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The map label for this gene is gntR [H]

Identifier: 158422354

GI number: 158422354

Start: 821661

End: 823163

Strand: Direct

Name: gntR [H]

Synonym: AZC_0730

Alternate gene names: 158422354

Gene position: 821661-823163 (Clockwise)

Preceding gene: 158422352

Following gene: 158422355

Centisome position: 15.3

GC content: 67.07

Gene sequence:

>1503_bases
TTGGGCGGCGGTGGCCGCGATAAGCATCAGGCTGAACTGTACATAGGCGCTCACGCCGCGCCGGAGCGGGAGGCTCCCGA
CATGCTTTCGATCACGCTCGATGCCGGTGGCAAGGTGCCGCTCGTCTCGCAGATCGTGGCGGCGGTGGCGGAGCAGATCG
CCGAGGGCGTGTTGGCCCCCGGAGCGCGCCTGCCTTCGGTGCGGCAACTGGCCGCCGAATGCAGCGTCAGCACGCTCACC
GTCTCCAATGCCTATAACCGGCTCGTGGCGGAGGGCTATCTGGAGGCGCGCCGGGCCAGCGGTTATTACGTCGCCATGCG
GAAGGCGGCGCGGGAGCCGCAGCGGCGGCAGGCGCAGAATTCGGTCCCCATCGATGCCCTCTGGCTGCTCCAGCGCGTCT
ATGAGGACGACCCCAACCTGCTGAAGGTGGGCTCGGGATGGCTCCCGGAAAGCCATCTCTTCACCGACGGGCTGCGCCAT
TCCCTGTCCGCGCTCGCCAAGAAGCCGGCTTCGGCCGTCTCGCGCTACGGCAATCCCCATGGCTATGAGCCGCTGCGGCG
GGCCATCCAGATGCTGCTCGCCCAGCGGGCCATCGACTGCGAGCCGGACAACATCATCCTCACCCATGGCGCCTCGCAGG
CCCTCGACATCGCCGCGCGCGGGCTGCTCCAGGCGGGCGACACCGCCTTCGTGGACGATCCCGGCTATTGCAACCTCTTC
CCGACGCTACGGGCGCTTGGCGTGCGGATCATCGGCATTCCCCGCACGCCGCAGGGGCCGGACGTGGAGGCGCTGGAGGC
TCTGGCGGAACGCTATCGCCCCCGCGTCTTCTTTACCAACACCATCCTGCACAATCCCACCGGCACCGGTTGCCCGCCGG
CGGTCATCTACCGCGTGCTGCGAGTGGCGGAGGACTTCGACTTCCACATCGTGGAGGACGACATCTTCGCCGGCATGGCC
CCGGACCAGATGCCCAGCATCGCCAGCCTCGACCAGTTCCGCCGGGTGCTCTATGCCGGCTCCTTCTCCAAGACCATCTC
GCCGAGTCTCCGCGTCGGCTATCTGGTGGTGGGGCGGGATCTCGTGGAACGGATGCTCTATCTGAAGCTCGCCGGCGGCC
TCACCAGTTCGGAAATCAGCGAGCAGGTGGTGCATTCCATCCTGGTGGACGGCCACCACCGGCTGCATCTGGCACGCCTG
CGCGACAAGCTTGCGGTGGCGCAGAAGACGGTGTGCGCCGGCCTTGAGAATGCAGGCCTCTCCATCTTTCATCGGCCGAA
CGGCGGCATGTTCGTATGGGCCGCCTTGCCCGGCGCACCGGACATGGAGGCGGTGGCCCATCAGGCCATGGAAGAAGGCA
TCATGCTCGCACCGGGCGCCCTGTTTCGCGCCGACCAGAAGGCCACCCCCTTCATGCGCTTCAATGTGACCCACGCCGAC
CATCCAAGGCTCTATCGCTTCCTCGAACGGGTTTGCGAGCGAGCGCTGCGAGAGAAGGCTTGA

Upstream 100 bases:

>100_bases
CGCCTGCTGAAGCTGTTATGGTCGCCTGACCGATACAGTGAAGGGGCGGCCAGCGTCGTCTGGCCTTTGTCCGTGAACCG
TTTGTCAGCCTGCCTGCGCC

Downstream 100 bases:

>100_bases
TCCGCAGACCGATATGGTTCACTCGGGTGGTATACCGTGTGTAAACCACCCTCTCCCGCGCTTCCAGACGGAGTTTTCCC
ATGCGCCTCACCGCCGATGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MGGGGRDKHQAELYIGAHAAPEREAPDMLSITLDAGGKVPLVSQIVAAVAEQIAEGVLAPGARLPSVRQLAAECSVSTLT
VSNAYNRLVAEGYLEARRASGYYVAMRKAAREPQRRQAQNSVPIDALWLLQRVYEDDPNLLKVGSGWLPESHLFTDGLRH
SLSALAKKPASAVSRYGNPHGYEPLRRAIQMLLAQRAIDCEPDNIILTHGASQALDIAARGLLQAGDTAFVDDPGYCNLF
PTLRALGVRIIGIPRTPQGPDVEALEALAERYRPRVFFTNTILHNPTGTGCPPAVIYRVLRVAEDFDFHIVEDDIFAGMA
PDQMPSIASLDQFRRVLYAGSFSKTISPSLRVGYLVVGRDLVERMLYLKLAGGLTSSEISEQVVHSILVDGHHRLHLARL
RDKLAVAQKTVCAGLENAGLSIFHRPNGGMFVWAALPGAPDMEAVAHQAMEEGIMLAPGALFRADQKATPFMRFNVTHAD
HPRLYRFLERVCERALREKA

Sequences:

>Translated_500_residues
MGGGGRDKHQAELYIGAHAAPEREAPDMLSITLDAGGKVPLVSQIVAAVAEQIAEGVLAPGARLPSVRQLAAECSVSTLT
VSNAYNRLVAEGYLEARRASGYYVAMRKAAREPQRRQAQNSVPIDALWLLQRVYEDDPNLLKVGSGWLPESHLFTDGLRH
SLSALAKKPASAVSRYGNPHGYEPLRRAIQMLLAQRAIDCEPDNIILTHGASQALDIAARGLLQAGDTAFVDDPGYCNLF
PTLRALGVRIIGIPRTPQGPDVEALEALAERYRPRVFFTNTILHNPTGTGCPPAVIYRVLRVAEDFDFHIVEDDIFAGMA
PDQMPSIASLDQFRRVLYAGSFSKTISPSLRVGYLVVGRDLVERMLYLKLAGGLTSSEISEQVVHSILVDGHHRLHLARL
RDKLAVAQKTVCAGLENAGLSIFHRPNGGMFVWAALPGAPDMEAVAHQAMEEGIMLAPGALFRADQKATPFMRFNVTHAD
HPRLYRFLERVCERALREKA
>Mature_499_residues
GGGGRDKHQAELYIGAHAAPEREAPDMLSITLDAGGKVPLVSQIVAAVAEQIAEGVLAPGARLPSVRQLAAECSVSTLTV
SNAYNRLVAEGYLEARRASGYYVAMRKAAREPQRRQAQNSVPIDALWLLQRVYEDDPNLLKVGSGWLPESHLFTDGLRHS
LSALAKKPASAVSRYGNPHGYEPLRRAIQMLLAQRAIDCEPDNIILTHGASQALDIAARGLLQAGDTAFVDDPGYCNLFP
TLRALGVRIIGIPRTPQGPDVEALEALAERYRPRVFFTNTILHNPTGTGCPPAVIYRVLRVAEDFDFHIVEDDIFAGMAP
DQMPSIASLDQFRRVLYAGSFSKTISPSLRVGYLVVGRDLVERMLYLKLAGGLTSSEISEQVVHSILVDGHHRLHLARLR
DKLAVAQKTVCAGLENAGLSIFHRPNGGMFVWAALPGAPDMEAVAHQAMEEGIMLAPGALFRADQKATPFMRFNVTHADH
PRLYRFLERVCERALREKA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=316, Percent_Identity=25.3164556962025, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI33469970, Length=316, Percent_Identity=25.3164556962025, Blast_Score=116, Evalue=6e-26,
Organism=Escherichia coli, GI1787710, Length=447, Percent_Identity=29.7539149888143, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1790797, Length=439, Percent_Identity=30.2961275626424, Blast_Score=163, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21356535, Length=411, Percent_Identity=24.5742092457421, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54623; Mature: 54492

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGGGRDKHQAELYIGAHAAPEREAPDMLSITLDAGGKVPLVSQIVAAVAEQIAEGVLAP
CCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
GARLPSVRQLAAECSVSTLTVSNAYNRLVAEGYLEARRASGYYVAMRKAAREPQRRQAQN
CCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHC
SVPIDALWLLQRVYEDDPNLLKVGSGWLPESHLFTDGLRHSLSALAKKPASAVSRYGNPH
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
GYEPLRRAIQMLLAQRAIDCEPDNIILTHGASQALDIAARGLLQAGDTAFVDDPGYCNLF
CHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCHH
PTLRALGVRIIGIPRTPQGPDVEALEALAERYRPRVFFTNTILHNPTGTGCPPAVIYRVL
HHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECEEECCCCCCCCHHHHHHHH
RVAEDFDFHIVEDDIFAGMAPDQMPSIASLDQFRRVLYAGSFSKTISPSLRVGYLVVGRD
HHHCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCCEEEHEEECHH
LVERMLYLKLAGGLTSSEISEQVVHSILVDGHHRLHLARLRDKLAVAQKTVCAGLENAGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
SIFHRPNGGMFVWAALPGAPDMEAVAHQAMEEGIMLAPGALFRADQKATPFMRFNVTHAD
EEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCEEECCCHHHCCCCCCCCEEEEECCCCC
HPRLYRFLERVCERALREKA
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GGGGRDKHQAELYIGAHAAPEREAPDMLSITLDAGGKVPLVSQIVAAVAEQIAEGVLAP
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
GARLPSVRQLAAECSVSTLTVSNAYNRLVAEGYLEARRASGYYVAMRKAAREPQRRQAQN
CCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHC
SVPIDALWLLQRVYEDDPNLLKVGSGWLPESHLFTDGLRHSLSALAKKPASAVSRYGNPH
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
GYEPLRRAIQMLLAQRAIDCEPDNIILTHGASQALDIAARGLLQAGDTAFVDDPGYCNLF
CHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCHH
PTLRALGVRIIGIPRTPQGPDVEALEALAERYRPRVFFTNTILHNPTGTGCPPAVIYRVL
HHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECEEECCCCCCCCHHHHHHHH
RVAEDFDFHIVEDDIFAGMAPDQMPSIASLDQFRRVLYAGSFSKTISPSLRVGYLVVGRD
HHHCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCCCEEEHEEECHH
LVERMLYLKLAGGLTSSEISEQVVHSILVDGHHRLHLARLRDKLAVAQKTVCAGLENAGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
SIFHRPNGGMFVWAALPGAPDMEAVAHQAMEEGIMLAPGALFRADQKATPFMRFNVTHAD
EEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCEEECCCHHHCCCCCCCCEEEEECCCCC
HPRLYRFLERVCERALREKA
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]