Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 158424002

GI number: 158424002

Start: 2704730

End: 2705707

Strand: Direct

Name: ubiA [H]

Synonym: AZC_2378

Alternate gene names: 158424002

Gene position: 2704730-2705707 (Clockwise)

Preceding gene: 158424001

Following gene: 158424003

Centisome position: 50.37

GC content: 68.81

Gene sequence:

>978_bases
GTGAGCGGAGACCTGGGAGAGGCGGCCCGCGCGCCGGAACTGGCCGCGGTCGCCGACGCGCCGTCCGGCAATTGGGTGGA
CCGGCATGCGCCGGCGGCCCTGCGTCCCTATCTGCGGCTGGCCCGCCTCGACCGGCCCATCGGCAGTTGGCTCCTGCTCA
TGCCGTGCTGGTGGTCGACAGCGCTCGCCGCCGGTGCCGCGCACCAGCCCTATCCCGATCCGAAGCTGCTGATTCTGTTC
GCCATCGGTGCGGTCGCCATGCGCGGCGCCGGCTGCACCTGGAACGACATCCTCGACCGCAAGATCGACCGCATGGTCGC
GCGCACCCAGAACCGCCCTGTCGCCAGCGGCGCGGTCAGCGTGCCGGCGGCCATGGCGTTCCTGGTGTTCCAGTGCCTCG
TCGGCCTCGCGGTGCTGCTGTCCCTGCCCCGCTTCGCCGTCATCACCGGCATCGCCTCCCTTGGTGTCGTCGCCATCTAT
CCGCTGATGAAGCGCATCACCTCGGTGCCGCAGGCGGTGCTGGGCATCGCCTTCTCCTGGGGCGCCCTGATGGGCTGGGC
GAGCGTCTTCCGCAGCATCGACGATCCCGCGCTTCTGCTCTTCGCGGGTTCGGTGTGCTGGGTGTTCGCCTATGACACCA
TCTATGCCCATCAGGATCGCGAGGACGACGCCATCGTGGGCGTGCGCTCGACGGCATTGCTGTTCGGCCAGTCGAGCTGG
GTGGCGCTGGCGCTGAGCTACACGGCCACCGTCATCTTCTTCGCGCTGGCGCTCATGGAGACGCCGAGCGGCTTCTTCGC
CTGGGCGGGGCTCGTGGCTTTCGCGGCCCATCTCTTCAATCAGGTCCGTCGGCTCGATATCGACGATCCGGACCTGTGCC
TTGCGCTCTTCAAGTCCAACCGCGACGCCGGCCTTCTCTTCTTCGTCGGCCTGTCCCTGGACGTGGTGGCGCAGCACCTG
TCCGCCCTTTGGCCGTGA

Upstream 100 bases:

>100_bases
GCTCTGGGTGTCACCACCGGCTATGTGCCCGGCGAGAGCAACGGCCGCGGCGGTGTGTTCGACACGCTGACCGGCAACGC
CCTCTCCAAGTGACCAGAAC

Downstream 100 bases:

>100_bases
GTGCGCGCTCGGCGGGAACGGGCCTCAACTTTCTCCGGAGTGAACGCAAGTCGTCTTGCCACGGACATGCGAGGCGCTTA
AGGGCAGCCCCATGAAGTCG

Product: 4-hydroxybenzoate polyprenyl transferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSGDLGEAARAPELAAVADAPSGNWVDRHAPAALRPYLRLARLDRPIGSWLLLMPCWWSTALAAGAAHQPYPDPKLLILF
AIGAVAMRGAGCTWNDILDRKIDRMVARTQNRPVASGAVSVPAAMAFLVFQCLVGLAVLLSLPRFAVITGIASLGVVAIY
PLMKRITSVPQAVLGIAFSWGALMGWASVFRSIDDPALLLFAGSVCWVFAYDTIYAHQDREDDAIVGVRSTALLFGQSSW
VALALSYTATVIFFALALMETPSGFFAWAGLVAFAAHLFNQVRRLDIDDPDLCLALFKSNRDAGLLFFVGLSLDVVAQHL
SALWP

Sequences:

>Translated_325_residues
MSGDLGEAARAPELAAVADAPSGNWVDRHAPAALRPYLRLARLDRPIGSWLLLMPCWWSTALAAGAAHQPYPDPKLLILF
AIGAVAMRGAGCTWNDILDRKIDRMVARTQNRPVASGAVSVPAAMAFLVFQCLVGLAVLLSLPRFAVITGIASLGVVAIY
PLMKRITSVPQAVLGIAFSWGALMGWASVFRSIDDPALLLFAGSVCWVFAYDTIYAHQDREDDAIVGVRSTALLFGQSSW
VALALSYTATVIFFALALMETPSGFFAWAGLVAFAAHLFNQVRRLDIDDPDLCLALFKSNRDAGLLFFVGLSLDVVAQHL
SALWP
>Mature_324_residues
SGDLGEAARAPELAAVADAPSGNWVDRHAPAALRPYLRLARLDRPIGSWLLLMPCWWSTALAAGAAHQPYPDPKLLILFA
IGAVAMRGAGCTWNDILDRKIDRMVARTQNRPVASGAVSVPAAMAFLVFQCLVGLAVLLSLPRFAVITGIASLGVVAIYP
LMKRITSVPQAVLGIAFSWGALMGWASVFRSIDDPALLLFAGSVCWVFAYDTIYAHQDREDDAIVGVRSTALLFGQSSWV
ALALSYTATVIFFALALMETPSGFFAWAGLVAFAAHLFNQVRRLDIDDPDLCLALFKSNRDAGLLFFVGLSLDVVAQHLS
ALWP

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=291, Percent_Identity=46.7353951890034, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=36.6197183098592, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17553718, Length=283, Percent_Identity=39.9293286219081, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI32565247, Length=283, Percent_Identity=38.5159010600707, Blast_Score=173, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17553720, Length=190, Percent_Identity=41.5789473684211, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32565245, Length=147, Percent_Identity=44.2176870748299, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=154, Percent_Identity=42.2077922077922, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=317, Percent_Identity=39.1167192429022, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355567, Length=313, Percent_Identity=42.4920127795527, Blast_Score=234, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34987; Mature: 34856

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDLGEAARAPELAAVADAPSGNWVDRHAPAALRPYLRLARLDRPIGSWLLLMPCWWST
CCCCCCCHHCCCCHHEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALAAGAAHQPYPDPKLLILFAIGAVAMRGAGCTWNDILDRKIDRMVARTQNRPVASGAVS
HHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
VPAAMAFLVFQCLVGLAVLLSLPRFAVITGIASLGVVAIYPLMKRITSVPQAVLGIAFSW
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALMGWASVFRSIDDPALLLFAGSVCWVFAYDTIYAHQDREDDAIVGVRSTALLFGQSSW
HHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHEECCCCH
VALALSYTATVIFFALALMETPSGFFAWAGLVAFAAHLFNQVRRLDIDDPDLCLALFKSN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RDAGLLFFVGLSLDVVAQHLSALWP
CCCCEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SGDLGEAARAPELAAVADAPSGNWVDRHAPAALRPYLRLARLDRPIGSWLLLMPCWWST
CCCCCCHHCCCCHHEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALAAGAAHQPYPDPKLLILFAIGAVAMRGAGCTWNDILDRKIDRMVARTQNRPVASGAVS
HHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
VPAAMAFLVFQCLVGLAVLLSLPRFAVITGIASLGVVAIYPLMKRITSVPQAVLGIAFSW
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALMGWASVFRSIDDPALLLFAGSVCWVFAYDTIYAHQDREDDAIVGVRSTALLFGQSSW
HHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHEECCCCH
VALALSYTATVIFFALALMETPSGFFAWAGLVAFAAHLFNQVRRLDIDDPDLCLALFKSN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RDAGLLFFVGLSLDVVAQHLSALWP
CCCCEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA