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The map label for this gene is ahpC [C]

Identifier: 158422007

GI number: 158422007

Start: 438015

End: 438698

Strand: Direct

Name: ahpC [C]

Synonym: AZC_0383

Alternate gene names: 158422007

Gene position: 438015-438698 (Clockwise)

Preceding gene: 158422005

Following gene: 158422008

Centisome position: 8.16

GC content: 62.43

Gene sequence:

>684_bases
TTGATAGTCACATTTTCGATTTGTAGTTTGGAGGCATCCATGACGCTCCGCCTTGGCGATACGGTTCCCGACTTCACCGC
CCAGACCACCGAGGGGCCCATCAGCTTTCACGAGTGGCTCGGCAATTCGTGGGGCATCCTGTTCTCGCATCCGAAGAACT
TCACCCCCGTCTGCACCACCGAGCTGGGGCAGGTGGCGCATCTGAAGGGCGAGTTCGACAAGCGCAACGTGAAGGTCATC
GGCCTGTCCGTGGACACGATCGAAAACCATCCGGCCTGGGTCGCGGACATCAAGGACGCCACCGGCGCGAACCTGAATTT
CCCGCTCATCGCCGACAGCGACAAGAAGGTCTCCGACCTCTATGACCTGATCCATCCGAATGCGAGCGACACCGCCACCG
TGCGGTCCGTCTTCGTCATCGGGCCGGACAAGAAGCTGAAGCTGACGCTGACCTATCCGGCGAGCACGGGCCGCAACTTC
CAGGAAATCCTGCGCGTGGTGGATTCGCTCCAGCTCACCGCCCAGCATTCCGTCGCCACGCCGGTGGACTGGAAGCAGGG
CGATGACGTCATCATCGTCCCCTCCGTCTCCGACGAGGCGGCCAAGGAGAAGTTCCCGGAAGGCTGGAAGACGGTGAAGC
CCTATCTGCGCGTCGTGCGCCAGCCCGGCACCGCCTCCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCGGCTGGCCACTGCGGCCCCAACTGCGACCGATGCGCCATGTGGACAGGGGATAGGCCCTGCGTCTTCCAAACTTC
ATCGATCATGTGTATGATAT

Downstream 100 bases:

>100_bases
CGTACATCCCTTTGCATTAGCGCTGCCGCCTGCTCCTCGGGGCGGCGGCCTTTGCGCAGGTCTGCGCCCGCCGACTTGAC
CCCTCCTGCCCTCGCGATAG

Product: AhpC/TSA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MIVTFSICSLEASMTLRLGDTVPDFTAQTTEGPISFHEWLGNSWGILFSHPKNFTPVCTTELGQVAHLKGEFDKRNVKVI
GLSVDTIENHPAWVADIKDATGANLNFPLIADSDKKVSDLYDLIHPNASDTATVRSVFVIGPDKKLKLTLTYPASTGRNF
QEILRVVDSLQLTAQHSVATPVDWKQGDDVIIVPSVSDEAAKEKFPEGWKTVKPYLRVVRQPGTASA

Sequences:

>Translated_227_residues
MIVTFSICSLEASMTLRLGDTVPDFTAQTTEGPISFHEWLGNSWGILFSHPKNFTPVCTTELGQVAHLKGEFDKRNVKVI
GLSVDTIENHPAWVADIKDATGANLNFPLIADSDKKVSDLYDLIHPNASDTATVRSVFVIGPDKKLKLTLTYPASTGRNF
QEILRVVDSLQLTAQHSVATPVDWKQGDDVIIVPSVSDEAAKEKFPEGWKTVKPYLRVVRQPGTASA
>Mature_227_residues
MIVTFSICSLEASMTLRLGDTVPDFTAQTTEGPISFHEWLGNSWGILFSHPKNFTPVCTTELGQVAHLKGEFDKRNVKVI
GLSVDTIENHPAWVADIKDATGANLNFPLIADSDKKVSDLYDLIHPNASDTATVRSVFVIGPDKKLKLTLTYPASTGRNF
QEILRVVDSLQLTAQHSVATPVDWKQGDDVIIVPSVSDEAAKEKFPEGWKTVKPYLRVVRQPGTASA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=220, Percent_Identity=54.0909090909091, Blast_Score=232, Evalue=3e-61,
Organism=Homo sapiens, GI32189392, Length=199, Percent_Identity=31.6582914572864, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4505591, Length=200, Percent_Identity=32, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32455266, Length=200, Percent_Identity=32, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32455264, Length=200, Percent_Identity=32, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI5453549, Length=161, Percent_Identity=29.8136645962733, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=29.2207792207792, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25153706, Length=224, Percent_Identity=41.9642857142857, Blast_Score=177, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17554494, Length=212, Percent_Identity=30.188679245283, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204376, Length=179, Percent_Identity=27.9329608938547, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32565831, Length=179, Percent_Identity=27.9329608938547, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=51.8867924528302, Blast_Score=225, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=173, Percent_Identity=27.1676300578035, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581278, Length=217, Percent_Identity=48.3870967741936, Blast_Score=215, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24652434, Length=205, Percent_Identity=47.8048780487805, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24652436, Length=205, Percent_Identity=47.8048780487805, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=47.8048780487805, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI17738015, Length=197, Percent_Identity=28.4263959390863, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17157991, Length=168, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641739, Length=168, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656348, Length=160, Percent_Identity=31.25, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17864676, Length=160, Percent_Identity=31.25, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=25.2577319587629, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24889; Mature: 24889

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTFSICSLEASMTLRLGDTVPDFTAQTTEGPISFHEWLGNSWGILFSHPKNFTPVCTT
CEEEEEEEEECEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCEEHH
ELGQVAHLKGEFDKRNVKVIGLSVDTIENHPAWVADIKDATGANLNFPLIADSDKKVSDL
HCCCEEECCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHH
YDLIHPNASDTATVRSVFVIGPDKKLKLTLTYPASTGRNFQEILRVVDSLQLTAQHSVAT
HHHHCCCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
PVDWKQGDDVIIVPSVSDEAAKEKFPEGWKTVKPYLRVVRQPGTASA
CCCCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIVTFSICSLEASMTLRLGDTVPDFTAQTTEGPISFHEWLGNSWGILFSHPKNFTPVCTT
CEEEEEEEEECEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCEEHH
ELGQVAHLKGEFDKRNVKVIGLSVDTIENHPAWVADIKDATGANLNFPLIADSDKKVSDL
HCCCEEECCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHH
YDLIHPNASDTATVRSVFVIGPDKKLKLTLTYPASTGRNFQEILRVVDSLQLTAQHSVAT
HHHHCCCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
PVDWKQGDDVIIVPSVSDEAAKEKFPEGWKTVKPYLRVVRQPGTASA
CCCCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]