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The map label for this gene is lysR [H]

Identifier: 158422589

GI number: 158422589

Start: 1075985

End: 1076773

Strand: Reverse

Name: lysR [H]

Synonym: AZC_0965

Alternate gene names: 158422589

Gene position: 1076773-1075985 (Counterclockwise)

Preceding gene: 158422591

Following gene: 158422588

Centisome position: 20.05

GC content: 69.07

Gene sequence:

>789_bases
ATGGCGGCCTCCCGCCACCTCGCGACGCTGGAGCAGGAACTGGGCGTCCGCCTCGTCCACCGCACCACGCGGGCCCTGAC
GCTGACGGACGAAGGGCAGGTCTTCCTGCCCCATGCGCAGACGCTGCTGGAGGAAAAGGCGGCGGCAATCGCCAGCATCT
GCTCGCCCGAGGACAAGGCGACCGGCCTCCTGCGCCTCTCCTGCTCGGCCGCCTTCGCCCGGCGCATCATCAATCCCGTG
GTGGCCCATTTCATGGAGGCCAACCCGCAGGTTCGCGTGGATGTGATGATCTCCGACACCGTCGTCGACGTGGTGGCGGA
AGGCATCGATCTGGCCATCCGCATTGCGCAGCTCGGCGACAGCACCCTGATCGCCCGCCGCCTTGCCGACAACCCCTGCC
TGCTGATCGCCTCCCCCGCCTATCTCGCCCGGCACGGACGGCCGCAGACGATGGCGGACCTCAAGACCCACGAATGCCTC
ACCACGCCCAACCGCAGCCACTGGACCTTCGCCAGCGAGGGCCGCAGCGTGCGCGTGAAGGCGAGCGGGCGCTACAGTTC
GTCCTCGATGGAATCGCTGCACCAGGCCTGCATCGCCGGCCTCGGCATCGCCAACCTCTCCCTCTGGAACGTGCGCGAGG
AAATCGCGGATGGGCGTCTGGAGGCGATCCACCTGTCGGACGGCGAGCCGGAAACGCTCGCCATCTGGGCGGTCTACCCC
ACGCGGCGGCTCGTGCCCGCCAAGGTGCGATTGTTCATCGAGGCGCTCTCGGCGCGGCTGCGGGCCTGA

Upstream 100 bases:

>100_bases
AAGGTTTGATACAATGGAATTCATCGCCCTTTCCGTGCTCGCCGAGACGGCCGCCGCCGGCAGCCTTGCCGCCGCGGCCC
GGCGTCTGCGCATCTCGCCC

Downstream 100 bases:

>100_bases
GCGTGGGCGGACGATGGTTGTTCGCTTCCGCCGATTGGCTTAGCCTTTGGCAAAACGAACGTGGGAGGGTCGCATGTGCC
ACATGTTCGCACATCAGCCC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MAASRHLATLEQELGVRLVHRTTRALTLTDEGQVFLPHAQTLLEEKAAAIASICSPEDKATGLLRLSCSAAFARRIINPV
VAHFMEANPQVRVDVMISDTVVDVVAEGIDLAIRIAQLGDSTLIARRLADNPCLLIASPAYLARHGRPQTMADLKTHECL
TTPNRSHWTFASEGRSVRVKASGRYSSSSMESLHQACIAGLGIANLSLWNVREEIADGRLEAIHLSDGEPETLAIWAVYP
TRRLVPAKVRLFIEALSARLRA

Sequences:

>Translated_262_residues
MAASRHLATLEQELGVRLVHRTTRALTLTDEGQVFLPHAQTLLEEKAAAIASICSPEDKATGLLRLSCSAAFARRIINPV
VAHFMEANPQVRVDVMISDTVVDVVAEGIDLAIRIAQLGDSTLIARRLADNPCLLIASPAYLARHGRPQTMADLKTHECL
TTPNRSHWTFASEGRSVRVKASGRYSSSSMESLHQACIAGLGIANLSLWNVREEIADGRLEAIHLSDGEPETLAIWAVYP
TRRLVPAKVRLFIEALSARLRA
>Mature_261_residues
AASRHLATLEQELGVRLVHRTTRALTLTDEGQVFLPHAQTLLEEKAAAIASICSPEDKATGLLRLSCSAAFARRIINPVV
AHFMEANPQVRVDVMISDTVVDVVAEGIDLAIRIAQLGDSTLIARRLADNPCLLIASPAYLARHGRPQTMADLKTHECLT
TPNRSHWTFASEGRSVRVKASGRYSSSSMESLHQACIAGLGIANLSLWNVREEIADGRLEAIHLSDGEPETLAIWAVYPT
RRLVPAKVRLFIEALSARLRA

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=264, Percent_Identity=37.5, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI87081978, Length=257, Percent_Identity=36.9649805447471, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789639, Length=260, Percent_Identity=30.3846153846154, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789440, Length=259, Percent_Identity=30.1158301158301, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI145693193, Length=265, Percent_Identity=30.5660377358491, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787128, Length=258, Percent_Identity=27.1317829457364, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787589, Length=264, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789173, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786448, Length=219, Percent_Identity=26.4840182648402, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=26.4044943820225, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 28598; Mature: 28467

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASRHLATLEQELGVRLVHRTTRALTLTDEGQVFLPHAQTLLEEKAAAIASICSPEDKA
CCCCHHHHHHHHHHCHHEEEECCEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCC
TGLLRLSCSAAFARRIINPVVAHFMEANPQVRVDVMISDTVVDVVAEGIDLAIRIAQLGD
CEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHCCHHHEEEEECCCC
STLIARRLADNPCLLIASPAYLARHGRPQTMADLKTHECLTTPNRSHWTFASEGRSVRVK
HHHHHHHHCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCEEEEE
ASGRYSSSSMESLHQACIAGLGIANLSLWNVREEIADGRLEAIHLSDGEPETLAIWAVYP
ECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECC
TRRLVPAKVRLFIEALSARLRA
CCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASRHLATLEQELGVRLVHRTTRALTLTDEGQVFLPHAQTLLEEKAAAIASICSPEDKA
CCCHHHHHHHHHHCHHEEEECCEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCC
TGLLRLSCSAAFARRIINPVVAHFMEANPQVRVDVMISDTVVDVVAEGIDLAIRIAQLGD
CEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHCCHHHEEEEECCCC
STLIARRLADNPCLLIASPAYLARHGRPQTMADLKTHECLTTPNRSHWTFASEGRSVRVK
HHHHHHHHCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCEEEEE
ASGRYSSSSMESLHQACIAGLGIANLSLWNVREEIADGRLEAIHLSDGEPETLAIWAVYP
ECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECC
TRRLVPAKVRLFIEALSARLRA
CCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]