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The map label for this gene is fbp

Identifier: 158423435

GI number: 158423435

Start: 2072130

End: 2073116

Strand: Reverse

Name: fbp

Synonym: AZC_1811

Alternate gene names: 158423435

Gene position: 2073116-2072130 (Counterclockwise)

Preceding gene: 158423436

Following gene: 158423434

Centisome position: 38.61

GC content: 68.49

Gene sequence:

>987_bases
GTGAGCGAGGTGACCCTGCAGGCCTTCCTGGACGACTGGGCCGGTGCCGATCCGCTGCGGTGCGCCGTGGCCGCCACCGT
GGAGCGTCTGGCCGAGGCCGGCGTCTCGATCGCCGAACTCGTGGCCCGTGGCCCCCTCGCCGAGGATTTCGGCAAGGTGC
GCGGCGACGAGGCCAATGCCGGCGGCGACGCCCAGAAGGAACTGGACGTGATCGCCGAGGAAGAACTGGTGGACGCGCTC
GGCCGCGCCCCGGTGGCCTTCCTCGCCTCCGAGGAGAGCGAGACGCCAATCCCGCTCGATCCGCACGGCCGCGTGGTGGT
GGCGGTGGACCCGCTCGACGGCTCCTCCAACATCGACACCAACGTCTCCATCGGCACCATCTTCTCGATCCTGCCCTACG
ACCTGGAACAGCATCCGGACCCGGCCGCAGCGCTGCTCCAGCCCGGCTCGGCGCAGATCGCAGCCGGCTTCCTGGTCTAT
GGTCCGGCAACCATCCTTGTCTCCTCGCTCGGCCAGGGCACGCAGGTGTTCGTGTTCGACCACGACACCGCGACCTTCAT
CCTCGCCCGCGAGAAGGTGGAGATCCCCGCCGCGACCAAGGAATACGGCATCAACCAGTCGAACGTGCGCCACTGGGCCA
AGGCCACGCAGCGCTATATCGACGACTGCCTCGCCGGCAAGGACGGCCCGCGTGGCAAGGACTTCAACATGCGCTGGGTG
GGCTCGCTGGTGGCGGATGCCTTCCGCATCTTCACCCGCGGCGGCGTCTATCTCTATCCGGGCGACAGCCGGAAGGGCTA
TGCGGACGGCCGCCTGCGCCTGATCTATGAGGCGAACCCCATCGCCTTTGTGACCGAGCAGGCGGGCGGCGCGGCCACCG
ACGGCACCACCCGCATCCTCGACATCCAGCCCAAGCAGATCCACCAGCGCATCCCGCTGGTGTTCGGCTCGCGCGAGGAA
GTCGCGCACATCGCCAGCTATTACTGA

Upstream 100 bases:

>100_bases
CCACCGCCGCCACAGCCGCATTTTATGGCCGGGCGAGGCGTGACCTTCTGCCCGGCTTGGGCCATAAGGACGCCGTCCGA
ACGGTAAAAGGAGAGACGCG

Downstream 100 bases:

>100_bases
ACGCGCAAAGCACACCCATATGCGGGAGGCCATGAGCCTCCCGCTGCTGTTTCTCGGAGCCCCATCATGACCGGTCCCCT
CATCGCCCCCTCCATCCTCG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSEVTLQAFLDDWAGADPLRCAVAATVERLAEAGVSIAELVARGPLAEDFGKVRGDEANAGGDAQKELDVIAEEELVDAL
GRAPVAFLASEESETPIPLDPHGRVVVAVDPLDGSSNIDTNVSIGTIFSILPYDLEQHPDPAAALLQPGSAQIAAGFLVY
GPATILVSSLGQGTQVFVFDHDTATFILAREKVEIPAATKEYGINQSNVRHWAKATQRYIDDCLAGKDGPRGKDFNMRWV
GSLVADAFRIFTRGGVYLYPGDSRKGYADGRLRLIYEANPIAFVTEQAGGAATDGTTRILDIQPKQIHQRIPLVFGSREE
VAHIASYY

Sequences:

