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The map label for this gene is crt [H]

Identifier: 158423432

GI number: 158423432

Start: 2068777

End: 2069571

Strand: Reverse

Name: crt [H]

Synonym: AZC_1808

Alternate gene names: 158423432

Gene position: 2069571-2068777 (Counterclockwise)

Preceding gene: 158423433

Following gene: 158423431

Centisome position: 38.54

GC content: 67.8

Gene sequence:

>795_bases
ATGACATCGACCCCGCCCCTCTCGCTGGACGCCGGCACCACCCGCCTCGCCATTGGCGACGGCATCGCCACCCTTACCTT
CGACCGTCCCGCGGCACGCAACGCCATGACCTGGCGGATGTATGAGGAGCTTTACGCCGCCTGCCGCGAGATCTTGGCGC
GCACCGACGAGATCAAGGTGGCCGTGCTGCGCGGCGCCGGCGGCAAGGCCTTCGTCGCCGGGACGGACATCGAGCAGTTC
CGCGATTTTTCCGGGCAGGACGGCGTTGCCTACGAAGCGCGGGTGGAGACCTATGTGAGCGCGCTTGAGGCCCTGCCCAT
GCCGACCCTCGCGGTAGTCGAGGGCTGGGCGGTAGGCGGCGGCTTCATCCTTGCCAATTCCTGCGATCTCAGGATCGCCA
CGCCCGGCAGCCGGTTCGGTGCCCCTATTGCGCGGACGCTCGGCAACGGGCTTTCGGCCGGCAATCTGCGCCGCCTCACG
TCGACACTGGGCGTCGGCCTCGTGAAGCGCATGCTCATGCTCGCCGAAATGCCGGCGGTGGAAACCTTGCCGCCCGGCTA
TGCGGAAATCGTCCCGCCCGAGGCGCTGGAGGCAAGGCTGGTCGAGGTCTGTACGCAGCTGAAGGGCCATGCCCCTCTCA
CCATGCAGACGGCCAAGGAAGCCCTGCGGCGTCTCGCCACCGAACTGCAGCCCTCGGACTCGGATCTGATCCGCAAGGTC
TATGGCAGTGCCGACTTCAAGGAGGGCATCGCGTCCTTCCTCGAAAAGCGGCGGCCGGACTGGCGCGGCCGCTGA

Upstream 100 bases:

>100_bases
CGAATATCCCCGCTACGTTTCCTTCACCGACGCGCTGCCCATGACGGCGACCGGCAAGATCCTGCGCCGCGAGCTGCGCC
GCCTCGGTTGAGGAAACGCC

Downstream 100 bases:

>100_bases
CCGGCGGAATCATCCGCCGGTGAGGTTGCCCCCCTGAACCTCACCGGCAGGATGCGCCTGACCGGCGTCCAGACCATCAC
GCGGGAATGGTCCAATGGCC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTSTPPLSLDAGTTRLAIGDGIATLTFDRPAARNAMTWRMYEELYAACREILARTDEIKVAVLRGAGGKAFVAGTDIEQF
RDFSGQDGVAYEARVETYVSALEALPMPTLAVVEGWAVGGGFILANSCDLRIATPGSRFGAPIARTLGNGLSAGNLRRLT
STLGVGLVKRMLMLAEMPAVETLPPGYAEIVPPEALEARLVEVCTQLKGHAPLTMQTAKEALRRLATELQPSDSDLIRKV
YGSADFKEGIASFLEKRRPDWRGR

Sequences:

>Translated_264_residues
MTSTPPLSLDAGTTRLAIGDGIATLTFDRPAARNAMTWRMYEELYAACREILARTDEIKVAVLRGAGGKAFVAGTDIEQF
RDFSGQDGVAYEARVETYVSALEALPMPTLAVVEGWAVGGGFILANSCDLRIATPGSRFGAPIARTLGNGLSAGNLRRLT
STLGVGLVKRMLMLAEMPAVETLPPGYAEIVPPEALEARLVEVCTQLKGHAPLTMQTAKEALRRLATELQPSDSDLIRKV
YGSADFKEGIASFLEKRRPDWRGR
>Mature_263_residues
TSTPPLSLDAGTTRLAIGDGIATLTFDRPAARNAMTWRMYEELYAACREILARTDEIKVAVLRGAGGKAFVAGTDIEQFR
DFSGQDGVAYEARVETYVSALEALPMPTLAVVEGWAVGGGFILANSCDLRIATPGSRFGAPIARTLGNGLSAGNLRRLTS
TLGVGLVKRMLMLAEMPAVETLPPGYAEIVPPEALEARLVEVCTQLKGHAPLTMQTAKEALRRLATELQPSDSDLIRKVY
GSADFKEGIASFLEKRRPDWRGR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=26.984126984127, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI31542718, Length=262, Percent_Identity=27.4809160305344, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787659, Length=257, Percent_Identity=32.6848249027237, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=29.6875, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=30.1587301587302, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=30.8880308880309, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=27.3809523809524, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=26.8482490272374, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=159, Percent_Identity=27.6729559748428, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=30.8, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=30.8, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=27.1653543307087, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28442; Mature: 28311

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPPLSLDAGTTRLAIGDGIATLTFDRPAARNAMTWRMYEELYAACREILARTDEIKV
CCCCCCCEECCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
AVLRGAGGKAFVAGTDIEQFRDFSGQDGVAYEARVETYVSALEALPMPTLAVVEGWAVGG
EEEECCCCCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCEECCC
GFILANSCDLRIATPGSRFGAPIARTLGNGLSAGNLRRLTSTLGVGLVKRMLMLAEMPAV
CEEEECCCCEEEECCCCHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
ETLPPGYAEIVPPEALEARLVEVCTQLKGHAPLTMQTAKEALRRLATELQPSDSDLIRKV
CCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
YGSADFKEGIASFLEKRRPDWRGR
HCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSTPPLSLDAGTTRLAIGDGIATLTFDRPAARNAMTWRMYEELYAACREILARTDEIKV
CCCCCCEECCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
AVLRGAGGKAFVAGTDIEQFRDFSGQDGVAYEARVETYVSALEALPMPTLAVVEGWAVGG
EEEECCCCCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCEECCC
GFILANSCDLRIATPGSRFGAPIARTLGNGLSAGNLRRLTSTLGVGLVKRMLMLAEMPAV
CEEEECCCCEEEECCCCHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
ETLPPGYAEIVPPEALEARLVEVCTQLKGHAPLTMQTAKEALRRLATELQPSDSDLIRKV
CCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
YGSADFKEGIASFLEKRRPDWRGR
HCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]