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The map label for this gene is yogA [H]

Identifier: 158424032

GI number: 158424032

Start: 2735077

End: 2736099

Strand: Direct

Name: yogA [H]

Synonym: AZC_2408

Alternate gene names: 158424032

Gene position: 2735077-2736099 (Clockwise)

Preceding gene: 158424031

Following gene: 158424033

Centisome position: 50.93

GC content: 66.67

Gene sequence:

>1023_bases
ATGCGCGCCCTTCAACTCGTTTCCGACCGTTCGCTCCAGCTCGTCGACCTGCCCGAGCCCGACGCCCCCGGCGCCGGCGA
GGTGCAGGTGCGCGTGAAGGCGCTCGCCCTCAACCACATCGACGTGTGGGGCTGGCGCGGCATGGCCTTTGCCAAGCGCA
AGATGCCGCTGGTGGTGGGTGCGGAAGCGGCCGGCGAGATCGTCGCGCTGGGTGCCGACGTGCGCGGCCTGAAGGTCGGC
CAGACCGTCTCCATGTATGGCGCCCTGACCTGCGGCCACTGCTCCAACTGCCTCAAGGGCCGCGACAATCTCTGCGAGAA
CGTGGGCGGCGTGCTCGGCTTCCACGTGGACGGCTTCGCCCGCGACGTGCTGAACATGCCCGAGCGCCTCGTCATTCCCG
CCCCCGAGGGCGTGACCTTCGAGGAAGCGGCCTGCGCCGGCATCACGTTCTCCACCGTCGAGCACATGCTGTTCGACAAT
GCCAAGCTTGAAAAGGGCGAGACCGTCCTCGTGCATGCCGGCGGCTCGGGCATCGGCTCGGCGGCCATACGCCTTGCCAA
GGACGTGGGCGCCACCGTCATCACCACCGTGGGCGATGACGAGAAGGCCGCCAAGGCCGAGGCTCTGGGCGCCGATCACG
TCATCAACTACAAGACCGAGCGCTTCGAGCACATGGTCCGCAAGATCACCAAGAAGGTGGGCGTGGACGTGGTGTTCGAG
CATGTGGGCGTGGACACCTGGCAGGGCTCGCTGCTCTCCATGAAGCCCGGCGGCCGCCTTGTCACCTGCGGCTCCACCTC
CGGCGTCTCGACGCAGATGAACCTGATGCAGCTCTTCCAGCGCCAGTACAAGATCTTCGGCTCCTTCGGCGCGACCATCC
GGAACGTGGCCGACGGCCTCGAGAAGATGGGCCGGGGCGTGAAGCCGGTGATCGACACCGTGGTGCCGCTCGCGGATTTC
AATGCCGGCCTCGAGCGACTGGAAAGCCGCAAGGTGTTCGGCAAGATCCTCGTAAAGTTCTGA

Upstream 100 bases:

>100_bases
TCTCGCCCGGCGCGAGCTATATCACCGGCGCCGTGATCCCGGTGGACGGCGGCCTCACCGCCACGCTCGCCGCCCACCGC
TGAACCTCGTCAGGACCAAC

Downstream 100 bases:

>100_bases
GCCGATCCGCCGGGAGACCAGCGTGGGTCACGCAAAGCAGCTGTGGCGCCGGTTTGCGCGCCGCATGCAGCCGGCTTTCG
ATACGTTCGTAGCCGGCTAT

Product: zinc-containing alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRALQLVSDRSLQLVDLPEPDAPGAGEVQVRVKALALNHIDVWGWRGMAFAKRKMPLVVGAEAAGEIVALGADVRGLKVG
QTVSMYGALTCGHCSNCLKGRDNLCENVGGVLGFHVDGFARDVLNMPERLVIPAPEGVTFEEAACAGITFSTVEHMLFDN
AKLEKGETVLVHAGGSGIGSAAIRLAKDVGATVITTVGDDEKAAKAEALGADHVINYKTERFEHMVRKITKKVGVDVVFE
HVGVDTWQGSLLSMKPGGRLVTCGSTSGVSTQMNLMQLFQRQYKIFGSFGATIRNVADGLEKMGRGVKPVIDTVVPLADF
NAGLERLESRKVFGKILVKF

Sequences:

