Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 158422182

GI number: 158422182

Start: 618175

End: 619359

Strand: Direct

Name: aspC [H]

Synonym: AZC_0558

Alternate gene names: 158422182

Gene position: 618175-619359 (Clockwise)

Preceding gene: 158422177

Following gene: 158422183

Centisome position: 11.51

GC content: 66.41

Gene sequence:

>1185_bases
ATGCTGACCACCGTTGCCGCCTTCGACCGCATCGGCGAGGAGAATGCCTTTGCCGTGCTGGCGCGCGCCACGACGCTTGC
CGCCCAGGGGCGCGACATCATCAATCTCGGCATCGGCCAGCCGGATTTCCGCACGCCCGAGCATATCGTCGAGGCGGCCG
TGAAGGCGCTGAAGGACGGCCAGCACGGCTATACCCCCTCGGTCGGCATCCAGCCGCTGCGCGAGGCGGTGGCGCGCGAT
CTGCACAAGCGGTTCGATGTGGAGGTGGACCCCGGCCTCGTGATGATCATGCCCGGCGGCAAGGTCACCATGTATGCGGC
CATCCTGCTGTTCGGCGAGCCGGGCGCGGAAATCCTCTATCCGGACCCCGGCTTCCCCATCTACCGATCCATGATCGAAT
ATACGGGCGCGACCCCGATCCCGGTGCCGATCCGCGAGGAGAACGGCTTTGCCTTCTCGGCGGAAGAGACGCTGGCGCTG
ATCACACCCAAGACGCGCCTTCTCATCATCAATTCGCCGGCCAATCCCACCGGCGGCGTGACGCCCAAGGCCGAGATCGA
CAAGCTGGTGAAGGGCCTCGCCGATCATCCGCACGTGGCGCTGATGTCGGACGAGATCTACGACCAGTTCCTGTTTGATG
GCGAGCGCCACCAGACGCTGCTGGCTTACCCCGAAATCCGCGACCGCCTCATCCTGCTCAACGGCTGGTCGAAGACCTAT
GCCATGACCGGCTGGCGCCTCGGCTATTCCATCTGGCCCCAGGCGCTCTATGACAAGGTGCGCAAGCTCTCGGTGAATGC
CTGGTCGTGCGTCAATGCGGCGACCCAATATGCCGGCATCGCGGCGCTGGAAGGCCCGCAGGAGCCGGTGGCGGCCATGC
TCGCGGAGTTCGACAAGCGCCGGAGGCTGGTGGTGGAAGGGCTCAACGCGCTGCCCGGCGTCACCTGCGCCAAGCCCAAA
GGCGCCTTCTATGCCTTTCCCAATGTCTCGCGCACCGGCTGGACCTCGGCCAAGGCCCTCGCCTCCGCGCTGCTGGAGGA
CGCGGGCGTCGCGACCATCGGGGGGCCGGACTTCGGCGTTCATGGGGAGGGCTATATCCGCCTCTCCTATGCCAATTCGG
CGGAGAACATCGCCCGCGCGCTGGAGCGCATGGGCGCGTTCCTCTCCGAGCGCAAGGTCGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCCCGTTCATGCGGCGCGCCCGGAAGCCCCCAGCTCACCCGGACAACACGAGGACAGGGAATGGGTTCCGGCCAAA
GCCGGCCCGAGGAGAACGCC

Downstream 100 bases:

>100_bases
ATGGCGCGCGCCGGCCGGACGCTGGCGCGCCTTGGCGCCGGGATGCTCCTCCTCGCCGCCGCCCCGGCGGGGGCGCAGGA
GAAGCCCTGGCGCGAGCCAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLTTVAAFDRIGEENAFAVLARATTLAAQGRDIINLGIGQPDFRTPEHIVEAAVKALKDGQHGYTPSVGIQPLREAVARD
LHKRFDVEVDPGLVMIMPGGKVTMYAAILLFGEPGAEILYPDPGFPIYRSMIEYTGATPIPVPIREENGFAFSAEETLAL
ITPKTRLLIINSPANPTGGVTPKAEIDKLVKGLADHPHVALMSDEIYDQFLFDGERHQTLLAYPEIRDRLILLNGWSKTY
AMTGWRLGYSIWPQALYDKVRKLSVNAWSCVNAATQYAGIAALEGPQEPVAAMLAEFDKRRRLVVEGLNALPGVTCAKPK
GAFYAFPNVSRTGWTSAKALASALLEDAGVATIGGPDFGVHGEGYIRLSYANSAENIARALERMGAFLSERKVA

Sequences:

>Translated_394_residues
MLTTVAAFDRIGEENAFAVLARATTLAAQGRDIINLGIGQPDFRTPEHIVEAAVKALKDGQHGYTPSVGIQPLREAVARD
LHKRFDVEVDPGLVMIMPGGKVTMYAAILLFGEPGAEILYPDPGFPIYRSMIEYTGATPIPVPIREENGFAFSAEETLAL
ITPKTRLLIINSPANPTGGVTPKAEIDKLVKGLADHPHVALMSDEIYDQFLFDGERHQTLLAYPEIRDRLILLNGWSKTY
AMTGWRLGYSIWPQALYDKVRKLSVNAWSCVNAATQYAGIAALEGPQEPVAAMLAEFDKRRRLVVEGLNALPGVTCAKPK
GAFYAFPNVSRTGWTSAKALASALLEDAGVATIGGPDFGVHGEGYIRLSYANSAENIARALERMGAFLSERKVA
>Mature_394_residues
MLTTVAAFDRIGEENAFAVLARATTLAAQGRDIINLGIGQPDFRTPEHIVEAAVKALKDGQHGYTPSVGIQPLREAVARD
LHKRFDVEVDPGLVMIMPGGKVTMYAAILLFGEPGAEILYPDPGFPIYRSMIEYTGATPIPVPIREENGFAFSAEETLAL
ITPKTRLLIINSPANPTGGVTPKAEIDKLVKGLADHPHVALMSDEIYDQFLFDGERHQTLLAYPEIRDRLILLNGWSKTY
AMTGWRLGYSIWPQALYDKVRKLSVNAWSCVNAATQYAGIAALEGPQEPVAAMLAEFDKRRRLVVEGLNALPGVTCAKPK
GAFYAFPNVSRTGWTSAKALASALLEDAGVATIGGPDFGVHGEGYIRLSYANSAENIARALERMGAFLSERKVA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=330, Percent_Identity=24.8484848484848, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI56713254, Length=330, Percent_Identity=24.8484848484848, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=324, Percent_Identity=25.3086419753086, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI169881279, Length=324, Percent_Identity=25.3086419753086, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4507369, Length=307, Percent_Identity=26.0586319218241, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI169881281, Length=321, Percent_Identity=22.1183800623053, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4885351, Length=337, Percent_Identity=24.0356083086053, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=29.2011019283747, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1786816, Length=362, Percent_Identity=28.1767955801105, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788627, Length=389, Percent_Identity=27.2493573264781, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787909, Length=346, Percent_Identity=22.8323699421965, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=281, Percent_Identity=26.6903914590747, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=281, Percent_Identity=26.6903914590747, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=25.7294429708223, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=284, Percent_Identity=25.7042253521127, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=375, Percent_Identity=24.2666666666667, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=232, Percent_Identity=28.0172413793103, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=350, Percent_Identity=22.2857142857143, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=366, Percent_Identity=24.3169398907104, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=23.9690721649485, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=23.9690721649485, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=23.9690721649485, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=23.9690721649485, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=23.8219895287958, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45551451, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641770, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641760, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641768, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641766, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641764, Length=410, Percent_Identity=25.3658536585366, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42739; Mature: 42739

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTVAAFDRIGEENAFAVLARATTLAAQGRDIINLGIGQPDFRTPEHIVEAAVKALKDG
CCCHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
QHGYTPSVGIQPLREAVARDLHKRFDVEVDPGLVMIMPGGKVTMYAAILLFGEPGAEILY
CCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCEEEEEEEEEECCCCCEEEE
PDPGFPIYRSMIEYTGATPIPVPIREENGFAFSAEETLALITPKTRLLIINSPANPTGGV
CCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEECCCEEEEECCCEEEEEEECCCCCCCCC
TPKAEIDKLVKGLADHPHVALMSDEIYDQFLFDGERHQTLLAYPEIRDRLILLNGWSKTY
CCHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCE
AMTGWRLGYSIWPQALYDKVRKLSVNAWSCVNAATQYAGIAALEGPQEPVAAMLAEFDKR
EECCEECCHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHH
RRLVVEGLNALPGVTCAKPKGAFYAFPNVSRTGWTSAKALASALLEDAGVATIGGPDFGV
HHHHHHHHHHCCCCEECCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCC
HGEGYIRLSYANSAENIARALERMGAFLSERKVA
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTTVAAFDRIGEENAFAVLARATTLAAQGRDIINLGIGQPDFRTPEHIVEAAVKALKDG
CCCHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
QHGYTPSVGIQPLREAVARDLHKRFDVEVDPGLVMIMPGGKVTMYAAILLFGEPGAEILY
CCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCEEEEEEEEEECCCCCEEEE
PDPGFPIYRSMIEYTGATPIPVPIREENGFAFSAEETLALITPKTRLLIINSPANPTGGV
CCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEECCCEEEEECCCEEEEEEECCCCCCCCC
TPKAEIDKLVKGLADHPHVALMSDEIYDQFLFDGERHQTLLAYPEIRDRLILLNGWSKTY
CCHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCE
AMTGWRLGYSIWPQALYDKVRKLSVNAWSCVNAATQYAGIAALEGPQEPVAAMLAEFDKR
EECCEECCHHHCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHH
RRLVVEGLNALPGVTCAKPKGAFYAFPNVSRTGWTSAKALASALLEDAGVATIGGPDFGV
HHHHHHHHHHCCCCEECCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCC
HGEGYIRLSYANSAENIARALERMGAFLSERKVA
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]