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The map label for this gene is dapE [H]

Identifier: 158422176

GI number: 158422176

Start: 612090

End: 613262

Strand: Direct

Name: dapE [H]

Synonym: AZC_0552

Alternate gene names: 158422176

Gene position: 612090-613262 (Clockwise)

Preceding gene: 158422172

Following gene: 158422177

Centisome position: 11.4

GC content: 68.8

Gene sequence:

>1173_bases
GTGACCGACGCTGCCGCTTCCACCGCCGTTTCCGACCAAGCGCTTGCCTTCGCCAAGGCCCTGATTCAGGCCCCGTCCGT
GACGCCCGACGCCGGGCAGGCGCTGGACGTGGTGGCCGATGCGCTGAAGGCGGCGGGCTACCATGTGGAACGGCTGGTCT
TCTCTACGGCCGGCGTGCCGGTGGACAATCTCTATGCCCGCATCGGCACGGCCTCGCCCAATCTCTGCTTCGCCGGCCAT
GTGGACGTGGTGCCGCCGGGCGATGCGGCGTCCTGGCGGCATGGCCCCTTCTCCGGCGCGGTGGAGGACGGCGTGCTCTA
CGGGCGCGGGGCTGTGGACATGAAGGGGGCGGTGGCGGCCTTCCTCGCGGCGGCGCTGGCTTATGGCGCGCCGGCGCAGG
GCAGCCTCTCCTTCCTCATCACCGGCGATGAGGAAGGCCCCTCCATCGACGGCACCGCCAAGGTCGTGGACTGGCTCGCC
GCCAAGGGCGAAGTCATCGACCACTGCATCGTGGGCGAGCCCACCAATCCCAATGCGCTGGGCGATATGGTGAAGATCGG
CCGGCGCGGCAGCCTCTCCGGCCTCATCACCGTGGAGGGCCGGCAGGGCCACGTGGCCTATCCGCACCTCGCCGACAATC
CGGTGCCGCGCCTCGTGCGGCTCCTGACAGCGCTGACGGCGGCGCCGCTCGACAACGGCTCCGCGCATTTTCCACCCTCG
AACCTCGAGGTCATCAGCGTGGACGTGGGCAACACCGCCTACAACGTCATTCCCGGTGCCGCGACCGCCAAGTTCAACGT
GCGCTACAATGACCTCTACAGCCTCGAAAGCCTCATGGCGGAGATCGCCCGGCGACTCGACACGGCGGGAGAGCCCTATG
TCCTGACCTTCCGCGACGGGGCGAGCGAGAGCTTCCTCACCGCGCCGGGCCCGTTCGTGGAGACGGTGCTGGACGCGGTG
GCGGACGTGACCGGGCAGCGGCCGCAGATGTCCACCACCGGTGGCACGTCGGATGCGCGCTTCATCAAGTCGCTGTGCCC
GGTGGTTGAATTCGGCCTCGTCGGGCAGACCATGCACATGGTGAACGAGGCGACCCCCGTCGCCGATCTCACCGCCTTGA
CCGCCATCTATGAGCGGCTGATCGCGCGCTATTTCGCCACCTTCGCGGCTTGA

Upstream 100 bases:

>100_bases
CGGCAGCCTCGTGGCAGGGAAAAAGCCATTGACGGCGGCTGCCGCCCGCGCGAGGCAAGGGCAGTTCCCGCCCCACGTGC
GACCGTGACCGAGGCCTTCC

Downstream 100 bases:

>100_bases
GACAAGAAGGAGAACATTATGGCCGAGGAGACCTCCGGGCACCTGTCCGTCGATGGCATCGAGATCGCCACCCGCCGCGT
TCCGGGGCAGGGGCCGGGCG

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTDAAASTAVSDQALAFAKALIQAPSVTPDAGQALDVVADALKAAGYHVERLVFSTAGVPVDNLYARIGTASPNLCFAGH
VDVVPPGDAASWRHGPFSGAVEDGVLYGRGAVDMKGAVAAFLAAALAYGAPAQGSLSFLITGDEEGPSIDGTAKVVDWLA
AKGEVIDHCIVGEPTNPNALGDMVKIGRRGSLSGLITVEGRQGHVAYPHLADNPVPRLVRLLTALTAAPLDNGSAHFPPS
NLEVISVDVGNTAYNVIPGAATAKFNVRYNDLYSLESLMAEIARRLDTAGEPYVLTFRDGASESFLTAPGPFVETVLDAV
ADVTGQRPQMSTTGGTSDARFIKSLCPVVEFGLVGQTMHMVNEATPVADLTALTAIYERLIARYFATFAA

