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The map label for this gene is actP [H]

Identifier: 158423267

GI number: 158423267

Start: 1881580

End: 1883448

Strand: Direct

Name: actP [H]

Synonym: AZC_1643

Alternate gene names: 158423267

Gene position: 1881580-1883448 (Clockwise)

Preceding gene: 158423266

Following gene: 158423268

Centisome position: 35.04

GC content: 71.64

Gene sequence:

>1869_bases
ATGAGGGGAGGGCGCATGGATCACGCGCAGGAAAGCCGGCTGAAGACCCTGCTGCTGCTCCTCGCGCTTGGGGCGCTCGC
GTGTGGGCTCGCCGTGCGCCTCGGCGGATGGGAGCGGGCCGCCGCCGTCGTGTGGAGCGTGGGGACGATCCCGGTGCTGC
TGGCGCTGCTCCTGGAGATCCTGCGCAGCCTGCGGCGGGGGGAAATCGGGCTCGATATCGTCGCGGCGCTCTCCATGTCC
TCCGCGCTTCTGGTCGGCGAGGCTCTCGCCGCCTGTGTGGTCGCGGTGATGTATTCCGGCGGCACCTTCCTGGAGAGTTT
CGCGGAAGGCCGCGCGCGTCGGGACATGCGTGACCTCCTCGCCCGCGTGCCCCGCAGCGCCACCCGTCACCGTGCGGGCG
CGCTGGAGGACATTCCGCTCGATGCCATCACGCCGGGGGACCGCCTGCTGATCCGGCAGGGGGACGTGGTGCCGGTGGAC
GGCACCATCGCCTCCGACACCGCCTTTCTCGATGCCTCCGCCTTGACCGGCGAGGCCCTGCCGGTCCGCCTCGCGCGCGA
TGAAGCCGCCATGAGCGGTTCCAACAATGCGGGCGAAGCGTTCGACCTCATCGCCACCCGGCCGGCACGCGACAGCACAT
ACGCGGGCATCGTGCGGCTGGTGGAGGAGGCGCAGCGCTCCAAGGCACCCATGGCGCGGCTCGCGGACCAGTGGTCGCTG
GGCTTCCTCGCCGTGACGGTGGCTCTGGCGGTGGCGGCATGGTGGTTCACCGGCGATCCGGTCCGGGCCGTGGCCGTGCT
GGTCGTGGCGACGCCGTGTCCGCTGATCCTCGCCGTGCCGGTTGCCCTTGTGGCAGGCCTGTCCCGCGCTGCCCATTTCG
GCGTTCTCATCAAGGGCGCGGGGCCACTGGAGGCCATGGCCCGGACGCGGACGCTGATCCTCGACAAGACCGGCACGCTC
ACCGAGGGACGGCCGCGGATCGTCTCCGTCCTCAGTCATGACGGCACCGCGGCGGACGACATTCTGCGTCTTGCGGCCGC
GCTCGATCAGGCGACCAAGCACCCCGTGGCGCAGGCCATCGTGGCGGCGGCGCGCGAGCGCGGGCTCACGCTCAGCGTGC
CATCCTGCGTCGTGGAGACGCCGGGTGAGGGGCTGTCGGGGCAGGTGGAGGGGCGAACCGTGCTCGTCGGCGGGGATGGC
TTCGTCACCGCGCGCGTGGGCCAGGGGGCGGCCCGGATCGAACTCCCTGCCGGTTCTGTTCTGGTGGCGGTGGGGCTCGA
TGGGCGGCTGGCCGGACATCTCGTCATGGCCGATCCGCTACGGGCTGGTACGCGCGACATGCTGGACGGGCTGCGCCGGG
AAGGAGTGGAGCGCATCCTGCTTGCCACCGGCGATCGTCGGGAGGTGGCGGAGAGCGTGACGCAGGGGCTTGGCCTCGAC
GGCATCCGCGCGGGGCTGACGCCGGACCAGAAGGTGCTGCTGGTGCTCTCCGAGCGCAAGCGCGGTCCGGTGATGATGGT
CGGCGACGGGGTGAACGACGCGCCCGCGCTTGCCGCGGCCGACGTGGGCGTCGCGATGGGCGCACGGGGCGCCGCGGCGT
CCGCCGAGGCGGCCGATGTGGTGCTGTTGGTGGACCGGGTGGATCGTCTGGTGCCCGGCATCGGAATTGCCCGTGGCGCG
CGGCGGATCGCGATGGAAAGCGTCGTTGCGGGTATCGGCCTGTCGGTCATCGGCATGGTGGCGGCGGCGCTCGGTCATCT
CTCACCGGTGCAGGGGGCACTGATCCAGGAGGTCATCGATGTCGCCGTAATCCTGAACGCACTGCGGGCCCTTCGCCTCT
CCCCGAAGGGAAAGGGGGCGCAGGCCTGA

Upstream 100 bases:

>100_bases
TCTCGCCACGGGAAAGCAGCGCGGGTGGCGGTGGGCCGCCGGACATCGCCGCAGGGACCTGTCGCCCCGGTGCTGAACGC
ACCGGCTTCCGGCACCGGTC

Downstream 100 bases:

>100_bases
CGCAGCGTTGCAGCATGTCGGCACCCGGGTGTGGCCCCGCGGAATGGGGCGACCTCCAAATTTCGGGGCTTCCCCCGTGA
TGCGTGGGGCTGTGCGTGCG

Product: cation transport P-type ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MRGGRMDHAQESRLKTLLLLLALGALACGLAVRLGGWERAAAVVWSVGTIPVLLALLLEILRSLRRGEIGLDIVAALSMS
SALLVGEALAACVVAVMYSGGTFLESFAEGRARRDMRDLLARVPRSATRHRAGALEDIPLDAITPGDRLLIRQGDVVPVD
GTIASDTAFLDASALTGEALPVRLARDEAAMSGSNNAGEAFDLIATRPARDSTYAGIVRLVEEAQRSKAPMARLADQWSL
GFLAVTVALAVAAWWFTGDPVRAVAVLVVATPCPLILAVPVALVAGLSRAAHFGVLIKGAGPLEAMARTRTLILDKTGTL
TEGRPRIVSVLSHDGTAADDILRLAAALDQATKHPVAQAIVAAARERGLTLSVPSCVVETPGEGLSGQVEGRTVLVGGDG
FVTARVGQGAARIELPAGSVLVAVGLDGRLAGHLVMADPLRAGTRDMLDGLRREGVERILLATGDRREVAESVTQGLGLD
GIRAGLTPDQKVLLVLSERKRGPVMMVGDGVNDAPALAAADVGVAMGARGAAASAEAADVVLLVDRVDRLVPGIGIARGA
RRIAMESVVAGIGLSVIGMVAAALGHLSPVQGALIQEVIDVAVILNALRALRLSPKGKGAQA

Sequences:

>Translated_622_residues
MRGGRMDHAQESRLKTLLLLLALGALACGLAVRLGGWERAAAVVWSVGTIPVLLALLLEILRSLRRGEIGLDIVAALSMS
SALLVGEALAACVVAVMYSGGTFLESFAEGRARRDMRDLLARVPRSATRHRAGALEDIPLDAITPGDRLLIRQGDVVPVD
GTIASDTAFLDASALTGEALPVRLARDEAAMSGSNNAGEAFDLIATRPARDSTYAGIVRLVEEAQRSKAPMARLADQWSL
GFLAVTVALAVAAWWFTGDPVRAVAVLVVATPCPLILAVPVALVAGLSRAAHFGVLIKGAGPLEAMARTRTLILDKTGTL
TEGRPRIVSVLSHDGTAADDILRLAAALDQATKHPVAQAIVAAARERGLTLSVPSCVVETPGEGLSGQVEGRTVLVGGDG
FVTARVGQGAARIELPAGSVLVAVGLDGRLAGHLVMADPLRAGTRDMLDGLRREGVERILLATGDRREVAESVTQGLGLD
GIRAGLTPDQKVLLVLSERKRGPVMMVGDGVNDAPALAAADVGVAMGARGAAASAEAADVVLLVDRVDRLVPGIGIARGA
RRIAMESVVAGIGLSVIGMVAAALGHLSPVQGALIQEVIDVAVILNALRALRLSPKGKGAQA
>Mature_622_residues
MRGGRMDHAQESRLKTLLLLLALGALACGLAVRLGGWERAAAVVWSVGTIPVLLALLLEILRSLRRGEIGLDIVAALSMS
SALLVGEALAACVVAVMYSGGTFLESFAEGRARRDMRDLLARVPRSATRHRAGALEDIPLDAITPGDRLLIRQGDVVPVD
GTIASDTAFLDASALTGEALPVRLARDEAAMSGSNNAGEAFDLIATRPARDSTYAGIVRLVEEAQRSKAPMARLADQWSL
GFLAVTVALAVAAWWFTGDPVRAVAVLVVATPCPLILAVPVALVAGLSRAAHFGVLIKGAGPLEAMARTRTLILDKTGTL
TEGRPRIVSVLSHDGTAADDILRLAAALDQATKHPVAQAIVAAARERGLTLSVPSCVVETPGEGLSGQVEGRTVLVGGDG
FVTARVGQGAARIELPAGSVLVAVGLDGRLAGHLVMADPLRAGTRDMLDGLRREGVERILLATGDRREVAESVTQGLGLD
GIRAGLTPDQKVLLVLSERKRGPVMMVGDGVNDAPALAAADVGVAMGARGAAASAEAADVVLLVDRVDRLVPGIGIARGA
RRIAMESVVAGIGLSVIGMVAAALGHLSPVQGALIQEVIDVAVILNALRALRLSPKGKGAQA

Specific function: Involved in copper efflux [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=681, Percent_Identity=27.6064610866373, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI55743073, Length=497, Percent_Identity=30.5835010060362, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI115529486, Length=583, Percent_Identity=26.9296740994854, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI118498343, Length=255, Percent_Identity=24.3137254901961, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789879, Length=624, Percent_Identity=31.7307692307692, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1786691, Length=540, Percent_Identity=33.7037037037037, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI1786914, Length=542, Percent_Identity=27.6752767527675, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17556548, Length=576, Percent_Identity=28.125, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI32566766, Length=74, Percent_Identity=50, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17557770, Length=74, Percent_Identity=50, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557486, Length=74, Percent_Identity=50, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559224, Length=180, Percent_Identity=29.4444444444444, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=498, Percent_Identity=28.1124497991968, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319772, Length=463, Percent_Identity=27.2138228941685, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6321430, Length=579, Percent_Identity=24.8704663212435, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325221, Length=581, Percent_Identity=24.7848537005164, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321271, Length=209, Percent_Identity=29.6650717703349, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221329854, Length=369, Percent_Identity=28.1842818428184, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24668704, Length=578, Percent_Identity=23.0103806228374, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24668708, Length=578, Percent_Identity=23.0103806228374, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24668696, Length=578, Percent_Identity=23.0103806228374, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281366617, Length=578, Percent_Identity=23.0103806228374, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161085803, Length=578, Percent_Identity=23.0103806228374, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281366676, Length=96, Percent_Identity=40.625, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR001366
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 64133; Mature: 64133

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGGRMDHAQESRLKTLLLLLALGALACGLAVRLGGWERAAAVVWSVGTIPVLLALLLEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRSLRRGEIGLDIVAALSMSSALLVGEALAACVVAVMYSGGTFLESFAEGRARRDMRDLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ARVPRSATRHRAGALEDIPLDAITPGDRLLIRQGDVVPVDGTIASDTAFLDASALTGEAL
HHCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCEEEHHHCCCCCC
PVRLARDEAAMSGSNNAGEAFDLIATRPARDSTYAGIVRLVEEAQRSKAPMARLADQWSL
EEEEECCHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GFLAVTVALAVAAWWFTGDPVRAVAVLVVATPCPLILAVPVALVAGLSRAAHFGVLIKGA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECC
GPLEAMARTRTLILDKTGTLTEGRPRIVSVLSHDGTAADDILRLAAALDQATKHPVAQAI
CCHHHHHHHHEEEEECCCCCCCCCCCEEHEECCCCCCHHHHHHHHHHHHHHHCCHHHHHH
VAAARERGLTLSVPSCVVETPGEGLSGQVEGRTVLVGGDGFVTARVGQGAARIELPAGSV
HHHHHHCCCEEECCCCEEECCCCCCCCEECCEEEEECCCCEEEEEECCCCEEEECCCCCE
LVAVGLDGRLAGHLVMADPLRAGTRDMLDGLRREGVERILLATGDRREVAESVTQGLGLD
EEEEECCCCEECCEEEECCCCCCHHHHHHHHHHHCHHEEECCCCCHHHHHHHHHHCCCCC
GIRAGLTPDQKVLLVLSERKRGPVMMVGDGVNDAPALAAADVGVAMGARGAAASAEAADV
CHHCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
VLLVDRVDRLVPGIGIARGARRIAMESVVAGIGLSVIGMVAAALGHLSPVQGALIQEVID
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAVILNALRALRLSPKGKGAQA
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRGGRMDHAQESRLKTLLLLLALGALACGLAVRLGGWERAAAVVWSVGTIPVLLALLLEI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRSLRRGEIGLDIVAALSMSSALLVGEALAACVVAVMYSGGTFLESFAEGRARRDMRDLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ARVPRSATRHRAGALEDIPLDAITPGDRLLIRQGDVVPVDGTIASDTAFLDASALTGEAL
HHCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCEEEHHHCCCCCC
PVRLARDEAAMSGSNNAGEAFDLIATRPARDSTYAGIVRLVEEAQRSKAPMARLADQWSL
EEEEECCHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GFLAVTVALAVAAWWFTGDPVRAVAVLVVATPCPLILAVPVALVAGLSRAAHFGVLIKGA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECC
GPLEAMARTRTLILDKTGTLTEGRPRIVSVLSHDGTAADDILRLAAALDQATKHPVAQAI
CCHHHHHHHHEEEEECCCCCCCCCCCEEHEECCCCCCHHHHHHHHHHHHHHHCCHHHHHH
VAAARERGLTLSVPSCVVETPGEGLSGQVEGRTVLVGGDGFVTARVGQGAARIELPAGSV
HHHHHHCCCEEECCCCEEECCCCCCCCEECCEEEEECCCCEEEEEECCCCEEEECCCCCE
LVAVGLDGRLAGHLVMADPLRAGTRDMLDGLRREGVERILLATGDRREVAESVTQGLGLD
EEEEECCCCEECCEEEECCCCCCHHHHHHHHHHHCHHEEECCCCCHHHHHHHHHHCCCCC
GIRAGLTPDQKVLLVLSERKRGPVMMVGDGVNDAPALAAADVGVAMGARGAAASAEAADV
CHHCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
VLLVDRVDRLVPGIGIARGARRIAMESVVAGIGLSVIGMVAAALGHLSPVQGALIQEVID
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAVILNALRALRLSPKGKGAQA
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11936079 [H]