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The map label for this gene is yajO [H]

Identifier: 158423818

GI number: 158423818

Start: 2507959

End: 2508939

Strand: Reverse

Name: yajO [H]

Synonym: AZC_2194

Alternate gene names: 158423818

Gene position: 2508939-2507959 (Counterclockwise)

Preceding gene: 158423820

Following gene: 158423817

Centisome position: 46.72

GC content: 66.26

Gene sequence:

>981_bases
ATGGATTATGTGAAGCTCGGCCGTACCGGCCTTGAAGTCTCGCGCCTTTGCCTCGGCTGCATGAGCTATGGGGCACCGAA
CCGGGGCACGCACCCCTGGTCGCTTCCGGAGGAGGAAAGCCGTCCCTTCATCCGCAAGGCACTGGAAGCGGGGATCAATT
TCTTCGACACCGCCAACGTCTATTCCGACGGCACCAGCGAGGAGTTCCTGGGACGGGCGCTGCGCGATTTTGCCAAGCGC
GAGGAGGTGGTGATCGCCACCAAGGTGTTCAACCGCATGCGCCCCGGCCCCAATGGCGCCGGTCTCGGCCGCAAGGCGAT
CCTGGCGGAGATCGACAATAGCCTGCGCCGCCTCGGCACCGATTACGTGGACCTCTACCAGATCCACCGCTGGGACTATG
ACACGCCCATCGAGGAGACGCTTGAGGCGCTGGACACCGTCGTCCGTTCCGGCAAGGCGCGCTACATCGGCGCCTCCTCC
ATGCATGCGTGGCAGTTCGCCAAGGCCCTGTTCCTGCAGGAAAAGCACGGCTGGACCCGCTTCGTGAGCATGCAGAACCT
CGTGAACCTGCTCTATCGCGAGGAGGAACGGGACATGCTGCCGCTCTGTGCCGATCAGGGCGTCGGCGTCATCCCCTGGA
GCCCGCTCGCCCGTGGCCGCCTCACCCGCCCGTGGGACGAAACCAGCGCCCGTTCCGAAACCGACGAATTCGGCAAGACG
CTCTGGACCCGCACCGCCGACGCCGACCGCAAGGTGGTGGACCGGGTACGCGAGGTGGCGACGGCGCGGGGCGTGCCTGC
GGCGCAGGTGGCGCTGGCCTGGGTGCTCCAGAAGTCGGTCATCACCGCGCCCATCATCGGCGCCACCAAGCCGGCCCATC
TCGACGATGCCATCGGTGCCTTGTCGCTGAAGCTGGAGCCGGCCGAGATCGCGGCGCTGGAAGAGCCCTACGTTCCTCAC
GGCGTCATCGGGTTCAAGTGA

Upstream 100 bases:

>100_bases
ATTCGCGCCCGTAAAGAAAAATGCTCGGCTTTCCCCCAGCCGCGCGTATGGTCCCGTCCTGCCTTGCGGCGTCCGCCGCG
CATGAAAGAGGCCATCCCAC

Downstream 100 bases:

>100_bases
GGCACGAGCCGCGGTCGCCCGGTGCTTTTCCGGCGACCGTGACCCCGCCACCACGGCGTCGGCGGAACCCTGCCGGCGCC
TGACGCGCGGAGCCTGGGGA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MDYVKLGRTGLEVSRLCLGCMSYGAPNRGTHPWSLPEEESRPFIRKALEAGINFFDTANVYSDGTSEEFLGRALRDFAKR
EEVVIATKVFNRMRPGPNGAGLGRKAILAEIDNSLRRLGTDYVDLYQIHRWDYDTPIEETLEALDTVVRSGKARYIGASS
MHAWQFAKALFLQEKHGWTRFVSMQNLVNLLYREEERDMLPLCADQGVGVIPWSPLARGRLTRPWDETSARSETDEFGKT
LWTRTADADRKVVDRVREVATARGVPAAQVALAWVLQKSVITAPIIGATKPAHLDDAIGALSLKLEPAEIAALEEPYVPH
GVIGFK

Sequences:

