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The map label for this gene is lysK [H]

Identifier: 158422004

GI number: 158422004

Start: 433670

End: 435325

Strand: Direct

Name: lysK [H]

Synonym: AZC_0380

Alternate gene names: 158422004

Gene position: 433670-435325 (Clockwise)

Preceding gene: 158422003

Following gene: 158422005

Centisome position: 8.08

GC content: 65.1

Gene sequence:

>1656_bases
ATGACCACGGCCGCGACGACCGAAGACCTTGCCACCGAACTGCGCACGTTTGCGGAGACCGCAGGCGCCTGGCCGTTCGA
GGAAGCGCGCAAGATCGTCGAGCGGCTGAAGCGCAAGCCCAAGGACGAGGTGCTGTTCGAGACCGGCTATGGCCCCTCCG
GCCTGCCGCACATCGGCACGTTCGGCGAAGTGGCGCGCACCACCATGGTGCGCCACGCCTTCCGCGTGCTCACCGAGGAC
AAGGTGAAGACCCGGCTGCTGTGCTTCTCGGACGATATGGACGGCATGCGCAAGATCCCGGACAACGTGCCGGACCGCGC
CGCGCTGGAGCCCTATCTCCAGATGCCGCTGACCTCCGTGCCCAATCCGTTCGGCGGCGACTATCCGAGCTTCGGCGACC
ACAACAACGCCATGCTGCGGCGCTTCCTCGACACCTTTGGCTTCGATTACGAATTCGCCAGCGCTACCGATTATTACAAG
ACCGGCAAGCTGGACGCCGTGCTGCTGCGCGCGGCCGAGAAGTACGATGACATCATGGCCGTGATGCTGCCGACGCTCGG
CGAGGAGCGGCAGGCCACCTACAGCCCGTTCCTGCCCATCTCGCCCACCAGCGGGCGCGTGCTCTACGTGCCGCTGAAGG
CCGTGGACGCCAAGGCCGGCACCATCACCTTCACGGACGAGGACGGGGTGGACAAGACCCTCCCCGTGACCGGGGGCAAG
GTGAAGCTTCAGTGGAAGCCGGACTTCGGCGCCCGCTGGGCGGCGCTCGGCGTCGATTTCGAGATGTTCGGCAAGGATCA
CCAGACCAACGCGCCGGTCTATGACAGGATCTGCGAGATCCTCGGCGGCGTGGCGCCCGAGCATTATGTCTATGAGCTGT
TCCTCGATGAGAACGGCCAGAAGATCTCCAAGTCCAAGGGCAATGGCCTCACCATCGACGAGTGGCTGACTTACGCGAGC
CCGGAGAGCCTCGCGCTCTACATGTTCCAGTCGCCGCGCTCGGCCAAGAAGCTGCACTTCGACGTCATCCCGAAGGCGGT
GGACGAGTATTTCAACTTCCTCGCCCGCTATCCGGCGCAGGACTGGAAGCTGCGCCTCGGCAATCCGGTGTGGCACATCC
ATTCCGGCAATCCGCCGGCGGTGGACATGCCGGTGTCCTTCTCCATGCTGCTCAACCTCGCCTCGGCGTCCAACACCGAG
GACGAGGGCGTGCTGTGGGGCTTCCTCAACCGTCACGTGGAAGGTATCTCGCCTCAGACCCATCCCAAGCTCAACGAGCT
GGTGGGCTATGCGGTGAAGTATTTCAATGACTTCGTGAAGCCCAACAAGCGCTTCCGTGCCCCTGACGACGTTGAGCGGG
ACGCCCTCGCGACGCTCGATGCGGCGCTCGCCGCCTTGCCCGAGGGGGCGAGCGCGGAGGACATCCAGACGGTGCTCTAT
GACGTGGCCCGTCCCATCCCGCGCTATCAGGACCTCAAGGCCAAGGGCGCGACGCCGGAGAAGCCGGGCGTCTCGGTGGA
ATGGTTCAACACGATCTATCAGGTTCTGATCGGGCAGGAGCGGGGACCGCGCTTCGGCTCGTTCGTCGCCATCTACGGCA
TCCCGGAGACGCGGGCGCTCATCGCCAAGGCCCTCGACGGCACGCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCGAGCCCGGCCGTAGCCTTCCTTTCGAGGACGGCTGGCGCGGCCGCGCAGCCACCAGGCCGCCTGCCTCGCCCGTTGGC
GCCCTGACCGGAGATTTGAC

Downstream 100 bases:

>100_bases
GGCTTGACCGTCCGCGCTTTGCGCGGGCGGCGTCTCTTATCGATCGCTTGCTCTGGAGTGGCTTGGCCTCCGGCTGGCCC
GTTGCTCTAATCCCCGGCGA

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTTAATTEDLATELRTFAETAGAWPFEEARKIVERLKRKPKDEVLFETGYGPSGLPHIGTFGEVARTTMVRHAFRVLTED
KVKTRLLCFSDDMDGMRKIPDNVPDRAALEPYLQMPLTSVPNPFGGDYPSFGDHNNAMLRRFLDTFGFDYEFASATDYYK
TGKLDAVLLRAAEKYDDIMAVMLPTLGEERQATYSPFLPISPTSGRVLYVPLKAVDAKAGTITFTDEDGVDKTLPVTGGK
VKLQWKPDFGARWAALGVDFEMFGKDHQTNAPVYDRICEILGGVAPEHYVYELFLDENGQKISKSKGNGLTIDEWLTYAS
PESLALYMFQSPRSAKKLHFDVIPKAVDEYFNFLARYPAQDWKLRLGNPVWHIHSGNPPAVDMPVSFSMLLNLASASNTE
DEGVLWGFLNRHVEGISPQTHPKLNELVGYAVKYFNDFVKPNKRFRAPDDVERDALATLDAALAALPEGASAEDIQTVLY
DVARPIPRYQDLKAKGATPEKPGVSVEWFNTIYQVLIGQERGPRFGSFVAIYGIPETRALIAKALDGTLAA

Sequences:

>Translated_551_residues
MTTAATTEDLATELRTFAETAGAWPFEEARKIVERLKRKPKDEVLFETGYGPSGLPHIGTFGEVARTTMVRHAFRVLTED
KVKTRLLCFSDDMDGMRKIPDNVPDRAALEPYLQMPLTSVPNPFGGDYPSFGDHNNAMLRRFLDTFGFDYEFASATDYYK
TGKLDAVLLRAAEKYDDIMAVMLPTLGEERQATYSPFLPISPTSGRVLYVPLKAVDAKAGTITFTDEDGVDKTLPVTGGK
VKLQWKPDFGARWAALGVDFEMFGKDHQTNAPVYDRICEILGGVAPEHYVYELFLDENGQKISKSKGNGLTIDEWLTYAS
PESLALYMFQSPRSAKKLHFDVIPKAVDEYFNFLARYPAQDWKLRLGNPVWHIHSGNPPAVDMPVSFSMLLNLASASNTE
DEGVLWGFLNRHVEGISPQTHPKLNELVGYAVKYFNDFVKPNKRFRAPDDVERDALATLDAALAALPEGASAEDIQTVLY
DVARPIPRYQDLKAKGATPEKPGVSVEWFNTIYQVLIGQERGPRFGSFVAIYGIPETRALIAKALDGTLAA
>Mature_550_residues
TTAATTEDLATELRTFAETAGAWPFEEARKIVERLKRKPKDEVLFETGYGPSGLPHIGTFGEVARTTMVRHAFRVLTEDK
VKTRLLCFSDDMDGMRKIPDNVPDRAALEPYLQMPLTSVPNPFGGDYPSFGDHNNAMLRRFLDTFGFDYEFASATDYYKT
GKLDAVLLRAAEKYDDIMAVMLPTLGEERQATYSPFLPISPTSGRVLYVPLKAVDAKAGTITFTDEDGVDKTLPVTGGKV
KLQWKPDFGARWAALGVDFEMFGKDHQTNAPVYDRICEILGGVAPEHYVYELFLDENGQKISKSKGNGLTIDEWLTYASP
ESLALYMFQSPRSAKKLHFDVIPKAVDEYFNFLARYPAQDWKLRLGNPVWHIHSGNPPAVDMPVSFSMLLNLASASNTED
EGVLWGFLNRHVEGISPQTHPKLNELVGYAVKYFNDFVKPNKRFRAPDDVERDALATLDAALAALPEGASAEDIQTVLYD
VARPIPRYQDLKAKGATPEKPGVSVEWFNTIYQVLIGQERGPRFGSFVAIYGIPETRALIAKALDGTLAA

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 61333; Mature: 61202

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00152 ATPASE_ALPHA_BETA ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAATTEDLATELRTFAETAGAWPFEEARKIVERLKRKPKDEVLFETGYGPSGLPHIGT
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCC
FGEVARTTMVRHAFRVLTEDKVKTRLLCFSDDMDGMRKIPDNVPDRAALEPYLQMPLTSV
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHCCCCCCCHHHHCHHHHCCHHHC
PNPFGGDYPSFGDHNNAMLRRFLDTFGFDYEFASATDYYKTGKLDAVLLRAAEKYDDIMA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHH
VMLPTLGEERQATYSPFLPISPTSGRVLYVPLKAVDAKAGTITFTDEDGVDKTLPVTGGK
HHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCCCCCCEECCCCCE
VKLQWKPDFGARWAALGVDFEMFGKDHQTNAPVYDRICEILGGVAPEHYVYELFLDENGQ
EEEEECCCCCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCC
KISKSKGNGLTIDEWLTYASPESLALYMFQSPRSAKKLHFDVIPKAVDEYFNFLARYPAQ
EECCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCHHHEEHHHHHHHHHHHHHHHHHCCCC
DWKLRLGNPVWHIHSGNPPAVDMPVSFSMLLNLASASNTEDEGVLWGFLNRHVEGISPQT
CCEEEECCEEEEEECCCCCCEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
HPKLNELVGYAVKYFNDFVKPNKRFRAPDDVERDALATLDAALAALPEGASAEDIQTVLY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DVARPIPRYQDLKAKGATPEKPGVSVEWFNTIYQVLIGQERGPRFGSFVAIYGIPETRAL
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHH
IAKALDGTLAA
HHHHHCCCCCC
>Mature Secondary Structure 
TTAATTEDLATELRTFAETAGAWPFEEARKIVERLKRKPKDEVLFETGYGPSGLPHIGT
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCC
FGEVARTTMVRHAFRVLTEDKVKTRLLCFSDDMDGMRKIPDNVPDRAALEPYLQMPLTSV
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHCCCCCCCHHHHCHHHHCCHHHC
PNPFGGDYPSFGDHNNAMLRRFLDTFGFDYEFASATDYYKTGKLDAVLLRAAEKYDDIMA
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHH
VMLPTLGEERQATYSPFLPISPTSGRVLYVPLKAVDAKAGTITFTDEDGVDKTLPVTGGK
HHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCCCCCCEECCCCCE
VKLQWKPDFGARWAALGVDFEMFGKDHQTNAPVYDRICEILGGVAPEHYVYELFLDENGQ
EEEEECCCCCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCC
KISKSKGNGLTIDEWLTYASPESLALYMFQSPRSAKKLHFDVIPKAVDEYFNFLARYPAQ
EECCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCHHHEEHHHHHHHHHHHHHHHHHCCCC
DWKLRLGNPVWHIHSGNPPAVDMPVSFSMLLNLASASNTEDEGVLWGFLNRHVEGISPQT
CCEEEECCEEEEEECCCCCCEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
HPKLNELVGYAVKYFNDFVKPNKRFRAPDDVERDALATLDAALAALPEGASAEDIQTVLY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DVARPIPRYQDLKAKGATPEKPGVSVEWFNTIYQVLIGQERGPRFGSFVAIYGIPETRAL
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHH
IAKALDGTLAA
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]