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The map label for this gene is blh [H]

Identifier: 158423706

GI number: 158423706

Start: 2397137

End: 2398030

Strand: Reverse

Name: blh [H]

Synonym: AZC_2082

Alternate gene names: 158423706

Gene position: 2398030-2397137 (Counterclockwise)

Preceding gene: 158423707

Following gene: 158423705

Centisome position: 44.66

GC content: 63.98

Gene sequence:

>894_bases
ATGCTCCCGATCCCGCACGCCGTTGACCTGTCCGTCAAACCGGAGGTGACCGCCTTCTTCGACGCGCCCACCAACACCGT
GAGCTATGTGGTGAAGGACCCGCAGTCGAACGCCTGTGCCGTCATCGACAGCGTCATGGACATCGATTACGCGGCCGGCC
GCATCGCCTTCCAGTCCGCAGACGCGATCATCGCGTTCATCCAGGACCACGGACTCCGGCTGGAATGGCTCATCGAGACC
CACGCGCATGCCGATCATCTTTCCGCCGCGCCTTATATCCAGCGGACCCTCGGCGGACAGATGGGTATCGGTGAAAACAT
CACCATCGTTCAGGAGACCTTCGGCAAGATCTTCAACGAAGGCACGGAATTCCAGCGCGACGGCAGCCAGTTCGACCGGC
TGTTCAAGGACGGCGATACCTACCGGATCGGTAGCATGACGGCCTTCGCCATGCACACGCCCGGCCATACGCCCGCCTGC
ATGACCCACGTGATCGGCAATGCCGCCTTTGTCGGCGACACGCTGTTCATGCCTGACGGCGGCACGGCGCGGGCCGACTT
TCCGGGCGGCGACGCGCACGTGCTCTACCGTTCGATCAAGCGCGTTTTGGCCCTGCCGCCCGAGACCCGCCTGTTCATGT
GTCACGACTACGGCCCGAACGGCCGCGACATCCGCTGGGAGACCACGGTGGCCGATGAACGGGCGCACAACATTCACGTG
CGCGACGGGGTGAGCGAAGAGGAGTTCGTCGCCATGCGCACAGCCCGCGACGCGACCCTCGACATGCCGCGCCTCATCAT
TCCCTCCATCCAGGTAAACATCCGTGCTGGCGAACTACCGCCGCCCGACGAGACGGGAAAGCGGTTCCTCAAGGTGCCGA
TCAACGGCCTGTGA

Upstream 100 bases:

>100_bases
ATGGCCCTCGCCCGCTGGCTCGCCGGGCGGAGCCATCCCTCCACGGCCCAGGGCACCGATGCCCTGAAGACCCGCCCCTG
AAACAAACGGAGACGCTTCC

Downstream 100 bases:

>100_bases
CCTCTCTGCCCCGATCCGTGTAGCCCCTGCGCGATCGGGGCGCTTTTCTCCGTTCCGGCTGGAGCCCGCCCGTGCCCGCC
TCCCTCCTCACCGATGGCCT

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLPIPHAVDLSVKPEVTAFFDAPTNTVSYVVKDPQSNACAVIDSVMDIDYAAGRIAFQSADAIIAFIQDHGLRLEWLIET
HAHADHLSAAPYIQRTLGGQMGIGENITIVQETFGKIFNEGTEFQRDGSQFDRLFKDGDTYRIGSMTAFAMHTPGHTPAC
MTHVIGNAAFVGDTLFMPDGGTARADFPGGDAHVLYRSIKRVLALPPETRLFMCHDYGPNGRDIRWETTVADERAHNIHV
RDGVSEEEFVAMRTARDATLDMPRLIIPSIQVNIRAGELPPPDETGKRFLKVPINGL

Sequences:

>Translated_297_residues
MLPIPHAVDLSVKPEVTAFFDAPTNTVSYVVKDPQSNACAVIDSVMDIDYAAGRIAFQSADAIIAFIQDHGLRLEWLIET
HAHADHLSAAPYIQRTLGGQMGIGENITIVQETFGKIFNEGTEFQRDGSQFDRLFKDGDTYRIGSMTAFAMHTPGHTPAC
MTHVIGNAAFVGDTLFMPDGGTARADFPGGDAHVLYRSIKRVLALPPETRLFMCHDYGPNGRDIRWETTVADERAHNIHV
RDGVSEEEFVAMRTARDATLDMPRLIIPSIQVNIRAGELPPPDETGKRFLKVPINGL
>Mature_297_residues
MLPIPHAVDLSVKPEVTAFFDAPTNTVSYVVKDPQSNACAVIDSVMDIDYAAGRIAFQSADAIIAFIQDHGLRLEWLIET
HAHADHLSAAPYIQRTLGGQMGIGENITIVQETFGKIFNEGTEFQRDGSQFDRLFKDGDTYRIGSMTAFAMHTPGHTPAC
MTHVIGNAAFVGDTLFMPDGGTARADFPGGDAHVLYRSIKRVLALPPETRLFMCHDYGPNGRDIRWETTVADERAHNIHV
RDGVSEEEFVAMRTARDATLDMPRLIIPSIQVNIRAGELPPPDETGKRFLKVPINGL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=266, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538952, Length=272, Percent_Identity=25.3676470588235, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330176, Length=269, Percent_Identity=27.5092936802974, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32686; Mature: 32686

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPIPHAVDLSVKPEVTAFFDAPTNTVSYVVKDPQSNACAVIDSVMDIDYAAGRIAFQSA
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECC
DAIIAFIQDHGLRLEWLIETHAHADHLSAAPYIQRTLGGQMGIGENITIVQETFGKIFNE
CEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCEEHHHHHHHHHHCC
GTEFQRDGSQFDRLFKDGDTYRIGSMTAFAMHTPGHTPACMTHVIGNAAFVGDTLFMPDG
CCCHHCCHHHHHHHHHCCCCEEECCEEEEEEECCCCCHHHHHHHHCCEEEECCEEECCCC
GTARADFPGGDAHVLYRSIKRVLALPPETRLFMCHDYGPNGRDIRWETTVADERAHNIHV
CCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEE
RDGVSEEEFVAMRTARDATLDMPRLIIPSIQVNIRAGELPPPDETGKRFLKVPINGL
CCCCCHHHHEEHHHCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MLPIPHAVDLSVKPEVTAFFDAPTNTVSYVVKDPQSNACAVIDSVMDIDYAAGRIAFQSA
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECC
DAIIAFIQDHGLRLEWLIETHAHADHLSAAPYIQRTLGGQMGIGENITIVQETFGKIFNE
CEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCEEHHHHHHHHHHCC
GTEFQRDGSQFDRLFKDGDTYRIGSMTAFAMHTPGHTPACMTHVIGNAAFVGDTLFMPDG
CCCHHCCHHHHHHHHHCCCCEEECCEEEEEEECCCCCHHHHHHHHCCEEEECCEEECCCC
GTARADFPGGDAHVLYRSIKRVLALPPETRLFMCHDYGPNGRDIRWETTVADERAHNIHV
CCEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEE
RDGVSEEEFVAMRTARDATLDMPRLIIPSIQVNIRAGELPPPDETGKRFLKVPINGL
CCCCCHHHHEEHHHCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]