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The map label for this gene is ttuB [H]

Identifier: 158423892

GI number: 158423892

Start: 2592826

End: 2594166

Strand: Reverse

Name: ttuB [H]

Synonym: AZC_2268

Alternate gene names: 158423892

Gene position: 2594166-2592826 (Counterclockwise)

Preceding gene: 158423893

Following gene: 158423891

Centisome position: 48.31

GC content: 66.22

Gene sequence:

>1341_bases
ATGCTGGGAGAAACGGCCATGTCATCCATCGCCATGGATGCATCTGCTGCCGACGGCGAAGCCATGCGCAAGCGCATCGC
TTCCAAGCTGCGCTGGCGGATCGTCTTTTACTGCTTCGTCCTGTTCATCGTGAATTACCTCGACCGTGTGAACGTGGGCT
TTGCCGCCACGCACATGAACAAGGATCTCGGGCTTTCGGCGACCGCCTACGGGTTCGGCGCCGGCGTCTTCTTCCTCGGC
TACATCGCCTTCGAGATCCCCAGCAACATGATGATGCACAAGGTGGGCGCCCGCATCTGGATCGCCCGCATCATGGTGAC
GTGGGGCCTCATCTCCTGTGCCATGGCTTTCATCCAGGGCGAGACCAGCTTTTATATCCTGCGCTTCCTGCTGGGCGCGG
CCGAAGCCGGCTTCGTGCCCGGCATCCTGCTCTATCTGACCTACTGGTTCCCGGCCCGCGACCGCGCCAAGGCGACCGCC
GGCTTCATGACGGCCACCGTCCTGTCCACCGTGATCGGCGCCCCCATCTCCGGCTGGATCCTCGCCACCGTGCCCAACTG
GCACGGGCTCGCCAACTGGCAGTGGCTCTTCATCCTCGAGGGCCTGCCGGCGGTGATCCTCGGTGTCTTCACCTTCTTCT
ATCTCGTGGACCGTCCGCAGGATGGCCGCTGGCTGGACGAAGCGGAGCGCGAGTGGCTCATCGCCGAACTGGAGCGCGAG
AACCGGGAGGTCGCCAACACCGGCGCGCACGAATATGGCGCGATCTTCCGCGATCCGCGTGTGTGGTTGCTCACCCTCAT
CTACATGTTCAACGCCATGGCGGTGTACGGGGTAGTGCTCTGGCTGCCGCAGATCGTACGCTCCATCGGCGGCCTCTCCG
ACATTCAGACCGGCTTTGTCACCGCCGTGCCCTTCGTCTTCGCCGCGATCGGCCTCGTGCTCGTGGCCCGCAGTTCCGAC
CGCACCGGCGAGCGCAAGTGGCACACGGCTCTCGCGGCGCTCTTCGGCGGCCTGTTCCTCGCGGCGAGTGCCGTAGCGCC
GACGCCGCTGGTCGGGCTGATGCTGATCAGCGCGGCTGCCTTCGGTGTGTGGGCGGTGCTGGGCGTATTCTGGTCGCTGC
CGACGCAGTTCCTCACCGGCGCTGCCGCTGCGGCGGGGCTGGCCGCCATCAACGGCTTTGCCCAGATCGGCGGCTTCGCC
GGTCCCTATCTCGTGGGCTGGATCAAGGACACCACCCAGAGCTTCACGCCGGCCCTGCTGACGCTGGCCGCCGGCCCGGT
GATCGCCGCCATCCTCTGCCTCGCCATTAAGGTGAAGGCCCCGGCGGGCGGGCGCCGGTAG

Upstream 100 bases:

>100_bases
TCGGGCGGCCGCGCCACCTACTGAGCACCGACCATTCGGGTGCCCTCTGTCGCCGGCGGACAACGTTTCCGCCGGCGTCC
AATAAAAAACGCCAATATTC

Downstream 100 bases:

>100_bases
GCCAAAGGAGGAAGCGCATGCGGCAGCGCCGGCGCTTCCGTTGCCGGCTCGCCGGGTCTAAGAGCTTCGACGCGCGCGCC
ATCCGGTGCGCGCGTTTTGC

Product: MFS permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MLGETAMSSIAMDASAADGEAMRKRIASKLRWRIVFYCFVLFIVNYLDRVNVGFAATHMNKDLGLSATAYGFGAGVFFLG
YIAFEIPSNMMMHKVGARIWIARIMVTWGLISCAMAFIQGETSFYILRFLLGAAEAGFVPGILLYLTYWFPARDRAKATA
GFMTATVLSTVIGAPISGWILATVPNWHGLANWQWLFILEGLPAVILGVFTFFYLVDRPQDGRWLDEAEREWLIAELERE
NREVANTGAHEYGAIFRDPRVWLLTLIYMFNAMAVYGVVLWLPQIVRSIGGLSDIQTGFVTAVPFVFAAIGLVLVARSSD
RTGERKWHTALAALFGGLFLAASAVAPTPLVGLMLISAAAFGVWAVLGVFWSLPTQFLTGAAAAAGLAAINGFAQIGGFA
GPYLVGWIKDTTQSFTPALLTLAAGPVIAAILCLAIKVKAPAGGRR

Sequences:

