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The map label for this gene is nhaA [H]

Identifier: 158422526

GI number: 158422526

Start: 1010717

End: 1011607

Strand: Reverse

Name: nhaA [H]

Synonym: AZC_0902

Alternate gene names: 158422526

Gene position: 1011607-1010717 (Counterclockwise)

Preceding gene: 158422527

Following gene: 158422525

Centisome position: 18.84

GC content: 68.91

Gene sequence:

>891_bases
ATGTCGGATGATCTGATCGCAGCCGCAAAGCGGCGTTTCACGGACCTCCTGCCGCAGAGCTGGCGGCGGGATCTCACCCT
GGTGCCGGTGGTGCGCCTCTCAGGCGCCATCGGCATGAACTCGCCCTTCCGCCAGAGCCTCACGCTCGCCGCCACAGCGC
GCCTGCTGGACCGGGCCTTCGCGGTAAAGCGGGCACCGGCGGTGGCCCTGGTCATCAATTCGCCGGGCGGCTCGCCCGTG
CAGTCGAACCTCATCTTCAAGCGCATCCGGGCTCTGGCCGAGGAGAAGAACAAGCGCGTCTTCGCCTTCGTGGAGGATGT
GGCGGCCTCCGGCGGCTACATGCTCGCCTGCGCGGCGGACGAGATCTATGCCGATCCCTCTTCCATCGTCGGTTCCATCG
GCGTCGTCTCGGCAGGCTTCGGCTTCAACGACATGCTCTCGCGCATCGGCGTGGAGCGGCGCGTCCACACCGCCGGGACC
CGCAAGGTGATGCTCGATCCCTTCCAGCCCGAGCGGGCGGAGGATGTGGACCGCCTGCTCGCCATCCAGCGGGAGGTCCA
TGCCTCCTTCCGCGATCTCGTGCGCAGCCGGCGCGGGGCGCTGCTGAAAGGCGAGGAGGACGATCTCTTCTCCGGCGAGT
TCTGGGTGGGCGCACAGGCGCTCCCCATGGGCCTTATCGACGGACTGGGCGATCTGCGCAGCGTGCTGCGGGAGCGTTTC
GGCACCGATGTGCGCACGCCGCTCATCGCCCCGTCCGGCAACTGGTTCACCCGCCGGGCCAACGGCATCGGCGCGCAGAT
CGGTCTCGACGGCGGGATCGGTGCCGGCTTCGCGCAGGGCCTTGCGGATGTGGCCGAAGAGCGGGCGCTCTGGGCGCGCT
ACGGACTTTGA

Upstream 100 bases:

>100_bases
AAGGGCTTCACGGTCCGCATCGAGTGCGAATAGGCCCGGTCCGCCGCTTCCACGCCCCGCCCGTCTTCCCTCGGCGGGGG
GCAGTCACTACCTTCCCCTT

Downstream 100 bases:

>100_bases
GCCGCAGGGGCCAGCAACGGACGCGGACCGGCGGAATGCGTTAGGATGAGGCGTCCCCGTTGCGGGGACATCGCGAGGGA
GACGGAACGTGCCGCCATTT

Product: periplasmic serine protease

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSDDLIAAAKRRFTDLLPQSWRRDLTLVPVVRLSGAIGMNSPFRQSLTLAATARLLDRAFAVKRAPAVALVINSPGGSPV
QSNLIFKRIRALAEEKNKRVFAFVEDVAASGGYMLACAADEIYADPSSIVGSIGVVSAGFGFNDMLSRIGVERRVHTAGT
RKVMLDPFQPERAEDVDRLLAIQREVHASFRDLVRSRRGALLKGEEDDLFSGEFWVGAQALPMGLIDGLGDLRSVLRERF
GTDVRTPLIAPSGNWFTRRANGIGAQIGLDGGIGAGFAQGLADVAEERALWARYGL

Sequences:

>Translated_296_residues
MSDDLIAAAKRRFTDLLPQSWRRDLTLVPVVRLSGAIGMNSPFRQSLTLAATARLLDRAFAVKRAPAVALVINSPGGSPV
QSNLIFKRIRALAEEKNKRVFAFVEDVAASGGYMLACAADEIYADPSSIVGSIGVVSAGFGFNDMLSRIGVERRVHTAGT
RKVMLDPFQPERAEDVDRLLAIQREVHASFRDLVRSRRGALLKGEEDDLFSGEFWVGAQALPMGLIDGLGDLRSVLRERF
GTDVRTPLIAPSGNWFTRRANGIGAQIGLDGGIGAGFAQGLADVAEERALWARYGL
>Mature_295_residues
SDDLIAAAKRRFTDLLPQSWRRDLTLVPVVRLSGAIGMNSPFRQSLTLAATARLLDRAFAVKRAPAVALVINSPGGSPVQ
SNLIFKRIRALAEEKNKRVFAFVEDVAASGGYMLACAADEIYADPSSIVGSIGVVSAGFGFNDMLSRIGVERRVHTAGTR
KVMLDPFQPERAEDVDRLLAIQREVHASFRDLVRSRRGALLKGEEDDLFSGEFWVGAQALPMGLIDGLGDLRSVLRERFG
TDVRTPLIAPSGNWFTRRANGIGAQIGLDGGIGAGFAQGLADVAEERALWARYGL

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=170, Percent_Identity=35.8823529411765, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788064, Length=171, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 32038; Mature: 31907

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDLIAAAKRRFTDLLPQSWRRDLTLVPVVRLSGAIGMNSPFRQSLTLAATARLLDRAF
CCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVKRAPAVALVINSPGGSPVQSNLIFKRIRALAEEKNKRVFAFVEDVAASGGYMLACAAD
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCEEEEEECH
EIYADPSSIVGSIGVVSAGFGFNDMLSRIGVERRVHTAGTRKVMLDPFQPERAEDVDRLL
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
AIQREVHASFRDLVRSRRGALLKGEEDDLFSGEFWVGAQALPMGLIDGLGDLRSVLRERF
HHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEECCHHHHHHHHHCHHHHHHHHHHHH
GTDVRTPLIAPSGNWFTRRANGIGAQIGLDGGIGAGFAQGLADVAEERALWARYGL
CCCCCCCEECCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDDLIAAAKRRFTDLLPQSWRRDLTLVPVVRLSGAIGMNSPFRQSLTLAATARLLDRAF
CCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVKRAPAVALVINSPGGSPVQSNLIFKRIRALAEEKNKRVFAFVEDVAASGGYMLACAAD
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCEEEEEECH
EIYADPSSIVGSIGVVSAGFGFNDMLSRIGVERRVHTAGTRKVMLDPFQPERAEDVDRLL
HHHCCHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
AIQREVHASFRDLVRSRRGALLKGEEDDLFSGEFWVGAQALPMGLIDGLGDLRSVLRERF
HHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEECCHHHHHHHHHCHHHHHHHHHHHH
GTDVRTPLIAPSGNWFTRRANGIGAQIGLDGGIGAGFAQGLADVAEERALWARYGL
CCCCCCCEECCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA