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The map label for this gene is ycgM [C]

Identifier: 158422297

GI number: 158422297

Start: 744181

End: 744870

Strand: Reverse

Name: ycgM [C]

Synonym: AZC_0673

Alternate gene names: 158422297

Gene position: 744870-744181 (Counterclockwise)

Preceding gene: 158422298

Following gene: 158422294

Centisome position: 13.87

GC content: 65.8

Gene sequence:

>690_bases
ATGGCCAGCTTCGTCATTCCCGCCCCCGTTGTCCCCACCCTGCCGGTGAAGGGCACGGATGCGCTCTTTCCGGTTCACCG
CATCTATTGCGTCGGCCGCAACTTCGCCGACCACGCCATCGAGATGGGTCACGACCCGAACCGCGAGCCGCCCTTCTTCT
TCCAGAAGAACCCCGACAATCTCGTCCCAAGCGGCTCGACCATTCCCTATCCGAAGCTGACCAAGGACGTGCATTACGAG
ATCGAGATGATCGTCGCGCTGAAGACCGGCGGCGACGACATCCCGGTGGAGAAGGCGCTCGACCACGTGTTCGGCTACGG
GGTCGGCATCGACCTCACCCGCCGCGACCTCCAGGCGGAGCAGAAGAAGCTCGGCCGCCCGTGGGATATCGCCAAGGCCT
ATGAGCAGTCCGCCCCGGCAAGCGGCCTCGTGCCTGCGTCCGAGATCGGCCACCCGTCCACCGGCCGCATCTGGCTCTCG
GTGAATGGGGAGACGAAGCAGGACGGCGACCTCAACCAGATGATCTGGAAGGTGCCGGAGATGATCGCCACCCTCTCCAC
CTTCTTCACGCTCCAGCCCGGCGACCTCATTTTCGCCGGCACGCCTGCGGGCGTCGGCCCGGTGAAGGCCGGCGACGTGC
TGAAGGGCGGCGTCGCCAACGTGGGCGAGCTGGAAGTCACCTTCGCCTGA

Upstream 100 bases:

>100_bases
GCCGTGTGATTTCAGGCATTTGAAGCGGCGGATACGGCTTAATCGGCTTCAACTCGACGGCGACTTGCTCTAAGCGGGGG
CGTCTATCGAGGAGCCCTCC

Downstream 100 bases:

>100_bases
GCGCGTTGCAGCAATGAGCAGACGGCCCGCCCCGGTGGCGGGCCGTTTTCATTTGGGCGGCGCGATGAAGCCCACAAAGG
CCTCCGCCGCCCGCGAGCGA

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MASFVIPAPVVPTLPVKGTDALFPVHRIYCVGRNFADHAIEMGHDPNREPPFFFQKNPDNLVPSGSTIPYPKLTKDVHYE
IEMIVALKTGGDDIPVEKALDHVFGYGVGIDLTRRDLQAEQKKLGRPWDIAKAYEQSAPASGLVPASEIGHPSTGRIWLS
VNGETKQDGDLNQMIWKVPEMIATLSTFFTLQPGDLIFAGTPAGVGPVKAGDVLKGGVANVGELEVTFA

Sequences:

>Translated_229_residues
MASFVIPAPVVPTLPVKGTDALFPVHRIYCVGRNFADHAIEMGHDPNREPPFFFQKNPDNLVPSGSTIPYPKLTKDVHYE
IEMIVALKTGGDDIPVEKALDHVFGYGVGIDLTRRDLQAEQKKLGRPWDIAKAYEQSAPASGLVPASEIGHPSTGRIWLS
VNGETKQDGDLNQMIWKVPEMIATLSTFFTLQPGDLIFAGTPAGVGPVKAGDVLKGGVANVGELEVTFA
>Mature_228_residues
ASFVIPAPVVPTLPVKGTDALFPVHRIYCVGRNFADHAIEMGHDPNREPPFFFQKNPDNLVPSGSTIPYPKLTKDVHYEI
EMIVALKTGGDDIPVEKALDHVFGYGVGIDLTRRDLQAEQKKLGRPWDIAKAYEQSAPASGLVPASEIGHPSTGRIWLSV
NGETKQDGDLNQMIWKVPEMIATLSTFFTLQPGDLIFAGTPAGVGPVKAGDVLKGGVANVGELEVTFA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=191, Percent_Identity=41.8848167539267, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=41.2935323383085, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI215422413, Length=191, Percent_Identity=41.8848167539267, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI156231349, Length=226, Percent_Identity=33.1858407079646, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI40786394, Length=226, Percent_Identity=31.858407079646, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1787428, Length=207, Percent_Identity=40.5797101449275, Blast_Score=150, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=35.5670103092784, Blast_Score=148, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=29.9107142857143, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28571789, Length=199, Percent_Identity=32.1608040201005, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=31.1004784688995, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24663695, Length=210, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24715; Mature: 24583

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFVIPAPVVPTLPVKGTDALFPVHRIYCVGRNFADHAIEMGHDPNREPPFFFQKNPDN
CCCEECCCCCCCCCCCCCCCCHHHEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
LVPSGSTIPYPKLTKDVHYEIEMIVALKTGGDDIPVEKALDHVFGYGVGIDLTRRDLQAE
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
QKKLGRPWDIAKAYEQSAPASGLVPASEIGHPSTGRIWLSVNGETKQDGDLNQMIWKVPE
HHHCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
MIATLSTFFTLQPGDLIFAGTPAGVGPVKAGDVLKGGVANVGELEVTFA
HHHHHHHHEEECCCCEEEECCCCCCCCCCCCCHHCCCCCCCCEEEEEEC
>Mature Secondary Structure 
ASFVIPAPVVPTLPVKGTDALFPVHRIYCVGRNFADHAIEMGHDPNREPPFFFQKNPDN
CCEECCCCCCCCCCCCCCCCHHHEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
LVPSGSTIPYPKLTKDVHYEIEMIVALKTGGDDIPVEKALDHVFGYGVGIDLTRRDLQAE
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
QKKLGRPWDIAKAYEQSAPASGLVPASEIGHPSTGRIWLSVNGETKQDGDLNQMIWKVPE
HHHCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
MIATLSTFFTLQPGDLIFAGTPAGVGPVKAGDVLKGGVANVGELEVTFA
HHHHHHHHEEECCCCEEEECCCCCCCCCCCCCHHCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]