Sequences:

>Translated_390_residues
MTDAAASTAVSDQALAFAKALIQAPSVTPDAGQALDVVADALKAAGYHVERLVFSTAGVPVDNLYARIGTASPNLCFAGH
VDVVPPGDAASWRHGPFSGAVEDGVLYGRGAVDMKGAVAAFLAAALAYGAPAQGSLSFLITGDEEGPSIDGTAKVVDWLA
AKGEVIDHCIVGEPTNPNALGDMVKIGRRGSLSGLITVEGRQGHVAYPHLADNPVPRLVRLLTALTAAPLDNGSAHFPPS
NLEVISVDVGNTAYNVIPGAATAKFNVRYNDLYSLESLMAEIARRLDTAGEPYVLTFRDGASESFLTAPGPFVETVLDAV
ADVTGQRPQMSTTGGTSDARFIKSLCPVVEFGLVGQTMHMVNEATPVADLTALTAIYERLIARYFATFAA
>Mature_389_residues
TDAAASTAVSDQALAFAKALIQAPSVTPDAGQALDVVADALKAAGYHVERLVFSTAGVPVDNLYARIGTASPNLCFAGHV
DVVPPGDAASWRHGPFSGAVEDGVLYGRGAVDMKGAVAAFLAAALAYGAPAQGSLSFLITGDEEGPSIDGTAKVVDWLAA
KGEVIDHCIVGEPTNPNALGDMVKIGRRGSLSGLITVEGRQGHVAYPHLADNPVPRLVRLLTALTAAPLDNGSAHFPPSN
LEVISVDVGNTAYNVIPGAATAKFNVRYNDLYSLESLMAEIARRLDTAGEPYVLTFRDGASESFLTAPGPFVETVLDAVA
DVTGQRPQMSTTGGTSDARFIKSLCPVVEFGLVGQTMHMVNEATPVADLTALTAIYERLIARYFATFAA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=376, Percent_Identity=41.2234042553192, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1790395, Length=355, Percent_Identity=27.0422535211268, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 40483; Mature: 40352

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAASTAVSDQALAFAKALIQAPSVTPDAGQALDVVADALKAAGYHVERLVFSTAGVP
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
VDNLYARIGTASPNLCFAGHVDVVPPGDAASWRHGPFSGAVEDGVLYGRGAVDMKGAVAA
HHHHHHHHCCCCCCEEEECCEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHH
FLAAALAYGAPAQGSLSFLITGDEEGPSIDGTAKVVDWLAAKGEVIDHCIVGEPTNPNAL
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHEECCCCCCCHHH
GDMVKIGRRGSLSGLITVEGRQGHVAYPHLADNPVPRLVRLLTALTAAPLDNGSAHFPPS
HHHHHHCCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
NLEVISVDVGNTAYNVIPGAATAKFNVRYNDLYSLESLMAEIARRLDTAGEPYVLTFRDG
CCEEEEEECCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
ASESFLTAPGPFVETVLDAVADVTGQRPQMSTTGGTSDARFIKSLCPVVEFGLVGQTMHM
CCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNEATPVADLTALTAIYERLIARYFATFAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDAAASTAVSDQALAFAKALIQAPSVTPDAGQALDVVADALKAAGYHVERLVFSTAGVP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
VDNLYARIGTASPNLCFAGHVDVVPPGDAASWRHGPFSGAVEDGVLYGRGAVDMKGAVAA
HHHHHHHHCCCCCCEEEECCEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHH
FLAAALAYGAPAQGSLSFLITGDEEGPSIDGTAKVVDWLAAKGEVIDHCIVGEPTNPNAL
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHEECCCCCCCHHH
GDMVKIGRRGSLSGLITVEGRQGHVAYPHLADNPVPRLVRLLTALTAAPLDNGSAHFPPS
HHHHHHCCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
NLEVISVDVGNTAYNVIPGAATAKFNVRYNDLYSLESLMAEIARRLDTAGEPYVLTFRDG
CCEEEEEECCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
ASESFLTAPGPFVETVLDAVADVTGQRPQMSTTGGTSDARFIKSLCPVVEFGLVGQTMHM
CCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNEATPVADLTALTAIYERLIARYFATFAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA