Click here to switch to the map view.

The map label for this gene is folB [H]

Identifier: 158423436

GI number: 158423436

Start: 2073223

End: 2073717

Strand: Reverse

Name: folB [H]

Synonym: AZC_1812

Alternate gene names: 158423436

Gene position: 2073717-2073223 (Counterclockwise)

Preceding gene: 158423437

Following gene: 158423435

Centisome position: 38.62

GC content: 70.3

Gene sequence:

>495_bases
ATGACGGAAGGGACTGGCCGCCCACCGGCGGCCGCTGTCCCGTTGCGCGAGGCGTCCATGTCCGCTCCCGATCCCGAAGC
CTTCCCGAGCCCCCAAGAGAGCAGCGCCCCGCAGGCCGCCCCCCGTCCCCGGCGCAACGACCGGCTGTTCCTGCGCGACC
TGCCCTTCTTCGCCCGCCACGGCGTGCATCCCGAGGAGCAGGTGCTCGGCCAGCGCTTCATCGTGGATGCGGACTGGTGG
CTCGACACCCGGCCCGCCGCCTGGGCCGACGATGCCCATCTCACCGTCTCCTATCAGGACGTTTACACCCACATCAAAGC
GGTGGTGGAGGACGACACGGTGCGCCTGATCGAGACGCTCGCCGAGCGCATCGCCACCCGCCTCCTCGACCATTTCCCGC
TCATCGAGCAGGTGCGGATCGCGGTGCGCAAGCCGGGAGCGCCCATCACCGGCGTGTTCGGGGATGTGGGCGTCGACATC
ACCCGCGGCCGTTGA

Upstream 100 bases:

>100_bases
TCAATCCCGTGGCCTTCCTGCCGGATTTCATCCGCAACGGGCGCCCGCCCCAGATGCCCCATCTGCCGCAACCGGTTGCC
ATCGAGCTCAAATTGCGCGC

Downstream 100 bases:

>100_bases
GCCGCCCCACCGCCGCCACAGCCGCATTTTATGGCCGGGCGAGGCGTGACCTTCTGCCCGGCTTGGGCCATAAGGACGCC
GTCCGAACGGTAAAAGGAGA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTEGTGRPPAAAVPLREASMSAPDPEAFPSPQESSAPQAAPRPRRNDRLFLRDLPFFARHGVHPEEQVLGQRFIVDADWW
LDTRPAAWADDAHLTVSYQDVYTHIKAVVEDDTVRLIETLAERIATRLLDHFPLIEQVRIAVRKPGAPITGVFGDVGVDI
TRGR

Sequences:

>Translated_164_residues
MTEGTGRPPAAAVPLREASMSAPDPEAFPSPQESSAPQAAPRPRRNDRLFLRDLPFFARHGVHPEEQVLGQRFIVDADWW
LDTRPAAWADDAHLTVSYQDVYTHIKAVVEDDTVRLIETLAERIATRLLDHFPLIEQVRIAVRKPGAPITGVFGDVGVDI
TRGR
>Mature_163_residues
TEGTGRPPAAAVPLREASMSAPDPEAFPSPQESSAPQAAPRPRRNDRLFLRDLPFFARHGVHPEEQVLGQRFIVDADWWL
DTRPAAWADDAHLTVSYQDVYTHIKAVVEDDTVRLIETLAERIATRLLDHFPLIEQVRIAVRKPGAPITGVFGDVGVDIT
RGR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 18252; Mature: 18121

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGTGRPPAAAVPLREASMSAPDPEAFPSPQESSAPQAAPRPRRNDRLFLRDLPFFARH
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHC
GVHPEEQVLGQRFIVDADWWLDTRPAAWADDAHLTVSYQDVYTHIKAVVEDDTVRLIETL
CCCHHHHHHCHHEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHH
AERIATRLLDHFPLIEQVRIAVRKPGAPITGVFGDVGVDITRGR
HHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCCCCEEEECCC
>Mature Secondary Structure 
TEGTGRPPAAAVPLREASMSAPDPEAFPSPQESSAPQAAPRPRRNDRLFLRDLPFFARH
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHC
GVHPEEQVLGQRFIVDADWWLDTRPAAWADDAHLTVSYQDVYTHIKAVVEDDTVRLIETL
CCCHHHHHHCHHEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHH
AERIATRLLDHFPLIEQVRIAVRKPGAPITGVFGDVGVDITRGR
HHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]