>Translated_446_residues
MLGETAMSSIAMDASAADGEAMRKRIASKLRWRIVFYCFVLFIVNYLDRVNVGFAATHMNKDLGLSATAYGFGAGVFFLG
YIAFEIPSNMMMHKVGARIWIARIMVTWGLISCAMAFIQGETSFYILRFLLGAAEAGFVPGILLYLTYWFPARDRAKATA
GFMTATVLSTVIGAPISGWILATVPNWHGLANWQWLFILEGLPAVILGVFTFFYLVDRPQDGRWLDEAEREWLIAELERE
NREVANTGAHEYGAIFRDPRVWLLTLIYMFNAMAVYGVVLWLPQIVRSIGGLSDIQTGFVTAVPFVFAAIGLVLVARSSD
RTGERKWHTALAALFGGLFLAASAVAPTPLVGLMLISAAAFGVWAVLGVFWSLPTQFLTGAAAAAGLAAINGFAQIGGFA
GPYLVGWIKDTTQSFTPALLTLAAGPVIAAILCLAIKVKAPAGGRR
>Mature_446_residues
MLGETAMSSIAMDASAADGEAMRKRIASKLRWRIVFYCFVLFIVNYLDRVNVGFAATHMNKDLGLSATAYGFGAGVFFLG
YIAFEIPSNMMMHKVGARIWIARIMVTWGLISCAMAFIQGETSFYILRFLLGAAEAGFVPGILLYLTYWFPARDRAKATA
GFMTATVLSTVIGAPISGWILATVPNWHGLANWQWLFILEGLPAVILGVFTFFYLVDRPQDGRWLDEAEREWLIAELERE
NREVANTGAHEYGAIFRDPRVWLLTLIYMFNAMAVYGVVLWLPQIVRSIGGLSDIQTGFVTAVPFVFAAIGLVLVARSSD
RTGERKWHTALAALFGGLFLAASAVAPTPLVGLMLISAAAFGVWAVLGVFWSLPTQFLTGAAAAAGLAAINGFAQIGGFA
GPYLVGWIKDTTQSFTPALLTLAAGPVIAAILCLAIKVKAPAGGRR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=476, Percent_Identity=21.218487394958, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=38.3333333333333, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1789152, Length=457, Percent_Identity=27.5711159737418, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367379, Length=414, Percent_Identity=24.1545893719807, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789515, Length=438, Percent_Identity=23.5159817351598, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87082320, Length=422, Percent_Identity=21.8009478672986, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367193, Length=449, Percent_Identity=23.3853006681514, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25141318, Length=353, Percent_Identity=22.6628895184136, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=390, Percent_Identity=22.5641025641026, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=299, Percent_Identity=23.4113712374582, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=304, Percent_Identity=21.7105263157895, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17569727, Length=253, Percent_Identity=23.7154150197628, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983953, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562692, Length=225, Percent_Identity=24.8888888888889, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322025, Length=198, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=327, Percent_Identity=23.5474006116208, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322612, Length=280, Percent_Identity=23.2142857142857, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=218, Percent_Identity=26.605504587156, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=292, Percent_Identity=22.9452054794521, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=144, Percent_Identity=24.3055555555556, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584153, Length=368, Percent_Identity=22.554347826087, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583789, Length=377, Percent_Identity=23.8726790450928, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48319; Mature: 48319

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGETAMSSIAMDASAADGEAMRKRIASKLRWRIVFYCFVLFIVNYLDRVNVGFAATHMN
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCC
KDLGLSATAYGFGAGVFFLGYIAFEIPSNMMMHKVGARIWIARIMVTWGLISCAMAFIQG
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETSFYILRFLLGAAEAGFVPGILLYLTYWFPARDRAKATAGFMTATVLSTVIGAPISGWI
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
LATVPNWHGLANWQWLFILEGLPAVILGVFTFFYLVDRPQDGRWLDEAEREWLIAELERE
EEECCCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
NREVANTGAHEYGAIFRDPRVWLLTLIYMFNAMAVYGVVLWLPQIVRSIGGLSDIQTGFV
HHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TAVPFVFAAIGLVLVARSSDRTGERKWHTALAALFGGLFLAASAVAPTPLVGLMLISAAA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FGVWAVLGVFWSLPTQFLTGAAAAAGLAAINGFAQIGGFAGPYLVGWIKDTTQSFTPALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TLAAGPVIAAILCLAIKVKAPAGGRR
HHHHHHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MLGETAMSSIAMDASAADGEAMRKRIASKLRWRIVFYCFVLFIVNYLDRVNVGFAATHMN
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCC
KDLGLSATAYGFGAGVFFLGYIAFEIPSNMMMHKVGARIWIARIMVTWGLISCAMAFIQG
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETSFYILRFLLGAAEAGFVPGILLYLTYWFPARDRAKATAGFMTATVLSTVIGAPISGWI
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
LATVPNWHGLANWQWLFILEGLPAVILGVFTFFYLVDRPQDGRWLDEAEREWLIAELERE
EEECCCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
NREVANTGAHEYGAIFRDPRVWLLTLIYMFNAMAVYGVVLWLPQIVRSIGGLSDIQTGFV
HHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TAVPFVFAAIGLVLVARSSDRTGERKWHTALAALFGGLFLAASAVAPTPLVGLMLISAAA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
FGVWAVLGVFWSLPTQFLTGAAAAAGLAAINGFAQIGGFAGPYLVGWIKDTTQSFTPALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TLAAGPVIAAILCLAIKVKAPAGGRR
HHHHHHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]