>Translated_340_residues
MRALQLVSDRSLQLVDLPEPDAPGAGEVQVRVKALALNHIDVWGWRGMAFAKRKMPLVVGAEAAGEIVALGADVRGLKVG
QTVSMYGALTCGHCSNCLKGRDNLCENVGGVLGFHVDGFARDVLNMPERLVIPAPEGVTFEEAACAGITFSTVEHMLFDN
AKLEKGETVLVHAGGSGIGSAAIRLAKDVGATVITTVGDDEKAAKAEALGADHVINYKTERFEHMVRKITKKVGVDVVFE
HVGVDTWQGSLLSMKPGGRLVTCGSTSGVSTQMNLMQLFQRQYKIFGSFGATIRNVADGLEKMGRGVKPVIDTVVPLADF
NAGLERLESRKVFGKILVKF
>Mature_340_residues
MRALQLVSDRSLQLVDLPEPDAPGAGEVQVRVKALALNHIDVWGWRGMAFAKRKMPLVVGAEAAGEIVALGADVRGLKVG
QTVSMYGALTCGHCSNCLKGRDNLCENVGGVLGFHVDGFARDVLNMPERLVIPAPEGVTFEEAACAGITFSTVEHMLFDN
AKLEKGETVLVHAGGSGIGSAAIRLAKDVGATVITTVGDDEKAAKAEALGADHVINYKTERFEHMVRKITKKVGVDVVFE
HVGVDTWQGSLLSMKPGGRLVTCGSTSGVSTQMNLMQLFQRQYKIFGSFGATIRNVADGLEKMGRGVKPVIDTVVPLADF
NAGLERLESRKVFGKILVKF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=28.3185840707965, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=28.3185840707965, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI18379349, Length=341, Percent_Identity=27.5659824046921, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI24308257, Length=352, Percent_Identity=25.8522727272727, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI194239674, Length=302, Percent_Identity=23.5099337748344, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI13236495, Length=302, Percent_Identity=23.5099337748344, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI28557745, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41872631, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI156627571, Length=343, Percent_Identity=27.6967930029155, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI34577061, Length=348, Percent_Identity=26.7241379310345, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4501929, Length=349, Percent_Identity=27.5071633237822, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226059159, Length=142, Percent_Identity=33.8028169014084, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226059133, Length=142, Percent_Identity=33.8028169014084, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226056130, Length=142, Percent_Identity=33.8028169014084, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4501933, Length=348, Percent_Identity=26.4367816091954, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=270, Percent_Identity=31.4814814814815, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790045, Length=352, Percent_Identity=28.125, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788073, Length=289, Percent_Identity=29.757785467128, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787863, Length=219, Percent_Identity=32.4200913242009, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI226510992, Length=158, Percent_Identity=34.1772151898734, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082125, Length=305, Percent_Identity=29.1803278688525, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082401, Length=329, Percent_Identity=24.6200607902736, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081918, Length=321, Percent_Identity=25.8566978193146, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788075, Length=343, Percent_Identity=24.7813411078717, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=265, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562878, Length=215, Percent_Identity=28.8372093023256, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507255, Length=291, Percent_Identity=26.4604810996564, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=335, Percent_Identity=23.8805970149254, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562584, Length=335, Percent_Identity=22.9850746268657, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562582, Length=334, Percent_Identity=23.3532934131737, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323961, Length=336, Percent_Identity=24.702380952381, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=337, Percent_Identity=25.8160237388724, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=336, Percent_Identity=25, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=24.6987951807229, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=341, Percent_Identity=25.5131964809384, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=25.748502994012, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319955, Length=334, Percent_Identity=25.4491017964072, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=249, Percent_Identity=28.1124497991968, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920632, Length=229, Percent_Identity=29.6943231441048, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221330659, Length=229, Percent_Identity=29.6943231441048, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24581345, Length=227, Percent_Identity=26.431718061674, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36318; Mature: 36318

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALQLVSDRSLQLVDLPEPDAPGAGEVQVRVKALALNHIDVWGWRGMAFAKRKMPLVVG
CCCHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHCCCEEEE
AEAAGEIVALGADVRGLKVGQTVSMYGALTCGHCSNCLKGRDNLCENVGGVLGFHVDGFA
CCCCCCEEEECCCCCCEECCCEEHHHHCEEHHHHHHHHCCHHHHHHHHCCEEEEEHHHHH
RDVLNMPERLVIPAPEGVTFEEAACAGITFSTVEHMLFDNAKLEKGETVLVHAGGSGIGS
HHHHCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIRLAKDVGATVITTVGDDEKAAKAEALGADHVINYKTERFEHMVRKITKKVGVDVVFE
HHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHCHHHHHH
HVGVDTWQGSLLSMKPGGRLVTCGSTSGVSTQMNLMQLFQRQYKIFGSFGATIRNVADGL
HCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMGRGVKPVIDTVVPLADFNAGLERLESRKVFGKILVKF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRALQLVSDRSLQLVDLPEPDAPGAGEVQVRVKALALNHIDVWGWRGMAFAKRKMPLVVG
CCCHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHCCCEEEE
AEAAGEIVALGADVRGLKVGQTVSMYGALTCGHCSNCLKGRDNLCENVGGVLGFHVDGFA
CCCCCCEEEECCCCCCEECCCEEHHHHCEEHHHHHHHHCCHHHHHHHHCCEEEEEHHHHH
RDVLNMPERLVIPAPEGVTFEEAACAGITFSTVEHMLFDNAKLEKGETVLVHAGGSGIGS
HHHHCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIRLAKDVGATVITTVGDDEKAAKAEALGADHVINYKTERFEHMVRKITKKVGVDVVFE
HHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHCHHHHHH
HVGVDTWQGSLLSMKPGGRLVTCGSTSGVSTQMNLMQLFQRQYKIFGSFGATIRNVADGL
HCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMGRGVKPVIDTVVPLADFNAGLERLESRKVFGKILVKF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]