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The map label for this gene is lysR [H]

Identifier: 158423230

GI number: 158423230

Start: 1832359

End: 1833264

Strand: Direct

Name: lysR [H]

Synonym: AZC_1606

Alternate gene names: 158423230

Gene position: 1832359-1833264 (Clockwise)

Preceding gene: 158423227

Following gene: 158423231

Centisome position: 34.12

GC content: 73.07

Gene sequence:

>906_bases
ATGAGCATCGATCTGTCCGACCTCGGCGCCTTCATGGCTGTGGCGCGGGCGCGGGGCTTCCGGGATGCGGCGCGGGTGAG
CGGGGCGAGTCCCTCGGCCCTCAGCGACGCCGTGCGGCGGGTGGAGGCGCAGCTCGGGGTGCGGCTGCTCCACCGCACCA
CCCGCAGCGTTGCCCCCACCGAGGCGGGCGCCCGGCTGATGGAGCGGCTCGGCCCGGCGCTCGGCGAGGTGGAGGCGGCG
CTCGATGTGGTGAACGGGTTCCGGGATCGGCCGGCCGGCACCCTGCGGCTCAATGTGCCGGTGAGCGCGGCGCGGCTCGT
GCTGCCGTCGCTCGTGCCGGATTTCCTGGCCGCCTATCCCGACATCCGGCTGGAGATCACGGCGGAGGATACGTTCGTCG
ATCTTCTGGCGGCGGGCTGTGACGCCGGCATCCGCTATGACGAGCGGCTGGAGCAGGACATGATCGCGGTGCCCATCGGC
CCGCGCACGCAGCGCTTCGCGACGGCGGCGGCGCCGGCCTATCTCGACCGGCGGGGTCGGCCGGCGCATCCGCGCGACCT
GCTCGCCCATGCCTGCCTGCTCGCCCGCTTCAGCAGTGGCGCCATGATGGCCTGGGAGTTCGAGCGGGACGGGGAGGTGG
TGCGCGTCGAGCCCACCGGCCCGCTGCTGGTGAGCGTCGGGGCCGCGACGGAGCTTGCAGTGGAGGCGGCGGTGGCCGGA
ACGGGCATCATTGCTCTGTTCGAGGACTGGCTGCGCCCGCATCTGGACAGCGGCGCGCTGGAGCCCGTGCTGGAGGCGTG
GTGGCCACGCTTCTCGGGGCCCTTCCTTTATTATCCGGGCCGCCGGCTGGTGCCGGCGCCGCTCAGGGCCTTCGTGGATT
TCGTACGGACGCGGCAGGAAGGCTGA

Upstream 100 bases:

>100_bases
GTCTCCGTTGGGTGGCCGAAGGCTCGGCCCCTGAATTAGGCCTTGCCGCCCGCGTCGATAATCCCGCACAGTCCGTACGG
CTTGTGCGGATTTCAGAACA

Downstream 100 bases:

>100_bases
CGCTGGGTCCGTCTGCGGCGGGCGTTGTCCATAAGCCTGCCCTGGTGACGGGTGCTTTTTCTTGCTGCACGGGAAATCGG
GCGTGATATAAGCCCCAACC

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSIDLSDLGAFMAVARARGFRDAARVSGASPSALSDAVRRVEAQLGVRLLHRTTRSVAPTEAGARLMERLGPALGEVEAA
LDVVNGFRDRPAGTLRLNVPVSAARLVLPSLVPDFLAAYPDIRLEITAEDTFVDLLAAGCDAGIRYDERLEQDMIAVPIG
PRTQRFATAAAPAYLDRRGRPAHPRDLLAHACLLARFSSGAMMAWEFERDGEVVRVEPTGPLLVSVGAATELAVEAAVAG
TGIIALFEDWLRPHLDSGALEPVLEAWWPRFSGPFLYYPGRRLVPAPLRAFVDFVRTRQEG

Sequences:

>Translated_301_residues
MSIDLSDLGAFMAVARARGFRDAARVSGASPSALSDAVRRVEAQLGVRLLHRTTRSVAPTEAGARLMERLGPALGEVEAA
LDVVNGFRDRPAGTLRLNVPVSAARLVLPSLVPDFLAAYPDIRLEITAEDTFVDLLAAGCDAGIRYDERLEQDMIAVPIG
PRTQRFATAAAPAYLDRRGRPAHPRDLLAHACLLARFSSGAMMAWEFERDGEVVRVEPTGPLLVSVGAATELAVEAAVAG
TGIIALFEDWLRPHLDSGALEPVLEAWWPRFSGPFLYYPGRRLVPAPLRAFVDFVRTRQEG
>Mature_300_residues
SIDLSDLGAFMAVARARGFRDAARVSGASPSALSDAVRRVEAQLGVRLLHRTTRSVAPTEAGARLMERLGPALGEVEAAL
DVVNGFRDRPAGTLRLNVPVSAARLVLPSLVPDFLAAYPDIRLEITAEDTFVDLLAAGCDAGIRYDERLEQDMIAVPIGP
RTQRFATAAAPAYLDRRGRPAHPRDLLAHACLLARFSSGAMMAWEFERDGEVVRVEPTGPLLVSVGAATELAVEAAVAGT
GIIALFEDWLRPHLDSGALEPVLEAWWPRFSGPFLYYPGRRLVPAPLRAFVDFVRTRQEG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=41.8060200668896, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=36.7003367003367, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=31.7567567567568, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=29.0102389078498, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=26.9230769230769, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693193, Length=286, Percent_Identity=29.7202797202797, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789639, Length=271, Percent_Identity=28.7822878228782, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788706, Length=146, Percent_Identity=32.8767123287671, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786448, Length=178, Percent_Identity=30.3370786516854, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790399, Length=141, Percent_Identity=29.7872340425532, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32575; Mature: 32444

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDLSDLGAFMAVARARGFRDAARVSGASPSALSDAVRRVEAQLGVRLLHRTTRSVAPT
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EAGARLMERLGPALGEVEAALDVVNGFRDRPAGTLRLNVPVSAARLVLPSLVPDFLAAYP
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
DIRLEITAEDTFVDLLAAGCDAGIRYDERLEQDMIAVPIGPRTQRFATAAAPAYLDRRGR
CCEEEEECCHHHHHHHHHCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
PAHPRDLLAHACLLARFSSGAMMAWEFERDGEVVRVEPTGPLLVSVGAATELAVEAAVAG
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCEEEEECCHHHHHHHHHHHC
TGIIALFEDWLRPHLDSGALEPVLEAWWPRFSGPFLYYPGRRLVPAPLRAFVDFVRTRQE
CHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCC
G
C
>Mature Secondary Structure 
SIDLSDLGAFMAVARARGFRDAARVSGASPSALSDAVRRVEAQLGVRLLHRTTRSVAPT
CCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EAGARLMERLGPALGEVEAALDVVNGFRDRPAGTLRLNVPVSAARLVLPSLVPDFLAAYP
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
DIRLEITAEDTFVDLLAAGCDAGIRYDERLEQDMIAVPIGPRTQRFATAAAPAYLDRRGR
CCEEEEECCHHHHHHHHHCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
PAHPRDLLAHACLLARFSSGAMMAWEFERDGEVVRVEPTGPLLVSVGAATELAVEAAVAG
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCEEEEECCHHHHHHHHHHHC
TGIIALFEDWLRPHLDSGALEPVLEAWWPRFSGPFLYYPGRRLVPAPLRAFVDFVRTRQE
CHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]