVPHHEAEHPATLLAMVEAGVGVAP
LPGLAWPRPDHAGLTFRPLVEPRVERQLFLIKRAGRDLTPAGRALHRAILAGVAKEDFSGAAVPRGGRRPRGQ
>Mature_312_residues
SMNMNLRQLRAFVAVAQTGSFSRAARLLGLSQSALSQAVQQLEADLGVRLLDRTTRSVQLSAIGREFLPGVQRVLADLDH
QLQDLRDLKEHRRGHVTVTCVPSVALRLLPQVLAQFQEAHPMVSVAVREAPRHQIITALRSGDAELGVANVPGDDPDLDS
TFLLTDSFALVMRRDHPLAAHESVTWEEAGQAGLIAMAPGTGIRLEMERGLPAPAVPHHEAEHPATLLAMVEAGVGVAPL
PGLAWPRPDHAGLTFRPLVEPRVERQLFLIKRAGRDLTPAGRALHRAILAGVAKEDFSGAAVPRGGRRPRGQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=298, Percent_Identity=33.2214765100671, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788748, Length=286, Percent_Identity=36.7132867132867, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=30.5555555555556, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=29.9651567944251, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=28.9115646258503, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787601, Length=187, Percent_Identity=31.0160427807487, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87081904, Length=209, Percent_Identity=32.5358851674641, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788887, Length=263, Percent_Identity=29.277566539924, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367136, Length=282, Percent_Identity=26.9503546099291, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789204, Length=251, Percent_Identity=27.4900398406374, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787589, Length=118, Percent_Identity=39.8305084745763, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786401, Length=126, Percent_Identity=34.9206349206349, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788481, Length=203, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789639, Length=120, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=280, Percent_Identity=25.3571428571429, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=26.5625, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=28.2258064516129, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786713, Length=181, Percent_Identity=32.0441988950276, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082132, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786508, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787128, Length=124, Percent_Identity=31.4516129032258, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=184, Percent_Identity=27.7173913043478, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=287, Percent_Identity=24.7386759581882, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790011, Length=166, Percent_Identity=24.0963855421687, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788706, Length=122, Percent_Identity=31.1475409836066, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33843; Mature: 33712

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNMNLRQLRAFVAVAQTGSFSRAARLLGLSQSALSQAVQQLEADLGVRLLDRTTRSVQ
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHCCHHEE
LSAIGREFLPGVQRVLADLDHQLQDLRDLKEHRRGHVTVTCVPSVALRLLPQVLAQFQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHH
HPMVSVAVREAPRHQIITALRSGDAELGVANVPGDDPDLDSTFLLTDSFALVMRRDHPLA
CCHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEECCEEEEEECCCCCC
AHESVTWEEAGQAGLIAMAPGTGIRLEMERGLPAPAVPHHEAEHPATLLAMVEAGVGVAP
CCCCCCHHHCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
LPGLAWPRPDHAGLTFRPLVEPRVERQLFLIKRAGRDLTPAGRALHRAILAGVAKEDFSG
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
AAVPRGGRRPRGQ
CCCCCCCCCCCCC
>Mature Secondary Structure 
SMNMNLRQLRAFVAVAQTGSFSRAARLLGLSQSALSQAVQQLEADLGVRLLDRTTRSVQ
CCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHCCHHEE
LSAIGREFLPGVQRVLADLDHQLQDLRDLKEHRRGHVTVTCVPSVALRLLPQVLAQFQEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHH
HPMVSVAVREAPRHQIITALRSGDAELGVANVPGDDPDLDSTFLLTDSFALVMRRDHPLA
CCHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEECCEEEEEECCCCCC
AHESVTWEEAGQAGLIAMAPGTGIRLEMERGLPAPAVPHHEAEHPATLLAMVEAGVGVAP
CCCCCCHHHCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
LPGLAWPRPDHAGLTFRPLVEPRVERQLFLIKRAGRDLTPAGRALHRAILAGVAKEDFSG
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
AAVPRGGRRPRGQ
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]