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The map label for this gene is clpX

Identifier: 158423233

GI number: 158423233

Start: 1836232

End: 1837500

Strand: Direct

Name: clpX

Synonym: AZC_1609

Alternate gene names: 158423233

Gene position: 1836232-1837500 (Clockwise)

Preceding gene: 158423232

Following gene: 158423234

Centisome position: 34.2

GC content: 63.83

Gene sequence:

>1269_bases
ATGAGCAAGACCGGCGGCAGCGACAGCAAGAACACGCTTTACTGCTCGTTCTGCGGCAAGAGCCAGCACGAGGTCCGCAA
GCTCATCGCAGGGCCTACGGTCTTCATTTGCGACGAGTGTGTCGAACTCTGCATGGACATCATCCGCGAGGAGAGCAAGT
CCTCCCTGGTGAAGTCCCGCGATGGCATCCCCACCCCGAAGGAGATCCGCAAGGTTCTCGATGACTACGTCATCGGCCAG
GACCATGCGAAGAAGGTCCTCTCGGTGGCGGTGCACAACCACTACAAGCGCCTGAACCACGCCACCAAGCACGGCGATGT
GGAACTGGCCAAGTCCAACATCATGCTCATCGGCCCGACGGGTTCCGGCAAGACGCTGCTGGCCCAGACGCTGGCGCGCA
TCCTGGACGTGCCCTTCACCATGGCCGACGCCACCACGCTGACCGAGGCCGGCTATGTGGGCGAGGATGTGGAGAACATC
ATCCTCAAGCTGCTCCAGGCCGCCGACTACAATGTGGAGCGGGCGCAGCGCGGCATCGTCTACATCGACGAGATCGACAA
GATCAGTCGCAAGTCCGACAACCCGTCCATCACCCGCGACGTCTCGGGCGAGGGCGTGCAGCAGGCCCTGCTGAAGATCA
TGGAAGGCACCGTTGCCTCCGTGCCCCCGCAGGGCGGCCGCAAGCACCCCCAGCAGGAATTCCTGCAGGTGGACACCACC
AACATCCTCTTCATCTGCGGCGGCGCCTTCGCGGGCCTCGACAAGATCATCTCGTCCCGCTCCAAGGGCGGCACCTCCAT
CGGCTTCGGCGCCAAGGTGGCTCCCGTCGAGGAGCGTCGTCCCGGCGAGTTGTTCCGCGAGGTGGAGCCCGAGGATCTGC
TGAAGTACGGCCTCATCCCCGAGTTCATCGGCCGTCTGCCCGTGCTTGCCACGCTCAACGACCTCGACGAGGCGGCGCTC
AAGCAGATCCTGGCCGAGCCGAAGAACGCGCTGGTGAAGCAGTATCAGCGCCTCTTCGAGATGGAGAACGTGGATCTCAC
CATCCATGAGGAAGCGCTGGGCGCCATCGCCCGCAAGGCCATCGAGCGCAAGACGGGCGCGCGCGGCTTGCGCTCGATCA
TGGAAGGAATCCTGCTGGACACCATGTTTGACCTTCCCGGCCTCGAAGGCGTCGAGGAAGTGGTGATCAGCAAGGAAGTG
GTCGAGCAGAATGCGCGCCCGCTCTACATTTACGCGGACCGTGTCGGCGACGCCGGCGCCAGCGCCTGA

Upstream 100 bases:

>100_bases
CTCAGGCGCAGCGTCGCCGGCCCCAACAAGGGTTCCGTCCAGACGGGGAGGGGTCCTGAACAGGACCTGAGCCGGAGGGG
CGGACCGCACGGAGATGAAG

Downstream 100 bases:

>100_bases
CGGGGTTTATCCCGCTTCCTTCCCTCGCGCCGCCGGCGCGGGGGAAACGCCAGAACCTGCCTGTTTCATGAATGTTTCAC
GTGCGGTGTCGGGAGCCTTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQ
DHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIISSRSKGGTSIGFGAKVAPVEERRPGELFREVEPEDLLKYGLIPEFIGRLPVLATLNDLDEAAL
KQILAEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMEGILLDTMFDLPGLEGVEEVVISKEV
VEQNARPLYIYADRVGDAGASA

Sequences:

>Translated_422_residues
MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQ
DHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDKIISSRSKGGTSIGFGAKVAPVEERRPGELFREVEPEDLLKYGLIPEFIGRLPVLATLNDLDEAAL
KQILAEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMEGILLDTMFDLPGLEGVEEVVISKEV
VEQNARPLYIYADRVGDAGASA
>Mature_421_residues
SKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQD
HAKKVLSVAVHNHYKRLNHATKHGDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLDKIISSRSKGGTSIGFGAKVAPVEERRPGELFREVEPEDLLKYGLIPEFIGRLPVLATLNDLDEAALK
QILAEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMEGILLDTMFDLPGLEGVEEVVISKEVV
EQNARPLYIYADRVGDAGASA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=335, Percent_Identity=54.3283582089552, Blast_Score=329, Evalue=4e-90,
Organism=Escherichia coli, GI1786642, Length=405, Percent_Identity=73.8271604938272, Blast_Score=605, Evalue=1e-174,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=45.2830188679245, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=47.1153846153846, Blast_Score=277, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=47.1153846153846, Blast_Score=277, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=411, Percent_Identity=36.4963503649635, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=167, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=419, Percent_Identity=40.5727923627685, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=333, Percent_Identity=49.5495495495495, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24648289, Length=333, Percent_Identity=49.5495495495495, Blast_Score=301, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_AZOC5 (A8HYF4)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524525.1
- ProteinModelPortal:   A8HYF4
- GeneID:   5687768
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1609
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   ACAU438753:AZC_1609-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46141; Mature: 46009

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGIPTPKEIRKVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNIMLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDKIISSRSKGGTSIGFGAKVAPVEERRPGELFREVEPEDLLKYGLIP
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHHCCHHHHHHHCCCH
EFIGRLPVLATLNDLDEAALKQILAEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKA
HHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IERKTGARGLRSIMEGILLDTMFDLPGLEGVEEVVISKEVVEQNARPLYIYADRVGDAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
SA
CC
>Mature Secondary Structure 
SKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGIPTPKEIRKVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNIMLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDKIISSRSKGGTSIGFGAKVAPVEERRPGELFREVEPEDLLKYGLIP
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHHCCHHHHHHHCCCH
EFIGRLPVLATLNDLDEAALKQILAEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKA
HHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IERKTGARGLRSIMEGILLDTMFDLPGLEGVEEVVISKEVVEQNARPLYIYADRVGDAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA