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The map label for this gene is copA [H]

Identifier: 158423228

GI number: 158423228

Start: 1829874

End: 1831133

Strand: Reverse

Name: copA [H]

Synonym: AZC_1604

Alternate gene names: 158423228

Gene position: 1831133-1829874 (Counterclockwise)

Preceding gene: 158423229

Following gene: 158423226

Centisome position: 34.1

GC content: 72.38

Gene sequence:

>1260_bases
TTGCGCGTCCCAGCCTTCTCCCGCCGCGCGGCCCTTTCCGGCGCCGCCGCCTTGACCCTGAGCGGCCTGCTGCCGCGCCT
GGCCTTCGCACAGTCGGCCGCAGCGCCGGTCTCGCTGAAGGCAGCCACCGCCGACCGCATCGAACTCGCGGGTGCCGGGC
CCATCGACCTCTTCGAGGGCGGGCTCCCCGGTCCGTTTTTGCGGGTGAAGAAGGGAGAGACGCTTTCGGTTGCCGCCGCC
AACGCGCTCAAGGCGCCCATGGACGTAACCTGGCACGGCGTGCGCGTCCCCAACGCGCTTGATGGCGTGCCCGGCCTCAC
CGGCCCGGCCATCGCGCCCGGCGCCAGCCGCACCGTCAGCTTCGCGCCGCCGGATGCCGGCACCTTCTGGTATCACGCGT
TCGACGCCGCACAGACCCGCCGGGCGCTCGCCGGCGCGCTGATCGTGGAGGAGCCCGGCCCCTCCCCCTTCGGCGCCGAC
CACACGCTGCTCATCCAGACCTGGGCGCCGGACCCGGTGCTCGGCATGCCGCTCATCACCGTGAATGGCGCGGTCTCGCC
CACCCTTCAGGCCCCCTCCGCCGCCCGCGCGCGGCTGCGTCTCATCAATGCCTCGGTGGACTTCCTCAAGCTCCATGTGG
TGGACGCCCAAAGCTGGGTCATGGCCATCGACGGCCAGCCGACCTCCCCCTTCGTACTGAAGGACGGGCGGGCGCAACTG
GTGCCGGGCGGGCGCATCGACCTCGCGCTGGACGTCAACCTGAGTGGCGGCGCGGGCGACCCCATCATCCTCGAGATCGA
GACGCCGAAAGCGCCTGTGCAACTGGCGCTGATCGCGCCCGTGGGCGCCAGCACCGCGCCGGCCCCAACGGCGACACCCG
CCGCCCTGCCCGCCAATGCCCTGCCGACCGAGATCCCGCTTCAGGGCGCGACACGGGCGGAACTGGCCCTCGGCCCCGGC
GCGGCGAACCTCGCCAACCTGCCGACCCTGTTCTCGGTCGCGGCGGGCAAGTCCGCCGTGGTGACGCTGGCGAACAAGCT
GGAGGAGCCGGTGGCCGTGCATTTCCACGGCATGCCGGTCCGCGTGCTGGACGGCGCGGACGACGGCTGGAAGCCCTGGT
GGCACGACACCGTGCCTGTGCCGGGCAAGGCCACCGTGCGCGTGGCCTTGCGGCCCGATGCTGCCGGCAAATGGGCCATC
CTCGGCCAGAAGGGCGGCTCGACGGAGATCGTCGCCGCCGCCGCTTATGAAGTGAAGTGA

Upstream 100 bases:

>100_bases
CCGCGGGACCACACAATGGTGCCACCAATCGCCACTTGCCCTTTGGGATGCGGCGAGGGAAGGTCGCGGCGCAGTTTCAA
AAAGTTGCGGAGCGATCGTC

Downstream 100 bases:

>100_bases
GGCGCGTTTCGGACCGCCATCCGATGCCCCGGAATTGACCGGGGCATCTCTCACCCGGCGCGCGCCCCCAAAGCCTCGAA
CAGCGCCGCATAAACTTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRVPAFSRRAALSGAAALTLSGLLPRLAFAQSAAAPVSLKAATADRIELAGAGPIDLFEGGLPGPFLRVKKGETLSVAAA
NALKAPMDVTWHGVRVPNALDGVPGLTGPAIAPGASRTVSFAPPDAGTFWYHAFDAAQTRRALAGALIVEEPGPSPFGAD
HTLLIQTWAPDPVLGMPLITVNGAVSPTLQAPSAARARLRLINASVDFLKLHVVDAQSWVMAIDGQPTSPFVLKDGRAQL
VPGGRIDLALDVNLSGGAGDPIILEIETPKAPVQLALIAPVGASTAPAPTATPAALPANALPTEIPLQGATRAELALGPG
AANLANLPTLFSVAAGKSAVVTLANKLEEPVAVHFHGMPVRVLDGADDGWKPWWHDTVPVPGKATVRVALRPDAAGKWAI
LGQKGGSTEIVAAAAYEVK

Sequences:

