Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 158422094

GI number: 158422094

Start: 527380

End: 528630

Strand: Direct

Name: frc [H]

Synonym: AZC_0470

Alternate gene names: 158422094

Gene position: 527380-528630 (Clockwise)

Preceding gene: 158422093

Following gene: 158422095

Centisome position: 9.82

GC content: 65.23

Gene sequence:

>1251_bases
ATGTCGAAGCCACTCGAGGGTATCAAGATCATCGACTTCACCCATGTGCAGGCCGGCCCCGCCTGCACGCAGCTGCTGGC
CTGGTTCGGCGCTGACGTGATCAAGGTGGAGCGTCCGGGCGCTGGCGACGTGACCCGCAGCCAGCTGCGCGACATTTCCA
ACGCCGACGCGCTCTACTTCACCATGCTGAACTCCAACAAGCGCTCGCTCACCCTGGACACCAAGACCCCCCAGGGCAAG
GAAGTGCTCACGAAGCTCATCAAGGAGAGCGACGTGCTGGTGGAGAACTTCGGTCCCGGCGCGCTGGACCGCATGGGCTT
CACCTGGGAGCACATCAAGGAGCTCAACCCCGGCATGATCGTCGCCTCGGTGAAGGGCTTCTCCGACGGCCACCACTATG
AAGACCTGAAGGTGTACGAGAACGTCGCGCAGTGCGCTGGCGGCGCCGCCTCCACCACCGGCTTCTGGGATGGCCCGCCC
ACCGTTTCGGCGGCTGCGCTCGGTGACAGCAACACCGGCATGCACCTCGCCATCGGCATCCTCACGGCGCTGCACGCCCG
CAACAAGACCGGCAAGGGCCAGAAGGTCGCCGTGTCCATGCAGGACTCGGTCATCAACCTCTGCCGCGTGAAGCTGCGCG
ACCAGCAGCGCCTCGACCGCGTCGGCTACCTCGAGGAGTATCCGCAGTATCCGCACGGCACCTTCTCGGATGTCGTGCCG
CGCGGCGGCAATGCGGGCGGCGGCGGCCAGCCCGGCTGGGTGCTGAAGTGCAAGGGCTGGGAGACCGATCCCAACGCCTA
CATCTACTTCACCATCCAGGGCCATGCCTGGGCCCCCATCTGCCGCGCCCTCGGCAAGGAAGAGTGGATCGACGATCCGG
CCTACAACACGGCGGAAGCCCGTCAGGACAAGATCTTCGAGATCTTCGCCTTCATCGAGGCCTGGCTCGCGGACAAGACC
AAGTTCGAGGCGGTGGACATCCTGCGCAAGTTCGACATCCCCTGCGCGCCGGTGCTCACCATGAAGGAGATCGCCAACGA
TCCGTCCCTGCGTGAGAGCGGCACCATCGTGGAAGTCGATCACAAGCAGCGCGGCAAGTACCTCACCGTCGGTTCGCCCA
TCAAGTTCTCGGACATGACGGTGGAAATCACCGGCTCGCCGCTGCTGGGCGAGCACACCGACGAAGTGCTGGCCGACCTC
GGCTACACCCCCGAGCAGATCAAGGCCCTGCACGAGGCGCGCGCGGTCTGA

Upstream 100 bases:

>100_bases
GCAATGGGCCCGATCCGCTTGCTGCCATCAGAAGAGTCGTGACGCCAGCAGTTCGCTTCCGCGCGAGGCGCGAAGCAAGA
CGTTGAAAGGGAGAATGCAC

Downstream 100 bases:

>100_bases
TTGGCGCATCCGGCCGACCGGGTCGATGGACCCGGCCGGCCCCGCGTTCGGCCCGCCGCGATAGCGGCGGGCCTTTTCTT
CCGGGACGCAGCGACCGCGC

Product: formyl-coenzyme A transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSKPLEGIKIIDFTHVQAGPACTQLLAWFGADVIKVERPGAGDVTRSQLRDISNADALYFTMLNSNKRSLTLDTKTPQGK
EVLTKLIKESDVLVENFGPGALDRMGFTWEHIKELNPGMIVASVKGFSDGHHYEDLKVYENVAQCAGGAASTTGFWDGPP
TVSAAALGDSNTGMHLAIGILTALHARNKTGKGQKVAVSMQDSVINLCRVKLRDQQRLDRVGYLEEYPQYPHGTFSDVVP
RGGNAGGGGQPGWVLKCKGWETDPNAYIYFTIQGHAWAPICRALGKEEWIDDPAYNTAEARQDKIFEIFAFIEAWLADKT
KFEAVDILRKFDIPCAPVLTMKEIANDPSLRESGTIVEVDHKQRGKYLTVGSPIKFSDMTVEITGSPLLGEHTDEVLADL
GYTPEQIKALHEARAV

Sequences:

