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The map label for this gene is 158422336

Identifier: 158422336

GI number: 158422336

Start: 792942

End: 793643

Strand: Direct

Name: 158422336

Synonym: AZC_0712

Alternate gene names: NA

Gene position: 792942-793643 (Clockwise)

Preceding gene: 158422335

Following gene: 158422337

Centisome position: 14.77

GC content: 67.81

Gene sequence:

>702_bases
ATGGTGCTTGCGGCAGGCATGGGCACCCGCATGCGCCCCTTGACCGACCACCGGCCGAAGCCGCTGGTGGAGGTGGACGG
CCGCGCGCTGATCGACCATGTGCTCGACCGCCTGGAGGCCTCCGACATTCGCGAGGCGGTGGTGAACGTCCACCACCATG
CCGACCAGCTGGAACAGCATCTGGCGCTGCGCACGGCGCCGCCGCGCATCCACATCTCCGACGAGCGCGGGCAATTGCTG
GAAACCGGCGGCGGCATCCGCAAGGCGCTGCATTTCTTCCATGGCGAGCCTTTCCTCGCCATCAATGCCGACACCATCTG
GATCGAAGGCGTGCAGCCGAACCTGAAGCGGCTCATGGCCCGCTTCGACCCGGCCACCATGGACGCTTTGCTTCTGGTGG
CGGGCGCCGCCACCTCGGTCGGCTATGACGGGGCGGGGGATTTCCTCATGGACCCGAACGGCGTTCTCGACTGGCGCGGC
GAGCGTCTCGTGGCGCCCTTTGTCTATGCGGGCGCCTGCGTGCTCAAGCCGGACCTGTTCGAGGGCACGCCCGAGGGCGG
CTTCTCGCTGACCAAGGTCTTCGCCAAATCCATCGAAGCCCGCCGCCTCTATGGCCTGCGGCTCGAAGGCGTGTGGATGC
ATGTGGGCACGCCCGACGCCATTCCCGCCGCCGAAGAAGCCATCCGCCGCTCGAGCGACTGA

Upstream 100 bases:

>100_bases
CCCGGTGCCTCTCCCATCCCGAACTCGGATCGTTGCGGATGTGGTACGAGGCCGTGTTGCCATCGAGGGAATTCCAGACG
TGACCACGATTTCGCGCGCC

Downstream 100 bases:

>100_bases
GCGGGCCGGCGGTTCCCGCTCGCTGTCTCCAGCCGTGTGCGCTCTCTGAGCCGGCGCCCGGCCAAAGCCCGACCCGCACG
CGGGAGAGGGACTGTGGCGC

Product: nucleotidyltransferase family protein

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVLAAGMGTRMRPLTDHRPKPLVEVDGRALIDHVLDRLEASDIREAVVNVHHHADQLEQHLALRTAPPRIHISDERGQLL
ETGGGIRKALHFFHGEPFLAINADTIWIEGVQPNLKRLMARFDPATMDALLLVAGAATSVGYDGAGDFLMDPNGVLDWRG
ERLVAPFVYAGACVLKPDLFEGTPEGGFSLTKVFAKSIEARRLYGLRLEGVWMHVGTPDAIPAAEEAIRRSSD

Sequences:

>Translated_233_residues
MVLAAGMGTRMRPLTDHRPKPLVEVDGRALIDHVLDRLEASDIREAVVNVHHHADQLEQHLALRTAPPRIHISDERGQLL
ETGGGIRKALHFFHGEPFLAINADTIWIEGVQPNLKRLMARFDPATMDALLLVAGAATSVGYDGAGDFLMDPNGVLDWRG
ERLVAPFVYAGACVLKPDLFEGTPEGGFSLTKVFAKSIEARRLYGLRLEGVWMHVGTPDAIPAAEEAIRRSSD
>Mature_233_residues
MVLAAGMGTRMRPLTDHRPKPLVEVDGRALIDHVLDRLEASDIREAVVNVHHHADQLEQHLALRTAPPRIHISDERGQLL
ETGGGIRKALHFFHGEPFLAINADTIWIEGVQPNLKRLMARFDPATMDALLLVAGAATSVGYDGAGDFLMDPNGVLDWRG
ERLVAPFVYAGACVLKPDLFEGTPEGGFSLTKVFAKSIEARRLYGLRLEGVWMHVGTPDAIPAAEEAIRRSSD

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=225, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355443, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644084, Length=225, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 25523; Mature: 25523

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLAAGMGTRMRPLTDHRPKPLVEVDGRALIDHVLDRLEASDIREAVVNVHHHADQLEQH
CEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LALRTAPPRIHISDERGQLLETGGGIRKALHFFHGEPFLAINADTIWIEGVQPNLKRLMA
HHHCCCCCEEEECCCCCCHHHCCCHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHH
RFDPATMDALLLVAGAATSVGYDGAGDFLMDPNGVLDWRGERLVAPFVYAGACVLKPDLF
HCCCHHHHHHHHHHCCHHHCCCCCCCCCEECCCCCCCCCCCEEECHHHHHCEEEECCHHC
EGTPEGGFSLTKVFAKSIEARRLYGLRLEGVWMHVGTPDAIPAAEEAIRRSSD
CCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MVLAAGMGTRMRPLTDHRPKPLVEVDGRALIDHVLDRLEASDIREAVVNVHHHADQLEQH
CEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LALRTAPPRIHISDERGQLLETGGGIRKALHFFHGEPFLAINADTIWIEGVQPNLKRLMA
HHHCCCCCEEEECCCCCCHHHCCCHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHH
RFDPATMDALLLVAGAATSVGYDGAGDFLMDPNGVLDWRGERLVAPFVYAGACVLKPDLF
HCCCHHHHHHHHHHCCHHHCCCCCCCCCEECCCCCCCCCCCEEECHHHHHCEEEECCHHC
EGTPEGGFSLTKVFAKSIEARRLYGLRLEGVWMHVGTPDAIPAAEEAIRRSSD
CCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA