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The map label for this gene is yhdH [H]

Identifier: 158422178

GI number: 158422178

Start: 614325

End: 615329

Strand: Reverse

Name: yhdH [H]

Synonym: AZC_0554

Alternate gene names: 158422178

Gene position: 615329-614325 (Counterclockwise)

Preceding gene: 158422179

Following gene: 158422175

Centisome position: 11.46

GC content: 70.95

Gene sequence:

>1005_bases
TTGAGAGCGGAGCACGCCATGAGCACCGATACCTTCAAGGCCATCGTCGCCCGCAAGGCCGAGGGCGGCCAGAGCGTGGC
GCTGGAGCAGGCGGACGAGAGCCTGCTGCCCGCCGCCGACGTCACCGTGGATGTGGCCTGGTCCACGCTGAACTACAAGG
ACGGCCTCGCGCTGAAGGGGCTGGGACGCATCCTGCGCACCTTCCCCATGGCACCGGGCATCGATTTTGCCGGCACCGTC
CGCACCAGCGACAGCCCAGAATTCAAGCCCGGCGATCAGGTGATCCTCACCGGCTGGGGCGTGGGCGAAACCTGGTCCGG
CGGCTTCTCCGCGCGGGCTCGGGCCAGGTCCGAATGGCTGGTGAAGCTGCCCGAGGGCATGAGCCCCCGGCAGGCCATGG
CCATCGGCACCGCCGGCTTCACCGCCATGCTGTGCGTGATGGCGCTGGAACGCCACGGCATCGAGACCGGTGGCGAGGTT
CTGGTGACGGGTGCGGCCGGCGGCGTCGGCAGCATCGCGGTGCGGCTGCTCTCGCGGCTCGGCTACCGTGTGGTGGCGCT
CACCGGCCGGCCGGAGGAGGCCGGCTTCCTGACCGGTCTCGGCGCTTCGGAAATCCTTGATCGCGCGGTGCTTCAGGCGC
CCGGCAAGCCGATGCAGTCGGAGCGTTGGGCGGGTGTCGTCGATACGGTGGGCGGCACCATCCTCGCCAATGCCATCGCC
GCGACCAAGGCGGAGGGTGCGGTCGCCGCCTGCGGCCTTGCGGGCGGCACGGACCTGCCCACAACGGTCCTTCCCTTCAT
CCTGCGCGGCGTCTGCCTGCTGGGCGTCAATTCGGTCGACGCGCCCATGGCCCGCCGGCAGGACGCCTGGGCGCGCCTCG
CCCGCGAACTGACCCCCGCCGATCTCGACGGGCTGACGCAGGAAGTGGCTCTGGAGGACGTGCTCGGTCTCGCCGACGAC
ATCCTCGCCGGCAAGGTCCGCGGCCGCACGGTGGTGCGGATCTGA

Upstream 100 bases:

>100_bases
GCCGCTACATGGCGGCCGGCAGCGTCTTCACCGCCGTGGATATCGACCTCGCCTTGCTGGTGCGCCAGACGGAAGCGCTG
GCGGCCGAGTTCAAGGCCGG

Downstream 100 bases:

>100_bases
GGGGGCTGCTTCGCGACGTGGCTGGCAAGAGGAAGCTGCCCAGTAGTCGACGGCGCACCTCGCCAGGAGGTTGCAAGGAA
CTCAGACCGTCGTACCCCCC

Product: NADPH protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRAEHAMSTDTFKAIVARKAEGGQSVALEQADESLLPAADVTVDVAWSTLNYKDGLALKGLGRILRTFPMAPGIDFAGTV
RTSDSPEFKPGDQVILTGWGVGETWSGGFSARARARSEWLVKLPEGMSPRQAMAIGTAGFTAMLCVMALERHGIETGGEV
LVTGAAGGVGSIAVRLLSRLGYRVVALTGRPEEAGFLTGLGASEILDRAVLQAPGKPMQSERWAGVVDTVGGTILANAIA
ATKAEGAVAACGLAGGTDLPTTVLPFILRGVCLLGVNSVDAPMARRQDAWARLARELTPADLDGLTQEVALEDVLGLADD
ILAGKVRGRTVVRI

