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The map label for this gene is hlyD [H]

Identifier: 158422988

GI number: 158422988

Start: 1540308

End: 1541450

Strand: Reverse

Name: hlyD [H]

Synonym: AZC_1364

Alternate gene names: 158422988

Gene position: 1541450-1540308 (Counterclockwise)

Preceding gene: 158422991

Following gene: 158422987

Centisome position: 28.71

GC content: 67.54

Gene sequence:

>1143_bases
TTGCTACCTATGGATGACATCATGGCCCGCACGAAGGGGATTCCCGCCGCCATCACCCTCATCTGGATCGCCAGCGGGCT
CGCCCTTGCAGCCCCACATCCTGCCCGCGCGGCTTCGGAACAGCCGGTGCCGGTCCAACTGGCGACGGCAGAGACCCGGG
ACGTTCCCGTCTTCGTCACCAGCCCGGGAACGGTCACTGCCTACAATTCCGTGACCGTTCGCACCCGGGTCGATGGAGAA
CTCCAACACATTCTCTTCAAGGAGGGGCAGGACGTGGCCGAAGGGCAGCTCCTCGCGCTCATCGACCCCCGCACCTACGA
GGCCGCGCTCCAATCCGCCAAGGCGCAACTCCAGCAGCATGAAGCGACCCTGTCGAACGCCCGGCTCAATCTCACGCGCG
ACACAGAGCTCGGCAAAAGCGACTTCGTGAGCGTCCAGACGCTCGATAACGAAAGGGCGAAGGTGGCCGAACTCGAGGCG
CAGGTGGCGTCGGATCAGGCCGCCATCTCCCGCGCCGCGACCGAGCTCTCCTACACGCGGATCGTCTCGCCGCTCTCCGG
CCGCGCCGGCCTGAGGCTGGTGGACCAGGGCAACATCGTCCACGCCGGCGACGCAGGGGGGCTCGTGGTCATCAATCAGA
TCGACCCCATCTCGGTCATTTCCACGCTGCCGGAGCAGAGCCTCCCGGCGGTGGTCAAGGCCATGCGCGCGGGTGCGCTT
CAGGCCCAGGCCCTCTCTCGCGAGGACGGGCGCATTCTGGCGACCGGCACGGTGTCGCTGATCGACAACCAGATCGACCC
GAACAGCGGCACGGTGAAGCTGAAGTCGGACTTCGCCAATGCGCGCGATGCCCTCTGGCCCGGCCAGTTCGTGGATATCA
AGGTGCGGGTGGATGTCCTGCCCCATGCAGTCACCATCCCCGCCTCGGCGCTTCAGCGCGGCCCACAAGGCCTGTTCGTC
TTCGCGGTCGGCCCCGACGACCGCGCGCAGACCGCACCGGTGAGTGCAGGGCAGATCGCCGACGGCACGGCAGTGATCGA
GACCGGCCTTGCGCCAGGCCAGCGCGTCATCACCGGCGGCCAGTACCGCGTGCGACCGGGCAGCCTCGTCACGGTCTCCG
TCAGCGGGGAGGCAGGCCAATGA

Upstream 100 bases:

>100_bases
GGCGCCCGCTTTCCGGCGAAGAGCCCGTTGCAGCCGGATCGGTCCGGCGCATCCGGTGCGAAGTGCCTCCTCGATCTGAA
CGCGGAACGACAGCTCGCCG

Downstream 100 bases:

>100_bases
GTGCGAGCAGCGAGAAGTGCGCCTCCTTGTCCGCCTGGTTCATCCGCCATCCGATCGGCACCTCCCTGCTCATGGCGGGC
CTTCTGGTGCTGGGCCTTGC

Product: secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLPMDDIMARTKGIPAAITLIWIASGLALAAPHPARAASEQPVPVQLATAETRDVPVFVTSPGTVTAYNSVTVRTRVDGE
LQHILFKEGQDVAEGQLLALIDPRTYEAALQSAKAQLQQHEATLSNARLNLTRDTELGKSDFVSVQTLDNERAKVAELEA
QVASDQAAISRAATELSYTRIVSPLSGRAGLRLVDQGNIVHAGDAGGLVVINQIDPISVISTLPEQSLPAVVKAMRAGAL
QAQALSREDGRILATGTVSLIDNQIDPNSGTVKLKSDFANARDALWPGQFVDIKVRVDVLPHAVTIPASALQRGPQGLFV
FAVGPDDRAQTAPVSAGQIADGTAVIETGLAPGQRVITGGQYRVRPGSLVTVSVSGEAGQ

Sequences:

>Translated_380_residues
MLPMDDIMARTKGIPAAITLIWIASGLALAAPHPARAASEQPVPVQLATAETRDVPVFVTSPGTVTAYNSVTVRTRVDGE
LQHILFKEGQDVAEGQLLALIDPRTYEAALQSAKAQLQQHEATLSNARLNLTRDTELGKSDFVSVQTLDNERAKVAELEA
QVASDQAAISRAATELSYTRIVSPLSGRAGLRLVDQGNIVHAGDAGGLVVINQIDPISVISTLPEQSLPAVVKAMRAGAL
QAQALSREDGRILATGTVSLIDNQIDPNSGTVKLKSDFANARDALWPGQFVDIKVRVDVLPHAVTIPASALQRGPQGLFV
FAVGPDDRAQTAPVSAGQIADGTAVIETGLAPGQRVITGGQYRVRPGSLVTVSVSGEAGQ
>Mature_380_residues
MLPMDDIMARTKGIPAAITLIWIASGLALAAPHPARAASEQPVPVQLATAETRDVPVFVTSPGTVTAYNSVTVRTRVDGE
LQHILFKEGQDVAEGQLLALIDPRTYEAALQSAKAQLQQHEATLSNARLNLTRDTELGKSDFVSVQTLDNERAKVAELEA
QVASDQAAISRAATELSYTRIVSPLSGRAGLRLVDQGNIVHAGDAGGLVVINQIDPISVISTLPEQSLPAVVKAMRAGAL
QAQALSREDGRILATGTVSLIDNQIDPNSGTVKLKSDFANARDALWPGQFVDIKVRVDVLPHAVTIPASALQRGPQGLFV
FAVGPDDRAQTAPVSAGQIADGTAVIETGLAPGQRVITGGQYRVRPGSLVTVSVSGEAGQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=330, Percent_Identity=43.3333333333333, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1786668, Length=370, Percent_Identity=30.5405405405405, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789665, Length=317, Percent_Identity=32.1766561514196, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789929, Length=358, Percent_Identity=30.7262569832402, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081796, Length=211, Percent_Identity=31.2796208530806, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39853; Mature: 39853

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPMDDIMARTKGIPAAITLIWIASGLALAAPHPARAASEQPVPVQLATAETRDVPVFVT
CCCHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEE
SPGTVTAYNSVTVRTRVDGELQHILFKEGQDVAEGQLLALIDPRTYEAALQSAKAQLQQH
CCCEEEEECEEEEEEECCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EATLSNARLNLTRDTELGKSDFVSVQTLDNERAKVAELEAQVASDQAAISRAATELSYTR
HHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVSPLSGRAGLRLVDQGNIVHAGDAGGLVVINQIDPISVISTLPEQSLPAVVKAMRAGAL
HHCCCCCCCCEEEEECCCEEEECCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCH
QAQALSREDGRILATGTVSLIDNQIDPNSGTVKLKSDFANARDALWPGQFVDIKVRVDVL
HHHHHCCCCCEEEEEEEEEEEECCCCCCCCEEEEECCCCCCHHCCCCCCEEEEEEEEEEC
PHAVTIPASALQRGPQGLFVFAVGPDDRAQTAPVSAGQIADGTAVIETGLAPGQRVITGG
CCEEECCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECC
QYRVRPGSLVTVSVSGEAGQ
EEEECCCCEEEEEECCCCCC
>Mature Secondary Structure
MLPMDDIMARTKGIPAAITLIWIASGLALAAPHPARAASEQPVPVQLATAETRDVPVFVT
CCCHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEE
SPGTVTAYNSVTVRTRVDGELQHILFKEGQDVAEGQLLALIDPRTYEAALQSAKAQLQQH
CCCEEEEECEEEEEEECCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EATLSNARLNLTRDTELGKSDFVSVQTLDNERAKVAELEAQVASDQAAISRAATELSYTR
HHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVSPLSGRAGLRLVDQGNIVHAGDAGGLVVINQIDPISVISTLPEQSLPAVVKAMRAGAL
HHCCCCCCCCEEEEECCCEEEECCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCH
QAQALSREDGRILATGTVSLIDNQIDPNSGTVKLKSDFANARDALWPGQFVDIKVRVDVL
HHHHHCCCCCEEEEEEEEEEEECCCCCCCCEEEEECCCCCCHHCCCCCCEEEEEEEEEEC
PHAVTIPASALQRGPQGLFVFAVGPDDRAQTAPVSAGQIADGTAVIETGLAPGQRVITGG
CCEEECCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECC
QYRVRPGSLVTVSVSGEAGQ
EEEECCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA