Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 158422029

GI number: 158422029

Start: 457217

End: 458653

Strand: Direct

Name: mocR [H]

Synonym: AZC_0405

Alternate gene names: 158422029

Gene position: 457217-458653 (Clockwise)

Preceding gene: 158422026

Following gene: 158422033

Centisome position: 8.51

GC content: 74.53

Gene sequence:

>1437_bases
ATGCGCCGTTCCGACGAGACCAATCTTTCCGAGGCCGCTGCCCCGGAGGTCCATGCCGCCGACTGGTCGGCCTTGATCCC
GGTTCTGCCCAAGGCTGGCCCCCGGCCGGTGGCGCTCTATGCGGAACTGCGGCGGCTGATCGAAGGCGGCGTCCTGCGCC
CCGGCACCAAGCTGCCGCCGACGCGGGAGCTGGCGGCGCGGCTCGGCCTCTCGCGCGGGGCGGCTGTGGCGGCGTTCGAG
CTGCTGCTGGCGGAGGGCTTTGCCGAGGCGCGGGTGGGGGCGGGCACCTTCGTCGCCGCCGCCGTGCCGCAGATCGCACC
CGCCGCGCCGCCGCCGGACCCGCGCCCCGCGGTGGCGCCGCCGCTGCCCGGCGCGCTCGGCCTCGCGGCGCCCGACGCGC
GCACCTTCCAGATCCTGCGCGGGCTCATCACCCGCCATATGGCGGTGCCGGCGCGCCATCACTTCGGCTATGGCGATCCC
CGCGGCAGCCGGGCGCTCAGGGAGGAGGTGGCGGCCTATCTGCGCACGGCGCGCGGCGTGCGCTGCCATGGCGATCAAGT
GGTGCTGACCTCCGGCTCGCAGCAGGCGCTCGATCTCATCATCCGCGCGGCGCTCACGCCCGGCGATCCGGTGTGGATCG
AGGACCCCTGCTATCCCATGGCCCGCGCCGCCTTCGAGGGCGCCGGCATGCGCCTCATCGGCGTGCCGGTGGATGGGGAG
GGGCTCGATCCGGCGGCGGGGGAGGCGCGGGCGCCCCATGCGCGGGCGGTCTATGTGACACCCTCCCACCAGTTTCCGCT
CGGCGTTACCCTCACCATGGCCCGCCGCCTCGCCCTCATCGACTGGGCAAGGCGCGCCGGGGCCTGGATCATCGAGGACG
ATTACGACAGCGAATATCGCTATGCCGGCCCCCCGCTCACCGCTCTTCAGGGCATCGATGGGGCGGGGCGGGTGATCTAT
GTGGGCACCTTCTCCAAGGCGCTCTTTCCGGGCCTGCGGGTGGGCTATGCCGTGGTGCCGGAGGCGCTGCTGGACGCGGT
GATTGCCGTGCGCAACCGCTCGGACCGCTTCCCGCCCTCGCTGCTGGAGGACGCGCTGGCGGACTTCCTGCGCGAAGGGC
ATTTCTCCGCCCACCTGCGTCGCGCCCGCCGCCGCGCGCGCGACGCCCGCGATGCGCTGGTGGCCGTGCTGAATGAAGGC
GGGCTCTCGGTCGCCGCGCCCGATCAGGGCCTGCACCTCGTGGCCCGACGGCCCGACTGGACCGAGGACGCGACCCTGCT
CGCGGCGGCGCGGGCGGAGGGGTTCGGCCCCCGCGCGCTCTCGCCGCTCCATGTGGATCGGCCGCCTGAGGCCGGCCTCG
TCATCGGGTTTTCCGGCTTCCCGCCGGAGGAGCTGGCAAGCGCCGCCCGCCGCTGGCTGGCGCGGATCGGCGGGTGA

Upstream 100 bases:

>100_bases
TCGGATAAGCGTGTCTCGGTCGTCTCGTGGCTCATGACTTGCCTTTCTGCGCGGGCAGGCTCAGAGCTAGGCTCTGGATT
GGACCTGAGATAGATCCAAT

Downstream 100 bases:

>100_bases
GGGTCAGGCGGTTTCGTCGAGGCGCTTGGAGAAGACGACGCGCGGTTCGTCGAGATAGCCGAGCGCCTCATAGAAGCCGC
GCACCTTCTCATTGTCCGGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRRSDETNLSEAAAPEVHAADWSALIPVLPKAGPRPVALYAELRRLIEGGVLRPGTKLPPTRELAARLGLSRGAAVAAFE
LLLAEGFAEARVGAGTFVAAAVPQIAPAAPPPDPRPAVAPPLPGALGLAAPDARTFQILRGLITRHMAVPARHHFGYGDP
RGSRALREEVAAYLRTARGVRCHGDQVVLTSGSQQALDLIIRAALTPGDPVWIEDPCYPMARAAFEGAGMRLIGVPVDGE
GLDPAAGEARAPHARAVYVTPSHQFPLGVTLTMARRLALIDWARRAGAWIIEDDYDSEYRYAGPPLTALQGIDGAGRVIY
VGTFSKALFPGLRVGYAVVPEALLDAVIAVRNRSDRFPPSLLEDALADFLREGHFSAHLRRARRRARDARDALVAVLNEG
GLSVAAPDQGLHLVARRPDWTEDATLLAAARAEGFGPRALSPLHVDRPPEAGLVIGFSGFPPEELASAARRWLARIGG

Sequences:

>Translated_478_residues
MRRSDETNLSEAAAPEVHAADWSALIPVLPKAGPRPVALYAELRRLIEGGVLRPGTKLPPTRELAARLGLSRGAAVAAFE
LLLAEGFAEARVGAGTFVAAAVPQIAPAAPPPDPRPAVAPPLPGALGLAAPDARTFQILRGLITRHMAVPARHHFGYGDP
RGSRALREEVAAYLRTARGVRCHGDQVVLTSGSQQALDLIIRAALTPGDPVWIEDPCYPMARAAFEGAGMRLIGVPVDGE
GLDPAAGEARAPHARAVYVTPSHQFPLGVTLTMARRLALIDWARRAGAWIIEDDYDSEYRYAGPPLTALQGIDGAGRVIY
VGTFSKALFPGLRVGYAVVPEALLDAVIAVRNRSDRFPPSLLEDALADFLREGHFSAHLRRARRRARDARDALVAVLNEG
GLSVAAPDQGLHLVARRPDWTEDATLLAAARAEGFGPRALSPLHVDRPPEAGLVIGFSGFPPEELASAARRWLARIGG
>Mature_478_residues
MRRSDETNLSEAAAPEVHAADWSALIPVLPKAGPRPVALYAELRRLIEGGVLRPGTKLPPTRELAARLGLSRGAAVAAFE
LLLAEGFAEARVGAGTFVAAAVPQIAPAAPPPDPRPAVAPPLPGALGLAAPDARTFQILRGLITRHMAVPARHHFGYGDP
RGSRALREEVAAYLRTARGVRCHGDQVVLTSGSQQALDLIIRAALTPGDPVWIEDPCYPMARAAFEGAGMRLIGVPVDGE
GLDPAAGEARAPHARAVYVTPSHQFPLGVTLTMARRLALIDWARRAGAWIIEDDYDSEYRYAGPPLTALQGIDGAGRVIY
VGTFSKALFPGLRVGYAVVPEALLDAVIAVRNRSDRFPPSLLEDALADFLREGHFSAHLRRARRRARDARDALVAVLNEG
GLSVAAPDQGLHLVARRPDWTEDATLLAAARAEGFGPRALSPLHVDRPPEAGLVIGFSGFPPEELASAARRWLARIGG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=225, Percent_Identity=27.5555555555556, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI33469970, Length=225, Percent_Identity=27.5555555555556, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1790797, Length=360, Percent_Identity=29.1666666666667, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787710, Length=374, Percent_Identity=29.9465240641711, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 50855; Mature: 50855

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSDETNLSEAAAPEVHAADWSALIPVLPKAGPRPVALYAELRRLIEGGVLRPGTKLPP
CCCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
TRELAARLGLSRGAAVAAFELLLAEGFAEARVGAGTFVAAAVPQIAPAAPPPDPRPAVAP
HHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
PLPGALGLAAPDARTFQILRGLITRHMAVPARHHFGYGDPRGSRALREEVAAYLRTARGV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
RCHGDQVVLTSGSQQALDLIIRAALTPGDPVWIEDPCYPMARAAFEGAGMRLIGVPVDGE
EECCCEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHCCCCEEEEEECCCCC
GLDPAAGEARAPHARAVYVTPSHQFPLGVTLTMARRLALIDWARRAGAWIIEDDYDSEYR
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCE
YAGPPLTALQGIDGAGRVIYVGTFSKALFPGLRVGYAVVPEALLDAVIAVRNRSDRFPPS
ECCCCHHHHCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LLEDALADFLREGHFSAHLRRARRRARDARDALVAVLNEGGLSVAAPDQGLHLVARRPDW
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCC
TEDATLLAAARAEGFGPRALSPLHVDRPPEAGLVIGFSGFPPEELASAARRWLARIGG
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRSDETNLSEAAAPEVHAADWSALIPVLPKAGPRPVALYAELRRLIEGGVLRPGTKLPP
CCCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
TRELAARLGLSRGAAVAAFELLLAEGFAEARVGAGTFVAAAVPQIAPAAPPPDPRPAVAP
HHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
PLPGALGLAAPDARTFQILRGLITRHMAVPARHHFGYGDPRGSRALREEVAAYLRTARGV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
RCHGDQVVLTSGSQQALDLIIRAALTPGDPVWIEDPCYPMARAAFEGAGMRLIGVPVDGE
EECCCEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHCCCCEEEEEECCCCC
GLDPAAGEARAPHARAVYVTPSHQFPLGVTLTMARRLALIDWARRAGAWIIEDDYDSEYR
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCE
YAGPPLTALQGIDGAGRVIYVGTFSKALFPGLRVGYAVVPEALLDAVIAVRNRSDRFPPS
ECCCCHHHHCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LLEDALADFLREGHFSAHLRRARRRARDARDALVAVLNEGGLSVAAPDQGLHLVARRPDW
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCC
TEDATLLAAARAEGFGPRALSPLHVDRPPEAGLVIGFSGFPPEELASAARRWLARIGG
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]