Sequences:

>Translated_334_residues
MRAEHAMSTDTFKAIVARKAEGGQSVALEQADESLLPAADVTVDVAWSTLNYKDGLALKGLGRILRTFPMAPGIDFAGTV
RTSDSPEFKPGDQVILTGWGVGETWSGGFSARARARSEWLVKLPEGMSPRQAMAIGTAGFTAMLCVMALERHGIETGGEV
LVTGAAGGVGSIAVRLLSRLGYRVVALTGRPEEAGFLTGLGASEILDRAVLQAPGKPMQSERWAGVVDTVGGTILANAIA
ATKAEGAVAACGLAGGTDLPTTVLPFILRGVCLLGVNSVDAPMARRQDAWARLARELTPADLDGLTQEVALEDVLGLADD
ILAGKVRGRTVVRI
>Mature_334_residues
MRAEHAMSTDTFKAIVARKAEGGQSVALEQADESLLPAADVTVDVAWSTLNYKDGLALKGLGRILRTFPMAPGIDFAGTV
RTSDSPEFKPGDQVILTGWGVGETWSGGFSARARARSEWLVKLPEGMSPRQAMAIGTAGFTAMLCVMALERHGIETGGEV
LVTGAAGGVGSIAVRLLSRLGYRVVALTGRPEEAGFLTGLGASEILDRAVLQAPGKPMQSERWAGVVDTVGGTILANAIA
ATKAEGAVAACGLAGGTDLPTTVLPFILRGVCLLGVNSVDAPMARRQDAWARLARELTPADLDGLTQEVALEDVLGLADD
ILAGKVRGRTVVRI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=143, Percent_Identity=31.4685314685315, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI13236495, Length=143, Percent_Identity=31.4685314685315, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI194239676, Length=143, Percent_Identity=31.4685314685315, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789651, Length=324, Percent_Identity=51.2345679012346, Blast_Score=328, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 34730; Mature: 34730

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEHAMSTDTFKAIVARKAEGGQSVALEQADESLLPAADVTVDVAWSTLNYKDGLALKG
CCCCHHCCHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCCCEEEEEEEEECCCCCCCHHHH
LGRILRTFPMAPGIDFAGTVRTSDSPEFKPGDQVILTGWGVGETWSGGFSARARARSEWL
HHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCHHE
VKLPEGMSPRQAMAIGTAGFTAMLCVMALERHGIETGGEVLVTGAAGGVGSIAVRLLSRL
EECCCCCCCCHHHEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHC
GYRVVALTGRPEEAGFLTGLGASEILDRAVLQAPGKPMQSERWAGVVDTVGGTILANAIA
CCEEEEEECCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCHHHHHHHHH
ATKAEGAVAACGLAGGTDLPTTVLPFILRGVCLLGVNSVDAPMARRQDAWARLARELTPA
HHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
DLDGLTQEVALEDVLGLADDILAGKVRGRTVVRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MRAEHAMSTDTFKAIVARKAEGGQSVALEQADESLLPAADVTVDVAWSTLNYKDGLALKG
CCCCHHCCHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCCCEEEEEEEEECCCCCCCHHHH
LGRILRTFPMAPGIDFAGTVRTSDSPEFKPGDQVILTGWGVGETWSGGFSARARARSEWL
HHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCHHE
VKLPEGMSPRQAMAIGTAGFTAMLCVMALERHGIETGGEVLVTGAAGGVGSIAVRLLSRL
EECCCCCCCCHHHEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHC
GYRVVALTGRPEEAGFLTGLGASEILDRAVLQAPGKPMQSERWAGVVDTVGGTILANAIA
CCEEEEEECCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCHHHHHHHHH
ATKAEGAVAACGLAGGTDLPTTVLPFILRGVCLLGVNSVDAPMARRQDAWARLARELTPA
HHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
DLDGLTQEVALEDVLGLADDILAGKVRGRTVVRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]