>Translated_416_residues
MSKPLEGIKIIDFTHVQAGPACTQLLAWFGADVIKVERPGAGDVTRSQLRDISNADALYFTMLNSNKRSLTLDTKTPQGK
EVLTKLIKESDVLVENFGPGALDRMGFTWEHIKELNPGMIVASVKGFSDGHHYEDLKVYENVAQCAGGAASTTGFWDGPP
TVSAAALGDSNTGMHLAIGILTALHARNKTGKGQKVAVSMQDSVINLCRVKLRDQQRLDRVGYLEEYPQYPHGTFSDVVP
RGGNAGGGGQPGWVLKCKGWETDPNAYIYFTIQGHAWAPICRALGKEEWIDDPAYNTAEARQDKIFEIFAFIEAWLADKT
KFEAVDILRKFDIPCAPVLTMKEIANDPSLRESGTIVEVDHKQRGKYLTVGSPIKFSDMTVEITGSPLLGEHTDEVLADL
GYTPEQIKALHEARAV
>Mature_415_residues
SKPLEGIKIIDFTHVQAGPACTQLLAWFGADVIKVERPGAGDVTRSQLRDISNADALYFTMLNSNKRSLTLDTKTPQGKE
VLTKLIKESDVLVENFGPGALDRMGFTWEHIKELNPGMIVASVKGFSDGHHYEDLKVYENVAQCAGGAASTTGFWDGPPT
VSAAALGDSNTGMHLAIGILTALHARNKTGKGQKVAVSMQDSVINLCRVKLRDQQRLDRVGYLEEYPQYPHGTFSDVVPR
GGNAGGGGQPGWVLKCKGWETDPNAYIYFTIQGHAWAPICRALGKEEWIDDPAYNTAEARQDKIFEIFAFIEAWLADKTK
FEAVDILRKFDIPCAPVLTMKEIANDPSLRESGTIVEVDHKQRGKYLTVGSPIKFSDMTVEITGSPLLGEHTDEVLADLG
YTPEQIKALHEARAV

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=403, Percent_Identity=28.5359801488834, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI300863124, Length=429, Percent_Identity=26.8065268065268, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI42794625, Length=420, Percent_Identity=27.3809523809524, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI266456254, Length=420, Percent_Identity=27.3809523809524, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI300863126, Length=152, Percent_Identity=40.7894736842105, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI13376042, Length=429, Percent_Identity=23.3100233100233, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI266458397, Length=214, Percent_Identity=32.2429906542056, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI266458393, Length=214, Percent_Identity=32.2429906542056, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI266458395, Length=155, Percent_Identity=34.1935483870968, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI42822893, Length=155, Percent_Identity=34.1935483870968, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788717, Length=416, Percent_Identity=69.9519230769231, Blast_Score=583, Evalue=1e-168,
Organism=Escherichia coli, GI87082093, Length=396, Percent_Identity=28.7878787878788, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786222, Length=420, Percent_Identity=25, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32564160, Length=210, Percent_Identity=28.0952380952381, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115535051, Length=216, Percent_Identity=26.3888888888889, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648431, Length=415, Percent_Identity=31.8072289156626, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24585488, Length=198, Percent_Identity=29.7979797979798, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 45590; Mature: 45459

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLEGIKIIDFTHVQAGPACTQLLAWFGADVIKVERPGAGDVTRSQLRDISNADALYF
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCEEEE
TMLNSNKRSLTLDTKTPQGKEVLTKLIKESDVLVENFGPGALDRMGFTWEHIKELNPGMI
EEECCCCCEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCHHHHCCCCHHHHHHCCCCEE
VASVKGFSDGHHYEDLKVYENVAQCAGGAASTTGFWDGPPTVSAAALGDSNTGMHLAIGI
EEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHH
LTALHARNKTGKGQKVAVSMQDSVINLCRVKLRDQQRLDRVGYLEEYPQYPHGTFSDVVP
HHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHCC
RGGNAGGGGQPGWVLKCKGWETDPNAYIYFTIQGHAWAPICRALGKEEWIDDPAYNTAEA
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHCCHHHCCCCCCCCCHHH
RQDKIFEIFAFIEAWLADKTKFEAVDILRKFDIPCAPVLTMKEIANDPSLRESGTIVEVD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEC
HKQRGKYLTVGSPIKFSDMTVEITGSPLLGEHTDEVLADLGYTPEQIKALHEARAV
CCCCCCEEEECCCEEECCEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKPLEGIKIIDFTHVQAGPACTQLLAWFGADVIKVERPGAGDVTRSQLRDISNADALYF
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCEEEE
TMLNSNKRSLTLDTKTPQGKEVLTKLIKESDVLVENFGPGALDRMGFTWEHIKELNPGMI
EEECCCCCEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCHHHHCCCCHHHHHHCCCCEE
VASVKGFSDGHHYEDLKVYENVAQCAGGAASTTGFWDGPPTVSAAALGDSNTGMHLAIGI
EEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHH
LTALHARNKTGKGQKVAVSMQDSVINLCRVKLRDQQRLDRVGYLEEYPQYPHGTFSDVVP
HHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHCC
RGGNAGGGGQPGWVLKCKGWETDPNAYIYFTIQGHAWAPICRALGKEEWIDDPAYNTAEA
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHCCHHHCCCCCCCCCHHH
RQDKIFEIFAFIEAWLADKTKFEAVDILRKFDIPCAPVLTMKEIANDPSLRESGTIVEVD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEC
HKQRGKYLTVGSPIKFSDMTVEITGSPLLGEHTDEVLADLGYTPEQIKALHEARAV
CCCCCCEEEECCCEEECCEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA