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The map label for this gene is hypE [H]

Identifier: 158422236

GI number: 158422236

Start: 677681

End: 678748

Strand: Direct

Name: hypE [H]

Synonym: AZC_0612

Alternate gene names: 158422236

Gene position: 677681-678748 (Clockwise)

Preceding gene: 158422235

Following gene: 158422237

Centisome position: 12.62

GC content: 70.6

Gene sequence:

>1068_bases
ATGAACGGACCCTTCTCCCTTCCCCGCCGCGCGCCCCGCAAGGTGACGCAGCCCAAGGTGACGCTGGCCCATGGCGGCGG
CGGCACTGCCATGCGCGATCTCATCGAGGACGTGTTTCTCGAAACCTTCTCCGGCGCCGGCCACGCGGCCCCGGAGGATC
AGGCGCGGTTCGACCTGAGCGCGCTGGCGGCGCAGGGCGACCGCCTCGCCTTCACCACGGATGCCTTCGTGGTCGATCCG
CTCTTCTTCCCCGGCGGCGACATCGGCAAGCTCGCCGTCTGCGGCACGATCAACGATCTGGCGGTGGGCGGCGCCCGCCC
GGTGGCGCTCTCCTGCGCCGTCATCATCGAGGAAGGCCTGCCCCTGGAGACGCTGCGGGCCGTAGTCGCTTCCATGGCCC
GCACGGCTGCAGAAGCAGGTGTCGTCATCGTCACGGGCGACACCAAGGTCGTGGCGCGCGGCGCCTGCGACAAGCTCTTC
CTCACCACCACCGGCATCGGCGTGGTGCGAACGGGGCTCGATGTCGGCATCGCCAAGGGGCGCCCCGGCGATGTGGTGCT
GGTGAACGGTCTGCTCGGCGACCATGGCGCCGCCATCCTCAATGCGCGCGGCGACCTCGCGCTGGAGACGCCCATTGAGA
GCGACTGCGCGCCCCTGCATGATCTCGTCGCCACCTTGATCGCGGCAGCCCCCGGCATCCGCATGATGCGCGATGCCACG
CGCGGCGGCGTCGCCGCCGTCCTCAACGAGCTGGCGGAGGCGAGCGGCGTCGGCGTGCGCATCCGCGAGACCGACGTGCC
GCTGCGGCCCGAAGTGAACGGCTTCTGCGAGATCCTCGGCCTCGATCCGCTCTATCTCGCCAACGAGGGCAAGCTTGTCG
CCGTCGTGCCTCCCGAAGAAGCTGAGGCAGCGCTTGCCGCCGTGCGCGCCCATCTCCTCGGCCGGGAGGCCGCGATCATC
GGGCGGCTTGCCGCCGAGCGGCCCGGCCGCGTGGTCATGGAAACCCGCTTCGGCGGGGAGCGCATCGTGGACATGCTGGT
GGGAGATCAGTTGCCGCGGATCTGCTGA

Upstream 100 bases:

>100_bases
GCACCACCTGCACGCCGGAGATGCCGCTCGGCGCCCTTATGGTGTCATCCGAGGGCGCTTGCGCGGCCTATTACCAATAT
GGCGGCCTGCGGGGGGCAGC

Downstream 100 bases:

>100_bases
CGCCAAGCATTGAATTGTGCATTGCAATCACGCAAAAATCGCCAACCTTCCGAGGAGCTTGTTTGATGACCCGTCTTCCC
CTCCGTACGCTCGGCCTTGC

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNGPFSLPRRAPRKVTQPKVTLAHGGGGTAMRDLIEDVFLETFSGAGHAAPEDQARFDLSALAAQGDRLAFTTDAFVVDP
LFFPGGDIGKLAVCGTINDLAVGGARPVALSCAVIIEEGLPLETLRAVVASMARTAAEAGVVIVTGDTKVVARGACDKLF
LTTTGIGVVRTGLDVGIAKGRPGDVVLVNGLLGDHGAAILNARGDLALETPIESDCAPLHDLVATLIAAAPGIRMMRDAT
RGGVAAVLNELAEASGVGVRIRETDVPLRPEVNGFCEILGLDPLYLANEGKLVAVVPPEEAEAALAAVRAHLLGREAAII
GRLAAERPGRVVMETRFGGERIVDMLVGDQLPRIC

