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The map label for this gene is rpiA [H]

Identifier: 158423982

GI number: 158423982

Start: 2686759

End: 2687637

Strand: Reverse

Name: rpiA [H]

Synonym: AZC_2358

Alternate gene names: 158423982

Gene position: 2687637-2686759 (Counterclockwise)

Preceding gene: 158423985

Following gene: 158423981

Centisome position: 50.05

GC content: 69.06

Gene sequence:

>879_bases
TTGCCTCCTTGTCGCAGGTTCGGCCGCACCTTCAAGGGCGGCGTTTGCGGGACGGCACGGGTGGCCGGTGCGCCGCTTTG
CCTGTTCAAGCCAGGCGGCAGAGGGACGCGAAGATGCGCCAGCCGCTTGAGGTTCGCGCCGTTCGCGGCTAGGCAACCGG
CGAACCGCTGGAGCACAGACATGGCCGACGCCGAAGAGCTGAAACGCGCCGCCGCCGCCAAGGCGCTCGAATACGTGACC
GACGGCATGCGCCTCGGCCTCGGCACGGGCTCCACCGCCAAGCATTTCGTGGCGCTGCTCGCCGAGCGGGTCGCCGCCGG
CCTCAAGGTGACGGGCGTGCCGACCTCCGAGCAGACCAAGGCGCAGGCGCTTTCCCTCGGCGTGCCGCTGGCGACGCTGG
ATGAACTGCCGGAGCTCGATCTGTGCATCGACGGTGCCGACGAGATCGGCCCGGAGCTCGCTCTCATCAAGGGTGGTGGC
GGCGCTCTGCTGCGCGAGAAGATCGTCGCCAGCGCCGCCCGCGAGATGATCGTCATTGCCGACGAGACCAAGACTGTCGC
GACCCTCGGCCGCTTTCCCCTGCCCATCGAGGTCGTGACCTTCGGCGTCGAGGCCATCAAGCTGCGGCTGAAGGGCGCCA
TCGCGACGGCCGGATGCGATGGCGAGCTGAAGCTGCGCCACAAGGCGGATGGCAAGCCCTTCATCACCGATCAGGGCAAT
GTGATCGTCGACGCGCATCTCGGCCGCATCCCCGATCCGCGTGCACTCGCCCGTGCGCTGGAAGAGGTGGCCGGCGTCGT
GGAGCATGGCCTGTTCCTCGGCCTCGCCCGCCGCGCGGTGCTCGCCGGCGCCAATGGCATTTCGGTCATCACGCCCTGA

Upstream 100 bases:

>100_bases
ACGAGTGTCCCGTCGAGGTCGAAGGCGATCACCGGGCGAACCTGAGACATGACGCAATCCCTGCTGAAGTCATCGGAGCA
AACGCGGCGCACGGGGCGCC

Downstream 100 bases:

>100_bases
GGACGAGCGGCCGGAAGCGGCAAGCTTCTGGATGCATCCCACTCTGGATCAGTTATAGAGAACGCCCCTTCTGGAGAATG
TCATGGCTGTGTTTCCCTCG

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPPCRRFGRTFKGGVCGTARVAGAPLCLFKPGGRGTRRCASRLRFAPFAARQPANRWSTDMADAEELKRAAAAKALEYVT
DGMRLGLGTGSTAKHFVALLAERVAAGLKVTGVPTSEQTKAQALSLGVPLATLDELPELDLCIDGADEIGPELALIKGGG
GALLREKIVASAAREMIVIADETKTVATLGRFPLPIEVVTFGVEAIKLRLKGAIATAGCDGELKLRHKADGKPFITDQGN
VIVDAHLGRIPDPRALARALEEVAGVVEHGLFLGLARRAVLAGANGISVITP

Sequences:

>Translated_292_residues
MPPCRRFGRTFKGGVCGTARVAGAPLCLFKPGGRGTRRCASRLRFAPFAARQPANRWSTDMADAEELKRAAAAKALEYVT
DGMRLGLGTGSTAKHFVALLAERVAAGLKVTGVPTSEQTKAQALSLGVPLATLDELPELDLCIDGADEIGPELALIKGGG
GALLREKIVASAAREMIVIADETKTVATLGRFPLPIEVVTFGVEAIKLRLKGAIATAGCDGELKLRHKADGKPFITDQGN
VIVDAHLGRIPDPRALARALEEVAGVVEHGLFLGLARRAVLAGANGISVITP
>Mature_291_residues
PPCRRFGRTFKGGVCGTARVAGAPLCLFKPGGRGTRRCASRLRFAPFAARQPANRWSTDMADAEELKRAAAAKALEYVTD
GMRLGLGTGSTAKHFVALLAERVAAGLKVTGVPTSEQTKAQALSLGVPLATLDELPELDLCIDGADEIGPELALIKGGGG
ALLREKIVASAAREMIVIADETKTVATLGRFPLPIEVVTFGVEAIKLRLKGAIATAGCDGELKLRHKADGKPFITDQGNV
IVDAHLGRIPDPRALARALEEVAGVVEHGLFLGLARRAVLAGANGISVITP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=237, Percent_Identity=38.3966244725738, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1789280, Length=213, Percent_Identity=40.3755868544601, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=228, Percent_Identity=41.2280701754386, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324669, Length=244, Percent_Identity=34.4262295081967, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281364072, Length=220, Percent_Identity=38.6363636363636, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 30513; Mature: 30382

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPCRRFGRTFKGGVCGTARVAGAPLCLFKPGGRGTRRCASRLRFAPFAARQPANRWSTD
CCCHHHHCCCCCCCCCCCHHHCCCCEEEECCCCCHHHHHHHHHCCCCCHHCCCCCCCCCC
MADAEELKRAAAAKALEYVTDGMRLGLGTGSTAKHFVALLAERVAAGLKVTGVPTSEQTK
CCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHH
AQALSLGVPLATLDELPELDLCIDGADEIGPELALIKGGGGALLREKIVASAAREMIVIA
HHHHHCCCCHHHHHCCCCCEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHHHCEEEEE
DETKTVATLGRFPLPIEVVTFGVEAIKLRLKGAIATAGCDGELKLRHKADGKPFITDQGN
CCCHHHHHHCCCCCCHHHHHHHHHHHHEEECCEEEECCCCCCEEEEECCCCCCEEECCCC
VIVDAHLGRIPDPRALARALEEVAGVVEHGLFLGLARRAVLAGANGISVITP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
PPCRRFGRTFKGGVCGTARVAGAPLCLFKPGGRGTRRCASRLRFAPFAARQPANRWSTD
CCHHHHCCCCCCCCCCCHHHCCCCEEEECCCCCHHHHHHHHHCCCCCHHCCCCCCCCCC
MADAEELKRAAAAKALEYVTDGMRLGLGTGSTAKHFVALLAERVAAGLKVTGVPTSEQTK
CCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHH
AQALSLGVPLATLDELPELDLCIDGADEIGPELALIKGGGGALLREKIVASAAREMIVIA
HHHHHCCCCHHHHHCCCCCEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHHHCEEEEE
DETKTVATLGRFPLPIEVVTFGVEAIKLRLKGAIATAGCDGELKLRHKADGKPFITDQGN
CCCHHHHHHCCCCCCHHHHHHHHHHHHEEECCEEEECCCCCCEEEEECCCCCCEEECCCC
VIVDAHLGRIPDPRALARALEEVAGVVEHGLFLGLARRAVLAGANGISVITP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]