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The map label for this gene is crt [H]

Identifier: 158423168

GI number: 158423168

Start: 1756144

End: 1757322

Strand: Direct

Name: crt [H]

Synonym: AZC_1544

Alternate gene names: 158423168

Gene position: 1756144-1757322 (Clockwise)

Preceding gene: 158423162

Following gene: 158423169

Centisome position: 32.7

GC content: 69.13

Gene sequence:

>1179_bases
GTGCGCGAGGGCTGCGATGCCGCGCCCTTGCGCTTCCGCCCGCTCGCGTTGACGCTGGCCTGCGCGGGGTCTAACCCTGC
ACCGTCCTTTCAGTGGCGAGGAGCCCCCGTGACCCCTGAGCCCGAGGTTCTGTTCGAGCGCCGCGGCGCGGCCGGCCTCA
TCACCCTCAATCGCCCCAAGGCCCTCAACGCTTTGACGCATGCCATGGTGCAGGCCATCGATCCGCGGTTGCGGGCGTGG
GCACGTGATCCTGGCGTGACGCGGGTGATCCTGAAGGCGGCGGGCGAGCGCGCCTTCTGCGCCGGCGGCGACGTTCGGCA
GATCTATGATCTCGGCCGCGCGGGGCGGCAGGCGGAGGCTCTCGCCTTCTGGCGCGAGGAATATGTTCTCAATCATTTGA
TCGGGACCTATCCCAAGCCCTTCGTCTCGCTCATCGACGGCATCTGCATGGGCGGCGGCTTCGGCCTCTCCGCCCACGGC
ACCTATCGGGTGGGCGGGGATCGCTATCTCTTCGCCATGCCGGAAGTGAACATCGGCCTCTTTCCGGATGTGGGCGGCAC
CTATGTGCTGCCGCGCCTGCCGAAGGCGGCTGGCGTCTATCTCGCTTTCACCGGCAACCGTATCAAGACCGCCGACGGCC
TGCACGTGGGTCTGCTGACCCATGCGGTGCCCTCCGCCGGCATGTCCGCCCTGGAAGAGGCGCTGTGCGCGGGCGGCGCG
GTGGCTGAGGTGCTCGCCGCCCATGCGGTGGACCCGGGTCCCGCGCCCATTCTCGCCCATGAAGCCTTCATCGCGGAGGC
CTTCGCTTCGGCCGACGTGTTCGCCGTCCTGGCAGCGCTCGATGCCGCCGCCGGGCGTGGCGGGCCGGAGGCGGATTTCG
CGCGCGAGACCGCGGCGGCCCTCCACACCAAATCGCCCACCAGCCTGGCGATTGCCGCCGAGCAGATGCGGCGCGGCCCG
GCTCTCAGCCTCGGCGAGGCCCTGAAAGCCGAATTCCGCGTCGTGACCCGCGTCGCCCATGGCCATGATTTCTACGAAGG
GGTGCGGGCGCTGCTGGTGGACAAGGACAATACGCCCCGCTGGCAGCCGCCGCGGCTCGCTGATGTGGATCCTGCCGCCA
TTGCGGCGCATTTCGATCCCATTGCCGAGGAACTGGAATTTCCGGCCGGAACCGCATGA

Upstream 100 bases:

>100_bases
CGGGGAAGGCTTCGGCCTCTTGCAGAAGCTCCGGGCGGGCGCACAAAAATGCCGCAACGGCAGGCATCGCGACCGGCTCT
TTATATCGTCTCGAAACAGC

Downstream 100 bases:

>100_bases
GCCATTACGACCCCATCGATGCCAGCGCCCGCGCGCGCATGGAACGCCTGACGCCCTGGCGTCGGCGCCTGGTCTTCTTC
CTGCGCGCGGTCGCCTTCTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MREGCDAAPLRFRPLALTLACAGSNPAPSFQWRGAPVTPEPEVLFERRGAAGLITLNRPKALNALTHAMVQAIDPRLRAW
ARDPGVTRVILKAAGERAFCAGGDVRQIYDLGRAGRQAEALAFWREEYVLNHLIGTYPKPFVSLIDGICMGGGFGLSAHG
TYRVGGDRYLFAMPEVNIGLFPDVGGTYVLPRLPKAAGVYLAFTGNRIKTADGLHVGLLTHAVPSAGMSALEEALCAGGA
VAEVLAAHAVDPGPAPILAHEAFIAEAFASADVFAVLAALDAAAGRGGPEADFARETAAALHTKSPTSLAIAAEQMRRGP
ALSLGEALKAEFRVVTRVAHGHDFYEGVRALLVDKDNTPRWQPPRLADVDPAAIAAHFDPIAEELEFPAGTA

Sequences:

>Translated_392_residues
MREGCDAAPLRFRPLALTLACAGSNPAPSFQWRGAPVTPEPEVLFERRGAAGLITLNRPKALNALTHAMVQAIDPRLRAW
ARDPGVTRVILKAAGERAFCAGGDVRQIYDLGRAGRQAEALAFWREEYVLNHLIGTYPKPFVSLIDGICMGGGFGLSAHG
TYRVGGDRYLFAMPEVNIGLFPDVGGTYVLPRLPKAAGVYLAFTGNRIKTADGLHVGLLTHAVPSAGMSALEEALCAGGA
VAEVLAAHAVDPGPAPILAHEAFIAEAFASADVFAVLAALDAAAGRGGPEADFARETAAALHTKSPTSLAIAAEQMRRGP
ALSLGEALKAEFRVVTRVAHGHDFYEGVRALLVDKDNTPRWQPPRLADVDPAAIAAHFDPIAEELEFPAGTA
>Mature_392_residues
MREGCDAAPLRFRPLALTLACAGSNPAPSFQWRGAPVTPEPEVLFERRGAAGLITLNRPKALNALTHAMVQAIDPRLRAW
ARDPGVTRVILKAAGERAFCAGGDVRQIYDLGRAGRQAEALAFWREEYVLNHLIGTYPKPFVSLIDGICMGGGFGLSAHG
TYRVGGDRYLFAMPEVNIGLFPDVGGTYVLPRLPKAAGVYLAFTGNRIKTADGLHVGLLTHAVPSAGMSALEEALCAGGA
VAEVLAAHAVDPGPAPILAHEAFIAEAFASADVFAVLAALDAAAGRGGPEADFARETAAALHTKSPTSLAIAAEQMRRGP
ALSLGEALKAEFRVVTRVAHGHDFYEGVRALLVDKDNTPRWQPPRLADVDPAAIAAHFDPIAEELEFPAGTA

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=357, Percent_Identity=43.1372549019608, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI37594469, Length=303, Percent_Identity=43.5643564356436, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI194097323, Length=201, Percent_Identity=32.8358208955224, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI31542718, Length=176, Percent_Identity=28.9772727272727, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787659, Length=187, Percent_Identity=26.7379679144385, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI221142681, Length=183, Percent_Identity=30.6010928961749, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788682, Length=178, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788597, Length=186, Percent_Identity=26.8817204301075, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=354, Percent_Identity=41.5254237288136, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI25144157, Length=354, Percent_Identity=41.5254237288136, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI25145438, Length=187, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=186, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=164, Percent_Identity=30.4878048780488, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=357, Percent_Identity=32.2128851540616, Blast_Score=179, Evalue=7e-46,
Organism=Drosophila melanogaster, GI28571729, Length=354, Percent_Identity=42.3728813559322, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI28571730, Length=354, Percent_Identity=42.3728813559322, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI20129971, Length=176, Percent_Identity=30.6818181818182, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24653477, Length=176, Percent_Identity=30.6818181818182, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24653139, Length=246, Percent_Identity=29.6747967479675, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920382, Length=242, Percent_Identity=28.099173553719, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 41316; Mature: 41316

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREGCDAAPLRFRPLALTLACAGSNPAPSFQWRGAPVTPEPEVLFERRGAAGLITLNRPK
CCCCCCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCHHHHHHCCCCCEEEEECCCH
ALNALTHAMVQAIDPRLRAWARDPGVTRVILKAAGERAFCAGGDVRQIYDLGRAGRQAEA
HHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCHHHH
LAFWREEYVLNHLIGTYPKPFVSLIDGICMGGGFGLSAHGTYRVGGDRYLFAMPEVNIGL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEECCCCCCEE
FPDVGGTYVLPRLPKAAGVYLAFTGNRIKTADGLHVGLLTHAVPSAGMSALEEALCAGGA
CCCCCCCEECCCCCCCCCEEEEEECCEEECCCCCEEHHHHHHCCHHHHHHHHHHHHCCHH
VAEVLAAHAVDPGPAPILAHEAFIAEAFASADVFAVLAALDAAAGRGGPEADFARETAAA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LHTKSPTSLAIAAEQMRRGPALSLGEALKAEFRVVTRVAHGHDFYEGVRALLVDKDNTPR
HHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEECCCCCC
WQPPRLADVDPAAIAAHFDPIAEELEFPAGTA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREGCDAAPLRFRPLALTLACAGSNPAPSFQWRGAPVTPEPEVLFERRGAAGLITLNRPK
CCCCCCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCHHHHHHCCCCCEEEEECCCH
ALNALTHAMVQAIDPRLRAWARDPGVTRVILKAAGERAFCAGGDVRQIYDLGRAGRQAEA
HHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCHHHH
LAFWREEYVLNHLIGTYPKPFVSLIDGICMGGGFGLSAHGTYRVGGDRYLFAMPEVNIGL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEECCCCCCEE
FPDVGGTYVLPRLPKAAGVYLAFTGNRIKTADGLHVGLLTHAVPSAGMSALEEALCAGGA
CCCCCCCEECCCCCCCCCEEEEEECCEEECCCCCEEHHHHHHCCHHHHHHHHHHHHCCHH
VAEVLAAHAVDPGPAPILAHEAFIAEAFASADVFAVLAALDAAAGRGGPEADFARETAAA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LHTKSPTSLAIAAEQMRRGPALSLGEALKAEFRVVTRVAHGHDFYEGVRALLVDKDNTPR
HHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEECCCCCC
WQPPRLADVDPAAIAAHFDPIAEELEFPAGTA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]