>Translated_328_residues
MSEVTLQAFLDDWAGADPLRCAVAATVERLAEAGVSIAELVARGPLAEDFGKVRGDEANAGGDAQKELDVIAEEELVDAL
GRAPVAFLASEESETPIPLDPHGRVVVAVDPLDGSSNIDTNVSIGTIFSILPYDLEQHPDPAAALLQPGSAQIAAGFLVY
GPATILVSSLGQGTQVFVFDHDTATFILAREKVEIPAATKEYGINQSNVRHWAKATQRYIDDCLAGKDGPRGKDFNMRWV
GSLVADAFRIFTRGGVYLYPGDSRKGYADGRLRLIYEANPIAFVTEQAGGAATDGTTRILDIQPKQIHQRIPLVFGSREE
VAHIASYY
>Mature_327_residues
SEVTLQAFLDDWAGADPLRCAVAATVERLAEAGVSIAELVARGPLAEDFGKVRGDEANAGGDAQKELDVIAEEELVDALG
RAPVAFLASEESETPIPLDPHGRVVVAVDPLDGSSNIDTNVSIGTIFSILPYDLEQHPDPAAALLQPGSAQIAAGFLVYG
PATILVSSLGQGTQVFVFDHDTATFILAREKVEIPAATKEYGINQSNVRHWAKATQRYIDDCLAGKDGPRGKDFNMRWVG
SLVADAFRIFTRGGVYLYPGDSRKGYADGRLRLIYEANPIAFVTEQAGGAATDGTTRILDIQPKQIHQRIPLVFGSREEV
AHIASYY

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=289, Percent_Identity=39.1003460207612, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI189083692, Length=307, Percent_Identity=37.4592833876222, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI16579888, Length=307, Percent_Identity=37.4592833876222, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI1790679, Length=276, Percent_Identity=42.3913043478261, Blast_Score=213, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17508131, Length=297, Percent_Identity=38.7205387205387, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323409, Length=270, Percent_Identity=38.1481481481481, Blast_Score=175, Evalue=9e-45,
Organism=Drosophila melanogaster, GI45550998, Length=274, Percent_Identity=38.6861313868613, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI19921562, Length=274, Percent_Identity=38.6861313868613, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_AZOC5 (A8I541)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524727.1
- ProteinModelPortal:   A8I541
- SMR:   A8I541
- GeneID:   5691946
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1811
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- ProtClustDB:   CLSK980045
- BioCyc:   ACAU438753:AZC_1811-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 35195; Mature: 35064

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00124 FBPASE

Important sites: BINDING 205-205

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVTLQAFLDDWAGADPLRCAVAATVERLAEAGVSIAELVARGPLAEDFGKVRGDEANA
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCCC
GGDAQKELDVIAEEELVDALGRAPVAFLASEESETPIPLDPHGRVVVAVDPLDGSSNIDT
CCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
NVSIGTIFSILPYDLEQHPDPAAALLQPGSAQIAAGFLVYGPATILVSSLGQGTQVFVFD
CCCHHHHHHHCCCCHHCCCCCHHHHCCCCCCCEEEEEEEECHHHHHHHHCCCCCEEEEEE
HDTATFILAREKVEIPAATKEYGINQSNVRHWAKATQRYIDDCLAGKDGPRGKDFNMRWV
CCCEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
GSLVADAFRIFTRGGVYLYPGDSRKGYADGRLRLIYEANPIAFVTEQAGGAATDGTTRIL
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCEEEE
DIQPKQIHQRIPLVFGSREEVAHIASYY
ECCHHHHHHHCCEEECCHHHHHHHHHCC
>Mature Secondary Structure 
SEVTLQAFLDDWAGADPLRCAVAATVERLAEAGVSIAELVARGPLAEDFGKVRGDEANA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCCC
GGDAQKELDVIAEEELVDALGRAPVAFLASEESETPIPLDPHGRVVVAVDPLDGSSNIDT
CCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
NVSIGTIFSILPYDLEQHPDPAAALLQPGSAQIAAGFLVYGPATILVSSLGQGTQVFVFD
CCCHHHHHHHCCCCHHCCCCCHHHHCCCCCCCEEEEEEEECHHHHHHHHCCCCCEEEEEE
HDTATFILAREKVEIPAATKEYGINQSNVRHWAKATQRYIDDCLAGKDGPRGKDFNMRWV
CCCEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
GSLVADAFRIFTRGGVYLYPGDSRKGYADGRLRLIYEANPIAFVTEQAGGAATDGTTRIL
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCEEEE
DIQPKQIHQRIPLVFGSREEVAHIASYY
ECCHHHHHHHCCEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA