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The map label for this gene is etfA [H]

Identifier: 158422802

GI number: 158422802

Start: 1316963

End: 1318153

Strand: Direct

Name: etfA [H]

Synonym: AZC_1178

Alternate gene names: 158422802

Gene position: 1316963-1318153 (Clockwise)

Preceding gene: 158422801

Following gene: 158422803

Centisome position: 24.53

GC content: 75.82

Gene sequence:

>1191_bases
GTGAGCCGTCTCCGCCGCGATCCCCGCGCCGAGCGCGCGGCCCGGGCCCTGCCCACGCAAGGCCGGCCGCGTCTCCAGCT
TGGCACGCCCGTGTCGGAGGGGCGGCTGCGGCGCAATCCCTTCGCCGAACGCGCGGCTGCGGAGGTGCAGGGCCGGACCC
GCCTGCGGCTCGACCGCGCCGGCGGTGGCCCCCGTTCGGTCTCTGTCGCCTCCCCGCCGGCAGCGCCCGAACCGAGGGCG
CCTGAACGGCGGCTGGTGCCGGAGCCGGCCTTTCTCGTCCTTGCCGTCGCCGATGTGCCGGGCGGGCACCTCTCCGTCCA
TGACCGGCAGGTGCTGGGCGCCGCCCGTGTGCTGGCCGATGCCGGCGGCGGCGCCGTGGTGCTGCTCGGCGGAACGCTCC
CGCAGGATGCGGGCGCGGCCGGTGCCGACCGCATCGCGTGTCTGCCCGAAGCGGACGATCCGGACCGGCGCGCAGGTGCG
CTCATGGCCGCCATCGCCGCGCTGCGGCCGCGGCACGTGCTGTGGCCGGAAAGCCGGATCGGCGGCGATCTCGCCCGCCG
CGTGGCGGTGCGGATAGGCGAGGGCCTGTTCTGCGGCGCCGAGCAGGTGAGCGCCCGCGCCGTCGCCCGTCCCGCACGGG
GCCGCCGGGTGGAGCAGCGCCGTGAACCGCCCCTGCTGCTAACGCTCGCCGAGGGCGCCGCCGCCCCGCACGGGCGCACC
GTTCATGAGGCCCGCCCCATCGATCTGCCCTTGCCTGCGCGCCTCGATTTCGAGAGCGCCATCCTGAGCATCGAGGAGGT
GCCCGCCGATCCCGCCACCGTGCCGCTGGGCGAAGCGGATTTCGTGCTCTCGGCCGGCAATGGCGTCACGGATTTTGCCG
CCTTCGGCGCGCTGGCAGAGGCGCTCGGGGCGACGCCCGGAGCCAGCCGCATGGTGTGCGACGCCGGCCTCATGCCCCGC
GCCGCGCAGGTGGGCGCCTCGGGCACTGTGCTCTCGGCCCGCTGCTATTTCGCCCTCGGCATCGCCGGGGCGCCCCAGCA
TCTTCAGGGGATCGCCGGCTGCGAGCATGTGGTGGCGGTGAATACGGACCTGCATGCGGCGATGATCGAGCGCGCCGGGC
TCGCCGTGGTGGCGGACGCGCAGGCGGTCATGCCGGCGCTGCTCGCGCTCCTGGCGGAGGAGGCCTCATGA

Upstream 100 bases:

>100_bases
GGCCCGAAGTGCGGGATGTGGCCGAACTGGTGCTCGCCGCCGTCGAGGCGGGGCAAGCGGCCCCGGCATCCGCCGGCGCC
CGCCAGCCGGAGCCGGTCGC

Downstream 100 bases:

>100_bases
AGGCGCTGGTTCTGCTCTCCGAAAGCCGGCACCCCGTTTCCGGCAAGCCGTGCCTCTCCCGCTTGGAGGCGCAGGCGGCG
CGCATGGCGACGATCCTTGA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSRLRRDPRAERAARALPTQGRPRLQLGTPVSEGRLRRNPFAERAAAEVQGRTRLRLDRAGGGPRSVSVASPPAAPEPRA
PERRLVPEPAFLVLAVADVPGGHLSVHDRQVLGAARVLADAGGGAVVLLGGTLPQDAGAAGADRIACLPEADDPDRRAGA
LMAAIAALRPRHVLWPESRIGGDLARRVAVRIGEGLFCGAEQVSARAVARPARGRRVEQRREPPLLLTLAEGAAAPHGRT
VHEARPIDLPLPARLDFESAILSIEEVPADPATVPLGEADFVLSAGNGVTDFAAFGALAEALGATPGASRMVCDAGLMPR
AAQVGASGTVLSARCYFALGIAGAPQHLQGIAGCEHVVAVNTDLHAAMIERAGLAVVADAQAVMPALLALLAEEAS

