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The map label for this gene is tsr [C]

Identifier: 158422349

GI number: 158422349

Start: 812940

End: 815033

Strand: Reverse

Name: tsr [C]

Synonym: AZC_0725

Alternate gene names: 158422349

Gene position: 815033-812940 (Counterclockwise)

Preceding gene: 158422350

Following gene: 158422348

Centisome position: 15.18

GC content: 68.34

Gene sequence:

>2094_bases
ATGAAGTTGACCATCAAGACGACCCTGATCGGTCTGTTTTCCGTCATCAGCGCAACCATTGCCGCCCTGTGCATCGGCTC
GCTGTCTTCGGCCCTGAAGAGCAACAGCGACGCGGCGACCGCGCTCCAGTATGTGACCGCCGCCCACGATCTGTTTTCCG
CCTACAGCAACCTGCGTCTGGAACGGGCCGACGGCGGCTTTGCCCTGCCGGCGACACCGGACAAGATGGGCCCGCTCATC
GAGACCATGAATGCCCGCCGCAAGACCGTGAACACGGGCATGGACGGGACGGTCGCAGCCCTCCAGAAGCTCGATCTGCC
GCAGGCGAAGGCGCTGCTCCGGCAGGTTTCCGGCGACTACCAGACCATCCAGAACCTGCGCTCGGACCTCGACAGCGCGC
TCCAGCGGCCCAAGGAGAGCCGCGATCCCGCGCTGCTGCCGCGCTACATGAAGGAGATGGCGGACGTCATCAAGCGCATG
GAAGCCACCATGGAGGCGGTGGACACCGAGATCCGCATGGTGGAGGCCGGCCTCCTGCGCTTCATCACGCTGCGCAGTTC
GGCCGGCGCCCTGCGGACCGCCGCCGGTGATGCGGCGCTGCTCATCAGCGTCGCGCTGCGCGAGGGCCGCGCCTTCACGG
CGGCGGAAACGGCGACGATCACGGGCGCGAATGCCAAGATCGACCTTGCCTGGTCGCAGACCCGCAGCTTCGGCAATGCC
GTGGACATGCCCGCCGGTATCCGAAGCGCCGTCGCCACGGCCGAGCGCACCTTCTTCGTGGATCCGGTGAAGGCCATGCG
GGACGACCTCGCCAAGAGCCTTGCCACCGCCCCGGTGAAGACGACGGGCATCGACGACTGGCGCAACAAGATCATTCCCG
CGCTCGACGACCTCACCAACATCAGCCTCGCCGCCATGGTCAGTCTCTCGGAAGAGGCCGAAGCCATCGCCGACGGGGCT
CGCAAGACCCTGTTCTTCTATGCCGGCCTGATCGTGTTCGCGCTGGCCATGGTGGTGGCCGGTCTCCTGGTGGTCATCAC
CCGTGTCACCCGGCCGATCAGCGGCCTCACCTCGACCATGCAGGCCCTCGCGGGCGGCAATCTCGATGTGGCGGTACCGA
ATACCGAGCGGCACGATGAGGTGGGCGCCATGGCCAAGGCCCTTCTAGTCTTCAAGGAGGAGATGGCCCGGAATGCGGCT
CTGGAAGCCGAAGCCGAGGCGGCCCGCCTCAAGGCCGAGGCGGAGCGCCGCGAAGGCATGATGCGCCTCGCTGCCGAGTT
CGAGAGCGCGGTGGGCGGCATCATCGGCAGCGTGGCCTCCGCCTCCACCCAGCTCCACGGCACTGCCCGCACGATGGCGG
AAGCCGCACGCCGCACCTCGGAGAAGTCCACGGCGGTGGCAGCGGCCGCCGAGGAAGCCTCCACCAACGTGGTCATGGTC
GCCTCCTCCGCCGAGGAACTGGGTTCCTCCGTGGACGAGATCGGCCGGCAGGTGCAGCAGTCGGCCGAGATGTCCAACGT
CGCCGTCGCCGAGGCGCAGAAGACCGGCACGGTCATCCAGGATCTGGCGCAGGCCGCGTCCCGCATCGGCGACGTGGTGG
GGCTCATCTCCTCCATCGCCGAGCAGACCAACCTCCTCGCCCTCAACGCCACCATCGAGGCGGCGCGAGCCGGCGACGCC
GGCAAGGGCTTCGCGGTGGTCGCCTCCGAGGTGAAGGCGCTGGCCACCCAGACCGCCAAGGCGACGGAAGAGATCGAGAG
CCAGATCGGCGCCATCCAGGCCACCACCAAGCAGGCGGTGCAGGTCATCGAGGGCGTCGGCTCGCAGATCCGCAAGATGA
GCGACGTGGCCACCAGCATCTCCGCCGCCGTCGAGGAGCAGGGCGTCGCCACCCGCGAAATCGTCCGCAACGTCGACCAG
GCCGCCACCGGCACCAACAGCGTGACCGCCCACATCTCGGAAGTGGCCCAAACCGCCGACGAGACCGGTTCCGCCGCCGG
GCAGGTGCTCACCGCCGCCGCCGCCCTCACCGATCAGGCCAAGCGCCTCGAAGCGGAAATGCAGCGCTTCCTCGGCACAG
TCCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
AAGCGACATCAAGATCGCCCGATAAAATTCAGCCGGTGCTTTGCCGCGCTGAGACGCCTGACGGCCTTCAAGGCCGGCCA
CGCCAAGGGAAGACGCGTCC

