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The map label for this gene is yjcE [H]

Identifier: 158422971

GI number: 158422971

Start: 1516513

End: 1518141

Strand: Reverse

Name: yjcE [H]

Synonym: AZC_1347

Alternate gene names: 158422971

Gene position: 1518141-1516513 (Counterclockwise)

Preceding gene: 158422972

Following gene: 158422970

Centisome position: 28.27

GC content: 68.32

Gene sequence:

>1629_bases
ATGGCGACACTCAATCTCGTTCTCATCCTGGTCATCGCAGTGGTGATGAGCAGCTGGATCAGCCGGCTGCTGCCGCGCGT
GGCACCGCCCCTGGTGCAGATTGCCCTGGGTGCTGCCATGGGTCGCCTCGGGATCGATGCCGTCAGCATCAATCCGGACC
TGTTCTTCGTGCTCTTCCTGCCACCGCTGCTCTTCGTGGACGGTTGGCGGTTTTCCGGTCACGAGCTCATATCGCGAGCC
GGCCCGATCGCTTCGCTGGCCGTGGGGCTCGTGCTGGTGACCGTGCTCTGTGTCGGACCCGGCCTGCACGCGCTCATTCC
GCACATGCCGCTCGTCGCGACACTGGCGCTGGTGGCCGTGCTCTCCCCCACCGACGCCATCGCCGGAACGTCCCTGCTGA
AGCGGGCGCCGTTGTCCCGCCGTGCCGGCCGGATCATCGAAGGCGAGGCGCTCCTCAACGACGCCTCGGCGCTCATCTGT
CTGCATTATGTCGTCGTCCTTGGGTCGACGGCCACTCCCTCCGGCCCTTTCATCCTGGGAGAAATGATCTGGATCGGCGC
CGGCGGGCTGGCGATCGGCGCTGGCGTCGGCGTGATGATCCTGATGCTCAAGAATGCGATCCTGGCGCGCCTTGGAGAAA
CCACGGCAACGCAGATCCTCATCAGCCTGCTGTTCCCCTATGCGGCCTATCACGCAGCCGTCGCACTCGGCGCTTCCGGC
ATCCTCGCAGCCGTCGCGGCTGGCGTCGCCATGGGGCGGTGGGAACTGGGCGGCAACGCTCTCCCGGTCACGCGGCTCCG
CCGGGCGGCCATCTGGGAGACACTGGAATTCACGCTCAACGGGGTCATTTTCGTCCTTCTGGGAGAGCAATTGCCCGGCA
TCGTCGAAAAGGCACTCGCGAGCACCGCGCTCGGGGGGCACCTGCCCGTCCTTCGGCTGGGGCTCTATATCGCCGCGGCC
GCGACGGCGCTGACGCTGGTGCGTCTGCTGTGGGTGGGCGCCATGGTGGCCTGGCACGAGCGGCAGCAACGGGACGCGGT
CGGCACGAAAGTGCGCGTGCTGAAGGTCCTCGCGATGACATTCTCCGGCGTGCGCGGAGCGGTCACGCTCGCCGCCGCGC
TTGCTCTGCCCATGACACTGCCCGGCGGCCTCCCCTTCCCCGCGCGCGACCTTGTCATCGCCATTGCCGCTGGTGTTATC
CTGACCTCGCTCATCGTCGCAAACATCGCACTGCCCCTGCTCGCGGGGCAGCTAGCGGCGGCAGCCGAGGACGAGGACGC
CGAACAGCAAGCGGCACGGCTGCGCACGGCACAGGCCGCGATCGCCGCAGTGGAGCGGATGGCGCTCGAACAGGGCGACG
AAGCGAACGGCGAACCGCTGCTCTGGCAGGAGGCGTCCGCCGCGGTCCTGTCGTCCTATCGCCGGCAGGTGGAGCGGCTG
AGCGCATCGGACAGCGACCGGAGCGCCGCAGAGCTGCGCGGCACCGCCGAACGGCGTCTGCGGCTGGCCGGCCTTCACGC
ACAGCGGGCCGAGATCGCGGTGATGGTGGCCGAGCATCTCATCGACAATGAAGCCGCGCGCCGCCTGCTGCTGGAGCTGG
ATGGCCAGGAAGCCTGGCTGGCGAGCTGA

Upstream 100 bases:

>100_bases
GGCTTCACATGGCCAACCTCCATGGATCTCCGGCGTCCATTTCTGACAGCTCACGTTAGGGCAGCGGTGCACGTCCGGCC
ATCAGGCACACGGCACAATC

Downstream 100 bases:

>100_bases
ACGCAGGCGCCATTGCCTTCGGAGGAAGCGGCACGGCGGACACTGATCTCACCCCTTACCTTGTGTAATGCAAATGCATT
TCGCGGGCCGCAAGGTCCGT

Product: Na+/H+ antiporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MATLNLVLILVIAVVMSSWISRLLPRVAPPLVQIALGAAMGRLGIDAVSINPDLFFVLFLPPLLFVDGWRFSGHELISRA
GPIASLAVGLVLVTVLCVGPGLHALIPHMPLVATLALVAVLSPTDAIAGTSLLKRAPLSRRAGRIIEGEALLNDASALIC
LHYVVVLGSTATPSGPFILGEMIWIGAGGLAIGAGVGVMILMLKNAILARLGETTATQILISLLFPYAAYHAAVALGASG
ILAAVAAGVAMGRWELGGNALPVTRLRRAAIWETLEFTLNGVIFVLLGEQLPGIVEKALASTALGGHLPVLRLGLYIAAA
ATALTLVRLLWVGAMVAWHERQQRDAVGTKVRVLKVLAMTFSGVRGAVTLAAALALPMTLPGGLPFPARDLVIAIAAGVI
LTSLIVANIALPLLAGQLAAAAEDEDAEQQAARLRTAQAAIAAVERMALEQGDEANGEPLLWQEASAAVLSSYRRQVERL
SASDSDRSAAELRGTAERRLRLAGLHAQRAEIAVMVAEHLIDNEAARRLLLELDGQEAWLAS

Sequences:

>Translated_542_residues
MATLNLVLILVIAVVMSSWISRLLPRVAPPLVQIALGAAMGRLGIDAVSINPDLFFVLFLPPLLFVDGWRFSGHELISRA
GPIASLAVGLVLVTVLCVGPGLHALIPHMPLVATLALVAVLSPTDAIAGTSLLKRAPLSRRAGRIIEGEALLNDASALIC
LHYVVVLGSTATPSGPFILGEMIWIGAGGLAIGAGVGVMILMLKNAILARLGETTATQILISLLFPYAAYHAAVALGASG
ILAAVAAGVAMGRWELGGNALPVTRLRRAAIWETLEFTLNGVIFVLLGEQLPGIVEKALASTALGGHLPVLRLGLYIAAA
ATALTLVRLLWVGAMVAWHERQQRDAVGTKVRVLKVLAMTFSGVRGAVTLAAALALPMTLPGGLPFPARDLVIAIAAGVI
LTSLIVANIALPLLAGQLAAAAEDEDAEQQAARLRTAQAAIAAVERMALEQGDEANGEPLLWQEASAAVLSSYRRQVERL
SASDSDRSAAELRGTAERRLRLAGLHAQRAEIAVMVAEHLIDNEAARRLLLELDGQEAWLAS
>Mature_541_residues
ATLNLVLILVIAVVMSSWISRLLPRVAPPLVQIALGAAMGRLGIDAVSINPDLFFVLFLPPLLFVDGWRFSGHELISRAG
PIASLAVGLVLVTVLCVGPGLHALIPHMPLVATLALVAVLSPTDAIAGTSLLKRAPLSRRAGRIIEGEALLNDASALICL
HYVVVLGSTATPSGPFILGEMIWIGAGGLAIGAGVGVMILMLKNAILARLGETTATQILISLLFPYAAYHAAVALGASGI
LAAVAAGVAMGRWELGGNALPVTRLRRAAIWETLEFTLNGVIFVLLGEQLPGIVEKALASTALGGHLPVLRLGLYIAAAA
TALTLVRLLWVGAMVAWHERQQRDAVGTKVRVLKVLAMTFSGVRGAVTLAAALALPMTLPGGLPFPARDLVIAIAAGVIL
TSLIVANIALPLLAGQLAAAAEDEDAEQQAARLRTAQAAIAAVERMALEQGDEANGEPLLWQEASAAVLSSYRRQVERLS
ASDSDRSAAELRGTAERRLRLAGLHAQRAEIAVMVAEHLIDNEAARRLLLELDGQEAWLAS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=387, Percent_Identity=20.1550387596899, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI41872703, Length=480, Percent_Identity=23.125, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI110227626, Length=475, Percent_Identity=21.8947368421053, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI5454070, Length=475, Percent_Identity=21.8947368421053, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI294997330, Length=344, Percent_Identity=21.8023255813953, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI14211919, Length=352, Percent_Identity=22.7272727272727, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1790501, Length=554, Percent_Identity=37.5451263537906, Blast_Score=277, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71993590, Length=412, Percent_Identity=23.3009708737864, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71993582, Length=412, Percent_Identity=23.3009708737864, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25150332, Length=413, Percent_Identity=23.2445520581114, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71980847, Length=420, Percent_Identity=21.4285714285714, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221473215, Length=434, Percent_Identity=20.7373271889401, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364513, Length=426, Percent_Identity=21.1267605633803, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221473222, Length=426, Percent_Identity=21.1267605633803, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221473212, Length=256, Percent_Identity=22.65625, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281360447, Length=439, Percent_Identity=21.4123006833713, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 56644; Mature: 56513

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLNLVLILVIAVVMSSWISRLLPRVAPPLVQIALGAAMGRLGIDAVSINPDLFFVLFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHH
PPLLFVDGWRFSGHELISRAGPIASLAVGLVLVTVLCVGPGLHALIPHMPLVATLALVAV
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHH
LSPTDAIAGTSLLKRAPLSRRAGRIIEGEALLNDASALICLHYVVVLGSTATPSGPFILG
HCCCHHHHHHHHHHHCCCHHHCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEH
EMIWIGAGGLAIGAGVGVMILMLKNAILARLGETTATQILISLLFPYAAYHAAVALGASG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
ILAAVAAGVAMGRWELGGNALPVTRLRRAAIWETLEFTLNGVIFVLLGEQLPGIVEKALA
HHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
STALGGHLPVLRLGLYIAAAATALTLVRLLWVGAMVAWHERQQRDAVGTKVRVLKVLAMT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGVRGAVTLAAALALPMTLPGGLPFPARDLVIAIAAGVILTSLIVANIALPLLAGQLAA
HCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEDEDAEQQAARLRTAQAAIAAVERMALEQGDEANGEPLLWQEASAAVLSSYRRQVERL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
SASDSDRSAAELRGTAERRLRLAGLHAQRAEIAVMVAEHLIDNEAARRLLLELDGQEAWL
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHCC
AS
CC
>Mature Secondary Structure 
ATLNLVLILVIAVVMSSWISRLLPRVAPPLVQIALGAAMGRLGIDAVSINPDLFFVLFL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHH
PPLLFVDGWRFSGHELISRAGPIASLAVGLVLVTVLCVGPGLHALIPHMPLVATLALVAV
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHH
LSPTDAIAGTSLLKRAPLSRRAGRIIEGEALLNDASALICLHYVVVLGSTATPSGPFILG
HCCCHHHHHHHHHHHCCCHHHCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEH
EMIWIGAGGLAIGAGVGVMILMLKNAILARLGETTATQILISLLFPYAAYHAAVALGASG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
ILAAVAAGVAMGRWELGGNALPVTRLRRAAIWETLEFTLNGVIFVLLGEQLPGIVEKALA
HHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
STALGGHLPVLRLGLYIAAAATALTLVRLLWVGAMVAWHERQQRDAVGTKVRVLKVLAMT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGVRGAVTLAAALALPMTLPGGLPFPARDLVIAIAAGVILTSLIVANIALPLLAGQLAA
HCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEDEDAEQQAARLRTAQAAIAAVERMALEQGDEANGEPLLWQEASAAVLSSYRRQVERL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
SASDSDRSAAELRGTAERRLRLAGLHAQRAEIAVMVAEHLIDNEAARRLLLELDGQEAWL
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHCC
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]