Click here to switch to the map view.

The map label for this gene is ackA [H]

Identifier: 158424045

GI number: 158424045

Start: 2750615

End: 2751808

Strand: Direct

Name: ackA [H]

Synonym: AZC_2421

Alternate gene names: 158424045

Gene position: 2750615-2751808 (Clockwise)

Preceding gene: 158424044

Following gene: 158424051

Centisome position: 51.22

GC content: 68.34

Gene sequence:

>1194_bases
ATGAGCCGACACATCCTGCTCACCTTCAATCCCGGCTCCTCCACGATCAAGCTGGGCCTCTTCGATGCGAGCCCGGAGGC
CGTCCGCCGCATCGGCAAGGGCGTCATCGACCTGCGGCACAAGCCGCTGGTGCTGAACATCGTGGAAGGCCGCAGCACGG
CCGAGATCCCGCTGAAGGCCCAGGTGACCGATGACCTGCATGAGGTCATCGAGGAAACGCTCTCCTGGCTTGCGCACCAT
TTCGAGGTGGCCGAGCTGACGGCCGTGGGCCATCGCGTGGTTCATGGCGGCGACCGGTTCAGCGGGCCGGTGCGCATCAC
GCCGGAGGTGGCGGGCGCCATCGCCGATGTCGTGCCGCTCGCCCCCCTTCACCAGCCCCACAGCGTGCGGCTCATCAAGG
CCATCAGCCATCTGCGGCCCGACCTGCCGCAGGTCGCCTCCTTCGACACCGCCTTCCACCGGACCCAGCCGGATGTGGCG
CGCCGTTTCGCCATTCCCCGCGCGCTGTTCGACGCCGGCATCAAGCGCTACGGCTTCCACGGTTTGTCCTACAAATACAT
CGCCTCGGCCCTCGCCCGCGTCGCGCCGGAGGCGGCGAAAGGTCATGTGGTGGCGGCGCATCTCGGCAGCGGAGCGAGCC
TCTGCGTGCTGAAGGGCGGCCTCAGCCTCGACAGCAGCATGGGCTTTTCCACCCTCGACGGCATTCCCATGGCGACCCGC
TGCGGCGCGCTCGACCCCGGCGTCCTGCTGCATCTGCTGACGCAGGGCGGACAGAGCGTCGCCGAGGTGCAGGACATGGT
CTATTACCGCTCGGGCCTCCTCGGCCTGTCCGGCATCAGCGCGGACAGCCGCGATCTCATCGGCAACCCGGCCCCCGAGG
CACGCGAGGCGCTGGCGGTCTTCGCCTTCCGCATTGCCCGCGAGGCCACCGCGCTGGCGACCAGCGGCGGCGGGCTCGAT
ACGCTGGTCTTCACTGCCGGCATTGGCGAACATCAGCCGGAGGTCCGCTCCGCCGTCTGCGCGCATCTGACCTGGCTCGG
CGTGAAGCTCGATCCGGCCGCCAATGCCGCCAATGCGACCCGCATCAGCACGCCGGACAGCCGCGTCGGAATATTCGTCA
TCCCGACCGATGAGGAACAGGTCATCGCCGACGAAGCCTTCGGAGTCCTTCACACGGGAGAGGCGTCACACTGA

Upstream 100 bases:

>100_bases
TCATCCTCACCAGCCGGGCGGATTCGCTGCGGGTACGCCTCGCCTCGGTGGCGCTCGCCAAGCTGTCCATCGCCGGTGGC
CATGCGGTGGCGGTGCCCGC

Downstream 100 bases:

>100_bases
CCGCCGCTGCGCAAGCGGGCCGACCTCGGGCTACTCGATGTTCGGCTCGTAGTCGGCAAGCGCGCGGATCACCACAGGGT
TGGCCGCATAGGATTTGCGC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSRHILLTFNPGSSTIKLGLFDASPEAVRRIGKGVIDLRHKPLVLNIVEGRSTAEIPLKAQVTDDLHEVIEETLSWLAHH
FEVAELTAVGHRVVHGGDRFSGPVRITPEVAGAIADVVPLAPLHQPHSVRLIKAISHLRPDLPQVASFDTAFHRTQPDVA
RRFAIPRALFDAGIKRYGFHGLSYKYIASALARVAPEAAKGHVVAAHLGSGASLCVLKGGLSLDSSMGFSTLDGIPMATR
CGALDPGVLLHLLTQGGQSVAEVQDMVYYRSGLLGLSGISADSRDLIGNPAPEAREALAVFAFRIAREATALATSGGGLD
TLVFTAGIGEHQPEVRSAVCAHLTWLGVKLDPAANAANATRISTPDSRVGIFVIPTDEEQVIADEAFGVLHTGEASH

