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The map label for this gene is corA [H]

Identifier: 158422819

GI number: 158422819

Start: 1337905

End: 1338885

Strand: Direct

Name: corA [H]

Synonym: AZC_1195

Alternate gene names: 158422819

Gene position: 1337905-1338885 (Clockwise)

Preceding gene: 158422817

Following gene: 158422822

Centisome position: 24.92

GC content: 66.36

Gene sequence:

>981_bases
ATGCTGATTGCCTATGTCCCCCGCGCGGGTGCGCTGGTGTCGGAGGTCGTTGCCGCCGACGCCAACATCCCGGCCGGGGC
GGTCTGGCTCGATCTGATCGCGCCGGAAGCGTTCGAGGACCGCACCATCGAGCGCGCCCTCGGCATCGAGATTCCCACGC
GCGAAGAGATGCGGGAGATCGAGGCCTCCTCCCGCCTCTATGCGGAGCGGGGCGCCCGCTACATGACGCTGTCGGTGCTC
TGCGGCGCGCAGACCGACACGCCCGAGGTCACGCCCGTGACCTTCATCCTGACCGACGCCGTCCTCGTGACGGTGCGCTA
CAGCGAACCGAAGGCCTTTCCCTTGCTGGCCGATCGGCTGCGCCGCGCCTGCCCCGATCCGCTCTCGGCGGAGACGCTTC
TCGCCGAACTGCTCGACACGATCATCGACCGCGTGGCCGACGTGCTGGAGATGTGCGGCGACGGCATCGACCGCCTGTCC
CGGCGCACCTTCGAGCCGCAGGCCAAGGGCAGCGACGCCAACCAGATCTATCGCGCGATCCTCACCCAGCTTGGCCGCAA
GGAGCGCCTCACCTCCTACGCGCGGGAAAGCCTGTCCTCGCTCACCCGCCTGCTCGCCTTCCTCGGCGCCGATATCGTGG
AAGGGCACACGCTGAGCCCCAAGGGCCGCGATGCGGTGAAGAGCATGATGCGCGATGTGACGGGCCTGTCCGACTATGCG
GTCTTCCTCGTCACCAAGCTGCAGTTCCTGCTCGACGCCACCATCGGCATGGTGAGCCTCGAACAGAACAACATCATCAA
GATCTTTGCCGTGCTCTCGGTGGTGCTGATGCCGCCCACCCTGATCGCCTCGATCTACGGCATGAATTTCCAGCACATGC
CCGAACTGGCCGAGACCTACGGCTATCCCCTGGCGCTCTGCGCCATGGTGGTGTCGGGCATCCTGCCCTACCTCTTCTTC
AAATGGCGGCGCTGGCTCTGA

Upstream 100 bases:

>100_bases
GTGGCGGCCGCGCTCTTGAAGAGGCGGCGCCGGGTTCGGCCTGATGGCAGGTGGTTGCTGAGCGCCCGAGGCGTGGCGCG
CGGACTGGAGCCGAGCGCCC

Downstream 100 bases:

>100_bases
GCCTTCGGCGGCTCAGACGTGCTGACCGCCGTTGATGAGGATTTCCGCGCCATTGAGATAGGACGAGGTCTCCGTGCACA
GCACGTAGATGATCTTCGCC

Product: magnesium/cobalt transporter

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLIAYVPRAGALVSEVVAADANIPAGAVWLDLIAPEAFEDRTIERALGIEIPTREEMREIEASSRLYAERGARYMTLSVL
CGAQTDTPEVTPVTFILTDAVLVTVRYSEPKAFPLLADRLRRACPDPLSAETLLAELLDTIIDRVADVLEMCGDGIDRLS
RRTFEPQAKGSDANQIYRAILTQLGRKERLTSYARESLSSLTRLLAFLGADIVEGHTLSPKGRDAVKSMMRDVTGLSDYA
VFLVTKLQFLLDATIGMVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFQHMPELAETYGYPLALCAMVVSGILPYLFF
KWRRWL

Sequences:

>Translated_326_residues
MLIAYVPRAGALVSEVVAADANIPAGAVWLDLIAPEAFEDRTIERALGIEIPTREEMREIEASSRLYAERGARYMTLSVL
CGAQTDTPEVTPVTFILTDAVLVTVRYSEPKAFPLLADRLRRACPDPLSAETLLAELLDTIIDRVADVLEMCGDGIDRLS
RRTFEPQAKGSDANQIYRAILTQLGRKERLTSYARESLSSLTRLLAFLGADIVEGHTLSPKGRDAVKSMMRDVTGLSDYA
VFLVTKLQFLLDATIGMVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFQHMPELAETYGYPLALCAMVVSGILPYLFF
KWRRWL
>Mature_326_residues
MLIAYVPRAGALVSEVVAADANIPAGAVWLDLIAPEAFEDRTIERALGIEIPTREEMREIEASSRLYAERGARYMTLSVL
CGAQTDTPEVTPVTFILTDAVLVTVRYSEPKAFPLLADRLRRACPDPLSAETLLAELLDTIIDRVADVLEMCGDGIDRLS
RRTFEPQAKGSDANQIYRAILTQLGRKERLTSYARESLSSLTRLLAFLGADIVEGHTLSPKGRDAVKSMMRDVTGLSDYA
VFLVTKLQFLLDATIGMVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFQHMPELAETYGYPLALCAMVVSGILPYLFF
KWRRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=301, Percent_Identity=34.8837209302326, Blast_Score=171, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36123; Mature: 36123

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAYVPRAGALVSEVVAADANIPAGAVWLDLIAPEAFEDRTIERALGIEIPTREEMREI
CEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH
EASSRLYAERGARYMTLSVLCGAQTDTPEVTPVTFILTDAVLVTVRYSEPKAFPLLADRL
HHHHHHHHHHCCCEEEEHEEECCCCCCCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHH
RRACPDPLSAETLLAELLDTIIDRVADVLEMCGDGIDRLSRRTFEPQAKGSDANQIYRAI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHH
LTQLGRKERLTSYARESLSSLTRLLAFLGADIVEGHTLSPKGRDAVKSMMRDVTGLSDYA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHH
VFLVTKLQFLLDATIGMVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFQHMPELAETY
HHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHC
GYPLALCAMVVSGILPYLFFKWRRWL
CCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIAYVPRAGALVSEVVAADANIPAGAVWLDLIAPEAFEDRTIERALGIEIPTREEMREI
CEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH
EASSRLYAERGARYMTLSVLCGAQTDTPEVTPVTFILTDAVLVTVRYSEPKAFPLLADRL
HHHHHHHHHHCCCEEEEHEEECCCCCCCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHH
RRACPDPLSAETLLAELLDTIIDRVADVLEMCGDGIDRLSRRTFEPQAKGSDANQIYRAI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHH
LTQLGRKERLTSYARESLSSLTRLLAFLGADIVEGHTLSPKGRDAVKSMMRDVTGLSDYA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHH
VFLVTKLQFLLDATIGMVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFQHMPELAETY
HHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHC
GYPLALCAMVVSGILPYLFFKWRRWL
CCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]