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The map label for this gene is lysR [H]

Identifier: 158422703

GI number: 158422703

Start: 1207923

End: 1208861

Strand: Reverse

Name: lysR [H]

Synonym: AZC_1079

Alternate gene names: 158422703

Gene position: 1208861-1207923 (Counterclockwise)

Preceding gene: 158422704

Following gene: 158422696

Centisome position: 22.51

GC content: 68.26

Gene sequence:

>939_bases
ATGATCGACAAACTTGAATATCTCATTGCTCTGGCCCGCGAACGGCACTTCGGCCGGGCGGCGGAAGCCTGCGGCGTGAC
GCAGCCGACACTGTCGGCCGGCATCAAGCAACTGGAGGATACGCTCGGCGTACTGCTGGTGCAGCGGGGCTCGCGCTTCA
TGGGCTTCACGCCCGAGGGCGAGCGCACGCTGGAATGGGCCCGCCGCATCGTGGCCGACAGCCGCGCCATGCGGCAGGAC
ATCGACGCGCTCAAGCGCGGCCTGTCCGGCCCGCTGCGCATCGCCGCCATCCCCACCGCTCTGCCCATGGTGGCGGCGCT
GACCACACCCTTCCGCGCCCGTCATCCGGACGTGCGCTTCACCGTCATCTCCTCGACCTCCATCGAGATCCTCAACCATC
TCGAGAATCTGGAGATCGACGCCGGCCTCACCTATCTCGACAACGAGCCGCTCGGCCGCGTGAATACCGTGCCGCTCTAT
CGCGAGCGCTACCGTCTCGTGACCTCGCCGGGCGCCAAATATGGCGACCGCGAGCAGGTGACGTGGGCGGAAATCGCCGA
ATTGCCGCTCTGCCTGCTGACGCCCGACATGCAGAACCGCCGCATCGTGGACGGACTGCTCGCCGCCTCCGGCGCGGTGC
AGAAGCCGACGCTGGAGAGCAATTCCATGATCGTGCTCTTCACCCATGTGCGCACGGGCCAGTGGTCCAGCGTCATGCCG
GCGATGCTCGCGGATTCCCTCGGCCTCACCTCCGAGCTGCGCTCCATCCCCATTGTCGAGCCGGAGATCACCCACTCCAT
CGGCCTCGTGGTGCCCCACCGCGAGCCGACCACGCCCCTCACCGCCGCCCTCGTGGCCGAGGCCCGGCGCATCGCGCCGC
GGCTCAACCAGGATCTCGGCATGGGCCGCGATCCTGCCCTGGCGACGCTCACGCCCTGA

Upstream 100 bases:

>100_bases
TGCACCGAAGGCTCGTCGCACCGCGCCCACGGAAGGCCGAGCTTGCGGCCGATGGAATTCCCTGCGAGGGATAGACCGAG
GCAGTGTTCCGAGTGGCCGG

Downstream 100 bases:

>100_bases
ACGACGAAAGGCCGGGCGGGTTCAGCCAGCCCGCCCGGCCTTTTCGTTATTCCGACGGTCTGACGCTCAGGCCGCGCGGA
TGGTGGCGAGGAAGCTCTTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MIDKLEYLIALARERHFGRAAEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEGERTLEWARRIVADSRAMRQD
IDALKRGLSGPLRIAAIPTALPMVAALTTPFRARHPDVRFTVISSTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLY
RERYRLVTSPGAKYGDREQVTWAEIAELPLCLLTPDMQNRRIVDGLLAASGAVQKPTLESNSMIVLFTHVRTGQWSSVMP
AMLADSLGLTSELRSIPIVEPEITHSIGLVVPHREPTTPLTAALVAEARRIAPRLNQDLGMGRDPALATLTP

Sequences:

>Translated_312_residues
MIDKLEYLIALARERHFGRAAEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEGERTLEWARRIVADSRAMRQD
IDALKRGLSGPLRIAAIPTALPMVAALTTPFRARHPDVRFTVISSTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLY
RERYRLVTSPGAKYGDREQVTWAEIAELPLCLLTPDMQNRRIVDGLLAASGAVQKPTLESNSMIVLFTHVRTGQWSSVMP
AMLADSLGLTSELRSIPIVEPEITHSIGLVVPHREPTTPLTAALVAEARRIAPRLNQDLGMGRDPALATLTP
>Mature_312_residues
MIDKLEYLIALARERHFGRAAEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEGERTLEWARRIVADSRAMRQD
IDALKRGLSGPLRIAAIPTALPMVAALTTPFRARHPDVRFTVISSTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLY
RERYRLVTSPGAKYGDREQVTWAEIAELPLCLLTPDMQNRRIVDGLLAASGAVQKPTLESNSMIVLFTHVRTGQWSSVMP
AMLADSLGLTSELRSIPIVEPEITHSIGLVVPHREPTTPLTAALVAEARRIAPRLNQDLGMGRDPALATLTP

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=296, Percent_Identity=29.7297297297297, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=28.8065843621399, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786401, Length=182, Percent_Identity=31.3186813186813, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787879, Length=290, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=242, Percent_Identity=23.5537190082645, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=23.8095238095238, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI2367136, Length=147, Percent_Identity=31.9727891156463, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788296, Length=231, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081904, Length=211, Percent_Identity=27.9620853080569, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788887, Length=146, Percent_Identity=30.8219178082192, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34263; Mature: 34263

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKLEYLIALARERHFGRAAEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEG
CCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
ERTLEWARRIVADSRAMRQDIDALKRGLSGPLRIAAIPTALPMVAALTTPFRARHPDVRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCEEE
TVISSTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLYRERYRLVTSPGAKYGDREQV
EEECCCHHHHHHHHHCCEECCCCEEECCCCCCCCCCCCHHHHHHHEEECCCCCCCCCCCC
TWAEIAELPLCLLTPDMQNRRIVDGLLAASGAVQKPTLESNSMIVLFTHVRTGQWSSVMP
HHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHH
AMLADSLGLTSELRSIPIVEPEITHSIGLVVPHREPTTPLTAALVAEARRIAPRLNQDLG
HHHHHHCCCHHHHHCCCCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
MGRDPALATLTP
CCCCCCEEECCC
>Mature Secondary Structure
MIDKLEYLIALARERHFGRAAEACGVTQPTLSAGIKQLEDTLGVLLVQRGSRFMGFTPEG
CCHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
ERTLEWARRIVADSRAMRQDIDALKRGLSGPLRIAAIPTALPMVAALTTPFRARHPDVRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCEEE
TVISSTSIEILNHLENLEIDAGLTYLDNEPLGRVNTVPLYRERYRLVTSPGAKYGDREQV
EEECCCHHHHHHHHHCCEECCCCEEECCCCCCCCCCCCHHHHHHHEEECCCCCCCCCCCC
TWAEIAELPLCLLTPDMQNRRIVDGLLAASGAVQKPTLESNSMIVLFTHVRTGQWSSVMP
HHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHHH
AMLADSLGLTSELRSIPIVEPEITHSIGLVVPHREPTTPLTAALVAEARRIAPRLNQDLG
HHHHHHCCCHHHHHCCCCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
MGRDPALATLTP
CCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA