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The map label for this gene is tig

Identifier: 158423231

GI number: 158423231

Start: 1833624

End: 1834973

Strand: Direct

Name: tig

Synonym: AZC_1607

Alternate gene names: 158423231

Gene position: 1833624-1834973 (Clockwise)

Preceding gene: 158423230

Following gene: 158423232

Centisome position: 34.15

GC content: 65.56

Gene sequence:

>1350_bases
ATGCAGGTGACCGAAACCCAGGCCGAGGGCCTCAAGCGCGCCTACACTGTGGTGCTCCCCGCGGCCGAGCTCGACGCCAA
GGCTCAGGATCGCCTGGTCGAGCTCAAGGACAAGGTCCGGATCAACGGCTTCCGCCCCGGCAAGGTGCCGCTGTCCCACC
TCAAGTCGCTGTACGGCAAGTCCGTCATGGCCGAGGTGATCGAGCAGGCCGTGACCGAGGCCAACGGCAAGATCGTCGAG
GACAACGGCCTGCGCCTCGCGCTGCCGCCGAAGGTCGAGCTGCCCCAGGCCGAGGACGAAGTGAAGAGCGTCATCGAGGG
CCAGGCCGACCTCAAGTACACGGTCGAGCTGGAAGTGCTGCCGAAGATCGAGCTCGGCAACTTCAAGGACATCGCCATCG
AGAAGCCCGTCGCCATCGTCACCGATGAAGAGGTGGACGAGATGGTGAAGCGCATTGCCGACGGCAACCGCTCCTTCGAC
GCCAAGGAAGGCGCCGCCGCTTCGGGCGACCGCATCACCGTGGACTTCGTGGGCTCCATCGACGGCGTCCCGTTCGAGGG
CGGCGCTGGCGAGGACGTGCCGGTGGTGATCGGCTCCAACAGCTTCATCCCCGGCTTCGAGGAGCAGCTCATCGGGCTGT
CCGCCGGCGAGGAGCGCACCATCAATGTCACCTTCCCGACGAACTATCTGTCGGCCCAGCTCGCCGGCAAGGATGCGTCC
TTCGCGGTGAAGGCCAAGCAGGTGGAGGCTCCCGGCGAGCTGACCATCGACGACGAGTTCGCCAAGACGCTCGGTCTCGA
GAGCCTCGACAAGCTCAAGGAGAATGTGCGCGAGCGCATCGCCAAGGAGCATGAAGGCGCGACCCGCCAGCGCGTGAAGC
GTCAGCTGCTCGACGCGCTCGACGCCGGCCACAAGTTCGACGTACCCCCGACCCTCGTCTCGCAGGAGTTCGAGGGCGTG
TGGCAGCAGATCCAGACCGATCTGCAGCAGCAGGGCCGCACCTTCGCCGACGAGAGCACGACGGAAGAGGAAGCCCGCGC
CGAATATCAGCGCATTGCCGAGCGCCGCGTGCGCCTTGGCCTGGTTCTTGCGGAGATCGGGGAGCGCAACAATATACAGG
TCACCGACGACGAGGTGACGCGTGCGGTTGTCGAGCGGGCGCGTCAGTTCCCCGGCCAGGAACAGCAGGTGTGGGAATAT
TATCGCCGCAATGCGCAGGCGATGGCGTCCCTGCGTGCGCCCCTGTTCGAGGAGAAGGTCGTCGACTTCCTTCTGGAGCT
CGCCAAGGTGACCGAGAAGCAGGTCAGCCGCGAGGAGCTCTACAAGGAGGAAGAGGAGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
TCCACACCCGTTTCCGCAGGGATGAGGGCGCAGCGCTTCCGCCGCGCCGGACAGATTCGAACCGAACCGCCGTGCGCGGC
TTATGGATGAAGGCAAGACG

Downstream 100 bases:

>100_bases
GTTCAGGCCTCCTTCACCGCTGCCTGCGACGATTTGCGCGCATTCTCCGCGCCGAGGACCAAAAATGCGTGATCCTGTCG
ATACTTATATGAACTACCTC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQVTETQAEGLKRAYTVVLPAAELDAKAQDRLVELKDKVRINGFRPGKVPLSHLKSLYGKSVMAEVIEQAVTEANGKIVE
DNGLRLALPPKVELPQAEDEVKSVIEGQADLKYTVELEVLPKIELGNFKDIAIEKPVAIVTDEEVDEMVKRIADGNRSFD
AKEGAAASGDRITVDFVGSIDGVPFEGGAGEDVPVVIGSNSFIPGFEEQLIGLSAGEERTINVTFPTNYLSAQLAGKDAS
FAVKAKQVEAPGELTIDDEFAKTLGLESLDKLKENVRERIAKEHEGATRQRVKRQLLDALDAGHKFDVPPTLVSQEFEGV
WQQIQTDLQQQGRTFADESTTEEEARAEYQRIAERRVRLGLVLAEIGERNNIQVTDDEVTRAVVERARQFPGQEQQVWEY
YRRNAQAMASLRAPLFEEKVVDFLLELAKVTEKQVSREELYKEEEEKAA

Sequences:

>Translated_449_residues
MQVTETQAEGLKRAYTVVLPAAELDAKAQDRLVELKDKVRINGFRPGKVPLSHLKSLYGKSVMAEVIEQAVTEANGKIVE
DNGLRLALPPKVELPQAEDEVKSVIEGQADLKYTVELEVLPKIELGNFKDIAIEKPVAIVTDEEVDEMVKRIADGNRSFD
AKEGAAASGDRITVDFVGSIDGVPFEGGAGEDVPVVIGSNSFIPGFEEQLIGLSAGEERTINVTFPTNYLSAQLAGKDAS
FAVKAKQVEAPGELTIDDEFAKTLGLESLDKLKENVRERIAKEHEGATRQRVKRQLLDALDAGHKFDVPPTLVSQEFEGV
WQQIQTDLQQQGRTFADESTTEEEARAEYQRIAERRVRLGLVLAEIGERNNIQVTDDEVTRAVVERARQFPGQEQQVWEY
YRRNAQAMASLRAPLFEEKVVDFLLELAKVTEKQVSREELYKEEEEKAA
>Mature_449_residues
MQVTETQAEGLKRAYTVVLPAAELDAKAQDRLVELKDKVRINGFRPGKVPLSHLKSLYGKSVMAEVIEQAVTEANGKIVE
DNGLRLALPPKVELPQAEDEVKSVIEGQADLKYTVELEVLPKIELGNFKDIAIEKPVAIVTDEEVDEMVKRIADGNRSFD
AKEGAAASGDRITVDFVGSIDGVPFEGGAGEDVPVVIGSNSFIPGFEEQLIGLSAGEERTINVTFPTNYLSAQLAGKDAS
FAVKAKQVEAPGELTIDDEFAKTLGLESLDKLKENVRERIAKEHEGATRQRVKRQLLDALDAGHKFDVPPTLVSQEFEGV
WQQIQTDLQQQGRTFADESTTEEEARAEYQRIAERRVRLGLVLAEIGERNNIQVTDDEVTRAVVERARQFPGQEQQVWEY
YRRNAQAMASLRAPLFEEKVVDFLLELAKVTEKQVSREELYKEEEEKAA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=446, Percent_Identity=33.8565022421525, Blast_Score=234, Evalue=9e-63,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_AZOC5 (A8HYF0)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524523.1
- ProteinModelPortal:   A8HYF0
- SMR:   A8HYF0
- GeneID:   5688799
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1607
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   ACAU438753:AZC_1607-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49890; Mature: 49890

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTETQAEGLKRAYTVVLPAAELDAKAQDRLVELKDKVRINGFRPGKVPLSHLKSLYGK
CCCCCHHHHHHHHHHHEEEECHHHCCHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHH
SVMAEVIEQAVTEANGKIVEDNGLRLALPPKVELPQAEDEVKSVIEGQADLKYTVELEVL
HHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEE
PKIELGNFKDIAIEKPVAIVTDEEVDEMVKRIADGNRSFDAKEGAAASGDRITVDFVGSI
CCCCCCCCCCEEECCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
DGVPFEGGAGEDVPVVIGSNSFIPGFEEQLIGLSAGEERTINVTFPTNYLSAQLAGKDAS
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCEEEEEEECCHHHHHHHCCCCCC
FAVKAKQVEAPGELTIDDEFAKTLGLESLDKLKENVRERIAKEHEGATRQRVKRQLLDAL
EEEEEHEECCCCCEEECHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DAGHKFDVPPTLVSQEFEGVWQQIQTDLQQQGRTFADESTTEEEARAEYQRIAERRVRLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LVLAEIGERNNIQVTDDEVTRAVVERARQFPGQEQQVWEYYRRNAQAMASLRAPLFEEKV
HHHHHHCCCCCEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
VDFLLELAKVTEKQVSREELYKEEEEKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQVTETQAEGLKRAYTVVLPAAELDAKAQDRLVELKDKVRINGFRPGKVPLSHLKSLYGK
CCCCCHHHHHHHHHHHEEEECHHHCCHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHH
SVMAEVIEQAVTEANGKIVEDNGLRLALPPKVELPQAEDEVKSVIEGQADLKYTVELEVL
HHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEE
PKIELGNFKDIAIEKPVAIVTDEEVDEMVKRIADGNRSFDAKEGAAASGDRITVDFVGSI
CCCCCCCCCCEEECCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
DGVPFEGGAGEDVPVVIGSNSFIPGFEEQLIGLSAGEERTINVTFPTNYLSAQLAGKDAS
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCEEEEEEECCHHHHHHHCCCCCC
FAVKAKQVEAPGELTIDDEFAKTLGLESLDKLKENVRERIAKEHEGATRQRVKRQLLDAL
EEEEEHEECCCCCEEECHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DAGHKFDVPPTLVSQEFEGVWQQIQTDLQQQGRTFADESTTEEEARAEYQRIAERRVRLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LVLAEIGERNNIQVTDDEVTRAVVERARQFPGQEQQVWEYYRRNAQAMASLRAPLFEEKV
HHHHHHCCCCCEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
VDFLLELAKVTEKQVSREELYKEEEEKAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA