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The map label for this gene is lipB [H]

Identifier: 158423888

GI number: 158423888

Start: 2588012

End: 2588806

Strand: Reverse

Name: lipB [H]

Synonym: AZC_2264

Alternate gene names: 158423888

Gene position: 2588806-2588012 (Counterclockwise)

Preceding gene: 158423891

Following gene: 158423883

Centisome position: 48.21

GC content: 63.65

Gene sequence:

>795_bases
ATGACGCTCAAATTCACCATTCTGGGCTGTGGCTCTTCCGGCGGCGTTCCCCGCGTGGGGCAGGGCTGGGGCGCCTGCGA
TCCGAACGAACCGCGCAACCGCCGCCGCCGCTGCTCCCTGCTTGTCCAGCGCACCGGCCCCGACGGCGTGACCACCGTGC
TCGTCGACGCCTCTCCAGACCTGCGCGAACAGTTGCTGGACGTGGGCGTCACCCATGTGGATGCCCTTCTCATCACCCAT
GAGCATGCCGACCACACCCACGGCATCGACGACGTGCGCCCGCTGGTCATCCACAACCGCCGCCGCATGGACGTGTATAT
GGACGAGGAGACCGCCCGCGCCATGCACGCGCGCTTCGGCTACTGCTTCGTGACGCCGCCGGGCAGCAACTATCCGCCCA
TCCTCACCGAGCACCGCTTTCATGAGGGCCGCGAGATCACCGTGCCGGGGCAGGGCGGTCCCATAACCGCCTTGCCGTTC
CGCCAGCACCATGGCGACATCGATTCGTTCGGCTTCAGATTTGGTGGCGTCGCCTATTCAAGCGACGTCAGCGCTTTTCC
GCAGAACAGTCTGAAAGCCTTGGAGAATCTTGACGTCTGGATTCTTGATGCACTGCGTGAAACGCCCCACCCAAGCCATT
TCAGCCTTTCGGAGGCGCTGGAGCATGAGGAGCGCATGCGCCCTGCCCGCACCATCCTCACGAACCTCCATACCGATCTA
GACTATGGGAAGCTGAAGGCACGCCTGCCCGAACGCATCATTCCCGCGTTCGACGGAATGATTTTCGAGGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGCAGCTTTCGGCGGAGGGAGGGGGAGGCTTGGAGAATCCCCTGACACGGCCTAAGGGTCGAAAGGCCGCGCGAAG
GCGGTGCAGGCGGGCTTCCC

Downstream 100 bases:

>100_bases
TCCACCGCTTCTCCACATGAGAAGATGGAACCAACCATCTGCTGGCAGAGCCGATTTTCGGCTTATCCTCATGCTCCACA
TCACGTGAAGAGATTGAGCG

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTLKFTILGCGSSGGVPRVGQGWGACDPNEPRNRRRRCSLLVQRTGPDGVTTVLVDASPDLREQLLDVGVTHVDALLITH
EHADHTHGIDDVRPLVIHNRRRMDVYMDEETARAMHARFGYCFVTPPGSNYPPILTEHRFHEGREITVPGQGGPITALPF
RQHHGDIDSFGFRFGGVAYSSDVSAFPQNSLKALENLDVWILDALRETPHPSHFSLSEALEHEERMRPARTILTNLHTDL
DYGKLKARLPERIIPAFDGMIFEA

Sequences:

>Translated_264_residues
MTLKFTILGCGSSGGVPRVGQGWGACDPNEPRNRRRRCSLLVQRTGPDGVTTVLVDASPDLREQLLDVGVTHVDALLITH
EHADHTHGIDDVRPLVIHNRRRMDVYMDEETARAMHARFGYCFVTPPGSNYPPILTEHRFHEGREITVPGQGGPITALPF
RQHHGDIDSFGFRFGGVAYSSDVSAFPQNSLKALENLDVWILDALRETPHPSHFSLSEALEHEERMRPARTILTNLHTDL
DYGKLKARLPERIIPAFDGMIFEA
>Mature_263_residues
TLKFTILGCGSSGGVPRVGQGWGACDPNEPRNRRRRCSLLVQRTGPDGVTTVLVDASPDLREQLLDVGVTHVDALLITHE
HADHTHGIDDVRPLVIHNRRRMDVYMDEETARAMHARFGYCFVTPPGSNYPPILTEHRFHEGREITVPGQGGPITALPFR
QHHGDIDSFGFRFGGVAYSSDVSAFPQNSLKALENLDVWILDALRETPHPSHFSLSEALEHEERMRPARTILTNLHTDLD
YGKLKARLPERIIPAFDGMIFEA

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29513; Mature: 29382

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKFTILGCGSSGGVPRVGQGWGACDPNEPRNRRRRCSLLVQRTGPDGVTTVLVDASPD
CEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEEEECCHH
LREQLLDVGVTHVDALLITHEHADHTHGIDDVRPLVIHNRRRMDVYMDEETARAMHARFG
HHHHHHHHCHHHHHEEEEEECCCCCCCCCCCCCHHEEECCCCEEEEECHHHHHHHHHHCC
YCFVTPPGSNYPPILTEHRFHEGREITVPGQGGPITALPFRQHHGDIDSFGFRFGGVAYS
EEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCHHHCCCCHHCCCCCCCEEEC
SDVSAFPQNSLKALENLDVWILDALRETPHPSHFSLSEALEHEERMRPARTILTNLHTDL
CCCCCCCHHHHHHHHCCCHHEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DYGKLKARLPERIIPAFDGMIFEA
CHHHHHHHCHHHHHHHHCCEEECC
>Mature Secondary Structure 
TLKFTILGCGSSGGVPRVGQGWGACDPNEPRNRRRRCSLLVQRTGPDGVTTVLVDASPD
EEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEEEECCHH
LREQLLDVGVTHVDALLITHEHADHTHGIDDVRPLVIHNRRRMDVYMDEETARAMHARFG
HHHHHHHHCHHHHHEEEEEECCCCCCCCCCCCCHHEEECCCCEEEEECHHHHHHHHHHCC
YCFVTPPGSNYPPILTEHRFHEGREITVPGQGGPITALPFRQHHGDIDSFGFRFGGVAYS
EEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCHHHCCCCHHCCCCCCCEEEC
SDVSAFPQNSLKALENLDVWILDALRETPHPSHFSLSEALEHEERMRPARTILTNLHTDL
CCCCCCCHHHHHHHHCCCHHEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DYGKLKARLPERIIPAFDGMIFEA
CHHHHHHHCHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]