Sequences:

>Translated_397_residues
MSRHILLTFNPGSSTIKLGLFDASPEAVRRIGKGVIDLRHKPLVLNIVEGRSTAEIPLKAQVTDDLHEVIEETLSWLAHH
FEVAELTAVGHRVVHGGDRFSGPVRITPEVAGAIADVVPLAPLHQPHSVRLIKAISHLRPDLPQVASFDTAFHRTQPDVA
RRFAIPRALFDAGIKRYGFHGLSYKYIASALARVAPEAAKGHVVAAHLGSGASLCVLKGGLSLDSSMGFSTLDGIPMATR
CGALDPGVLLHLLTQGGQSVAEVQDMVYYRSGLLGLSGISADSRDLIGNPAPEAREALAVFAFRIAREATALATSGGGLD
TLVFTAGIGEHQPEVRSAVCAHLTWLGVKLDPAANAANATRISTPDSRVGIFVIPTDEEQVIADEAFGVLHTGEASH
>Mature_396_residues
SRHILLTFNPGSSTIKLGLFDASPEAVRRIGKGVIDLRHKPLVLNIVEGRSTAEIPLKAQVTDDLHEVIEETLSWLAHHF
EVAELTAVGHRVVHGGDRFSGPVRITPEVAGAIADVVPLAPLHQPHSVRLIKAISHLRPDLPQVASFDTAFHRTQPDVAR
RFAIPRALFDAGIKRYGFHGLSYKYIASALARVAPEAAKGHVVAAHLGSGASLCVLKGGLSLDSSMGFSTLDGIPMATRC
GALDPGVLLHLLTQGGQSVAEVQDMVYYRSGLLGLSGISADSRDLIGNPAPEAREALAVFAFRIAREATALATSGGGLDT
LVFTAGIGEHQPEVRSAVCAHLTWLGVKLDPAANAANATRISTPDSRVGIFVIPTDEEQVIADEAFGVLHTGEASH

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=407, Percent_Identity=35.8722358722359, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1788633, Length=402, Percent_Identity=34.0796019900498, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 42037; Mature: 41905

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHILLTFNPGSSTIKLGLFDASPEAVRRIGKGVIDLRHKPLVLNIVEGRSTAEIPLKA
CCCEEEEEECCCCCEEEEEEECCCHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCEEE
QVTDDLHEVIEETLSWLAHHFEVAELTAVGHRVVHGGDRFSGPVRITPEVAGAIADVVPL
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECHHHHHHHHHHHCC
APLHQPHSVRLIKAISHLRPDLPQVASFDTAFHRTQPDVARRFAIPRALFDAGIKRYGFH
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLSYKYIASALARVAPEAAKGHVVAAHLGSGASLCVLKGGLSLDSSMGFSTLDGIPMATR
CCCHHHHHHHHHHHCCHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCHHHCCCCCHHH
CGALDPGVLLHLLTQGGQSVAEVQDMVYYRSGLLGLSGISADSRDLIGNPAPEAREALAV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHH
FAFRIAREATALATSGGGLDTLVFTAGIGEHQPEVRSAVCAHLTWLGVKLDPAANAANAT
HHHHHHHHHHHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCC
RISTPDSRVGIFVIPTDEEQVIADEAFGVLHTGEASH
EECCCCCCEEEEEEECCCCHHHHHHHCCEEECCCCCC
>Mature Secondary Structure 
SRHILLTFNPGSSTIKLGLFDASPEAVRRIGKGVIDLRHKPLVLNIVEGRSTAEIPLKA
CCEEEEEECCCCCEEEEEEECCCHHHHHHHCCCCEECCCCCEEEEEECCCCCCCCCEEE
QVTDDLHEVIEETLSWLAHHFEVAELTAVGHRVVHGGDRFSGPVRITPEVAGAIADVVPL
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECHHHHHHHHHHHCC
APLHQPHSVRLIKAISHLRPDLPQVASFDTAFHRTQPDVARRFAIPRALFDAGIKRYGFH
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLSYKYIASALARVAPEAAKGHVVAAHLGSGASLCVLKGGLSLDSSMGFSTLDGIPMATR
CCCHHHHHHHHHHHCCHHHCCCEEEEECCCCCEEEEEECCCCCCCCCCCHHHCCCCCHHH
CGALDPGVLLHLLTQGGQSVAEVQDMVYYRSGLLGLSGISADSRDLIGNPAPEAREALAV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHH
FAFRIAREATALATSGGGLDTLVFTAGIGEHQPEVRSAVCAHLTWLGVKLDPAANAANAT
HHHHHHHHHHHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCC
RISTPDSRVGIFVIPTDEEQVIADEAFGVLHTGEASH
EECCCCCCEEEEEEECCCCHHHHHHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA