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The map label for this gene is trpB [H]

Identifier: 158422642

GI number: 158422642

Start: 1142999

End: 1144210

Strand: Direct

Name: trpB [H]

Synonym: AZC_1018

Alternate gene names: 158422642

Gene position: 1142999-1144210 (Clockwise)

Preceding gene: 158422641

Following gene: 158422643

Centisome position: 21.29

GC content: 65.1

Gene sequence:

>1212_bases
GTGAACGCGCTCAATTCCTATCGCACCGGCCCCGACGAGAACGGCCATTTCGGCATCCATGGCGGACGTTTCGTCGCCGA
GACCCTGATGCCGAACATTCTCGAACTGCAGGCGGCCTATGAGGCGGCCAAGGCCGACCCGGCCTATCAGTCCGAGATGG
CCGGCTACCTTGCCCATTATGTGGGGCGACCCTCGCCGCTCTATTATGCCGAGCGCCTGTCCGAGCATCTCGGCGGCGCG
AAGATCTATCTGAAGCGCGAGGAGCTGAACCACACCGGCTCTCACAAGGTGAACAACGTGCTCGGCCAGATCCTGCTGGC
CCTGCGCATGGGCAAGAAGCGCATCATTGCCGAGACCGGCGCCGGCCAGCACGGCGTCGCCACCGCGACGCTCTGCGCCC
GCTTCGGCCTGAAGTGCATCGTGTACATGGGCGCGGTGGACGTGGAGCGGCAGAAGCCGAACGTCTTCCGCATGAACATG
CTGGGCGCCGAGGTGGTGCCCGTGCAGTCCGGCTCGCGCACCCTGAAGGACGCCATGAACGAGGCGCTGCGCGACTGGGT
GACCAATGTGCACGACACCTTCTATTGCATCGGTACGGTGGCGGGCCCGCATCCCTATCCGTCCATGGTGCGCGACTTCC
AGTCCATCATCGGCCGCGAGACCCGCGAGCAGCTGATGGAAGCCGAAGGCCGCGGCCCGGACAGCCTGATCGCGGCGGTG
GGCGGCGGCTCGAACGCCATCGGCCTGTTCCACGAATTCCTCGACGACAGCGGTGTCGAGATCTACGGCGTCGAGGCGGC
CGGCCACGGCATCTCCTCGGGCATGCACGCCGCCTCCATCACCGGCGGCAAGCCGGGCGTGCTGCACGGCAACCGCACCT
ATCTCCTGATGGATGACGACGGCCAGATCATTGAGGCCCATTCCATCTCCGCCGGCCTCGACTATCCGGGCATCGGGCCG
GAGCATTCCTGGCTGCACGATACGGGGCGGGTGACCTACATTCCCTGCACCGACAAGGAGGCTCTCGAGGGCTTCCAGCT
TCTCTCCCGTCTCGAAGGCATCATCCCGGCGCTGGAATGCGCCCATGCCATCGGGAAGGTGATGGAGATCGCACCGACCA
AGCCGAAGGACCATCTGATGGTGGTCAATCTGTCCGGCCGCGGCGATAAGGACATCTTCACTGTGGCCGAACATCTGGGG
GGCCAGATATGA

Upstream 100 bases:

>100_bases
CCGGCCTGAAATCGCCGGAAAAGATCCTGGCCTTCGTCCGTGCGGTGAAGGCTGCCGAGGCGGCATCGCGGCCGTCGCGC
CTGAAGAAAGTCGAAGCTCC

Downstream 100 bases:

>100_bases
AGCGTATGGTCGTTGCTTTCCTCGCGCTCGGCGTTGCGGGGGCCGTCGTGCCCGCCTTCGCCCAGCAGCCGCCGCAGCCT
GCCAACCTGCAACTGCAGGT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNALNSYRTGPDENGHFGIHGGRFVAETLMPNILELQAAYEAAKADPAYQSEMAGYLAHYVGRPSPLYYAERLSEHLGGA
KIYLKREELNHTGSHKVNNVLGQILLALRMGKKRIIAETGAGQHGVATATLCARFGLKCIVYMGAVDVERQKPNVFRMNM
LGAEVVPVQSGSRTLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPSMVRDFQSIIGRETREQLMEAEGRGPDSLIAAV
GGGSNAIGLFHEFLDDSGVEIYGVEAAGHGISSGMHAASITGGKPGVLHGNRTYLLMDDDGQIIEAHSISAGLDYPGIGP
EHSWLHDTGRVTYIPCTDKEALEGFQLLSRLEGIIPALECAHAIGKVMEIAPTKPKDHLMVVNLSGRGDKDIFTVAEHLG
GQI

Sequences:

>Translated_403_residues
MNALNSYRTGPDENGHFGIHGGRFVAETLMPNILELQAAYEAAKADPAYQSEMAGYLAHYVGRPSPLYYAERLSEHLGGA
KIYLKREELNHTGSHKVNNVLGQILLALRMGKKRIIAETGAGQHGVATATLCARFGLKCIVYMGAVDVERQKPNVFRMNM
LGAEVVPVQSGSRTLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPSMVRDFQSIIGRETREQLMEAEGRGPDSLIAAV
GGGSNAIGLFHEFLDDSGVEIYGVEAAGHGISSGMHAASITGGKPGVLHGNRTYLLMDDDGQIIEAHSISAGLDYPGIGP
EHSWLHDTGRVTYIPCTDKEALEGFQLLSRLEGIIPALECAHAIGKVMEIAPTKPKDHLMVVNLSGRGDKDIFTVAEHLG
GQI
>Mature_403_residues
MNALNSYRTGPDENGHFGIHGGRFVAETLMPNILELQAAYEAAKADPAYQSEMAGYLAHYVGRPSPLYYAERLSEHLGGA
KIYLKREELNHTGSHKVNNVLGQILLALRMGKKRIIAETGAGQHGVATATLCARFGLKCIVYMGAVDVERQKPNVFRMNM
LGAEVVPVQSGSRTLKDAMNEALRDWVTNVHDTFYCIGTVAGPHPYPSMVRDFQSIIGRETREQLMEAEGRGPDSLIAAV
GGGSNAIGLFHEFLDDSGVEIYGVEAAGHGISSGMHAASITGGKPGVLHGNRTYLLMDDDGQIIEAHSISAGLDYPGIGP
EHSWLHDTGRVTYIPCTDKEALEGFQLLSRLEGIIPALECAHAIGKVMEIAPTKPKDHLMVVNLSGRGDKDIFTVAEHLG
GQI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=383, Percent_Identity=54.0469973890339, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=55.5844155844156, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43495; Mature: 43495

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALNSYRTGPDENGHFGIHGGRFVAETLMPNILELQAAYEAAKADPAYQSEMAGYLAHY
CCCCCCCCCCCCCCCEECCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VGRPSPLYYAERLSEHLGGAKIYLKREELNHTGSHKVNNVLGQILLALRMGKKRIIAETG
HCCCCCHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCHHEEEECC
AGQHGVATATLCARFGLKCIVYMGAVDVERQKPNVFRMNMLGAEVVPVQSGSRTLKDAMN
CCCCCHHHHHHHHHHCCCEEEEECCEECCCCCCCEEEEEECCCEEEECCCCCHHHHHHHH
EALRDWVTNVHDTFYCIGTVAGPHPYPSMVRDFQSIIGRETREQLMEAEGRGPDSLIAAV
HHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEE
GGGSNAIGLFHEFLDDSGVEIYGVEAAGHGISSGMHAASITGGKPGVLHGNRTYLLMDDD
CCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCEEECCEEEEEECCC
GQIIEAHSISAGLDYPGIGPEHSWLHDTGRVTYIPCTDKEALEGFQLLSRLEGIIPALEC
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AHAIGKVMEIAPTKPKDHLMVVNLSGRGDKDIFTVAEHLGGQI
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNALNSYRTGPDENGHFGIHGGRFVAETLMPNILELQAAYEAAKADPAYQSEMAGYLAHY
CCCCCCCCCCCCCCCEECCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VGRPSPLYYAERLSEHLGGAKIYLKREELNHTGSHKVNNVLGQILLALRMGKKRIIAETG
HCCCCCHHHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHCCHHEEEECC
AGQHGVATATLCARFGLKCIVYMGAVDVERQKPNVFRMNMLGAEVVPVQSGSRTLKDAMN
CCCCCHHHHHHHHHHCCCEEEEECCEECCCCCCCEEEEEECCCEEEECCCCCHHHHHHHH
EALRDWVTNVHDTFYCIGTVAGPHPYPSMVRDFQSIIGRETREQLMEAEGRGPDSLIAAV
HHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEE
GGGSNAIGLFHEFLDDSGVEIYGVEAAGHGISSGMHAASITGGKPGVLHGNRTYLLMDDD
CCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCEEECCEEEEEECCC
GQIIEAHSISAGLDYPGIGPEHSWLHDTGRVTYIPCTDKEALEGFQLLSRLEGIIPALEC
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AHAIGKVMEIAPTKPKDHLMVVNLSGRGDKDIFTVAEHLGGQI
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA