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The map label for this gene is lytT [H]

Identifier: 158422923

GI number: 158422923

Start: 1447320

End: 1448006

Strand: Reverse

Name: lytT [H]

Synonym: AZC_1299

Alternate gene names: 158422923

Gene position: 1448006-1447320 (Counterclockwise)

Preceding gene: 158422924

Following gene: 158422922

Centisome position: 26.97

GC content: 70.31

Gene sequence:

>687_bases
ATGCGTCGGCTGTTGGCCGCCCACGGCGACGTGGCCATTCTCGGTGAAGCCGACAACCTGTCCGGGGCGGTTCAGCTCAT
TTCGGCGGAAAAGCCGGATGCGGTGTTCCTCGACATCGACCTCGGAAGCAGCGACGGCTTCCAGTTGATCGCTCGGCTCG
ATCAGGCGCCGCATGTGGTGTTCGTCACCGCCCATGCGCAATATGCGGTGGATGCGTTCGCCGCCGCAGCGGTCGACTAT
CTGCTGAAGCCGGTGATACCCGAGCGCCTGGCGGAGGCCATCGCGCGCCTGCGCCGCAACCGCCCGCCCCCGGCAGCCGG
CGGCGAGAGCGGGGGCGCGCACGACATCCTGGAGCTGCGCACCCCCAACCGCACGGTTCTCGCCAGCCCCGCCGAGATCG
CCGCTTTGTGCGCGGAGGGCGATTTCACCCGCGTGGTGCTGGCGGACCAGCCCTCCTTGCTGATCTGGCGCACCCTCAGC
CACTTCGAGAGCGTGCTGCCCGCCCCGCCCTTCGTGCGCCTCAGCCGCTCGCTGATCCTCAACCGCGACCGCCTGCGCAG
CTTCGAGACCCCTTCTCGCAACCGCTCGCGGGTGACGCTGGACGGTGTCGGCGAGCCTCTGGTGCTGGGCCGCGCGGCCA
CCAGCCGCCTGCGCGACGTGGTCTCCGGCGGCACGGAGCGGCTTTAG

Upstream 100 bases:

>100_bases
ATTGCACCCATGGCGACGTGGTCGTGGCCGAACTTCTGCTGGAGGGCGAGCCGTGCTCCGGGTCGTGATCGTCGATGACG
AGCCCCTGGCCATCCGCGCC

Downstream 100 bases:

>100_bases
GCGGAGGAACGGACGGGACGCCAGAGGCTGCCTGTGGTTGGTGATCCGAAATGAATGCGTGAATTTCCGCTTCAGAGTTC
GGGACAGGCCCTGCGCTGGT

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRRLLAAHGDVAILGEADNLSGAVQLISAEKPDAVFLDIDLGSSDGFQLIARLDQAPHVVFVTAHAQYAVDAFAAAAVDY
LLKPVIPERLAEAIARLRRNRPPPAAGGESGGAHDILELRTPNRTVLASPAEIAALCAEGDFTRVVLADQPSLLIWRTLS
HFESVLPAPPFVRLSRSLILNRDRLRSFETPSRNRSRVTLDGVGEPLVLGRAATSRLRDVVSGGTERL

Sequences:

>Translated_228_residues
MRRLLAAHGDVAILGEADNLSGAVQLISAEKPDAVFLDIDLGSSDGFQLIARLDQAPHVVFVTAHAQYAVDAFAAAAVDY
LLKPVIPERLAEAIARLRRNRPPPAAGGESGGAHDILELRTPNRTVLASPAEIAALCAEGDFTRVVLADQPSLLIWRTLS
HFESVLPAPPFVRLSRSLILNRDRLRSFETPSRNRSRVTLDGVGEPLVLGRAATSRLRDVVSGGTERL
>Mature_228_residues
MRRLLAAHGDVAILGEADNLSGAVQLISAEKPDAVFLDIDLGSSDGFQLIARLDQAPHVVFVTAHAQYAVDAFAAAAVDY
LLKPVIPERLAEAIARLRRNRPPPAAGGESGGAHDILELRTPNRTVLASPAEIAALCAEGDFTRVVLADQPSLLIWRTLS
HFESVLPAPPFVRLSRSLILNRDRLRSFETPSRNRSRVTLDGVGEPLVLGRAATSRLRDVVSGGTERL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=227, Percent_Identity=26.431718061674, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082052, Length=103, Percent_Identity=37.8640776699029, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24533; Mature: 24533

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLAAHGDVAILGEADNLSGAVQLISAEKPDAVFLDIDLGSSDGFQLIARLDQAPHVV
CCCCEECCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCEE
FVTAHAQYAVDAFAAAAVDYLLKPVIPERLAEAIARLRRNRPPPAAGGESGGAHDILELR
EEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
TPNRTVLASPAEIAALCAEGDFTRVVLADQPSLLIWRTLSHFESVLPAPPFVRLSRSLIL
CCCCEEEECHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHH
NRDRLRSFETPSRNRSRVTLDGVGEPLVLGRAATSRLRDVVSGGTERL
CHHHHHCCCCCCCCCCEEEECCCCCCEEECHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRLLAAHGDVAILGEADNLSGAVQLISAEKPDAVFLDIDLGSSDGFQLIARLDQAPHVV
CCCCEECCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCEE
FVTAHAQYAVDAFAAAAVDYLLKPVIPERLAEAIARLRRNRPPPAAGGESGGAHDILELR
EEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
TPNRTVLASPAEIAALCAEGDFTRVVLADQPSLLIWRTLSHFESVLPAPPFVRLSRSLIL
CCCCEEEECHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHH
NRDRLRSFETPSRNRSRVTLDGVGEPLVLGRAATSRLRDVVSGGTERL
CHHHHHCCCCCCCCCCEEEECCCCCCEEECHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]