>Translated_419_residues
MRVPAFSRRAALSGAAALTLSGLLPRLAFAQSAAAPVSLKAATADRIELAGAGPIDLFEGGLPGPFLRVKKGETLSVAAA
NALKAPMDVTWHGVRVPNALDGVPGLTGPAIAPGASRTVSFAPPDAGTFWYHAFDAAQTRRALAGALIVEEPGPSPFGAD
HTLLIQTWAPDPVLGMPLITVNGAVSPTLQAPSAARARLRLINASVDFLKLHVVDAQSWVMAIDGQPTSPFVLKDGRAQL
VPGGRIDLALDVNLSGGAGDPIILEIETPKAPVQLALIAPVGASTAPAPTATPAALPANALPTEIPLQGATRAELALGPG
AANLANLPTLFSVAAGKSAVVTLANKLEEPVAVHFHGMPVRVLDGADDGWKPWWHDTVPVPGKATVRVALRPDAAGKWAI
LGQKGGSTEIVAAAAYEVK
>Mature_419_residues
MRVPAFSRRAALSGAAALTLSGLLPRLAFAQSAAAPVSLKAATADRIELAGAGPIDLFEGGLPGPFLRVKKGETLSVAAA
NALKAPMDVTWHGVRVPNALDGVPGLTGPAIAPGASRTVSFAPPDAGTFWYHAFDAAQTRRALAGALIVEEPGPSPFGAD
HTLLIQTWAPDPVLGMPLITVNGAVSPTLQAPSAARARLRLINASVDFLKLHVVDAQSWVMAIDGQPTSPFVLKDGRAQL
VPGGRIDLALDVNLSGGAGDPIILEIETPKAPVQLALIAPVGASTAPAPTATPAALPANALPTEIPLQGATRAELALGPG
AANLANLPTLFSVAAGKSAVVTLANKLEEPVAVHFHGMPVRVLDGADDGWKPWWHDTVPVPGKATVRVALRPDAAGKWAI
LGQKGGSTEIVAAAAYEVK

Specific function: Mediates copper resistance by sequestration of copper in the periplasm along with the copper-binding protein CopC. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=368, Percent_Identity=26.3586956521739, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 42795; Mature: 42795

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPAFSRRAALSGAAALTLSGLLPRLAFAQSAAAPVSLKAATADRIELAGAGPIDLFEG
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCHHHHCC
GLPGPFLRVKKGETLSVAAANALKAPMDVTWHGVRVPNALDGVPGLTGPAIAPGASRTVS
CCCCCEEEEECCCEEEEEEHHHHCCCCCEEEEEEECCCHHCCCCCCCCCCCCCCCCCEEE
FAPPDAGTFWYHAFDAAQTRRALAGALIVEEPGPSPFGADHTLLIQTWAPDPVLGMPLIT
ECCCCCCCEEEEEHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEE
VNGAVSPTLQAPSAARARLRLINASVDFLKLHVVDAQSWVMAIDGQPTSPFVLKDGRAQL
ECCCCCCCCCCCCHHCEEEEEEECCEEEEEEEEEECCCEEEEECCCCCCCEEEECCCEEE
VPGGRIDLALDVNLSGGAGDPIILEIETPKAPVQLALIAPVGASTAPAPTATPAALPANA
CCCCEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
LPTEIPLQGATRAELALGPGAANLANLPTLFSVAAGKSAVVTLANKLEEPVAVHFHGMPV
CCCCCCCCCCCCEEEEECCCCCCHHCCCHHEEHHCCCCEEEEEHHHCCCCEEEEECCCCE
RVLDGADDGWKPWWHDTVPVPGKATVRVALRPDAAGKWAILGQKGGSTEIVAAAAYEVK
EEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MRVPAFSRRAALSGAAALTLSGLLPRLAFAQSAAAPVSLKAATADRIELAGAGPIDLFEG
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCHHHHCC
GLPGPFLRVKKGETLSVAAANALKAPMDVTWHGVRVPNALDGVPGLTGPAIAPGASRTVS
CCCCCEEEEECCCEEEEEEHHHHCCCCCEEEEEEECCCHHCCCCCCCCCCCCCCCCCEEE
FAPPDAGTFWYHAFDAAQTRRALAGALIVEEPGPSPFGADHTLLIQTWAPDPVLGMPLIT
ECCCCCCCEEEEEHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEE
VNGAVSPTLQAPSAARARLRLINASVDFLKLHVVDAQSWVMAIDGQPTSPFVLKDGRAQL
ECCCCCCCCCCCCHHCEEEEEEECCEEEEEEEEEECCCEEEEECCCCCCCEEEECCCEEE
VPGGRIDLALDVNLSGGAGDPIILEIETPKAPVQLALIAPVGASTAPAPTATPAALPANA
CCCCEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
LPTEIPLQGATRAELALGPGAANLANLPTLFSVAAGKSAVVTLANKLEEPVAVHFHGMPV
CCCCCCCCCCCCEEEEECCCCCCHHCCCHHEEHHCCCCEEEEEHHHCCCCEEEEECCCCE
RVLDGADDGWKPWWHDTVPVPGKATVRVALRPDAAGKWAILGQKGGSTEIVAAAAYEVK
EEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3372485; 1924351 [H]