Sequences:

>Translated_396_residues
MSRLRRDPRAERAARALPTQGRPRLQLGTPVSEGRLRRNPFAERAAAEVQGRTRLRLDRAGGGPRSVSVASPPAAPEPRA
PERRLVPEPAFLVLAVADVPGGHLSVHDRQVLGAARVLADAGGGAVVLLGGTLPQDAGAAGADRIACLPEADDPDRRAGA
LMAAIAALRPRHVLWPESRIGGDLARRVAVRIGEGLFCGAEQVSARAVARPARGRRVEQRREPPLLLTLAEGAAAPHGRT
VHEARPIDLPLPARLDFESAILSIEEVPADPATVPLGEADFVLSAGNGVTDFAAFGALAEALGATPGASRMVCDAGLMPR
AAQVGASGTVLSARCYFALGIAGAPQHLQGIAGCEHVVAVNTDLHAAMIERAGLAVVADAQAVMPALLALLAEEAS
>Mature_395_residues
SRLRRDPRAERAARALPTQGRPRLQLGTPVSEGRLRRNPFAERAAAEVQGRTRLRLDRAGGGPRSVSVASPPAAPEPRAP
ERRLVPEPAFLVLAVADVPGGHLSVHDRQVLGAARVLADAGGGAVVLLGGTLPQDAGAAGADRIACLPEADDPDRRAGAL
MAAIAALRPRHVLWPESRIGGDLARRVAVRIGEGLFCGAEQVSARAVARPARGRRVEQRREPPLLLTLAEGAAAPHGRTV
HEARPIDLPLPARLDFESAILSIEEVPADPATVPLGEADFVLSAGNGVTDFAAFGALAEALGATPGASRMVCDAGLMPRA
AQVGASGTVLSARCYFALGIAGAPQHLQGIAGCEHVVAVNTDLHAAMIERAGLAVVADAQAVMPALLALLAEEAS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=122, Percent_Identity=36.8852459016393, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503607, Length=122, Percent_Identity=36.8852459016393, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1787990, Length=257, Percent_Identity=28.7937743190661, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786226, Length=234, Percent_Identity=29.4871794871795, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082157, Length=223, Percent_Identity=29.5964125560538, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17506929, Length=119, Percent_Identity=38.655462184874, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325261, Length=260, Percent_Identity=26.1538461538462, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17136898, Length=115, Percent_Identity=36.5217391304348, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24652801, Length=115, Percent_Identity=36.5217391304348, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 40913; Mature: 40782

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLRRDPRAERAARALPTQGRPRLQLGTPVSEGRLRRNPFAERAAAEVQGRTRLRLDRA
CCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GGGPRSVSVASPPAAPEPRAPERRLVPEPAFLVLAVADVPGGHLSVHDRQVLGAARVLAD
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHC
AGGGAVVLLGGTLPQDAGAAGADRIACLPEADDPDRRAGALMAAIAALRPRHVLWPESRI
CCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHH
GGDLARRVAVRIGEGLFCGAEQVSARAVARPARGRRVEQRREPPLLLTLAEGAAAPHGRT
HHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCCCCC
VHEARPIDLPLPARLDFESAILSIEEVPADPATVPLGEADFVLSAGNGVTDFAAFGALAE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
ALGATPGASRMVCDAGLMPRAAQVGASGTVLSARCYFALGIAGAPQHLQGIAGCEHVVAV
HHCCCCCCCCEEECCCCCCCHHHCCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCEEEEE
NTDLHAAMIERAGLAVVADAQAVMPALLALLAEEAS
CCCHHHHHHHHCCEEEEECHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLRRDPRAERAARALPTQGRPRLQLGTPVSEGRLRRNPFAERAAAEVQGRTRLRLDRA
CCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GGGPRSVSVASPPAAPEPRAPERRLVPEPAFLVLAVADVPGGHLSVHDRQVLGAARVLAD
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHC
AGGGAVVLLGGTLPQDAGAAGADRIACLPEADDPDRRAGALMAAIAALRPRHVLWPESRI
CCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHH
GGDLARRVAVRIGEGLFCGAEQVSARAVARPARGRRVEQRREPPLLLTLAEGAAAPHGRT
HHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCCCCC
VHEARPIDLPLPARLDFESAILSIEEVPADPATVPLGEADFVLSAGNGVTDFAAFGALAE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
ALGATPGASRMVCDAGLMPRAAQVGASGTVLSARCYFALGIAGAPQHLQGIAGCEHVVAV
HHCCCCCCCCEEECCCCCCCHHHCCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCEEEEE
NTDLHAAMIERAGLAVVADAQAVMPALLALLAEEAS
CCCHHHHHHHHCCEEEEECHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]