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The map label for this gene is gap [H]

Identifier: 158422127

GI number: 158422127

Start: 560802

End: 561809

Strand: Reverse

Name: gap [H]

Synonym: AZC_0503

Alternate gene names: 158422127

Gene position: 561809-560802 (Counterclockwise)

Preceding gene: 158422128

Following gene: 158422126

Centisome position: 10.46

GC content: 66.67

Gene sequence:

>1008_bases
ATGACGGTGAAGGTGGCCATCAACGGGTTCGGTCGCATCGGGCGCAACGTGCTGCGCGCCATCATCGAATCCGGCCGCAC
CGACATCCAGGTGGTGGCCATCAACGACCTCGCCCCGGTCGAGACCAATGCCCACCTGCTGCGCTACGACAGCGTGCACG
GCCGCTTCCCGGCCAAGGTGGTGGTGAACGGCGACACCATCGACGTCGGCCAGGGCCCCATCAAGGTCACCGCCATCAAG
GATCCGTCCACCCTGCCCCACAAGGAGCTGGGCGTGGACATCGCCATGGAGTGCACGGGCATCTTCACCGCCCGTGACAA
GGCCGCAGCCCATCTCACCGCCGGCGCCAAGCGCGTGCTGGTATCGGCCCCCGCCGACGGCGCCGACCTCACGGTGGTCT
ATGGCGTGAACCACCAGCTCCTGAAGCCCGAGCACACGGTGGTCTCCAACGCCTCCTGCACCACCAACTGCCTCGCCCCG
GTGGCCAAGGTGCTCAACGACGCCGTTGGCATCGTCCACGGCTTCATGACCACCGTGCACTCCTACACCAACGACCAGCC
CTCGCTGGATCAGGTGCACAAGGATCTCTACCGCGCCCGCGCTGCCGCCCTCTCCATGATCCCGACCTCCACCGGCGCGG
CCAAGGCCGTCGGCCTCGTGCTGCCCGAGCTGAAGGGCAAGCTGGACGGCGTCTCCATCCGCGTGCCGACCCCGAACGTC
TCGGTCATCGACCTCAAGTTCGTCGCCAAGCGCGCCACGACGGTCGAAGAGATCAATGCCGCCATCAAGGCGGCGGCGGA
CGGCCCGCTGAAGGGCGTGCTCGGCTACACGACGGAGCCGAACGTCTCCATCGACTTCAACCACGACCCGCACTCGTCCA
CCTTCCACATGGACCAGACCAAGGTCATGGACGGCACGCTGGTGCGCGTCATGTCCTGGTATGACAACGAGTGGGGCTTC
TCCAACCGCATGTCCGACACCGCCGTCGCCCTGGCGAAGCTCGGTTGA

Upstream 100 bases:

>100_bases
TGCGGCCTACGGGCCCATGCGCCATACGAATTGCCGCCGGAGAAGGCGGCACGCGTTCGCTCAAGCCGGTCTTGAGGGCC
GGCGCATGGAGGATGAAGCT

Downstream 100 bases:

>100_bases
TCGGTTAAAGCGAGGGAGAGCAGCATCATGCCGACTTTCCGCACCCTCGATGAGGCGGACCTCGCCGGCAAGCGGGTCCT
CGTCCGTGTCGACCTCAACG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTVKVAINGFGRIGRNVLRAIIESGRTDIQVVAINDLAPVETNAHLLRYDSVHGRFPAKVVVNGDTIDVGQGPIKVTAIK
DPSTLPHKELGVDIAMECTGIFTARDKAAAHLTAGAKRVLVSAPADGADLTVVYGVNHQLLKPEHTVVSNASCTTNCLAP
VAKVLNDAVGIVHGFMTTVHSYTNDQPSLDQVHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVSIRVPTPNV
SVIDLKFVAKRATTVEEINAAIKAAADGPLKGVLGYTTEPNVSIDFNHDPHSSTFHMDQTKVMDGTLVRVMSWYDNEWGF
SNRMSDTAVALAKLG

Sequences:

>Translated_335_residues
MTVKVAINGFGRIGRNVLRAIIESGRTDIQVVAINDLAPVETNAHLLRYDSVHGRFPAKVVVNGDTIDVGQGPIKVTAIK
DPSTLPHKELGVDIAMECTGIFTARDKAAAHLTAGAKRVLVSAPADGADLTVVYGVNHQLLKPEHTVVSNASCTTNCLAP
VAKVLNDAVGIVHGFMTTVHSYTNDQPSLDQVHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVSIRVPTPNV
SVIDLKFVAKRATTVEEINAAIKAAADGPLKGVLGYTTEPNVSIDFNHDPHSSTFHMDQTKVMDGTLVRVMSWYDNEWGF
SNRMSDTAVALAKLG
>Mature_334_residues
TVKVAINGFGRIGRNVLRAIIESGRTDIQVVAINDLAPVETNAHLLRYDSVHGRFPAKVVVNGDTIDVGQGPIKVTAIKD
PSTLPHKELGVDIAMECTGIFTARDKAAAHLTAGAKRVLVSAPADGADLTVVYGVNHQLLKPEHTVVSNASCTTNCLAPV
AKVLNDAVGIVHGFMTTVHSYTNDQPSLDQVHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVSIRVPTPNVS
VIDLKFVAKRATTVEEINAAIKAAADGPLKGVLGYTTEPNVSIDFNHDPHSSTFHMDQTKVMDGTLVRVMSWYDNEWGFS
NRMSDTAVALAKLG

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=47.289156626506, Blast_Score=298, Evalue=7e-81,
Organism=Homo sapiens, GI7657116, Length=325, Percent_Identity=45.8461538461538, Blast_Score=275, Evalue=3e-74,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=49.1017964071856, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=49.7005988023952, Blast_Score=314, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=48.0825958702065, Blast_Score=303, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=47.787610619469, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=48.4939759036145, Blast_Score=292, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=48.4939759036145, Blast_Score=292, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=48.6567164179104, Blast_Score=304, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=49.2537313432836, Blast_Score=295, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=48.048048048048, Blast_Score=293, Evalue=2e-80,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=49.5384615384615, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=49.5384615384615, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=48.9230769230769, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=48.9230769230769, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=44.3076923076923, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35629; Mature: 35498

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKVAINGFGRIGRNVLRAIIESGRTDIQVVAINDLAPVETNAHLLRYDSVHGRFPAKV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEE
VVNGDTIDVGQGPIKVTAIKDPSTLPHKELGVDIAMECTGIFTARDKAAAHLTAGAKRVL
EECCCEEECCCCCEEEEEECCCCCCCHHHHCCEEEEEEEEEEEECCCHHHHHHCCCEEEE
VSAPADGADLTVVYGVNHQLLKPEHTVVSNASCTTNCLAPVAKVLNDAVGIVHGFMTTVH
EECCCCCCCEEEEEECCCCEECCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SYTNDQPSLDQVHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVSIRVPTPNV
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
SVIDLKFVAKRATTVEEINAAIKAAADGPLKGVLGYTTEPNVSIDFNHDPHSSTFHMDQT
EEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEECCCCCCCCEEECCHH
KVMDGTLVRVMSWYDNEWGFSNRMSDTAVALAKLG
HHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHEECC
>Mature Secondary Structure 
TVKVAINGFGRIGRNVLRAIIESGRTDIQVVAINDLAPVETNAHLLRYDSVHGRFPAKV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEE
VVNGDTIDVGQGPIKVTAIKDPSTLPHKELGVDIAMECTGIFTARDKAAAHLTAGAKRVL
EECCCEEECCCCCEEEEEECCCCCCCHHHHCCEEEEEEEEEEEECCCHHHHHHCCCEEEE
VSAPADGADLTVVYGVNHQLLKPEHTVVSNASCTTNCLAPVAKVLNDAVGIVHGFMTTVH
EECCCCCCCEEEEEECCCCEECCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SYTNDQPSLDQVHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGVSIRVPTPNV
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCC
SVIDLKFVAKRATTVEEINAAIKAAADGPLKGVLGYTTEPNVSIDFNHDPHSSTFHMDQT
EEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEECCCCCCCCEEECCHH
KVMDGTLVRVMSWYDNEWGFSNRMSDTAVALAKLG
HHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]