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The map label for this gene is evgS [C]

Identifier: 158422717

GI number: 158422717

Start: 1219866

End: 1221527

Strand: Direct

Name: evgS [C]

Synonym: AZC_1093

Alternate gene names: 158422717

Gene position: 1219866-1221527 (Clockwise)

Preceding gene: 158422714

Following gene: 158422718

Centisome position: 22.72

GC content: 70.34

Gene sequence:

>1662_bases
TTGAAAGTAGCAAAGCCGGGCGCGCGGGGCAGCGGCGGGGACCCGTTTGCCACCGCTTCTTTTCAAGACATCGTTAACGC
TGATCGCGTCCGTGATGGCGCTGCGCGCTTAGCCTTCCTTAAAGCCTTCCGTGTCAGGCTCTCTCCCATCGTCATGCAAG
GGCGCCGCGGGCGCCGGTCGCACGGTGGGCACATGGATTGGGTCTTGAGCGATCAACGGCAGGGTGCAGGCAGCCTCAAC
GCGCAGCCGGACGCGGCGCGATCCGGTCGCGTCCGCACGTCGCTGCGTGATCTGGCCGGGGTCGGCCGCCACAGCGCCGC
CGCGCTTGGGGCGCTGGCCTTCATGTGCGCGCTCGCCGGCGGCGGGCTGCTGCTGGCGGCGGCGCTCGGGCTCTCGGAGA
CCGGCCTGCCGGAAGGCGGCTGGCTGCTCGGCTGCGGCCTCATCAGCGCCGCTCTGTCCGCCGTCGCCGCTGGCCTGTCT
CTGGCGGCCGAGCGGCTCGACCGTTCCATGATGGGCGTCGATCTGGCGCTCGTCACCCTGCACGGGCGGGGCGGCGAGGT
GCTGGGGCTGGAGCATGCGGATGCCGCCCGCGCCCATGTGCCGGAGGATGCCTGGCTGGGGCAGGGCCTGTTCGACCGCG
TGCTGGTGCCCGATCGGCCGGCCTTCCTCGCGGCCCTCTCCACGGCCGCCCACGGCCTTTCCGCCACCGAGAGCGTGTGC
GAGGTGCGCCTGCGTTGCGAGGGCGAGGGCGAGGCCCCCGATTTCGTGTGGATGGAACTGCGTTGCGTCCCGGCTGGCGA
GGACCGCGCCCGCGCGCACTGGCGCGACATCCATGCGGTGAAGATACAGCTGGAAGAGGATCACCGCGCCCGCACCGAGG
CGGAGCGGGCGAACCTCGCCAAGAGCCGCTTCCTCGCCGCGATGAGCCATGAACTGCGCACGCCGCTCAACACCATCCTC
GGCTTTTCCGAACTGCTCGCCACCGACACCGAGCAGCGTATCGATGCCCGCCGCAAGGAAGACTATGCCCGCATCATCCA
CGAGAGCGGCCAGCATCTCCTCGGTGTCGTGAACGACATCCTCGACCTGTCGCGGGTGGAGGCGGGGGCCTATGAGCTTT
CCTTCGAGCACATCGACATGGCCCATCTGGTGGATGGCTGCGTGGAGATGGTCGGCCTCGATGCCGCCCGCCGCAACATC
AAGGTGACGACGCTTCTGCCCGCCCGCCTGCCGCGCCCCATGGCCGACCAGCGGGCCGTGCGCCAGATGACGCTGAACCT
GCTTTCCAATGCCGTGAAGTTCTCCGAGCACGGCGGCCTCGTGGAAGTGAATGTCTCGGCCCAGAACGGCGTCGTGTCCC
TGAGCGTGCGCGACAGCGGCGCCGGCATGTCGCCGGCCGAGGTGGAGCGGCTCGGGGAGCCCTTCTTCCAGGCGGGCGAC
GCGGAGCGCCGCGCGCGGGGCAGCGGCCTCGGCCTTGCCGTGGTGCGCGCCCTCGTGAAGCTGCATGACGGTGCCTTCGA
GGTGACGAGCAGCGTCGGCGGCGGCACCACCGTCACCATCAGCCTGCCGGTGCGGCGGTCGTCGGGCGTTGTTTCGCCCT
TCGCGCGGGCCATCACCGATGAGGCCGGCCGCAAGGACAATGAGGGGCGCCGGATCGCATGA

Upstream 100 bases:

>100_bases
AGGATCAGAAGGATGAGGGCCAGCCAGAAGGCCATTCGCAGCAGGAAGAACATCCGATCCTCACGGCCCCGGCCAGCCTC
CTGAGGCCGGGCGCTTACCC

Downstream 100 bases:

>100_bases
GGCTCGCATTCTGGCGCCCGGCCGAGACCGAGGCGGATGACCTTGCCGGTGCCGGCGCGTTCGAGGCGTTCAAGGCCGAG
CGCAGCCTGAAGCGGCGGCG

Product: sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MKVAKPGARGSGGDPFATASFQDIVNADRVRDGAARLAFLKAFRVRLSPIVMQGRRGRRSHGGHMDWVLSDQRQGAGSLN
AQPDAARSGRVRTSLRDLAGVGRHSAAALGALAFMCALAGGGLLLAAALGLSETGLPEGGWLLGCGLISAALSAVAAGLS
LAAERLDRSMMGVDLALVTLHGRGGEVLGLEHADAARAHVPEDAWLGQGLFDRVLVPDRPAFLAALSTAAHGLSATESVC
EVRLRCEGEGEAPDFVWMELRCVPAGEDRARAHWRDIHAVKIQLEEDHRARTEAERANLAKSRFLAAMSHELRTPLNTIL
GFSELLATDTEQRIDARRKEDYARIIHESGQHLLGVVNDILDLSRVEAGAYELSFEHIDMAHLVDGCVEMVGLDAARRNI
KVTTLLPARLPRPMADQRAVRQMTLNLLSNAVKFSEHGGLVEVNVSAQNGVVSLSVRDSGAGMSPAEVERLGEPFFQAGD
AERRARGSGLGLAVVRALVKLHDGAFEVTSSVGGGTTVTISLPVRRSSGVVSPFARAITDEAGRKDNEGRRIA

Sequences:

>Translated_553_residues
MKVAKPGARGSGGDPFATASFQDIVNADRVRDGAARLAFLKAFRVRLSPIVMQGRRGRRSHGGHMDWVLSDQRQGAGSLN
AQPDAARSGRVRTSLRDLAGVGRHSAAALGALAFMCALAGGGLLLAAALGLSETGLPEGGWLLGCGLISAALSAVAAGLS
LAAERLDRSMMGVDLALVTLHGRGGEVLGLEHADAARAHVPEDAWLGQGLFDRVLVPDRPAFLAALSTAAHGLSATESVC
EVRLRCEGEGEAPDFVWMELRCVPAGEDRARAHWRDIHAVKIQLEEDHRARTEAERANLAKSRFLAAMSHELRTPLNTIL
GFSELLATDTEQRIDARRKEDYARIIHESGQHLLGVVNDILDLSRVEAGAYELSFEHIDMAHLVDGCVEMVGLDAARRNI
KVTTLLPARLPRPMADQRAVRQMTLNLLSNAVKFSEHGGLVEVNVSAQNGVVSLSVRDSGAGMSPAEVERLGEPFFQAGD
AERRARGSGLGLAVVRALVKLHDGAFEVTSSVGGGTTVTISLPVRRSSGVVSPFARAITDEAGRKDNEGRRIA
>Mature_553_residues
MKVAKPGARGSGGDPFATASFQDIVNADRVRDGAARLAFLKAFRVRLSPIVMQGRRGRRSHGGHMDWVLSDQRQGAGSLN
AQPDAARSGRVRTSLRDLAGVGRHSAAALGALAFMCALAGGGLLLAAALGLSETGLPEGGWLLGCGLISAALSAVAAGLS
LAAERLDRSMMGVDLALVTLHGRGGEVLGLEHADAARAHVPEDAWLGQGLFDRVLVPDRPAFLAALSTAAHGLSATESVC
EVRLRCEGEGEAPDFVWMELRCVPAGEDRARAHWRDIHAVKIQLEEDHRARTEAERANLAKSRFLAAMSHELRTPLNTIL
GFSELLATDTEQRIDARRKEDYARIIHESGQHLLGVVNDILDLSRVEAGAYELSFEHIDMAHLVDGCVEMVGLDAARRNI
KVTTLLPARLPRPMADQRAVRQMTLNLLSNAVKFSEHGGLVEVNVSAQNGVVSLSVRDSGAGMSPAEVERLGEPFFQAGD
AERRARGSGLGLAVVRALVKLHDGAFEVTSSVGGGTTVTISLPVRRSSGVVSPFARAITDEAGRKDNEGRRIA

Specific function: Member Of The Two-Component Regulatory System Evgs/Evga. Phosphorylates Evga Via A Four-Step Phosphorelay In Response To Environmental Signals. [C]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=292, Percent_Identity=33.9041095890411, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=36.4, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI48994928, Length=329, Percent_Identity=32.2188449848024, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=33.0677290836653, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=32.6848249027237, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=29.7520661157025, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=30.1652892561983, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=29.8319327731092, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=29.2592592592593, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.0334728033473, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=25.6198347107438, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=27.7056277056277, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=27.3127753303965, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=221, Percent_Identity=29.8642533936652, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=24.8031496062992, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=25.4545454545455, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=23.7885462555066, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58824; Mature: 58824

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAKPGARGSGGDPFATASFQDIVNADRVRDGAARLAFLKAFRVRLSPIVMQGRRGRRS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HGGHMDWVLSDQRQGAGSLNAQPDAARSGRVRTSLRDLAGVGRHSAAALGALAFMCALAG
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
GGLLLAAALGLSETGLPEGGWLLGCGLISAALSAVAAGLSLAAERLDRSMMGVDLALVTL
CHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
HGRGGEVLGLEHADAARAHVPEDAWLGQGLFDRVLVPDRPAFLAALSTAAHGLSATESVC
ECCCCCEEECCCCCCHHHCCCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
EVRLRCEGEGEAPDFVWMELRCVPAGEDRARAHWRDIHAVKIQLEEDHRARTEAERANLA
HEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHH
KSRFLAAMSHELRTPLNTILGFSELLATDTEQRIDARRKEDYARIIHESGQHLLGVVNDI
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LDLSRVEAGAYELSFEHIDMAHLVDGCVEMVGLDAARRNIKVTTLLPARLPRPMADQRAV
HHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHCCHHHHCCEEEEEEEHHHCCCCCHHHHHH
RQMTLNLLSNAVKFSEHGGLVEVNVSAQNGVVSLSVRDSGAGMSPAEVERLGEPFFQAGD
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCHHHHCCC
AERRARGSGLGLAVVRALVKLHDGAFEVTSSVGGGTTVTISLPVRRSSGVVSPFARAITD
HHHHHCCCCCHHHHHHHHHHHCCCHHEEHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EAGRKDNEGRRIA
HCCCCCCCCCCCC
>Mature Secondary Structure
MKVAKPGARGSGGDPFATASFQDIVNADRVRDGAARLAFLKAFRVRLSPIVMQGRRGRRS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HGGHMDWVLSDQRQGAGSLNAQPDAARSGRVRTSLRDLAGVGRHSAAALGALAFMCALAG
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
GGLLLAAALGLSETGLPEGGWLLGCGLISAALSAVAAGLSLAAERLDRSMMGVDLALVTL
CHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
HGRGGEVLGLEHADAARAHVPEDAWLGQGLFDRVLVPDRPAFLAALSTAAHGLSATESVC
ECCCCCEEECCCCCCHHHCCCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
EVRLRCEGEGEAPDFVWMELRCVPAGEDRARAHWRDIHAVKIQLEEDHRARTEAERANLA
HEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHH
KSRFLAAMSHELRTPLNTILGFSELLATDTEQRIDARRKEDYARIIHESGQHLLGVVNDI
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LDLSRVEAGAYELSFEHIDMAHLVDGCVEMVGLDAARRNIKVTTLLPARLPRPMADQRAV
HHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHCCHHHHCCEEEEEEEHHHCCCCCHHHHHH
RQMTLNLLSNAVKFSEHGGLVEVNVSAQNGVVSLSVRDSGAGMSPAEVERLGEPFFQAGD
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCHHHHCCC
AERRARGSGLGLAVVRALVKLHDGAFEVTSSVGGGTTVTISLPVRRSSGVVSPFARAITD
HHHHHCCCCCHHHHHHHHHHHCCCHHEEHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EAGRKDNEGRRIA
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 7756693 [H]