>Translated_326_residues
MDYVKLGRTGLEVSRLCLGCMSYGAPNRGTHPWSLPEEESRPFIRKALEAGINFFDTANVYSDGTSEEFLGRALRDFAKR
EEVVIATKVFNRMRPGPNGAGLGRKAILAEIDNSLRRLGTDYVDLYQIHRWDYDTPIEETLEALDTVVRSGKARYIGASS
MHAWQFAKALFLQEKHGWTRFVSMQNLVNLLYREEERDMLPLCADQGVGVIPWSPLARGRLTRPWDETSARSETDEFGKT
LWTRTADADRKVVDRVREVATARGVPAAQVALAWVLQKSVITAPIIGATKPAHLDDAIGALSLKLEPAEIAALEEPYVPH
GVIGFK
>Mature_326_residues
MDYVKLGRTGLEVSRLCLGCMSYGAPNRGTHPWSLPEEESRPFIRKALEAGINFFDTANVYSDGTSEEFLGRALRDFAKR
EEVVIATKVFNRMRPGPNGAGLGRKAILAEIDNSLRRLGTDYVDLYQIHRWDYDTPIEETLEALDTVVRSGKARYIGASS
MHAWQFAKALFLQEKHGWTRFVSMQNLVNLLYREEERDMLPLCADQGVGVIPWSPLARGRLTRPWDETSARSETDEFGKT
LWTRTADADRKVVDRVREVATARGVPAAQVALAWVLQKSVITAPIIGATKPAHLDDAIGALSLKLEPAEIAALEEPYVPH
GVIGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=29.4871794871795, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=29.4871794871795, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=29.1666666666667, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=29.8076923076923, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4504825, Length=310, Percent_Identity=29.6774193548387, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436971, Length=338, Percent_Identity=30.1775147928994, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI223718702, Length=301, Percent_Identity=26.9102990033223, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI41327764, Length=288, Percent_Identity=27.4305555555556, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=292, Percent_Identity=27.7397260273973, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=35.2517985611511, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=63.4969325153374, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=36.4741641337386, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=30.5714285714286, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=30.1492537313433, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=33.6633663366337, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082198, Length=295, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=319, Percent_Identity=24.7648902821317, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17550248, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=40, Blast_Score=249, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=31.8318318318318, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=31.6326530612245, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6319951, Length=341, Percent_Identity=30.2052785923754, Blast_Score=136, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=31.640625, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=31.4102564102564, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646155, Length=284, Percent_Identity=31.6901408450704, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24640980, Length=330, Percent_Identity=26.0606060606061, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=25.7668711656442, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646159, Length=169, Percent_Identity=37.8698224852071, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36385; Mature: 36385

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYVKLGRTGLEVSRLCLGCMSYGAPNRGTHPWSLPEEESRPFIRKALEAGINFFDTANV
CCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCCC
YSDGTSEEFLGRALRDFAKREEVVIATKVFNRMRPGPNGAGLGRKAILAEIDNSLRRLGT
CCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DYVDLYQIHRWDYDTPIEETLEALDTVVRSGKARYIGASSMHAWQFAKALFLQEKHGWTR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHH
FVSMQNLVNLLYREEERDMLPLCADQGVGVIPWSPLARGRLTRPWDETSARSETDEFGKT
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHH
LWTRTADADRKVVDRVREVATARGVPAAQVALAWVLQKSVITAPIIGATKPAHLDDAIGA
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LSLKLEPAEIAALEEPYVPHGVIGFK
EEEEECHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDYVKLGRTGLEVSRLCLGCMSYGAPNRGTHPWSLPEEESRPFIRKALEAGINFFDTANV
CCCHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCCC
YSDGTSEEFLGRALRDFAKREEVVIATKVFNRMRPGPNGAGLGRKAILAEIDNSLRRLGT
CCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DYVDLYQIHRWDYDTPIEETLEALDTVVRSGKARYIGASSMHAWQFAKALFLQEKHGWTR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHH
FVSMQNLVNLLYREEERDMLPLCADQGVGVIPWSPLARGRLTRPWDETSARSETDEFGKT
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHH
LWTRTADADRKVVDRVREVATARGVPAAQVALAWVLQKSVITAPIIGATKPAHLDDAIGA
HHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LSLKLEPAEIAALEEPYVPHGVIGFK
EEEEECHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]