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The map label for this gene is trpD

Identifier: 158423830

GI number: 158423830

Start: 2520226

End: 2521260

Strand: Reverse

Name: trpD

Synonym: AZC_2206

Alternate gene names: 158423830

Gene position: 2521260-2520226 (Counterclockwise)

Preceding gene: 158423831

Following gene: 158423829

Centisome position: 46.95

GC content: 69.76

Gene sequence:

>1035_bases
ATGGAACGCTTCCGCCCCCTCCTGAACAAGGTCGCCATGGGCACGGCGCTCAACCGCGACGAGGCGGCCTACGCCTTCGA
CAAGATGATGTCCGGCGAGACGACGCCCTCGCAGATGGGCGCGCTGCTCATGGGCCTGCGGGTGCGCGGGGAGACGGTGG
ACGAGATCGTCGGCGCCGTCTCCGTCATGCGCGCCAAGATGCTGACCGTGGACGCCCCCGTCGGATCGGTGGACGTGGTG
GGCACGGGCGGCGACGCTTCGGGCTCCTACAACATCTCCACCTGCGCCTCCTTCATCGTCGCGGGCGCCGGCGTGCCGGT
GGCCAAGCACGGCAACCGCGCGCTTTCCTCCAAGTCCGGCGCGGCGGATGTGCTGGCAGCGTTGGGCGTGCGCATTGACC
TCGCGCCCGCCGCCATCTCGCGCTGCATTGCGGAGACCGGCATCGGCTTCATGTTCGCGCCGACGCATCATCCGGCCATG
AAGAACGTCGGCCCGACGCGCGTGGAGCTGGGCACCCGCACCATATTCAACCTGCTCGGCCCGCTCTCCAATCCGGCCGG
CGTCAAGCGCCAGATGGTGGGCGTGTTCGCCAAAGCCTGGCTTTCGCCGCTGGCCGAGGTGCTCAAAGCCCTCGGTTCCG
AGCGCGCCTGGGTGGTGCACGGCTCCGATGGCCTCGACGAGATCACCATTTCGGGCACGACGGACGTGGCAAGCCTCGAA
GACGGGCGCGTGCACACGTTCGAGATCAGCCCGGAGGACGTGGGCCTGACCCGCGCCGCACCGGAAGCGCTGCGCGGCGG
GGATGCCGAGCACAATGCAGCGGCATTGCGCGCCGTGCTTGAGGGCGCCCCCGGCGCCTATCGCGACGTCGCCGTCATGA
ATGCCGGCGCCGCCCTCCTCATTTCCGGCCGCGCCGCCTCCTTGCGCGACGGAGTGGACATGGCCAAGGCCAGCATCGAT
AGCGGCGCCGCCAAGGCGAAGCTTGATCAACTTGCCCGCGCCACGCAGGCGCTCGCCCCGCAGGTGGACGCATGA

Upstream 100 bases:

>100_bases
CATCCCGAGAGCATCGCCTCCGAGAATGGCCATGCGCTGATGCGCAACTTCCTCGACATCGCCACCGCGTTCAACGCCGC
GCGCGCCAAGGACTGACCCG

Downstream 100 bases:

>100_bases
GCGACATTCTTTCCCGCATCGAGACCTACAAGCGCGCCGAGATCGAAGCCGCCCGCGCCGCGCGTCCGCAGGCCGAGACC
GAGGCGGCCGCCCGCGCCGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MERFRPLLNKVAMGTALNRDEAAYAFDKMMSGETTPSQMGALLMGLRVRGETVDEIVGAVSVMRAKMLTVDAPVGSVDVV
GTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSGAADVLAALGVRIDLAPAAISRCIAETGIGFMFAPTHHPAM
KNVGPTRVELGTRTIFNLLGPLSNPAGVKRQMVGVFAKAWLSPLAEVLKALGSERAWVVHGSDGLDEITISGTTDVASLE
DGRVHTFEISPEDVGLTRAAPEALRGGDAEHNAAALRAVLEGAPGAYRDVAVMNAGAALLISGRAASLRDGVDMAKASID
SGAAKAKLDQLARATQALAPQVDA

Sequences:

>Translated_344_residues
MERFRPLLNKVAMGTALNRDEAAYAFDKMMSGETTPSQMGALLMGLRVRGETVDEIVGAVSVMRAKMLTVDAPVGSVDVV
GTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSGAADVLAALGVRIDLAPAAISRCIAETGIGFMFAPTHHPAM
KNVGPTRVELGTRTIFNLLGPLSNPAGVKRQMVGVFAKAWLSPLAEVLKALGSERAWVVHGSDGLDEITISGTTDVASLE
DGRVHTFEISPEDVGLTRAAPEALRGGDAEHNAAALRAVLEGAPGAYRDVAVMNAGAALLISGRAASLRDGVDMAKASID
SGAAKAKLDQLARATQALAPQVDA
>Mature_344_residues
MERFRPLLNKVAMGTALNRDEAAYAFDKMMSGETTPSQMGALLMGLRVRGETVDEIVGAVSVMRAKMLTVDAPVGSVDVV
GTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSGAADVLAALGVRIDLAPAAISRCIAETGIGFMFAPTHHPAM
KNVGPTRVELGTRTIFNLLGPLSNPAGVKRQMVGVFAKAWLSPLAEVLKALGSERAWVVHGSDGLDEITISGTTDVASLE
DGRVHTFEISPEDVGLTRAAPEALRGGDAEHNAAALRAVLEGAPGAYRDVAVMNAGAALLISGRAASLRDGVDMAKASID
SGAAKAKLDQLARATQALAPQVDA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=280, Percent_Identity=40.3571428571429, Blast_Score=211, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6320561, Length=286, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_AZOC5 (A8I839)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001525122.1
- ProteinModelPortal:   A8I839
- SMR:   A8I839
- GeneID:   5689546
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_2206
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- BioCyc:   ACAU438753:AZC_2206-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35310; Mature: 35310

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFRPLLNKVAMGTALNRDEAAYAFDKMMSGETTPSQMGALLMGLRVRGETVDEIVGAV
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SVMRAKMLTVDAPVGSVDVVGTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSG
HHHHHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
AADVLAALGVRIDLAPAAISRCIAETGIGFMFAPTHHPAMKNVGPTRVELGTRTIFNLLG
HHHHHHHHCCEEEECHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEHHHHHHHHHHHC
PLSNPAGVKRQMVGVFAKAWLSPLAEVLKALGSERAWVVHGSDGLDEITISGTTDVASLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCC
DGRVHTFEISPEDVGLTRAAPEALRGGDAEHNAAALRAVLEGAPGAYRDVAVMNAGAALL
CCCEEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCEEEE
ISGRAASLRDGVDMAKASIDSGAAKAKLDQLARATQALAPQVDA
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MERFRPLLNKVAMGTALNRDEAAYAFDKMMSGETTPSQMGALLMGLRVRGETVDEIVGAV
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SVMRAKMLTVDAPVGSVDVVGTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSG
HHHHHHHHEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
AADVLAALGVRIDLAPAAISRCIAETGIGFMFAPTHHPAMKNVGPTRVELGTRTIFNLLG
HHHHHHHHCCEEEECHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEHHHHHHHHHHHC
PLSNPAGVKRQMVGVFAKAWLSPLAEVLKALGSERAWVVHGSDGLDEITISGTTDVASLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCC
DGRVHTFEISPEDVGLTRAAPEALRGGDAEHNAAALRAVLEGAPGAYRDVAVMNAGAALL
CCCEEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCEEEE
ISGRAASLRDGVDMAKASIDSGAAKAKLDQLARATQALAPQVDA
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA