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The map label for this gene is yycG [H]

Identifier: 158421976

GI number: 158421976

Start: 405827

End: 407587

Strand: Reverse

Name: yycG [H]

Synonym: AZC_0352

Alternate gene names: 158421976

Gene position: 407587-405827 (Counterclockwise)

Preceding gene: 158421977

Following gene: 158421975

Centisome position: 7.59

GC content: 68.54

Gene sequence:

>1761_bases
ATGCTGATGCAGCGCCGCCCCAAGGACCGCCGCCGCTTCCGGCGCGGCATCCGCAACGTCTCCATCATCGCGGTACTCGG
CGCCTGCGTCTCCATCGCCATCGTGATGGCCGTGGGCTTCGCCAGCTTCCGGGAATTCGCGGCCAGCCAGCATGCGCGCG
AGGATCTGATCTATTCCTCCAGCATCCGCGCGGAATTGCAGTCGATCTATGAGCAGTTGCTGACGGTGGAGAGCGCCACG
CGCGGCTTCATCATCACCGGCGAAGCCGAATTCCGCCCGCCGCTCGACGAGGACCGGACGCGCATCCTCGCCCGCATCGC
GGCCGTGACGAAATTCGCCGTCGAACGCCCGGAGCACACTGACGACCTTGCCCGCCTCAAGAGGCTCGCAGAGGCGGAGC
TGCGGCTGCTGGGAGAGATGATCGACGCCCGCATGCATTCGGATGCGACGCCCGCCGGCAGCATCCTCCAGGTGCGGCAG
AGCAAGGGCCTGATGGACCAGATCGCCGAGACGGTGGAGAGCATCGCCGAGGCGGAAATCGGCGCCATCAACGCCCGCAC
CCAGGAGGTGCGCGTCGTCGGCCAGCGCACCAAGACAACCCTGCTCGCCCTTCTCGGCGCGGCCATCGCCGTGGTCTTCG
GCTCCACCGCCGTGATGCTCACCCATCTGGTGGGCCGCCGCCGGGCGGAGCGGGCGCTGGGCGATGCCCTCTCGCGCCAG
CGGGCCATTCTCGCCAGCGCCATCGATTCCATCGTCACGGTGAATGTCGAGGGTCGCATCGAGAGCGCCAATCCCGCCAC
CACGCGCCTGCTCGGCTGGCAGCCGGAGGAGATTGCGGGCAAGCCGCTCGGCACGCTGTTCAGCCTGCCGGAAGGCACCA
CGCCCACCGATTTCATGACAGAACTGTCCTCGACCGCCAAGGACGGCGGCGGCGTGCGCGAACTGATCGGGCTGCGCAAG
GACGGCGGCACTGTGCCCGTGGACGTGGCCATCGGCCGGATGCGGGACAGCGGCGGCCAGAATCTCGTTGCCGTGCTGCA
CGACATCACCGAGCGCAAGCGGGCCGAGGTGATGAAGAACGAATTCGTCTCCACCGTCAGCCACGAGCTGCGCACCCCGC
TCACCTCCATCGCCGGCTCGCTCGGCCTGCTGGCCGGCGGCGCCACCGGCTCCCTGCCGGAAGGGGCGCAGAGGCTCGTC
ACCATCGCCTCCCAGAACTGCCGGCGGCTGGTGCGGCTCATCAACGACATTCTCGACATCGAGAAGATGCAGTCCTCGGG
CATCACCTTCGCCCGCGACACCGTCTCGCTGGCCGAGGTCGCCGAGCGGTCGGTGGAGCAGAACAGCGGCTTTGCGCTCG
AACACCAGGTCGCCCTCACCCTTGAGGTGGAGCCGGGCGACCTGCGGGTGACGGGCGATGCGGACCGGCTGATCCAGGTG
CTGACCAACCTTCTGTCCAATGCGGTGAAATTCTCCCCCGCCGGCAGCACGGTGGAGGTGAGCGTCGCCCGCCGCGGCGA
CCATGTGCGGGCCACCGTGCGCGATCACGGCATGGGCATTCCGGAGAGCTTCCGCTCCGCCATCTTCACCCGCTTCGCGC
AGGCGGACAATTCCGATACCCGCCAGCGGGGCGGCACCGGGCTTGGCCTCGCCATCGCCCGCGAGATCGCCGATCATCAC
GACGGGACGCTCAGCTTCGAGACCGAGGAAGGCGTGGGCACCGCCTTTCATCTGGACTTGCCGGCGCTCGAGGCGCCATA
G

Upstream 100 bases:

>100_bases
GTCTTTCTCTCGGCGGCGGCATCCTGTTACGGTTCGCCATGCCCTGCCGATCGCGCGCCTCCCTGCCCTCCGCCGCCGCA
CTCCCGCGGAGCGGCCTGTC

Downstream 100 bases:

>100_bases
CGGAACGTCCGGACAGCCGCGAGATCCGCCATGGCGCTCACCATCCTCTATGTGGACGACGAAGCCGACATCCGCGAGAT
CGCGAGCCTGTCGCTCGGGC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MLMQRRPKDRRRFRRGIRNVSIIAVLGACVSIAIVMAVGFASFREFAASQHAREDLIYSSSIRAELQSIYEQLLTVESAT
RGFIITGEAEFRPPLDEDRTRILARIAAVTKFAVERPEHTDDLARLKRLAEAELRLLGEMIDARMHSDATPAGSILQVRQ
SKGLMDQIAETVESIAEAEIGAINARTQEVRVVGQRTKTTLLALLGAAIAVVFGSTAVMLTHLVGRRRAERALGDALSRQ
RAILASAIDSIVTVNVEGRIESANPATTRLLGWQPEEIAGKPLGTLFSLPEGTTPTDFMTELSSTAKDGGGVRELIGLRK
DGGTVPVDVAIGRMRDSGGQNLVAVLHDITERKRAEVMKNEFVSTVSHELRTPLTSIAGSLGLLAGGATGSLPEGAQRLV
TIASQNCRRLVRLINDILDIEKMQSSGITFARDTVSLAEVAERSVEQNSGFALEHQVALTLEVEPGDLRVTGDADRLIQV
LTNLLSNAVKFSPAGSTVEVSVARRGDHVRATVRDHGMGIPESFRSAIFTRFAQADNSDTRQRGGTGLGLAIAREIADHH
DGTLSFETEEGVGTAFHLDLPALEAP

Sequences:

>Translated_586_residues
MLMQRRPKDRRRFRRGIRNVSIIAVLGACVSIAIVMAVGFASFREFAASQHAREDLIYSSSIRAELQSIYEQLLTVESAT
RGFIITGEAEFRPPLDEDRTRILARIAAVTKFAVERPEHTDDLARLKRLAEAELRLLGEMIDARMHSDATPAGSILQVRQ
SKGLMDQIAETVESIAEAEIGAINARTQEVRVVGQRTKTTLLALLGAAIAVVFGSTAVMLTHLVGRRRAERALGDALSRQ
RAILASAIDSIVTVNVEGRIESANPATTRLLGWQPEEIAGKPLGTLFSLPEGTTPTDFMTELSSTAKDGGGVRELIGLRK
DGGTVPVDVAIGRMRDSGGQNLVAVLHDITERKRAEVMKNEFVSTVSHELRTPLTSIAGSLGLLAGGATGSLPEGAQRLV
TIASQNCRRLVRLINDILDIEKMQSSGITFARDTVSLAEVAERSVEQNSGFALEHQVALTLEVEPGDLRVTGDADRLIQV
LTNLLSNAVKFSPAGSTVEVSVARRGDHVRATVRDHGMGIPESFRSAIFTRFAQADNSDTRQRGGTGLGLAIAREIADHH
DGTLSFETEEGVGTAFHLDLPALEAP
>Mature_586_residues
MLMQRRPKDRRRFRRGIRNVSIIAVLGACVSIAIVMAVGFASFREFAASQHAREDLIYSSSIRAELQSIYEQLLTVESAT
RGFIITGEAEFRPPLDEDRTRILARIAAVTKFAVERPEHTDDLARLKRLAEAELRLLGEMIDARMHSDATPAGSILQVRQ
SKGLMDQIAETVESIAEAEIGAINARTQEVRVVGQRTKTTLLALLGAAIAVVFGSTAVMLTHLVGRRRAERALGDALSRQ
RAILASAIDSIVTVNVEGRIESANPATTRLLGWQPEEIAGKPLGTLFSLPEGTTPTDFMTELSSTAKDGGGVRELIGLRK
DGGTVPVDVAIGRMRDSGGQNLVAVLHDITERKRAEVMKNEFVSTVSHELRTPLTSIAGSLGLLAGGATGSLPEGAQRLV
TIASQNCRRLVRLINDILDIEKMQSSGITFARDTVSLAEVAERSVEQNSGFALEHQVALTLEVEPGDLRVTGDADRLIQV
LTNLLSNAVKFSPAGSTVEVSVARRGDHVRATVRDHGMGIPESFRSAIFTRFAQADNSDTRQRGGTGLGLAIAREIADHH
DGTLSFETEEGVGTAFHLDLPALEAP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=37.8260869565217, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786600, Length=361, Percent_Identity=28.808864265928, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=32.618025751073, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=33.0578512396694, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=33.1983805668016, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=29.3617021276596, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=32.618025751073, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788549, Length=382, Percent_Identity=24.869109947644, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=30.9623430962343, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=30, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=30.0847457627119, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790300, Length=359, Percent_Identity=27.5766016713092, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786783, Length=269, Percent_Identity=26.7657992565056, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=277, Percent_Identity=25.6317689530686, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=30.7053941908714, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=240, Percent_Identity=28.75, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=108, Percent_Identity=34.2592592592593, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=69, Percent_Identity=44.9275362318841, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63235; Mature: 63235

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMQRRPKDRRRFRRGIRNVSIIAVLGACVSIAIVMAVGFASFREFAASQHAREDLIYSS
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIRAELQSIYEQLLTVESATRGFIITGEAEFRPPLDEDRTRILARIAAVTKFAVERPEHT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
DDLARLKRLAEAELRLLGEMIDARMHSDATPAGSILQVRQSKGLMDQIAETVESIAEAEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GAINARTQEVRVVGQRTKTTLLALLGAAIAVVFGSTAVMLTHLVGRRRAERALGDALSRQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAILASAIDSIVTVNVEGRIESANPATTRLLGWQPEEIAGKPLGTLFSLPEGTTPTDFMT
HHHHHHHHHHHEEEEECCEEECCCCCHHHCCCCCCHHHCCCCCHHHHCCCCCCCCHHHHH
ELSSTAKDGGGVRELIGLRKDGGTVPVDVAIGRMRDSGGQNLVAVLHDITERKRAEVMKN
HHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHEHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EFVSTVSHELRTPLTSIAGSLGLLAGGATGSLPEGAQRLVTIASQNCRRLVRLINDILDI
HHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMQSSGITFARDTVSLAEVAERSVEQNSGFALEHQVALTLEVEPGDLRVTGDADRLIQV
HHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEECCHHHHHHH
LTNLLSNAVKFSPAGSTVEVSVARRGDHVRATVRDHGMGIPESFRSAIFTRFAQADNSDT
HHHHHHHHEEECCCCCEEEEEEECCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCH
RQRGGTGLGLAIAREIADHHDGTLSFETEEGVGTAFHLDLPALEAP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MLMQRRPKDRRRFRRGIRNVSIIAVLGACVSIAIVMAVGFASFREFAASQHAREDLIYSS
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIRAELQSIYEQLLTVESATRGFIITGEAEFRPPLDEDRTRILARIAAVTKFAVERPEHT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCH
DDLARLKRLAEAELRLLGEMIDARMHSDATPAGSILQVRQSKGLMDQIAETVESIAEAEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GAINARTQEVRVVGQRTKTTLLALLGAAIAVVFGSTAVMLTHLVGRRRAERALGDALSRQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAILASAIDSIVTVNVEGRIESANPATTRLLGWQPEEIAGKPLGTLFSLPEGTTPTDFMT
HHHHHHHHHHHEEEEECCEEECCCCCHHHCCCCCCHHHCCCCCHHHHCCCCCCCCHHHHH
ELSSTAKDGGGVRELIGLRKDGGTVPVDVAIGRMRDSGGQNLVAVLHDITERKRAEVMKN
HHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHEHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EFVSTVSHELRTPLTSIAGSLGLLAGGATGSLPEGAQRLVTIASQNCRRLVRLINDILDI
HHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKMQSSGITFARDTVSLAEVAERSVEQNSGFALEHQVALTLEVEPGDLRVTGDADRLIQV
HHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEECCHHHHHHH
LTNLLSNAVKFSPAGSTVEVSVARRGDHVRATVRDHGMGIPESFRSAIFTRFAQADNSDT
HHHHHHHHEEECCCCCEEEEEEECCCCCEEEEHHHCCCCCCHHHHHHHHHHHHHCCCCCH
RQRGGTGLGLAIAREIADHHDGTLSFETEEGVGTAFHLDLPALEAP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]