Downstream 100 bases:

>100_bases
GGCGGGAAGGAGAGACGCCGGGCGTCCGACGCCCGGCGGTTTGCCGGCAAGACACCACAACCAAAGGTACCCACAAGGTT
CGGACAAGGCTCACAGGATA

Product: histidine kinase

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MKLTIKTTLIGLFSVISATIAALCIGSLSSALKSNSDAATALQYVTAAHDLFSAYSNLRLERADGGFALPATPDKMGPLI
ETMNARRKTVNTGMDGTVAALQKLDLPQAKALLRQVSGDYQTIQNLRSDLDSALQRPKESRDPALLPRYMKEMADVIKRM
EATMEAVDTEIRMVEAGLLRFITLRSSAGALRTAAGDAALLISVALREGRAFTAAETATITGANAKIDLAWSQTRSFGNA
VDMPAGIRSAVATAERTFFVDPVKAMRDDLAKSLATAPVKTTGIDDWRNKIIPALDDLTNISLAAMVSLSEEAEAIADGA
RKTLFFYAGLIVFALAMVVAGLLVVITRVTRPISGLTSTMQALAGGNLDVAVPNTERHDEVGAMAKALLVFKEEMARNAA
LEAEAEAARLKAEAERREGMMRLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMV
ASSAEELGSSVDEIGRQVQQSAEMSNVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIAEQTNLLALNATIEAARAGDA
GKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAVQVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQ
AATGTNSVTAHISEVAQTADETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRAA

Sequences:

