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The map label for this gene is ycgM [C]

Identifier: 158422096

GI number: 158422096

Start: 529223

End: 529996

Strand: Direct

Name: ycgM [C]

Synonym: AZC_0472

Alternate gene names: 158422096

Gene position: 529223-529996 (Clockwise)

Preceding gene: 158422095

Following gene: 158422098

Centisome position: 9.86

GC content: 66.67

Gene sequence:

>774_bases
ATGGCAAAATGGGTGCGGTTCACGGATGGTGCGGCGACGGGCTTCGGCCGCGTCGAGGGCGACCAGATCGCGGTGCATTC
GGGCGACATGTTCGGCGCGGCGCAGCCGACAGGCGAGACCCGCCCGCTCGCGGGCGCGCAACTCGCCGCGCCCTGCGATC
CCACCAAGATCATCGCGCTGTGGAACAATTTCCACGGCCTTGCGGCCAAGCTGAACGTGGCCGAGCCGGCCGAGCCGCTC
TATCTGCTGAAGTCCACCACGACGGTCGCCGCCCCCGATGCCGAAGTGCGCCGCCCGCCGGCCTATTCGGGCAAGACGGT
CTATGAGGGCGAACTCGGCATCGTCATCGGCAGGACCGCCCGCAACATCAGCGAGGACGAGGCGGCCGAACACATCTTCG
GCTACACCATCGTCAACGATCTGACCGCGGCCGACATCCTGAACAAGGATCCCACCTTCCCGCAGTGGGCGCGGGCGAAG
GGCTTCGACGGCTACGGTCCGTTCGGCCCCTGGATCGTCACCGATCTCGATCCCGCCACGGCCAGCGTGCGCACCGTGCT
CAATGGCGCCGAGCGGCAGAACTATCCGCTCTCAGACATGATCTTCCCGCCGGCGAAGCTGGTGGCGCTGCTGTCGCAGG
ACATGACACTCAATCCGGGAGATCTCATCGCCTGCGGCACGTCCATCGGCGTCGGCTCCATGAAGGAGCCGCGCAACGAG
GTGGACGTCAGCATCGATGGCATCGGCACGCTGCGCACCATCTTCGTGCAGTAG

Upstream 100 bases:

>100_bases
ACAATGAGGAACGCCGGCATCGCGAGCTGATGGCGAGCCTCAACGGCCAACGCACGCGCTGACGCCGCTCTCCCGCGGCG
GGCGCCACGGGAGGGACATC

Downstream 100 bases:

>100_bases
CCGCCGTGTTGGCGGGACCGCGGGCGGGGGGGCTGCGCGCGGTCCGCAAGCCTTGAGGTAAGGAGCTTCAGCCCCCCAGT
TCTTCCTTCAGGATTTCGAG

Product: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAKWVRFTDGAATGFGRVEGDQIAVHSGDMFGAAQPTGETRPLAGAQLAAPCDPTKIIALWNNFHGLAAKLNVAEPAEPL
YLLKSTTTVAAPDAEVRRPPAYSGKTVYEGELGIVIGRTARNISEDEAAEHIFGYTIVNDLTAADILNKDPTFPQWARAK
GFDGYGPFGPWIVTDLDPATASVRTVLNGAERQNYPLSDMIFPPAKLVALLSQDMTLNPGDLIACGTSIGVGSMKEPRNE
VDVSIDGIGTLRTIFVQ

Sequences:

>Translated_257_residues
MAKWVRFTDGAATGFGRVEGDQIAVHSGDMFGAAQPTGETRPLAGAQLAAPCDPTKIIALWNNFHGLAAKLNVAEPAEPL
YLLKSTTTVAAPDAEVRRPPAYSGKTVYEGELGIVIGRTARNISEDEAAEHIFGYTIVNDLTAADILNKDPTFPQWARAK
GFDGYGPFGPWIVTDLDPATASVRTVLNGAERQNYPLSDMIFPPAKLVALLSQDMTLNPGDLIACGTSIGVGSMKEPRNE
VDVSIDGIGTLRTIFVQ
>Mature_256_residues
AKWVRFTDGAATGFGRVEGDQIAVHSGDMFGAAQPTGETRPLAGAQLAAPCDPTKIIALWNNFHGLAAKLNVAEPAEPLY
LLKSTTTVAAPDAEVRRPPAYSGKTVYEGELGIVIGRTARNISEDEAAEHIFGYTIVNDLTAADILNKDPTFPQWARAKG
FDGYGPFGPWIVTDLDPATASVRTVLNGAERQNYPLSDMIFPPAKLVALLSQDMTLNPGDLIACGTSIGVGSMKEPRNEV
DVSIDGIGTLRTIFVQ

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=207, Percent_Identity=31.8840579710145, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI156231349, Length=213, Percent_Identity=31.4553990610329, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI13654274, Length=199, Percent_Identity=30.6532663316583, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=31.1224489795918, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=31.1224489795918, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1787428, Length=210, Percent_Identity=31.4285714285714, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17557057, Length=181, Percent_Identity=32.5966850828729, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324161, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28572127, Length=208, Percent_Identity=33.1730769230769, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24663695, Length=199, Percent_Identity=31.6582914572864, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571789, Length=185, Percent_Identity=32.4324324324324, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27386; Mature: 27255

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKWVRFTDGAATGFGRVEGDQIAVHSGDMFGAAQPTGETRPLAGAQLAAPCDPTKIIAL
CCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEE
WNNFHGLAAKLNVAEPAEPLYLLKSTTTVAAPDAEVRRPPAYSGKTVYEGELGIVIGRTA
ECCCCCEEEEEECCCCCCCEEEEECCCEEECCCHHHCCCCCCCCCEEEECCEEEEEECCC
RNISEDEAAEHIFGYTIVNDLTAADILNKDPTFPQWARAKGFDGYGPFGPWIVTDLDPAT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCHH
ASVRTVLNGAERQNYPLSDMIFPPAKLVALLSQDMTLNPGDLIACGTSIGVGSMKEPRNE
HHHHHHHCCHHCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCC
VDVSIDGIGTLRTIFVQ
EEEEECCCCEEEEEEEC
>Mature Secondary Structure 
AKWVRFTDGAATGFGRVEGDQIAVHSGDMFGAAQPTGETRPLAGAQLAAPCDPTKIIAL
CCEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEE
WNNFHGLAAKLNVAEPAEPLYLLKSTTTVAAPDAEVRRPPAYSGKTVYEGELGIVIGRTA
ECCCCCEEEEEECCCCCCCEEEEECCCEEECCCHHHCCCCCCCCCEEEECCEEEEEECCC
RNISEDEAAEHIFGYTIVNDLTAADILNKDPTFPQWARAKGFDGYGPFGPWIVTDLDPAT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCHH
ASVRTVLNGAERQNYPLSDMIFPPAKLVALLSQDMTLNPGDLIACGTSIGVGSMKEPRNE
HHHHHHHCCHHCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCC
VDVSIDGIGTLRTIFVQ
EEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]