Sequences:

>Translated_355_residues
MNGPFSLPRRAPRKVTQPKVTLAHGGGGTAMRDLIEDVFLETFSGAGHAAPEDQARFDLSALAAQGDRLAFTTDAFVVDP
LFFPGGDIGKLAVCGTINDLAVGGARPVALSCAVIIEEGLPLETLRAVVASMARTAAEAGVVIVTGDTKVVARGACDKLF
LTTTGIGVVRTGLDVGIAKGRPGDVVLVNGLLGDHGAAILNARGDLALETPIESDCAPLHDLVATLIAAAPGIRMMRDAT
RGGVAAVLNELAEASGVGVRIRETDVPLRPEVNGFCEILGLDPLYLANEGKLVAVVPPEEAEAALAAVRAHLLGREAAII
GRLAAERPGRVVMETRFGGERIVDMLVGDQLPRIC
>Mature_355_residues
MNGPFSLPRRAPRKVTQPKVTLAHGGGGTAMRDLIEDVFLETFSGAGHAAPEDQARFDLSALAAQGDRLAFTTDAFVVDP
LFFPGGDIGKLAVCGTINDLAVGGARPVALSCAVIIEEGLPLETLRAVVASMARTAAEAGVVIVTGDTKVVARGACDKLF
LTTTGIGVVRTGLDVGIAKGRPGDVVLVNGLLGDHGAAILNARGDLALETPIESDCAPLHDLVATLIAAAPGIRMMRDAT
RGGVAAVLNELAEASGVGVRIRETDVPLRPEVNGFCEILGLDPLYLANEGKLVAVVPPEEAEAALAAVRAHLLGREAAII
GRLAAERPGRVVMETRFGGERIVDMLVGDQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=54.5994065281899, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36719; Mature: 36719

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPFSLPRRAPRKVTQPKVTLAHGGGGTAMRDLIEDVFLETFSGAGHAAPEDQARFDLS
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALAAQGDRLAFTTDAFVVDPLFFPGGDIGKLAVCGTINDLAVGGARPVALSCAVIIEEGL
HHHCCCCEEEEEECCEEECCEECCCCCCCCEEEECCCHHHHCCCCCCHHEEEEEEEECCC
PLETLRAVVASMARTAAEAGVVIVTGDTKVVARGACDKLFLTTTGIGVVRTGLDVGIAKG
CHHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCEEEEEECCCHHEECCCCEEECCC
RPGDVVLVNGLLGDHGAAILNARGDLALETPIESDCAPLHDLVATLIAAAPGIRMMRDAT
CCCCEEEEECCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHC
RGGVAAVLNELAEASGVGVRIRETDVPLRPEVNGFCEILGLDPLYLANEGKLVAVVPPEE
CCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCCH
AEAALAAVRAHLLGREAAIIGRLAAERPGRVVMETRFGGERIVDMLVGDQLPRIC
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNGPFSLPRRAPRKVTQPKVTLAHGGGGTAMRDLIEDVFLETFSGAGHAAPEDQARFDLS
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALAAQGDRLAFTTDAFVVDPLFFPGGDIGKLAVCGTINDLAVGGARPVALSCAVIIEEGL
HHHCCCCEEEEEECCEEECCEECCCCCCCCEEEECCCHHHHCCCCCCHHEEEEEEEECCC
PLETLRAVVASMARTAAEAGVVIVTGDTKVVARGACDKLFLTTTGIGVVRTGLDVGIAKG
CHHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCEEEEEECCCHHEECCCCEEECCC
RPGDVVLVNGLLGDHGAAILNARGDLALETPIESDCAPLHDLVATLIAAAPGIRMMRDAT
CCCCEEEEECCCCCCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHC
RGGVAAVLNELAEASGVGVRIRETDVPLRPEVNGFCEILGLDPLYLANEGKLVAVVPPEE
CCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCCH
AEAALAAVRAHLLGREAAIIGRLAAERPGRVVMETRFGGERIVDMLVGDQLPRIC
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]