>Translated_697_residues
MKLTIKTTLIGLFSVISATIAALCIGSLSSALKSNSDAATALQYVTAAHDLFSAYSNLRLERADGGFALPATPDKMGPLI
ETMNARRKTVNTGMDGTVAALQKLDLPQAKALLRQVSGDYQTIQNLRSDLDSALQRPKESRDPALLPRYMKEMADVIKRM
EATMEAVDTEIRMVEAGLLRFITLRSSAGALRTAAGDAALLISVALREGRAFTAAETATITGANAKIDLAWSQTRSFGNA
VDMPAGIRSAVATAERTFFVDPVKAMRDDLAKSLATAPVKTTGIDDWRNKIIPALDDLTNISLAAMVSLSEEAEAIADGA
RKTLFFYAGLIVFALAMVVAGLLVVITRVTRPISGLTSTMQALAGGNLDVAVPNTERHDEVGAMAKALLVFKEEMARNAA
LEAEAEAARLKAEAERREGMMRLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMV
ASSAEELGSSVDEIGRQVQQSAEMSNVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIAEQTNLLALNATIEAARAGDA
GKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAVQVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQ
AATGTNSVTAHISEVAQTADETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRAA
>Mature_697_residues
MKLTIKTTLIGLFSVISATIAALCIGSLSSALKSNSDAATALQYVTAAHDLFSAYSNLRLERADGGFALPATPDKMGPLI
ETMNARRKTVNTGMDGTVAALQKLDLPQAKALLRQVSGDYQTIQNLRSDLDSALQRPKESRDPALLPRYMKEMADVIKRM
EATMEAVDTEIRMVEAGLLRFITLRSSAGALRTAAGDAALLISVALREGRAFTAAETATITGANAKIDLAWSQTRSFGNA
VDMPAGIRSAVATAERTFFVDPVKAMRDDLAKSLATAPVKTTGIDDWRNKIIPALDDLTNISLAAMVSLSEEAEAIADGA
RKTLFFYAGLIVFALAMVVAGLLVVITRVTRPISGLTSTMQALAGGNLDVAVPNTERHDEVGAMAKALLVFKEEMARNAA
LEAEAEAARLKAEAERREGMMRLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMV
ASSAEELGSSVDEIGRQVQQSAEMSNVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIAEQTNLLALNATIEAARAGDA
GKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAVQVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQ
AATGTNSVTAHISEVAQTADETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=25.4601226993865, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787690, Length=414, Percent_Identity=24.8792270531401, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788194, Length=279, Percent_Identity=28.673835125448, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789453, Length=146, Percent_Identity=40.4109589041096, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788195, Length=187, Percent_Identity=31.5508021390374, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72829; Mature: 72829

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTIKTTLIGLFSVISATIAALCIGSLSSALKSNSDAATALQYVTAAHDLFSAYSNLRL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEE
ERADGGFALPATPDKMGPLIETMNARRKTVNTGMDGTVAALQKLDLPQAKALLRQVSGDY
EECCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCH
QTIQNLRSDLDSALQRPKESRDPALLPRYMKEMADVIKRMEATMEAVDTEIRMVEAGLLR
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITLRSSAGALRTAAGDAALLISVALREGRAFTAAETATITGANAKIDLAWSQTRSFGNA
HHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEHHHHHCCCCC
VDMPAGIRSAVATAERTFFVDPVKAMRDDLAKSLATAPVKTTGIDDWRNKIIPALDDLTN
CCCCHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHH
ISLAAMVSLSEEAEAIADGARKTLFFYAGLIVFALAMVVAGLLVVITRVTRPISGLTSTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALAGGNLDVAVPNTERHDEVGAMAKALLVFKEEMARNAALEAEAEAARLKAEAERREGM
HHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
ASSAEELGSSVDEIGRQVQQSAEMSNVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIA
ECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAV
HHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQAATGTNSVTAHISEVAQTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLTIKTTLIGLFSVISATIAALCIGSLSSALKSNSDAATALQYVTAAHDLFSAYSNLRL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEE
ERADGGFALPATPDKMGPLIETMNARRKTVNTGMDGTVAALQKLDLPQAKALLRQVSGDY
EECCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCH
QTIQNLRSDLDSALQRPKESRDPALLPRYMKEMADVIKRMEATMEAVDTEIRMVEAGLLR
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITLRSSAGALRTAAGDAALLISVALREGRAFTAAETATITGANAKIDLAWSQTRSFGNA
HHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEHHHHHCCCCC
VDMPAGIRSAVATAERTFFVDPVKAMRDDLAKSLATAPVKTTGIDDWRNKIIPALDDLTN
CCCCHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHH
ISLAAMVSLSEEAEAIADGARKTLFFYAGLIVFALAMVVAGLLVVITRVTRPISGLTSTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALAGGNLDVAVPNTERHDEVGAMAKALLVFKEEMARNAALEAEAEAARLKAEAERREGM
HHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
ASSAEELGSSVDEIGRQVQQSAEMSNVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIA
ECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAV
HHHCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQAATGTNSVTAHISEVAQTAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]