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The map label for this gene is appC [H]

Identifier: 158422434

GI number: 158422434

Start: 914131

End: 915048

Strand: Reverse

Name: appC [H]

Synonym: AZC_0810

Alternate gene names: 158422434

Gene position: 915048-914131 (Counterclockwise)

Preceding gene: 158422435

Following gene: 158422433

Centisome position: 17.04

GC content: 68.41

Gene sequence:

>918_bases
ATGACTGACCTTGCCCCTTCCGCCACCGAGGCCTCGCGCCTTGATGCGGCGCCGCCGCGCCGCTCCCCAAGCATGGCGCT
GCTGCGCCGGAGCCTGCGCCATGGCGGGCTGATGGCCGGCGCCGTCATCCTTTTCCTCATCATCGCCCTCGCCCTGCTGG
CACCGCTGATCGCCCCGCACGATCCCTATGCGCAGGATCTCTCCCGCCGCATGATGCCACCGGTCTGGCAGGCCAAGGGC
ACGTGGGAGCACATCCTCGGCACCGACAAGCTGGGCCGCGATTATCTGAGCCGCCTGCTGTTCGGCGCGCGCATCTCGCT
GCTCATCGGCGCGGTGACGGTGCTCATCTCCGGCACCATCGGCACGCTGCTCGGCGTCTGCGCCGGCTATTTCGGCGGCC
GGGTGGATGCGGTGTTGAGCTACATCGTCACCACGCGCCTTGCCCTGCCCGTGGTGCTGGTGGCGCTGGCCTCCGCCGCG
CTCGTCGGTTCCTCGTTGCAGGGCGTCATCATCGTACTGGGCCTGCTGTTGTGGGACCGCTTCGCGGTCGTGACACGCTC
GGCCACGCAGCAGATCGCCGGCAGCGACTATATCGGCGCCGCCAAGGCCATCGGCTGCTCGACGCCGCGCATCATCCTCT
CGGAAATCCTGCCCAACATCCTCAACCCGCTGATCGTCGTGGCGACGCTGGAAATGGCCCACGCCATCCTGCTGGAAGCC
GCGCTCTCCTTCCTCGGCCTCGGCGTGCAGCCGCCGCTCCCCTCGTGGGGCCTGATGATCGCCGAGGGCAAGCAGTACAT
GTTCTTCAGCCCCTGGGTCATCGCCGTGCCGGCCACCGCTCTGGTGTTCCTGGTCCTCGCCATCAACCTCCTCGGCGACG
GCCTGCGTGACGTCACCGCGCCCGAGAACAGGAACTGA

Upstream 100 bases:

>100_bases
TGGTGCAGGCGGTCGTGCTCATCCTCGCCGCCATCTACATCACGCTCACCTTCCTCGCGGATGTGGTCAACGCCTTGCTC
GATCCCCGGATGCGCGTCGC

Downstream 100 bases:

>100_bases
GCCATGGCTTTGCTGGAGGTGAAAGACCTCGTCATCGACATTCCGACCGAGGCCGGCGTGCTGCACGCGGTGAGCGGCAT
CTCCTTCTCGCTGGAGCGGG

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTDLAPSATEASRLDAAPPRRSPSMALLRRSLRHGGLMAGAVILFLIIALALLAPLIAPHDPYAQDLSRRMMPPVWQAKG
TWEHILGTDKLGRDYLSRLLFGARISLLIGAVTVLISGTIGTLLGVCAGYFGGRVDAVLSYIVTTRLALPVVLVALASAA
LVGSSLQGVIIVLGLLLWDRFAVVTRSATQQIAGSDYIGAAKAIGCSTPRIILSEILPNILNPLIVVATLEMAHAILLEA
ALSFLGLGVQPPLPSWGLMIAEGKQYMFFSPWVIAVPATALVFLVLAINLLGDGLRDVTAPENRN

Sequences:

>Translated_305_residues
MTDLAPSATEASRLDAAPPRRSPSMALLRRSLRHGGLMAGAVILFLIIALALLAPLIAPHDPYAQDLSRRMMPPVWQAKG
TWEHILGTDKLGRDYLSRLLFGARISLLIGAVTVLISGTIGTLLGVCAGYFGGRVDAVLSYIVTTRLALPVVLVALASAA
LVGSSLQGVIIVLGLLLWDRFAVVTRSATQQIAGSDYIGAAKAIGCSTPRIILSEILPNILNPLIVVATLEMAHAILLEA
ALSFLGLGVQPPLPSWGLMIAEGKQYMFFSPWVIAVPATALVFLVLAINLLGDGLRDVTAPENRN
>Mature_304_residues
TDLAPSATEASRLDAAPPRRSPSMALLRRSLRHGGLMAGAVILFLIIALALLAPLIAPHDPYAQDLSRRMMPPVWQAKGT
WEHILGTDKLGRDYLSRLLFGARISLLIGAVTVLISGTIGTLLGVCAGYFGGRVDAVLSYIVTTRLALPVVLVALASAAL
VGSSLQGVIIVLGLLLWDRFAVVTRSATQQIAGSDYIGAAKAIGCSTPRIILSEILPNILNPLIVVATLEMAHAILLEAA
LSFLGLGVQPPLPSWGLMIAEGKQYMFFSPWVIAVPATALVFLVLAINLLGDGLRDVTAPENRN

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=283, Percent_Identity=38.5159010600707, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787760, Length=262, Percent_Identity=38.1679389312977, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1789964, Length=296, Percent_Identity=39.1891891891892, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=33.695652173913, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787549, Length=248, Percent_Identity=37.9032258064516, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=34.8360655737705, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788505, Length=221, Percent_Identity=28.9592760180996, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32281; Mature: 32150

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLAPSATEASRLDAAPPRRSPSMALLRRSLRHGGLMAGAVILFLIIALALLAPLIAPH
CCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
DPYAQDLSRRMMPPVWQAKGTWEHILGTDKLGRDYLSRLLFGARISLLIGAVTVLISGTI
CCHHHHHHHHCCCCCHHCCCCHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLLGVCAGYFGGRVDAVLSYIVTTRLALPVVLVALASAALVGSSLQGVIIVLGLLLWDR
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FAVVTRSATQQIAGSDYIGAAKAIGCSTPRIILSEILPNILNPLIVVATLEMAHAILLEA
HHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSFLGLGVQPPLPSWGLMIAEGKQYMFFSPWVIAVPATALVFLVLAINLLGDGLRDVTA
HHHHHCCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
PENRN
CCCCC
>Mature Secondary Structure 
TDLAPSATEASRLDAAPPRRSPSMALLRRSLRHGGLMAGAVILFLIIALALLAPLIAPH
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
DPYAQDLSRRMMPPVWQAKGTWEHILGTDKLGRDYLSRLLFGARISLLIGAVTVLISGTI
CCHHHHHHHHCCCCCHHCCCCHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLLGVCAGYFGGRVDAVLSYIVTTRLALPVVLVALASAALVGSSLQGVIIVLGLLLWDR
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FAVVTRSATQQIAGSDYIGAAKAIGCSTPRIILSEILPNILNPLIVVATLEMAHAILLEA
HHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSFLGLGVQPPLPSWGLMIAEGKQYMFFSPWVIAVPATALVFLVLAINLLGDGLRDVTA
HHHHHCCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
PENRN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]