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The map label for this gene is trxA [C]

Identifier: 158422339

GI number: 158422339

Start: 800514

End: 800834

Strand: Direct

Name: trxA [C]

Synonym: AZC_0715

Alternate gene names: 158422339

Gene position: 800514-800834 (Clockwise)

Preceding gene: 158422338

Following gene: 158422341

Centisome position: 14.91

GC content: 65.11

Gene sequence:

>321_bases
ATGGCCGTCGAAAAAGTATCCGATCAGAGCTTCGATGCCGACGTGCTCCAGTCCTCCACCCCGGTGGTCGTGGACTTCTG
GGCCGAGTGGTGCGGCCCCTGCCGCATGGTCGCCCCGGTGCTCGACGAGCTCTCCGGCGAGCTTGGCGACAAGGTGAAGA
TCGTGAAGCTGAACGTGGACGAGAACCCGGTGACGGCGTCCAAGTACGGCATCATGTCCATCCCCACCCTGCTGCTGTTC
AAGGATGGCAAGATCGCCTCCCGTCAGGTGGGCGCCGCCGCCAAGGCCAAGCTCGCGAGCTGGATCGGCTCCGCCGCCTG
A

Upstream 100 bases:

>100_bases
CACGCCGCCGTGACGCGCCTTGACGGAGAGGGGAGGGGCTTCTTACGTTGAGCCCAAGATCCAGTGGATCGCCTGTGAAA
TCCCTACGAGGTATACGCCC

Downstream 100 bases:

>100_bases
GCTGCGGGCCGGTCGTTCGGGAATGCAAAAGGCGGGTCCTTCGGGGCCCGCCTTTTTGTTTGTCCATTTGCCTTGGGCCG
CCGCAGCGACTCAGGGGGCG

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MAVEKVSDQSFDADVLQSSTPVVVDFWAEWCGPCRMVAPVLDELSGELGDKVKIVKLNVDENPVTASKYGIMSIPTLLLF
KDGKIASRQVGAAAKAKLASWIGSAA

Sequences:

>Translated_106_residues
MAVEKVSDQSFDADVLQSSTPVVVDFWAEWCGPCRMVAPVLDELSGELGDKVKIVKLNVDENPVTASKYGIMSIPTLLLF
KDGKIASRQVGAAAKAKLASWIGSAA
>Mature_105_residues
AVEKVSDQSFDADVLQSSTPVVVDFWAEWCGPCRMVAPVLDELSGELGDKVKIVKLNVDENPVTASKYGIMSIPTLLLFK
DGKIASRQVGAAAKAKLASWIGSAA

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=92, Percent_Identity=34.7826086956522, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082331, Length=98, Percent_Identity=54.0816326530612, Blast_Score=127, Evalue=2e-31,
Organism=Escherichia coli, GI1788936, Length=91, Percent_Identity=41.7582417582418, Blast_Score=93, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI212646193, Length=95, Percent_Identity=42.1052631578947, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17509965, Length=89, Percent_Identity=38.2022471910112, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554386, Length=100, Percent_Identity=33, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17510299, Length=75, Percent_Identity=41.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=83, Percent_Identity=45.7831325301205, Blast_Score=74, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321648, Length=92, Percent_Identity=39.1304347826087, Blast_Score=73, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319925, Length=95, Percent_Identity=33.6842105263158, Blast_Score=69, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24639826, Length=92, Percent_Identity=40.2173913043478, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573567, Length=99, Percent_Identity=34.3434343434343, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17648013, Length=78, Percent_Identity=44.8717948717949, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583090, Length=78, Percent_Identity=44.8717948717949, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358065, Length=99, Percent_Identity=34.3434343434343, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24664269, Length=65, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11282; Mature: 11151

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEKVSDQSFDADVLQSSTPVVVDFWAEWCGPCRMVAPVLDELSGELGDKVKIVKLNVD
CCCCCCCCCCCCHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
ENPVTASKYGIMSIPTLLLFKDGKIASRQVGAAAKAKLASWIGSAA
CCCCCCCCCCHHCCCEEEEEECCCCCCHHHCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVEKVSDQSFDADVLQSSTPVVVDFWAEWCGPCRMVAPVLDELSGELGDKVKIVKLNVD
CCCCCCCCCCCHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
ENPVTASKYGIMSIPTLLLFKDGKIASRQVGAAAKAKLASWIGSAA
CCCCCCCCCCHHCCCEEEEEECCCCCCHHHCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7021558 [H]