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The map label for this gene is mcpE [H]

Identifier: 158422290

GI number: 158422290

Start: 736528

End: 738042

Strand: Direct

Name: mcpE [H]

Synonym: AZC_0666

Alternate gene names: 158422290

Gene position: 736528-738042 (Clockwise)

Preceding gene: 158422289

Following gene: 158422292

Centisome position: 13.72

GC content: 66.93

Gene sequence:

>1515_bases
TTGAGGCTCATCTTACCTGTGGATGACGCACGCGACGCCATCTTCGCGAAAGCGTGGCCGTACAGCATGGGGCGCCCGTT
AAGAAAAAGGTGCGGGCGGATCGGACGCGTCGCCAGCTTTGCGCGTCCTGACCGGGAGGAACTCGCCGCACCACCGCGTG
CCGCGAAACGGGATGGTCCCATGACACAAGAAAGTCTGAGCCAGCGTCTGAATTTCATCGGCATGGACAAGGCCCTTCAG
GCCAGCCTGCGCGAGGCGCGCGATCTGGTGGTCGCCGCGATGCCGAAGATCCTGGATGGCTTCTACGACCACCTGATGAC
CTATCCGGACATGGCCCGGATGTTCCCCACGGCCGCCGTGCGCGCCCACGCCAAGGCGATGCAGATCAAGCACTGGGGCG
TGATCCTCGATGGCCGGTTCGATGCCGCCTATGTGGAATCCGTCACCCGCATCGGCCAGACGCATGCCCGTCTCGGCCTT
GAGCCCCGCTGGTACATCGCGGGCTATGCCCTTCTTCTGAGCGGCCTCGTCGCCGCCATCGAGACCGGCTTCAAGGCCGG
TCGCTTCGACCGCACGGCGCCCGAACGGAAGGCGCGGCTGATCGAGGCGGTCATCACCGCCGCCCTGCTGGATATGGATT
TCGCCATCTCCGTCTATCTCGATGCCGGCATCAAGGCGAAGCGCGAGACCCTCGATCGGGTTGGCGCGGCCTTCCGCAGC
ATCGTGACGACGGTTTCCGACGCCGCCGCGCATCTGGAGACTACGGCGGCCTCGCTGGCCGACACGGCGCAGAGCACGCG
CGCGCTGTCGTCCGCCGTCGCCTCTTCCTCCGAGCAGGCCTCGTCCAACGTGCAGTCGGTGGCGACGGCCTCCGACGAAC
TGGCCGCATCCATCAACGAGATCAGCCGCCAGGTGCGGGAATCGAGCCGCATCGCCGGTGAGGCGGTGGAGCAGGCGCAA
CGCACCGATGAGCGCATCCGCGAGCTCTCGAGCGCCTCGGCGCGCATCGGGGATGTCCTGAAGCTCATCACCGCCATCGC
GGAGCAGACCAATCTCCTCGCGCTCAACGCCACCATCGAGGCCGCGCGCGCGGGCGAGGCGGGGCGCGGCTTCGCGGTGG
TGGCGCAGGAAGTGAAGGCGCTCGCCTCCCAGACGGCCAAGGCCATCGAGGAGATCGGCGGCCAGATCACCTCCATGCAG
TCGGCGACGCAGGATAGCGTGTCGGCGGTGAAGGAGATCGGTCACACCATCGAGCGCCTCGCCGGCATCTCGGAAACCAT
CGCCCATGCGGTGGACAGCCAGACCGAGGCGACGTCCATGATCACCGCCAATGTGGCGCGCGCCGCCGTGGGCACGGAGG
AGGTGGCGACCGCCATCGCCTCGGTGCGGACCCAGGCAGTCAACACCGGATCGGCGTCCGAGGAAGTGCTGGGCTCCGCC
CGGATGCTGAGCTCGGAAAGCCAGAGGCTGAACGAGGAAGTGGAGACCTTCCTGAAGACCATCGATGTGGTCTGA

Upstream 100 bases:

>100_bases
CGGCGCCTGCGGCCATGGCCTCCCGCTGACGGGCACATAAACCCAAGGATAGCGGCCCCGGCGGACAGTCGGGGCCGTTT
TTATTTGCGCAACTGATTAT

Downstream 100 bases:

>100_bases
CGGATAGCCTTCTTTCGGACACGGCTGATCTCTGCTTCGCCGCGTCCCTCCTGACGCTCCGGCCGGCCTTGCGCCGGCCG
TTTGCGTTTCAGGGGTGTAT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MRLILPVDDARDAIFAKAWPYSMGRPLRKRCGRIGRVASFARPDREELAAPPRAAKRDGPMTQESLSQRLNFIGMDKALQ
ASLREARDLVVAAMPKILDGFYDHLMTYPDMARMFPTAAVRAHAKAMQIKHWGVILDGRFDAAYVESVTRIGQTHARLGL
EPRWYIAGYALLLSGLVAAIETGFKAGRFDRTAPERKARLIEAVITAALLDMDFAISVYLDAGIKAKRETLDRVGAAFRS
IVTTVSDAAAHLETTAASLADTAQSTRALSSAVASSSEQASSNVQSVATASDELAASINEISRQVRESSRIAGEAVEQAQ
RTDERIRELSSASARIGDVLKLITAIAEQTNLLALNATIEAARAGEAGRGFAVVAQEVKALASQTAKAIEEIGGQITSMQ
SATQDSVSAVKEIGHTIERLAGISETIAHAVDSQTEATSMITANVARAAVGTEEVATAIASVRTQAVNTGSASEEVLGSA
RMLSSESQRLNEEVETFLKTIDVV

Sequences:

>Translated_504_residues
MRLILPVDDARDAIFAKAWPYSMGRPLRKRCGRIGRVASFARPDREELAAPPRAAKRDGPMTQESLSQRLNFIGMDKALQ
ASLREARDLVVAAMPKILDGFYDHLMTYPDMARMFPTAAVRAHAKAMQIKHWGVILDGRFDAAYVESVTRIGQTHARLGL
EPRWYIAGYALLLSGLVAAIETGFKAGRFDRTAPERKARLIEAVITAALLDMDFAISVYLDAGIKAKRETLDRVGAAFRS
IVTTVSDAAAHLETTAASLADTAQSTRALSSAVASSSEQASSNVQSVATASDELAASINEISRQVRESSRIAGEAVEQAQ
RTDERIRELSSASARIGDVLKLITAIAEQTNLLALNATIEAARAGEAGRGFAVVAQEVKALASQTAKAIEEIGGQITSMQ
SATQDSVSAVKEIGHTIERLAGISETIAHAVDSQTEATSMITANVARAAVGTEEVATAIASVRTQAVNTGSASEEVLGSA
RMLSSESQRLNEEVETFLKTIDVV
>Mature_504_residues
MRLILPVDDARDAIFAKAWPYSMGRPLRKRCGRIGRVASFARPDREELAAPPRAAKRDGPMTQESLSQRLNFIGMDKALQ
ASLREARDLVVAAMPKILDGFYDHLMTYPDMARMFPTAAVRAHAKAMQIKHWGVILDGRFDAAYVESVTRIGQTHARLGL
EPRWYIAGYALLLSGLVAAIETGFKAGRFDRTAPERKARLIEAVITAALLDMDFAISVYLDAGIKAKRETLDRVGAAFRS
IVTTVSDAAAHLETTAASLADTAQSTRALSSAVASSSEQASSNVQSVATASDELAASINEISRQVRESSRIAGEAVEQAQ
RTDERIRELSSASARIGDVLKLITAIAEQTNLLALNATIEAARAGEAGRGFAVVAQEVKALASQTAKAIEEIGGQITSMQ
SATQDSVSAVKEIGHTIERLAGISETIAHAVDSQTEATSMITANVARAAVGTEEVATAIASVRTQAVNTGSASEEVLGSA
RMLSSESQRLNEEVETFLKTIDVV

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=310, Percent_Identity=31.2903225806452, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=270, Percent_Identity=31.4814814814815, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788195, Length=230, Percent_Identity=33.0434782608696, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787690, Length=232, Percent_Identity=32.3275862068966, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789453, Length=227, Percent_Identity=32.15859030837, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR012292
- InterPro:   IPR009050 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 53883; Mature: 53883

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILPVDDARDAIFAKAWPYSMGRPLRKRCGRIGRVASFARPDREELAAPPRAAKRDGP
CEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
MTQESLSQRLNFIGMDKALQASLREARDLVVAAMPKILDGFYDHLMTYPDMARMFPTAAV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RAHAKAMQIKHWGVILDGRFDAAYVESVTRIGQTHARLGLEPRWYIAGYALLLSGLVAAI
HHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ETGFKAGRFDRTAPERKARLIEAVITAALLDMDFAISVYLDAGIKAKRETLDRVGAAFRS
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IVTTVSDAAAHLETTAASLADTAQSTRALSSAVASSSEQASSNVQSVATASDELAASINE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ISRQVRESSRIAGEAVEQAQRTDERIRELSSASARIGDVLKLITAIAEQTNLLALNATIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHH
AARAGEAGRGFAVVAQEVKALASQTAKAIEEIGGQITSMQSATQDSVSAVKEIGHTIERL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGISETIAHAVDSQTEATSMITANVARAAVGTEEVATAIASVRTQAVNTGSASEEVLGSA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RMLSSESQRLNEEVETFLKTIDVV
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLILPVDDARDAIFAKAWPYSMGRPLRKRCGRIGRVASFARPDREELAAPPRAAKRDGP
CEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
MTQESLSQRLNFIGMDKALQASLREARDLVVAAMPKILDGFYDHLMTYPDMARMFPTAAV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RAHAKAMQIKHWGVILDGRFDAAYVESVTRIGQTHARLGLEPRWYIAGYALLLSGLVAAI
HHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ETGFKAGRFDRTAPERKARLIEAVITAALLDMDFAISVYLDAGIKAKRETLDRVGAAFRS
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IVTTVSDAAAHLETTAASLADTAQSTRALSSAVASSSEQASSNVQSVATASDELAASINE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ISRQVRESSRIAGEAVEQAQRTDERIRELSSASARIGDVLKLITAIAEQTNLLALNATIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHH
AARAGEAGRGFAVVAQEVKALASQTAKAIEEIGGQITSMQSATQDSVSAVKEIGHTIERL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGISETIAHAVDSQTEATSMITANVARAAVGTEEVATAIASVRTQAVNTGSASEEVLGSA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RMLSSESQRLNEEVETFLKTIDVV
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]